Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Lei, Peng, Ayton, Scott, Finkelstein, David I, Spoerri, Loredana, Ciccotosto, Giuseppe D, Wright, David K, Wong, Bruce X W, Adlard, Paul A +9 more·2012·Nature Medicine

Cited by (596)

Items 301–400 of 596

  1. The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice
    Zhongda Li, Haiyan Li, Shaomeng Kang, Yange Cui, Huiwen Zheng, Peina Wang, Kang Han, Peng Yu, Yan‐Zhong Chang · 2022 · Cell Death and Disease
  2. Targeting Biometals in Alzheimer’s Disease with Metal Chelating Agents Including Coumarin Derivatives
    Adrián Gucký, Slávka Hamuľaková · 2024 · CNS Drugs
  3. A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases
    Kyoka Hoshi, Yuka Matsumoto, Hiromi Ito, Kiyoshi Saito, Takashi Honda, Yoshiki Yamaguchi, Yasuhiro Hashimoto · 2017 · Biochimica et Biophysica Acta (BBA) - General Subjects
  4. Tau Abnormalities and the Potential Therapy in Alzheimer’s Disease
    Hasan A. M. M. Almansoub, Hui Ru Tang, Ying Wu, Ding‐Qi Wang, Yacoubou Abdoul Razak Mahaman, Na Wei, Yusra A. M. Almansob, Wei He, Dan Liu · 2018 · Journal of Alzheimer s Disease
  5. The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy
    Shalini S. Rao, Stuart D Portbury, Larissa Lago, Ashley Ian Bush, Paul Anthony Adlard · 2020 · Journal of Alzheimer s Disease
  6. RETRACTED: The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy1
    Shalini S. Rao, Stuart D Portbury, Larissa Lago, Ashley Ian Bush, Paul Anthony Adlard · 2020 · Journal of Alzheimer s Disease · Retracted
  7. Iron Redox Chemistry and Implications in the Parkinson’s Disease Brain
    Abeyawardhane, Dinendra L., Lucas, Heather R. · 2019 · Oxidative Medicine and Cellular Longevity
  8. Iron and Targeted Iron Therapy in Alzheimer’s Disease
    Jian Wang, Jiaying Fu, Yuanxin Zhao, Qingqing Liu, Xiaoyu Yan, Jing Su · 2023 · International Journal of Molecular Sciences
  9. Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau
    Ashenafi Haileyesus Betrie, Scott Ayton, Ashley Ian Bush, James A. Angus, Peng Lei, Christine E. Wright · 2017 · Journal of Alzheimer s Disease
  10. Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D
    Claudia Jara, Waldo F. Cerpa, Cheril Tapia‐Rojas, Rodrigo A. Quintanilla · 2021 · Frontiers in Neuroscience
  11. Parkinson’s Disease Dementia: Synergistic Effects of Alpha-Synuclein, Tau, Beta-Amyloid, and Iron
    Jiajun Han, Yaohua Fan, Peipei Wu, Zifeng Huang, Xinrong Li, Lijun Zhao, Yichun Ji, Meiling Zhu · 2021 · Frontiers in Aging Neuroscience
  12. Tau Post-Translational Modifications: Potentiators of Selective Vulnerability in Sporadic Alzheimer’s Disease
    Trae Carroll, Sanjib K Guha, Keith W. Nehrke, Gail V.W. Johnson · 2021 · Biology
  13. Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent
    Miranda E. Orr, Valentina Rose Garbarino, Angelica Salinas, Rochelle Buffenstein · 2014 · Neurobiology of Aging
  14. Ferroptosis and its contribution to cognitive impairment in Alzheimer’s disease: mechanisms and therapeutic potential
    Gyas Khan, Md Sadique Hussain, Yumna Khan, Rabab Fatima, Sarfaraz Ahmad, Ayesha Sultana, Prawez Alam · 2025 · Brain Research
  15. Quantitative Proteomic Analyses of Cerebrospinal Fluid Using iTRAQ in a Primate Model of Iron Deficiency Anemia
    Stephanie M. Patton, Christopher L. Coe, Gabriele R. Lubach, James R. Connor · 2012 · Developmental Neuroscience
  16. Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies
    Jesús Ávila, Noemí Pallas‐Bazarra, Marta Bolós, Carmen Laura Sayas, Félix Hernández · 2015 · Expert Opinion on Therapeutic Targets
  17. Neural circuit changes in neurological disorders: Evidence from in vivo two-photon imaging
    Huan Xiong, Fei Tang, Yujie Guo, Ruxiang Xu, Lei Peng · 2023 · Ageing Research Reviews
  18. Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies
    Lidia Bakota, Abdala Mumuni Ussif, Gunnar Jeserich, Roland Brandt · 2017 · Molecular and Cellular Neuroscience
  19. Tau suppresses microtubule-regulated pancreatic insulin secretion
    Salvatore P. Mangiafico, Qing‐zhang Tuo, Xiao-Lan Li, Yu Liu, Christian Haralambous, Xulong Ding, Scott Ayton, Qing Wang, D. Ross Laybutt, Jeng Yie Chan et al. · 2023 · Molecular Psychiatry
  20. Trasferrin receptor 2 gene regulation by microRNA 221 in SH-SY5Y cells treated with MPP+ as Parkinson's disease cellular model
    Roberta Asci, Fara Vallefuoco, Immacolata Andolfo, Mariasole Bruno, Luigia De Falco, Achille Iolascon · 2013 · Neuroscience Research
  21. Multi-Target Neuroprotection of Thiazolidinediones on Alzheimer’s Disease via Neuroinflammation and Ferroptosis
    Jiahui Yang, Xiaohua Shi, Yingying Wang, Ming Ma, Hongyu Liu, Jiaoqi Wang, Zhongxin Xu · 2023 · Journal of Alzheimer s Disease
  22. Regulated cell death in hypoxic-ischaemic encephalopathy: recent development and mechanistic overview
    Lingzhi Wu, Enqiang Chang, Hailin Zhao, Daqing Ma · 2024 · Cell Death Discovery
  23. Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons
    Carlos G. Sanchez, Christopher M. Acker, Audrey J. Gray, Malini Varadarajan, Cheng Song, Nadire R. Cochran, Steven Paula, Alicia Lindeman, Shaojian An, Gregory McAllister et al. · 2021 · Communications Biology
  24. Current understanding of the interactions between metal ions and Apolipoprotein E in Alzheimer’s disease
    Yanhui Zhang, Huiling Gao, Wei Zheng, He Jax Xu · 2022 · Neurobiology of Disease
  25. Characterizing brain iron deposition in subcortical ischemic vascular dementia using susceptibility-weighted imaging: An in vivo MR study
    Chen Liu, Chuanming Li, Jun Yang, Li Gui, Lu Zhao, Alan Charles Evans, Xuntao Yin, Jian Wang · 2015 · Behavioural Brain Research
  26. Impaired burrowing is the most prominent behavioral deficit of aging htau mice
    Philippine C. Geiszler, Matthew Richard Barron, Marie‐Christine Pardon · 2016 · Neuroscience
  27. Generation of tau dephosphorylation-targeting chimeras for the treatment of Alzheimer’s disease and related tauopathies
    Jingfen Su, Yue Xiao, Linyu Wei, Huiyang Lei, Fei Sun, Weixia Wang, Jun Yin, Rui Xiong, Shihong Li, Pei Zhang et al. · 2024 · 中国科学通报:英文版
  28. The role of iron transporters and regulators in Alzheimer’s disease and Parkinson’s disease: Pathophysiological insights and therapeutic prospects
    Siqi Tian, Bing Wang, Yiqian Ding, Yu Long Zhang, Peng Yu, Yan-Zhong Chang, Guofen Gao · 2024 · Biomedicine & Pharmacotherapy
  29. Protein Misfolding in Prion and Prion-Like Diseases: Reconsidering a Required Role for Protein Loss-of-Function
    Patricia L.A. Leighton, W. Ted Allison · 2016 · Journal of Alzheimer s Disease
  30. Biomonitorization of iron accumulation in the substantia nigra from Lewy body disease patients
    Belén Fernández, Isidró Ferrer, Fernando Gil, Sabine Hilfiker · 2017 · Toxicology Reports
  31. Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE2 and PGD2 at the early stage of Alzheimer’s Disease
    Chen-Di Lu, Ji-Kang Ma, Zheng-Yang Luo, Qunxi Tai, Pu Wang, Pei-Pei Guan · 2018 · Aging
  32. Correction: Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
    Jianfang Chen, Eileen S. Marks, Barry Chi Hong Lai, Zhaojie Zhang, James A. Duce, Linh Q. Lam, Irene Volitakis, Ashley Ian Bush, Steven M. Hersch, Jonathan H. Fox · 2013 · PLoS ONE
  33. Are high copper levels related to Alzheimer’s and Parkinson’s diseases? A systematic review and meta-analysis of articles published between 2011 and 2022
    Fabielly Scolari Grotto, Viviane Glaser · 2023 · BioMetals
  34. Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease
    Michael P. Gotsbacher, Thomas J. Telfer, Paul Kenneth Witting, Kay L. Double, David Isaac Finkelstein, Rachel Codd · 2017 · Metallomics
  35. Friend or foe: role of pathological tau in neuronal death
    Moxin Wu, Zhiying Chen, Min Hua Jiang, Bing Bao, Dongling Li, Xiaoping Yin, Xueren Wang, Dan Liu, Ling‐Qiang Zhu · 2023 · Molecular Psychiatry
  36. Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study
    Xiaxuan Huang, Hongtao Cheng, Shiqi Yuan, Yitong Ling, Shanyuan Tan, Yonglan Tang, Chen Niu, Jun Lyu · 2023 · BMC Geriatrics
  37. The potential roles of salivary biomarkers in neurodegenerative diseases
    Lingling Jiao, Hui-Lin Dong, Meng-Meng Liu, Peng-Lin Wu, Yi Cao, Yuan E. Zhang, Fu-Gao Gao, Huai-Yuan Zhu · 2024 · Neurobiology of Disease
  38. The Irony of Iron: The Element with Diverse Influence on Neurodegenerative Diseases
    Seojin Lee, Gábor Géza Kovács · 2024 · International Journal of Molecular Sciences
  39. Interrogating Parkinson's disease associated redox targets: Potential application of CRISPR editing
    Margarita A. Artyukhova, Yulia Y. Tyurina, Charleen T. Chu, Tatiana M. Zharikova, Hülya Bayır, Valerian E. Kagan, Peter S. Timashev · 2019 · Free Radical Biology and Medicine
  40. Iron overload resulting from the chronic oral administration of ferric citrate induces parkinsonism phenotypes in middle-aged mice
    Chao Huang, Wenjing Ma, Qihui Luo, Liangqin Shi, Yu Xia, Chengjie Lao, Wentao Liu, Yuanfeng Zou, Anchun Cheng, Riyi Shi et al. · 2019 · Aging
  41. RETRACTED: Characterising the spatial and temporal brain metal profile in a mouse model of tauopathy
    Shalini S. Rao, Larissa Lago, Raquel González de Vega, Lisa Bray, Dominic James Hare, David Clases, Philip Doble, Paul Anthony Adlard · 2019 · Metallomics · Retracted
  42. Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation
    Yating Zhang, Xue Bai, Yi Zhang, Shanshan Yao, Yiduo Cui, Linhao You, Peng Yu, Yan‐Zhong Chang, Guofen Gao · 2022 · Molecular Neurobiology
  43. Ferroptosis: a potential therapeutic target for Alzheimer’s disease
    Lan Yang, Jianfei Nao · 2022 · Reviews in the Neurosciences
  44. Imbalance of Essential Metals in Traumatic Brain Injury and Its Possible Link with Disorders of Consciousness
    Rosanna Squitti, Giuseppe Reale, Vincenzo Tondolo, Daniela Crescenti, Sonia Bellini, Marco Moci, Pietro Caliandro, Luca Padua, Mauro Ciro Antonio Rongioletti · 2023 · International Journal of Molecular Sciences
  45. Molecular mechanism and potential therapeutic targets of necroptosis and ferroptosis in Alzheimer's disease
    Sara Chavoshinezhad, Elmira Beirami, Esmael Izadpanah, Marco Feligioni, Kambiz Hassanzadeh · 2023 · Biomedicine & Pharmacotherapy
  46. Bioavailable Trace Metals in Neurological Diseases
    Aurélia Poujois, Jean-Christophe Devedjian, Caroline Moreau, David Devos, Pascal Chaine, France Woimant, James A. Duce · 2016 · Current Treatment Options in Neurology
  47. Targeting E. coli invasion of the blood–brain barrier for investigating the pathogenesis and therapeutic development of E. coli meningitis
    Ningyu Zhu, Wei Liu, Atish Kumar Prakash, Chengxian Zhang, Kwang Sik Kim · 2020 · Cellular Microbiology
  48. Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence
    Jana Key, Nesli-Ece Şen, Aleksandar Arsović, Stella Krämer, Robert Hülse, Natasha Nadeem Khan, David Meierhofer, Suzana Gispert, Gabriele Koepf, Georg W. J. Auburger · 2020 · Cells
  49. Biomaterial and tissue-engineering strategies for the treatment of brain neurodegeneration
    Bridget Martinez, Philip V. Peplow · 2022 · Neural Regeneration Research
  50. Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies
    Yvette Akwa, Chiara Di Malta, Fátima Zallo, Elise Gondard, Adele Lunati, Lara Z. Diaz-de-Grenu, Angela Zampelli, Anne Boiret, Sara Santamaria, Maialen Martinez-Preciado et al. · 2022 · Autophagy
  51. Towards early detection of neurodegenerative diseases: A gut feeling
    Stephanie Makdissi, Brendon Parsons, Francesca Di Cara · 2023 · Frontiers in Cell and Developmental Biology
  52. Iron Dyshomeostasis Induces Binding of APP to BACE1 for Amyloid Pathology, and Impairs APP/Fpn1 Complex in Microglia: Implication in Pathogenesis of Cerebral Microbleeds
    Li Gong, Xiang-Zhu Tian, Jing Zhou, Qiong Dong, Yan Tan, You Lü, Jiayan Wu, Yanxin Zhao, Xueyuan Liu · 2019 · Cell Transplantation
  53. Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease
    S. Mostafa Hosseinpour-Mashkani, David Bishop, Newsha Raoufi-Rad, Paul Anthony Adlard, Olga Shimoni, Mojtaba Golzan · 2023 · Cells
  54. Traumatic brain injury and the development of parkinsonism: Understanding pathophysiology, animal models, and therapeutic targets
    Smrithi Padmakumar, Praveen Kulkarni, Craig F. Ferris, Benjamin Saul Bleier, Mansoor M. Amiji · 2022 · Biomedicine & Pharmacotherapy
  55. How Well Do Rodent Models of Parkinson’s Disease Recapitulate Early Non-Motor Phenotypes? A Systematic Review
    Tracy D. Zhang, Scott Kolbe, Leah C. Beauchamp, Ella Woodbridge, David Isaac Finkelstein, Emma L. Burrows · 2022 · Biomedicines
  56. Alzheimer's Disease and Its Potential Alternative Therapeutics.
    Brent R. Kisby, Juliet T. Jarrell, Agar Me, Cohen Ds, Rosin Er, Cahill Cm, Jack T. Rogers, Xudong Huang · 2019 · PubMed
  57. Deferiprone Treatment in Aged Transgenic Tau Mice Improves Y-Maze Performance and Alters Tau Pathology
    Shalini S. Rao, Larissa Lago, Irene Volitakis, Jay J. Shukla, Gawain McColl, David Isaac Finkelstein, Paul Anthony Adlard · 2021 · Neurotherapeutics · Retracted
  58. CSF ferritin in the clinicopathological progression of Alzheimer’s disease and associations with APOE and inflammation biomarkers
    Scott Ayton, Shorena Janelidze, Pawel Kalinowski, Sebastian Palmqvist, Abdel Ali Belaidi, Erik Stomrud, Anne Roberts, Blaine Russell Roberts, Oskar Hansson, Ashley Ian Bush · 2022 · Journal of Neurology Neurosurgery & Psychiatry
  59. Potential molecular mechanism of exercise reversing insulin resistance and improving neurodegenerative diseases
    Jiawen Shen, Xianping Wang, Minghui Wang, Hu Zhang · 2024 · Frontiers in Physiology
  60. Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau
    Fadi Mikhail, Noel Ylagan Calingasan, Luca Parolari, A. Subramanian, Liuliu Yang, M. Flint Beal · 2015 · Human Molecular Genetics
  61. Magnetic Resonance Imaging (MRI) to Study Striatal Iron Accumulation in a Rat Model of Parkinson’s Disease
    Ana Virel, Erik Faergemann, Greger Orädd, Ingrid Strömberg · 2014 · PLoS ONE
  62. Upregulated levels and pathological aggregation of abnormally phosphorylated Tau-protein in children with neurodevelopmental disorders
    Marija Rankovic, Markus Zweckstetter · 2018 · Neuroscience & Biobehavioral Reviews
  63. Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer’s Disease
    Jun-Peng Guo, Jin‐Xiu Pan, Lei Xiong, Wen-Fang Xia, Shun Cui, Wen‐Cheng Xiong · 2015 · PLoS ONE
  64. Cell‐Specific Dysregulation of Iron and Oxygen Homeostasis as a Novel Pathophysiology in PSP
    Seojin Lee, Iván Martínez-Valbuena, Carlos E. de Andrea, María Villalba-Esparza, Suganthi Ilaalagan, Blas Couto, Naomi P. Visanji, Anthony Edward Lang, Gábor Géza Kovács · 2022 · Annals of Neurology
  65. Heparan Sulfate Proteoglycans in Tauopathy
    Yanan Zhu, Lauren A. Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J. Blair, Robert J. Linhardt, Lianchun Wang · 2022 · Biomolecules
  66. Copper(II) complexation of tacrine hybrids with potential anti-neurodegenerative roles
    Catarina Quintanova, Rangappa Sangappa Keri, Sı́lvia Chaves, Maria Amélia Santos · 2015 · Journal of Inorganic Biochemistry
  67. A neuroscience perspective of the gut theory of Parkinson's disease
    Lisa Mary Smith, Louise C. Parr‐Brownlie · 2018 · European Journal of Neuroscience
  68. Brain Zinc Deficiency Exacerbates Cognitive Decline in the R6/1 Model of Huntington's Disease
    Scott Ayton, Peng Lei, Ambili Thoppuvalappil Appukuttan, Thibault Renoir, Simote Totauhelotu Foliaki, Feng Chen, Paul Anthony Adlard, Anthony John Hannan, Ashley Ian Bush · 2019 · Neurotherapeutics
  69. Clearance of intracellular tau protein from neuronal cells via VAMP8-induced secretion
    Julie Pilliod, Alexandre Desjardins, Camille Pernègre, Hélène Jamann, Catherine Larochelle, Edward A. Fon, Nicole M. Leclerc · 2020 · Journal of Biological Chemistry
  70. Ablation of tau causes an olfactory deficit in a murine model of Parkinson’s disease
    Leah C. Beauchamp, Jacky Chan, Lin Wai Hung, Benjamin Scott Padman, Laura J. Vella, Xiang M. Liu, Bradley M. Coleman, Ashley Ian Bush, Michael Lazarou, Andrew Francis Hill et al. · 2018 · Acta Neuropathologica Communications
  71. Experimental Models of Tauopathy – From Mechanisms to Therapies
    Julika J. Götz, Jürgen Götz · 2019 · Advances in experimental medicine and biology
  72. Targeting Tau to Treat Clinical Features of Huntington's Disease
    Maria Masnata, Shireen Salem, Aurélie de Rus Jacquet, Mehwish Anwer, Francesca Cicchetti · 2020 · Frontiers in Neurology
  73. Ferroportin1 in the brain
    Zhong‐Ming Qian, Wei Li, Qian Guo · 2023 · Ageing Research Reviews
  74. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells
    Takayoshi Yamauchi, Masaaki Nishiyama, Toshiro Moroishi, Atsuki Kawamura, Keiichi I. Nakayama · 2017 · Molecular and Cellular Biology
  75. Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn‐independent effect of tau on calcium
    Guanghao Liu, Ramasamy Thangavel, Jacob Rysted, Yohan Kim, Meghan B. Francis, Eric Adams, Zhihong Lin, Rebecca J. Taugher, John A. Wemmie, Yuriy M. Usachev et al. · 2019 · Journal of Neuroscience Research
  76. Ferroptosis and cognitive impairment: Unraveling the link and potential therapeutic targets
    Soudabeh Naderi, Fariba Khodagholi, Mahyar Janahmadi, Fereshteh Motamedi, Abolfazl Torabi, Zehra Batool, Mahshad Fadaeimoghadam Heydarabadi, Hamid Gholami Pourbadie · 2024 · Neuropharmacology
  77. Unscrambling the Role of Redox-Active Biometals in Dopaminergic Neuronal Death and Promising Metal Chelation-Based Therapy for Parkinson’s Disease
    Alfredo González-Alcocer, Ana Patricia Duarte-Jurado, Adolfo Soto‐Domínguez, María de Jesús Loera‐Arias, Eliud Enrique Villarreal‐Silva, Odila Saucedo Cárdenas, Roberto Montes‐de‐Oca‐Luna, Aracely García‐García, Humberto Rodríguez‐Rocha · 2023 · International Journal of Molecular Sciences
  78. Transgenic Mouse Models for the Study of Neurodegenerative Diseases
    Alba Marín‐Moreno, Sara Canoyra, Natalia Fernández‐Borges, Juan Carlos Espinosa, Juan María Torres · 2023 · Frontiers in Bioscience-Landmark
  79. Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue
    Christina Victoria Isabella Tauber, Sigrid C. Schwarz, Thomas W. Rösler, Thomas Arzberger, Steve Gentleman, Otto Windl, Mandy Krumbiegel, André Reis, Viktoria Ruf, Jochen Wolfgang Herms et al. · 2023 · Acta Neuropathologica Communications
  80. Role of metal ions in the cognitive decline of Down syndrome
    Nakisa Malakooti, Melanie A. Pritchard, Paul Anthony Adlard, David Isaac Finkelstein · 2014 · Frontiers in Aging Neuroscience
  81. The Compound ATH434 Prevents Alpha-Synuclein Toxicity in a Murine Model of Multiple System Atrophy
    David Isaac Finkelstein, Jay J. Shukla, Robert A. Cherny, Jessica L. Billings, Eiman Saleh, Nadia Stefanova, Kevin J. Barnham, Paul A. Adlard · 2021 · Journal of Parkinson s Disease
  82. Ferroptosis in Alzheimer’s Disease: The Regulatory Role of Glial Cells
    Jingyi Xu, Rongjing Shen, Mengting Qian, Zhengjun Zhou, Bingqing Xie, Yong Qing Jiang, Yang Yu, Wei Dong · 2025 · Journal of Integrative Neuroscience
  83. Pramipexole restores depressed transmission in the ventral hippocampus following MPTP-lesion
    Javier Castro‐Hernández, Paul Anthony Adlard, David Isaac Finkelstein · 2017 · Scientific Reports
  84. Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation
    Alessandro Didonna, Ester Cantó, Hengameh Shams, Noriko Isobe, Chao Zhao, Stacy J. Caillier, Carlo Condello, Hana Yamate-Morgan, Seema Kaushalya Tiwari-Woodruff, Mohammad R. K. Mofrad et al. · 2019 · Journal of Autoimmunity
  85. Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation
    Anthony Papegaey, Sabiha Eddarkaoui, Vincent Deramecourt, Francisco-José Fernández-Gómez, Pierre Pantano, Hélène Obriot, Camille Machala, Vincent Anquetil, Agnès Camuzat, Alexis Brice et al. · 2016 · Acta Neuropathologica Communications
  86. Immunoreactivities for hepcidin, ferroportin, and hephaestin in astrocytes and choroid plexus epithelium of human brains
    Ken Yanase, Naoya Uemura, Yoichi Chiba, Ryuta Murakami, Ryuji Fujihara, Koichí Matsumoto, Gotaro Shirakami, Nobukazu Araki, Masaki Ueno · 2019 · Neuropathology
  87. An Introduction to Ultrasensitive Assays for Plasma Tau Detection
    Xulong Ding, Qing‐zhang Tuo, Peng Lei · 2021 · Journal of Alzheimer s Disease
  88. Direct comparison between 18F-Flortaucipir tau PET and quantitative susceptibility mapping in progressive supranuclear palsy
    Ryota Satoh, Farwa Ali, H. Botha, V. Lowe, K. Josephs, J. Whitwell · 2024 · NeuroImage
  89. Association of triglyceride-glucose index and delirium in patients with sepsis: a retrospective study
    Yipeng Fang, Aizhen Dou, Yuehao Shen, Tianyu Li, Haiying Liu, Yan Cui, Keliang Xie · 2024 · Lipids in Health and Disease
  90. Insulin Signaling in Alzheimer’s Disease: Association with Brain Insulin Resistance
    Monika Pliszka, Leszek Szablewski · 2026 · International Journal of Molecular Sciences
  91. Ginkgolides and Huperzine A for complementary treatment of Alzheimer's disease
    Cecilia Villegas, Rebeca Perez, Lyvia Lintzmaier Petiz, Talita Glaser, Henning Ulrich, Cristian Paz · 2022 · IUBMB Life
  92. COVID-19 and Alzheimer's Disease: Neuroinflammation, Oxidative Stress, Ferroptosis, and Mechanisms Involved
    Alicia Beatriz Pomilio, Arturo Alberto Vitale, Alberto Lazarowski · 2022 · Current Medicinal Chemistry
  93. Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models
    Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic, Christine Jolicoeur, Jenny Cai, Thérence Bois, Mélissa Desrosiers, Deniz Dalkara, Michel Cayouette · 2022 · Science Advances
  94. Alzheimer’s disease: an axonal injury disease?
    Dan Liang, Zhaohui Zhang · 2023 · Frontiers in Aging Neuroscience
  95. Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease: an update
    Bingyuan Zhou, Jing Li, Anqi Wu, Xuewei Wang, Le Cheng, Gaoshang Yang, Dahong Gao, Caifeng Zhu · 2025 · Frontiers in Aging Neuroscience
  96. Iron on trial: recasting the role of iron in neurodegeneration
    Scott Ayton, Caroline Moreau, David Devos, Ashley Ian Bush · 2025 · Brain
  97. Somatic Mutations and Alzheimer’s Disease
    Jocelyn Downey, Jacqueline C. K. Lam, Victor O. K. Li, Illana Gozes · 2022 · Journal of Alzheimer s Disease
  98. The old second messenger cAMP teams up with novel cell death mechanisms: potential translational therapeutical benefit for Alzheimer’s disease and Parkinson’s disease
    Tong Zhang, Minh Danh Anh Luu, Amalia M. Dolga, Ulrich L.M. Eisel, Martina Schmidt · 2023 · Frontiers in Physiology
  99. Ironing out tau's role in parkinsonism
    Jeannette N. Stankowski, Valina Lynn Dawson, Ted M. Dawson · 2012 · Nature Medicine
  100. Ex vivo three‐dimensional elemental imaging of mouse brain tissue block by laser‐induced breakdown spectroscopy
    Qingyu Lin, Shuai Wang, Yixiang Duan, Valery Victorovich Tuchin · 2021 · Journal of Biophotonics