Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

Sun, Zheng, Miller, Russell A, Patel, Rajesh T, Chen, Jie, Dhir, Ravindra, Wang, Hong, Zhang, Dongyan, Graham, Mark J +7 more·2012·Nature Medicine

Cited by (335)

Items 201–300 of 335

  1. The histone deacetylase inhibiting drug Entinostat induces lipid accumulation in differentiated HepaRG cells
    Abigail D.G. Nunn, T. Scopigno, Natalia Pediconi, Massimo Levrero, Henning Hagman, Jūris Kiškis, Annika M. K. Enejder · 2016 · Scientific Reports
  2. Tumour cells coerce host tissue to cancer spread
    Ilaria Malanchi · 2013 · BoneKEy Reports
  3. Serum iron and transferrin saturation variation are circadian regulated and linked to the harmonic circadian oscillations of erythropoiesis and hepatic Tfrc expression in mice
    Cavan Bennett, Anne Pettikiriarachchi, Alistair R. D. McLean, Rebecca Harding, Marnie E. Blewitt, Cyril Seillet, Sant‐Rayn Pasricha · 2024 · American Journal of Hematology
  4. Assessing Interactions Between Ghsr and Mc3r Reveals a Role for AgRP in the Expression of Food Anticipatory Activity in Male Mice
    Girardet Clemence, Maria Mavrikaki, Mark R. Southern, Roy G. Smith, Andrew A. Butler · 2014 · Endocrinology
  5. Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice
    Seung Jin Han, Sung‐E Choi, Sang‐A Yi, Jong Gab Jung, Ik‐Rak Jung, Maureen Shin, Seok Yun Kang, Hyunhee Oh, Hae Jin Kim, Dae Jung Kim et al. · 2016 · Scientific Reports
  6. Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis
    Nancy S. Magee, An Zou, Priyanka Ghosh, Forkan Ahamed, Don A. Delker, Yuxia Zhang · 2020 · Journal of Biological Chemistry
  7. Deleted in Breast Cancer 1 (DBC1) Protein Regulates Hepatic Gluconeogenesis
    Verónica Nin, Claudia C.S. Chini, Carlos Escande, Verena Kise Capellini, Eduardo N. Chini · 2014 · Journal of Biological Chemistry
  8. Inhibition of class I HDACs imprints adipogenesis toward oxidative and brown-like phenotype
    Alessandra Ferrari, Raffaella Longo, Carolina Peri, Lara Coppi, Donatella Caruso, Antonello Mai, Nico Mitro, Emma De Fabiani, Maurizio Crestani · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  9. Dietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs
    Wei He, Xinyu Liu, Ye Feng, Hongwei Ding, Haoyang Sun, Zhongyu Li, Baoming Shi · 2024 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
  10. Valproic acid administration exerts protective effects against stress-related anhedonia in rats
    Mina Goudarzi, Arezo Nahavandi, Soraya Mehrabi, Maryam Eslami, Ali Shahbazi, Mahmoud Barati · 2020 · Journal of Chemical Neuroanatomy
  11. The role of HDAC11 in obesity‐related metabolic disorders: A critical review
    Hong Yang, Ling‐Ling Chen, Qian Sun, Fangyao Yao, Muhammad Saeed, Chao Sun · 2021 · Journal of Cellular Physiology
  12. Exploring histone deacetylases in type 2 diabetes mellitus: pathophysiological insights and therapeutic avenues
    Kukkala Kiran Kumar, Elhadi Husein Aburawi, Miloš Ljubisavljević, Melvin Khee‐Shing Leow, Feng Xu, Suraiya Anjum Ansari, Bright Starling Emerald · 2024 · Clinical Epigenetics
  13. Dietary Oat β‐Glucan Alleviates High‐Fat Induced Insulin Resistance through Regulating Circadian Clock and Gut Microbiome
    Xingyu Wang, Gaoqi Ye, Zongwei Wang, Ziyuan Wang, Lingxiao Gong, Jing Wang, Jie Liu · 2024 · Molecular Nutrition & Food Research
  14. Epigenetics of Insulin Resistance: An Emerging Field in Translational Medicine
    Silvia Sookoian, Carlos Jose Pirola · 2013 · Current Diabetes Reports
  15. Zbtb7c is a critical gluconeogenic transcription factor that induces glucose-6-phosphatase and phosphoenylpyruvate carboxykinase 1 genes expression during mice fasting
    Won‐Il Choi, Jae-Hyeon Yoon, Ji-Yang Song, Bu‐Nam Jeon, Joo-Man Park, Dong‐In Koh, Yong‐Ho Ahn, Kyung‐Sup Kim, In Kyu Lee, Man‐Wook Hur · 2019 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  16. Non-alcoholic fatty liver disease: molecular and cellular interplays of the lipid metabolism in a steatotic liver
    Letícia Ferreira Ramos, Caio Mateus da Silva, Camila Cristiane Pansa, Karen C. M. Moraes · 2020 · Expert Review of Gastroenterology & Hepatology
  17. Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1
    Yang Cao, Lingyi Tang, Kang Du, Kitt D. Paraiso, Qiushi Sun, Zhengxia Liu, Xiaolong Ye, Yuan Fang, Fang Yuan, Hank Chen et al. · 2021 · JCI Insight
  18. Decoding liver injury: A regulatory role for histone modifications
    Wenfang Tian, Yong Xu · 2015 · The International Journal of Biochemistry & Cell Biology
  19. HDAC5 Inhibits Hepatic Lipogenic Genes Expression by Attenuating the Transcriptional Activity of Liver X Receptor
    Hai-Yan Jia, Quanzhong Li, Li-Fang Lv · 2016 · Cellular Physiology and Biochemistry
  20. Genistein and exercise treatment reduced NASH related HDAC3, IL-13 and MMP-12 expressions in ovariectomized rats fed with high fat high fructose diet
    Namthip Witayavanitkul, Duangporn Werawatganon, Maneerat Chayanupatkul, Naruemon Klaikeaw, Prasong Siriviriyakul · 2021 · Journal of Traditional and Complementary Medicine
  21. Alteration of NCoR Corepressor Splicing in Mice Causes Increased Body Weight and Hepatosteatosis without Glucose Intolerance
    Michael L. Goodson, Briana M. Young, Chelsea A. Snyder, Amy C. Schroeder, Martin L. Privalsky · 2014 · Molecular and Cellular Biology
  22. Muscle-Specific Deletion of Comparative Gene Identification-58 (CGI-58) Causes Muscle Steatosis but Improves Insulin Sensitivity in Male Mice
    Ping Xie, Anil K.G. Kadegowda, Yinyan Ma, Feng Guo, Xianlin Han, Miao Wang, Leanne Groban, Bingzhong Xue, Hang Shi, Hui‐Hua Li et al. · 2015 · Endocrinology
  23. Is oxidative stress involved in the hepatic inflammatory response to apical periodontitis? A comparative study in normal and hyperlipidaemic rat
    Suli Xiao, Huaxiang Lei, Pingping Li, Dianfu Ma, Shuai Chen, Xiaojing Huang · 2023 · International Endodontic Journal
  24. Novel mechanism for zinc inducing hepatic lipolysis via the HDAC3-mediated deacetylation of β-catenin at lysine 311
    Yi-Chuang Xu, Hua Zheng, Christer Högstrand, Xiao-Ying Tan, Tao Zhao, Yu–Feng Song, Xiaolei Wei, Li‐Xiang Wu, Zhi Luo · 2023 · The Journal of Nutritional Biochemistry
  25. The Roles of White Adipose Tissue and Liver NADPH in Dietary Restriction-Induced Longevity
    Leah E. Jamerson, Patrick C. Bradshaw · 2024 · Antioxidants
  26. Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis
    Nancy S. Magee, An Zou, Priyanka Ghosh, Forkan Ahamed, Don A. Delker, Yuxia Zhang · 2019 · Journal of Biological Chemistry
  27. Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation
    Hongxue Li, Qian Xu, Chengye Xu, Yuxin Hu, Xingyang Yu, Kangqi Zhao, Ming‐Qing Li, Meng Li, Junfang Xu, Hongyu Kuang · 2021 · Frontiers in Pharmacology
  28. New Insights into the Connection Between Histone Deacetylases, Cell Metabolism, and Cancer
    Ferdinando Chiaradonna, Claudia Cirulli, Roberta Palorini, Giuseppina Votta, Lilia Alberghina · 2014 · Antioxidants and Redox Signaling
  29. Nuclear receptor corepressors non-canonically drive glucocorticoid receptor-dependent activation of hepatic gluconeogenesis
    Amy K. Hauck, Rashid Mehmood, Bryce J. Carpenter, Maxwell Frankfurter, Michael C. Tackenberg, Shin‐ichi Inoue, M Krieg, Fathima N. Cassim Bawa, Mohit K. Midha, Delaine M. Zundell et al. · 2024 · Nature Metabolism
  30. Epigenetics
    Rajan Jain, Jonathan A. Epstein · 2024 · Advances in experimental medicine and biology
  31. Is periodontitis triggering an inflammatory response in the liver, and does this reaction entail oxidative stress?
    Kaviyarasi Renu, Abilash Valsala Gopalakrishnan, Harishkumar Madhyastha · 2024 · Odontology
  32. Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction
    Meghan E. McGee‐Lawrence, Thomas A. White, Nathan K. LeBrasseur, Jennifer J. Westendorf · 2015 · Molecular and Cellular Endocrinology
  33. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle
    Yingyun Gong, Rui Cao, Guolian Ding, Sungguan Hong, Wenjun Zhou, Wenyun Lu, Manashree Damle, Bin Fang, Chuhan Wang, Justin Qian et al. · 2017 · Molecular and Cellular Endocrinology
  34. Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity
    Meghan E. McGee‐Lawrence, Jessica L. Pierce, Kanglun Yu, Natasha R. Culpepper, Elizabeth W. Bradley, Jennifer J. Westendorf · 2017 · Journal of Cellular Physiology
  35. Comparative gene identification-58/α/β hydrolase domain 5
    Kathrin A. Zierler, Rudolf Zechner, Guenter Haemmerle · 2014 · Current Opinion in Lipidology
  36. Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease
    Xiaolong Wei, Megan A. Murphy, Nihal A. Reddy, Yi Hao, Taylor G. Eggertsen, Jeffrey J. Saucerman, Irina M. Bochkis · 2022 · Genome Research
  37. HDAC in obesity: A critical insight
    Nijhawan, Priya, Behl, Tapan, Khullar, Gaurav, Pal, Giridhari, Kandhwal, Mimansa, Goyal, Amit · 2020 · Obesity Medicine
  38. Role of the histone deacetylase family in lipid metabolism: Structural specificity and functional diversity
    Yunxia Li, Qi Han, Yuxin Liu, Jie Lin Yin, Jie Ma · 2024 · Pharmacological Research
  39. Nonalcoholic Fatty Liver Disease (NAFLD) Name Change: Requiem or Reveille?
    Shivaram P. Singh, Prajna Anirvan, Reshu Khandelwal, Sanjaya Kumar Satapathy · 2021 · Journal of Clinical and Translational Hepatology
  40. Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue
    Hannah J. Richter, Amy K. Hauck, Kirill Batmanov, Shin‐ichi Inoue, Bethany Nahri So, Mindy Kim, Matthew J. Emmett, Ronald Cohen, Mitchell A. Lazar · 2022 · Proceedings of the National Academy of Sciences
  41. The Polycomb protein, Bmi1, regulates insulin sensitivity
    Corey E. Cannon, Paul M. Titchenell, David Groff, Abdelfattah El Ouaamari, Rohit Kulkarni, Morris J. Birnbaum, Doris A. Stoffers · 2014 · Molecular Metabolism
  42. The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice
    Sylvie Casteras, Aya Abdul-Wahed, Maud Soty, Fanny Vulin, Hervé Guillou, Maria B. Campaña, Hervé Le Stunff, Luciano Pirola, Fabienne Rajas, Gilles Mithieux et al. · 2016 · Diabetologia
  43. Protective effect of exercise on metabolic dysfunction‑associated fatty liver disease: Potential epigenetic mechanisms (Review)
    Yanhua Zhang, Yuqin Wei, Huan Liu, Yanju Guo · 2025 · International Journal of Molecular Medicine
  44. Role of histone deacetylase on nonalcoholic fatty liver disease
    Shifeng Fu, Meihong Yu, Yuyong Tan, Deliang Liu · 2020 · Expert Review of Gastroenterology & Hepatology
  45. Rev-erbs: Integrating Metabolism Around the Clock
    Mitchell A. Lazar · 2016 · Research and perspectives in endocrine interactions
  46. Deacetylase‐dependent and ‐independent role of HDAC3 in cardiomyopathy
    Jieyu Ren, Qun Zeng, Hongmei Wu, Xuewen Liu, María Clara Guida, Wen Huang, Yiyuan Zhai, Junjie Li, Karen A. Ocorr, Rolf Bodmer et al. · 2023 · Journal of Cellular Physiology
  47. Comparison of expression levels of fourteen genes involved in the lipid and energy metabolism in two pig breeds
    Martina Zappaterra, Silvia Braglia, Mila Bigi, Paolo Zambonelli, R. Davoli · 2015 · Livestock Science
  48. Circadian Clock Regulation of Hepatic Energy Metabolism Regulatory Circuits
    Louise Hunter, David William Ray · 2019 · Biology
  49. Epigenetic Alterations in Alzheimer’s Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems
    Alosh Greeny, Ayushi Nair, Prashant Sadanandan, Sairaj Satarker, Ademola C. Famurewa, Madhavan Nampoothiri · 2024 · Biology
  50. Effects of earthworm extract on the lipid profile and fatty liver induced by a high-fat diet in guinea pigs
    Zhenhan Deng, Shanshan Gao, Yunfei An, Yong Zhi Huang, Haifeng Liu, Weimin Zhu, Wei Lu, Miao He, Wenqing Xie, Dengjie Yu et al. · 2021 · Annals of Translational Medicine
  51. Inside anticancer therapy resistance and metastasis. Focus on CD36
    Ioana Maria Lambrescu, Gisela F. Gaina, Laura Cristina Ceafalan, Mihail Eugen Hinescu · 2024 · Journal of Cancer
  52. Dieckol-Attenuated High-Fat Diet Induced Muscle Atrophy by Modulating Muscular Deposition of Lipid Droplets
    Kyung-A Byun, Seyeon Oh, Myeongjoo Son, Seung Eon Oh, Chul-Hyun Park, Kuk Hui Son, Kyunghee Byun · 2021 · Nutrients
  53. Hdac3-deficiency increases senescence-associated distention of satellite DNA and telomere-associated foci in osteoprogenitor cells
    Dongwook Yeo, Elizabeth L Zars Fisher, Sundeep Khosla, Joshua N. Farr, Jennifer J. Westendorf · 2024 · Journal of Bone and Mineral Research
  54. Role of Protein Lysine Acetylation in the Pathogenesis and Treatment of Obesity and Metabolic Syndrome
    Zhaopeng Li, Yancheng Song, Li Zhao, Shuguang Liu, Song Yi, Zhuoli Zhang, Tao Yu, Yu Li · 2025 · Current Obesity Reports
  55. In Vivo Two-Photon Imaging Analysis of Dynamic Degradation of Hepatic Lipid Droplets in MS-275-Treated Mouse Liver
    Chang-Gun Lee, Soojin Lee, Seokho Park, Sung‐E Choi, Minwoo Song, Hyo Won Lee, Hae Jin Kim, YUP Y. KANG, Kwan Woo Lee, Hwan Myung Kim et al. · 2022 · International Journal of Molecular Sciences
  56. Effect of high-fat diet prior to pregnancy on hepatic gene expression and histology in mouse offspring
    H. Hori, M. Umezawa, M. Uchiyama, R. Niki, S. Yanagita, K. Takeda · 2014 · Journal of Perinatal Medicine
  57. Genome-wide analysis of DNA methylation identifies novel differentially methylated regions associated with lipid accumulation improved by ethanol extracts of Allium tubersosum and Capsella bursa-pastoris in a cell model
    Moonju Hong, Jin‐Taek Hwang, Eun Ju Shin, Haeng Jeon Hur, Keunsoo Kang, Hyo‐Kyoung Choi, Min‐Yu Chung, Sangwon Chung, Mi Jeong Sung, Jae‐Ho Park · 2019 · PLoS ONE
  58. HDAC3 regulates senescence and lineage specificity in non-small cell lung cancer
    Lillian J. Eichner, Stephanie D. Curtis, Sonja N. Brun, Joshua T. Baumgart, Debbie S. Ross, Tammy J. Rymoff, Reuben J. Shaw · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  59. HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes
    Juan Ren, Dongmin Li, Yue Li, Xi Lan, Jianhuai Zheng, Xuan Wang, Jie Ma, Shemin Lu · 2013 · Molecular and Cellular Endocrinology
  60. Crosstalk between Epigenetics and Autophagy in Metabolic Dysfunction-Associated Steatotic Liver Disease
    Irfana Zahoor, Gh Jeelani Mir, Nazir Ahmad Lone, Nissar Ul Ashraf · 2025 · Journal of Obesity & Metabolic Syndrome
  61. Lipid metabolism indicators provide tools for the diagnosis of non-alcoholic fatty liver disease: results of a nationwide survey
    Yongxin Wang, Chang Fu, Hengwei Jin, Yibo Yang, Xiaocong Li, Kai Liu · 2025 · Frontiers in Endocrinology
  62. ILDR2 has a negligible role in hepatic steatosis
    Elizabeth J. Millings, Maria Caterina De Rosa, Sarah E. Fleet, Kazuhisa Watanabe, Richard N. Rausch, Dieter M. Egli, Gen Li, Charles A. LeDuc, Yiying Zhang, Stuart G. Fischer et al. · 2018 · PLoS ONE
  63. Mitochondrial lipid metabolism in metastatic breast cancer
    Bhuban Ruidas · 2024 · Mitochondrial Communications
  64. Environmental regulation of metabolism through the circadian clock
    Quetzalcóatl Escalante‐Covarrubias, Lorena Aguilar‐Arnal · 2018 · Current Opinion in Toxicology
  65. Overlapping and non-overlapping roles of the class-I histone deacetylase-1 corepressors LET-418, SIN-3, and SPR-1 in Caenorhabditis elegans embryonic development
    Yukihiko Kubota, Yuto Ohnishi, Tasuku Hamasaki, Gen Yasui, Natsumi Ota, Hiromu Kitagawa, Arashi Esaki, Muhamad Fahmi, Masahiro Ito · 2021 · Genes & Genomics
  66. Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats
    Weidong Li, Xia Jin-rong, Yan‐Shu Lian · 2019 · Molecular Medicine Reports
  67. Interference with the HNF4-dependent gene regulatory network diminishes endoplasmic reticulum stress in hepatocytes
    Anit Shah, Ian Huck, Kaylia Mekelda Duncan, Erica R. Gansemer, Kaihua Liu, Reed C. Adajar, Udayan M. Apte, Mark A. Stamnes, D. Thomas Rutkowski · 2023 · Hepatology Communications
  68. Sucralose and stevia consumption leads to intergenerational alterations in body weight and intestinal expression of histone deacetylase 3
    Francisca Concha Celume, Francisco Pérez‐Bravo, Martín Gotteland · 2024 · Nutrition
  69. p110α Hot Spot Mutations E545K and H1047R Exert Metabolic Reprogramming Independently of p110α Kinase Activity
    Aditi Chaudhari, Daniel Krumlinde, Annika Lundqvist, Levent M. Akyürek, Sashidhar Bandaru, Kristina Skålén, Marcus Ståhlman, Jan Borén, Yvonne Wettergren, Katarina Ejeskär et al. · 2015 · Molecular and Cellular Biology
  70. Valproic acid targets IDH1 mutants through alteration of lipid metabolism
    Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria Graciela Castro et al. · 2024 · npj Metabolic Health and Disease
  71. Immune Surveillance by Myeloid-Derived Suppressor Cells in Liver Diseases
    Rashi Sehgal, Navkiran Kaur, Gayatri Ramakrishna, Nirupma Trehanpati · 2021 · Digestive Diseases
  72. Low-protein diet during gestation and lactation increases hepatic lipid accumulation through autophagy and histone deacetylase
    Huan Wang, Guanying Bianca Xu, Diego Hernández‐Saavedra, Hong Chen, Yuan‐Xiang Pan · 2020 · American Journal of Physiology-Endocrinology and Metabolism
  73. Nuclear receptor coregulator interactions: beyond the switch
    Fathima N. Cassim Bawa, Mitchell A. Lazar · 2025 · Genes & Development
  74. Downregulation of HDAC9 Alleviates Autophagy Dysfunction by Inducing Acetylation of ATG4B in Metabolic Dysfunction‐Associated Steatotic Liver Disease
    Xiao‐Han Ma, G. Liu, Le Liu, Zhuli Dou, Xue Mei He, Xi Chen · 2025 · The FASEB Journal
  75. Epigenetic repurposing of carbohydrate metabolic inhibitors for insulin resistance: targeting DNMT1 and HDAC3 for β-cell restoration
    Muhammad Javid Iqbal, Luis Antonio Salazar · 2025 · Frontiers in Epigenetics and Epigenomics
  76. The Potential of Epigenetic Compounds in Treating Diabetes
    Steven G. Gray · 2018 · Elsevier eBooks
  77. A class I histone deacetylase HDA-2 is essential for embryonic development and size regulation of fertilized eggs in Caenorhabditis elegans
    Takuma Unno, Hisashi Takatsuka, Yuto Ohnishi, Masahiro Ito, Yukihiko Kubota · 2021 · Genes & Genomics
  78. HDAC3 Controls Liver Homeostasis More by Facilitating Deoxyribonucleic Acid Damage Repair than by Regulating Transcription in Hepatocytes
    Qing Tao, Hongjie Ji, Yongjie Zhou, Yuke Shu, Yuwei Chen, Mingyang Shao, Zhenru Wu, Menglin Chen, Tao Lv, Yujun Shi · 2023 · Laboratory Investigation
  79. Polymorphisms Related to Iron Homeostasis Associate with Liver Disease in Chronic Hepatitis C
    Anna Wróblewska, Anna Woziwodzka, Magda Rybicka, Krzysztof Piotr Bielawski, Katarzyna Sikorska · 2023 · Viruses
  80. Study on the Role and Mechanism of HDAC6 in Cd-Induced Inflammation and Fibrosis in Mice Liver
    Fan Guo, Ningfei Lei, Rongshuang Huang, Zhuo Huang, Ping Zhao, XU Xiang-ning, Weizhen Zhang · 2023 · Biology Bulletin
  81. Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism
    Michael L. Goodson, Trina A. Knotts, Elsie Lin Campbell, Chelsea A. Snyder, Briana M. Young, Martin L. Privalsky · 2020 · PLoS ONE
  82. Effects of Diets with Different Energy Levels at Cold Temperatures on Gut Microbiota and Metabolic State in Growing–Finishing Pigs
    Wei He, Guangdong Bai, Teng Teng, Baoming Shi, Li Wang · 2025 · Microorganisms
  83. Association between C-reactive protein-triglyceride glucose index and NAFLD in US adults: A nationally cross-sectional study using NHANES 2017-2020 data
    Yuanyuan Chen, Jinmin Cao, Huihui Chen, Bing You Yang, Jun Chen, Chuantie Chen · 2025 · Medicine
  84. Metformin Increased Histone Deacetylases 1, 3, and 8 Expressions as Epigenetic Regulators in Type 2 Diabetic Patients
    Amin Izadi, Azam Zarourati, Sohrab Boozarpour, Mohsen Ghalandar, Mina Lashkarboloki, Madjid Momeni‐Moghaddam, Masoud Fahimi · 2025 · Reports of Biochemistry and Molecular Biology
  85. Molecular mechanisms and pathogenesis of MASH
    Suchira Gallage, Olivier Govaere, Quentin Mark Anstee, Gerald I. Shulman, Frank Tacke, Mathias F Heikenwälder · 2026 · Nature
  86. HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity
    Franciéle Romero Machado, Silvana Peterini Boeira, Vandreza Cardoso Bortolotto, Stífani Machado Araújo, Márcia Rósula Poetini, Cristini Escobar Viana, Marina Prigol, Leandro Cattelan Souza, Marcelo Gomes de Gomes · 2023 · Pharmacological Reports
  87. The somatic genome of Eptatretus okinoseanus reveals the adaptation to deep-sea oligotrophic environment
    Mengke Shi, Qi Li, Yong Wang, Lisheng He · 2024 · BMC Genomics
  88. Histone Deacetylase HDAC8 and Insulin Resistance
    Vincent Wai‐Sun Wong, Myth T.S. Mok, Alfred S.L. Cheng · 2017 · Springer eBooks
  89. iTRAQ‐ and LC–MS/MS‐based quantitative proteomics reveals Pqlc2 as a potential regulator of hepatic glucose metabolism and insulin signalling pathway during fasting
    Di‐Yang Sun, Jiang‐Tao Fu, Guoqiang Li, Wen‐Jie Zhang, Fei‐Yan Zeng, Jie Tong, Chao‐Yu Miao, Dongjie Li, Pei Wang · 2020 · Clinical and Experimental Pharmacology and Physiology
  90. TCF7 is not essential for glucose homeostasis in mice
    Kiran Deep Kaur, Chi Kin Wong, Laurie L. Baggio, Jacqueline Leah Beaudry, Shai Fuchs, Brandon L. Panaro, Dianne Matthews, Xiemin Cao, Daniel J. Drucker · 2021 · Molecular Metabolism
  91. HDAC11 Deficiency Prevents High-Fat Diet-Induced Obesity and Metabolic Syndrome
    Lei Sun, Caralina Marín de Evsikova, Ka Bian, Alexandra Achille, Elphine Telles, Edward Seto · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  92. Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and lipid droplet regulation
    Melissa A. Roberts, Kirandeep K. Deol, Mike Lange, Dara E. Leto, Alyssa J. Mathiowetz, Julian Stevenson, Sayed Hadi Hashemi, David W. Morgens, Emilee Easter, Kartoosh Heydari et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes
    Anit Shah, Ian Huck, Kaylia Mekelda Duncan, Erica R. Gansemer, Udayan M. Apte, Mark A. Stamnes, D. Thomas Rutkowski · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Serum iron variation is circadian-regulated and linked to the harmonic circadian oscillations of erythropoiesis and hepatic Tfrc expression in mice
    Cavan Bennett, Anne Pettikiriarachchi, Alistair R. D. McLean, Rebecca Harding, Marnie E. Blewitt, Cyril Seillet, Sant‐Rayn Pasricha · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  95. Developmental Programming of Nonalcoholic Fatty Liver Disease (NAFLD)
    Kimberley D. Bruce, Felino Ramon A. Cagampang · 2016 · Springer eBooks
  96. What Do Higher Alanine Aminotransferase Levels Mean in Premature Ovarian Insufficiency?
    Weina Wang, Xi Cheng, Jinhan Yao, Hanchun Xue, Chenglu Li, Xia Wang, You Zhang, Siyi Chen, Yuquan Zhang · 2023 · Reproductive Sciences
  97. The modification effect of fasting blood glucose level on the associations between short-term ambient air pollution and blood lipids
    Yi Zhang, Pai Zheng, Jiaqi Shi, Ying Ma, Zhangjian Chen, Tiancheng Wang, Guang Jia · 2023 · International Journal of Environmental Health Research
  98. Atg2 coordinates microbial metabolite signaling and epigenetic remodeling to maintain intestinal lipid homeostasis in Drosophila
    Ping Wang, Xinran Li, Jiangong Zhang, Jiewei Wang, Li Hua Jin · 2026 · Microbiome
  99. The histone deacetylase family in health and disease
    Ri Wen, Yuhang Yang, Tao Zhang, Sen-Yu Zhang, Xin-Ru Yang, Li-Ying Zhang, Peng-Hui Hao, Yue Zheng, Yang Ni, Tie‐Ning Zhang · 2026 · Signal Transduction and Targeted Therapy
  100. Chromatin Signaling in Aging and Cellular Senescence
    Florence Couteau, Frédérick A. Mallette · 2016 · Elsevier eBooks