A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis

Vandal, Omar H, Pierini, Lynda M, Schnappinger, Dirk, Nathan, Carl F, Ehrt, Sabine·2008·Nature Medicine

DOI 10.1038/nm.1795

Cited by (370)

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Tracy L. Keiser, Georgiana E. Purdy · 2017 · Microbiology Spectrum
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Timothy A. Bates, Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu Kebede Gurmessa, Ilaria R Merutka, Shandee D Dixon, Anthony D. Shumate, Abigail R Groncki, Matthew AH Parson et al. · 2023 · eLife
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Takehiro Kado, Zarina Akbary, Daisuke Motooka, Ian L. Sparks, Emily S. Melzer, Shota Nakamura, Enrique Rojas, Yasu S. Morita, M. Sloan Siegrist · 2023 · eLife
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Rishabh Sharma, Deepa Keshari, Kumar Sachin Singh, Shailendra Yadav, Sudheer Kumar Singh · 2016 · Scientific Reports
Host-directed therapy against tuberculosis: Concept and recent developments
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Abirami Kugadas, Elise A. Lamont, John P. Bannantine, Fernanda Miyagaki Shoyama, Evan Pierce Brenner, Harish K. Janagama, Srinand Sreevatsan · 2016 · Frontiers in Cellular and Infection Microbiology
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Swati Singh, Nikita Goswami, Anil K. Tyagi, Garima Khare · 2019 · Journal of Biological Chemistry
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Xiaomeng Pei, Mingxing Liu, Hong Zhou, Hongjie Fan · 2020 · Virulence
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Jie Wu, Ran Mu, Mingna Sun, Nan Zhao, Miaomiao Pan, Hongshuang Li, Yi Dong, Zhaogang Sun, Jie Bai, Minwan Hu et al. · 2019 · ACS Infectious Diseases
Glutamate decarboxylase confers acid tolerance and enhances survival of mycobacteria within macrophages
Rupal Rai, Bijina J. Mathew, Rashmi Chourasia, Anirudh K. Singh, Shivendra Kumar Chaurasiya · 2025 · Journal of Biological Chemistry
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Florian Bourdeaux, Christopher A. Hammer, Stephan Vogt, Felix Schweighöfer, Gilbert Nöll, Josef Wachtveitl, Martin Grininger · 2018 · ACS Infectious Diseases
Paradigm redux—Mycobacterium avium subspecies paratuberculosis-macrophage interactions show clear variations between bovine and human physiological body temperatures
Elise A. Lamont, Srinand Sreevatsan · 2010 · Microbial Pathogenesis
Role of host- and pathogen-associated lipids in directing the immune response in mycobacterial infections, with emphasis onMycobacterium aviumsubsp.paratuberculosis
Shyamala Thirunavukkarasu, Kumudika de Silva, Karren M. Plain, Richard J. Whittington · 2014 · Critical Reviews in Microbiology
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Mayumi Mori, Ravindra Mode, Jean Pieters · 2018 · Frontiers in Cellular and Infection Microbiology
Acid stress response of a mycobacterial proteome: insight from a gene ontology analysis.
Bryan AP Roxas, Qingbo Li · 2009 · PubMed Central
Mycobacterium tuberculosis Adaptation to Survival in a Human Host
Beatrice Saviola · 2013 · InTech eBooks
Elucidating the functional role of Mycobacterium smegmatis recX in stress response
Deepika Prasad, Divya Arora, Vinay Kumar Nandicoori, K. Muniyappa · 2019 · Scientific Reports
Mycobacterium tuberculosis Phosphate Uptake System Component PstA2 Is Not Required for Gene Regulation or Virulence
Anna D. Tischler, Rachel L. Leistikow, Pavithra Ramakrishnan, Martin I. Voskuil, John D. McKinney · 2016 · PLoS ONE
Heterogeneity in the endocytic capacity of individual macrophage in a population determines its subsequent phagocytosis, infectivity and subcellular trafficking
Kuldeep Singh Sachdeva, Manisha Goel, Varadharajan Sundaramurthy · 2020 · Traffic
Correction: Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis
Crystal M. Darby, Helgi I. IngÃ lfsson, Xiuju Jiang, Chun Fang Shen, Mingna Sun, Nan Zhao, Kristin E. Burns, Gang Liu, Sabine Ehrt, J. David Warren et al. · 2013 · PLoS ONE
Novel insights into ATP-Stimulated Cleavage of branched DNA and RNA Substrates through Structure-Guided Studies of the Holliday Junction Resolvase RuvX
Manoj Thakur, Disha Mohan, Ankur Kumar Singh, Ankit Agarwal, B. Gopal, Kalappa Muniyappa · 2021 · Journal of Molecular Biology
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Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci · 2025 · FEBS Letters