MDM4 is a key therapeutic target in cutaneous melanoma

Gembarska, Agnieszka, Luciani, Flavie, Fedele, Clare, Russell, Elisabeth A, Dewaele, Michael, Villar, Stéphanie, Zwolinska, Aleksandra, Haupt, Sue +14 more·2012·Nature Medicine

DOI 10.1038/nm.2863

Cited by (330)

Items 201–300 of 330

Mdm2 and MdmX Involvement in Human Cancer
Steven J. Berberich · 2014 · Sub-cellular biochemistry/Subcellular biochemistry
The Future of Molecular Analysis in Melanoma: Diagnostics to Direct Molecularly Targeted Therapy
Hugo Akabane, R. Sullivan · 2016 · American Journal of Clinical Dermatology
MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling
Qingling Huang, Lihong Chen, E. Schönbrunn, Jiandong Chen · 2020 · The EMBO Journal
Investigating intrinsic radiosensitivity biomarkers to peptide receptor radionuclide therapy with [177Lu]Lu-DOTATATE in a panel of cancer cell lines
Wendy Delbart, Ghanem Ghanem, Ioannis Karfis, Patrick Flamen, Zéna Wimana · 2021 · Nuclear Medicine and Biology
Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching
Jasper Wouters, Zeynep Kalender Atak, Liesbeth Minnoye, Katina I. Spanier, Maxime De Waegeneer, Carmen Bravo González‐Blas, David Mauduit, Kristofer Davie, Gert J. Hulselmans, Ahmad Najem et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Cis-topic modelling of single-cell epigenomes
C. González-Blas, Liesbeth Minnoye, Dafni Papasokrati, S. Aibar, G. Hulselmans, Valerie Christiaens, K. Davie, J. Wouters, S. Aerts · 2018 · bioRxiv
Strategies for p53 Reactivation in Human Sarcoma
Ted R. Hupp, Richard L. Hayward, Borek Vojtesek · 2012 · Cancer Cell
Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways
Zhenhe Zhang, Miles D. Freeman, Yiqiang Zhang, Danny El‐Nachef, George Davenport, Allison Lesher Williams, William Robb MacLellan · 2023 · PLoS ONE
Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Timothy Myers, Tongwu Zhang, Raj Chari, Erping Long, Thomas Rehling et al. · 2025 · The American Journal of Human Genetics
Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
Wenjun Fan, Hester Liu, Gregory C. Stachelek, Asma Begum, Catherine E. Davis, Tony E Dorado, G. Ernst, William C. Reinhold, Busra Ozbek, Q. Zheng et al. · 2025 · Cell Chemical Biology
Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status
Javier Octavio Mejía-Hernández, Dinesh Raghu, Franco Caramia, Nicholas James Clemons, Kenji Mark Fujihara, Thomas Riseborough, Amina F.A.S. Teunisse, Aart G. Jochemsen, Lars Abrahmsén, Giovanni Blandino et al. · 2022 · Cancers
Roles and mechanisms of aberrant alternative splicing in melanoma — implications for targeted therapy and immunotherapy resistance
Wanxian Chen, Deyi Geng, Jiasheng Chen, Xiaosha Han, Qihu Xie, Genghong Guo, Xuefen Chen, Wancong Zhang, Shijie Tang, Xiaoping Zhong · 2024 · Cancer Cell International
Designing dual inhibitors of Mdm2/MdmX: Unexpected coupling of water with gatekeeper Y100/99
Xiong An Lee, Chandra Shekhar Verma, Adelene Y. L. Sim · 2017 · Proteins Structure Function and Bioinformatics
CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3
Henri Montaudié, Laura Sormani, Bérengère Dadone‐Montaudié, M. Heim, Nathalie Cardot‐Leccia, Meri K. Tulić, Guillaume E. Béranger, Anne-Sophie Gay, Delphine Debayle, Yann Chéli et al. · 2021 · Journal of Investigative Dermatology
An enhanced functional interrogation/manipulation of intracellular signaling pathways with the peptide ‘stapling’ technology
Yuan He, David X. W. Chen, Weiping Zheng · 2015 · Oncogene
Macrocyclic α-Helical Peptide Drug Discovery
Tomi K. Sawyer, Vincent Guerlavais, Krzysztof Darłak, Eric Feyfant · 2014 · Royal Society of Chemistry eBooks
Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells
Maria Proto, Donatella Fiore, Giovanni Forte, Paola Cuozzo, Anna Ramunno, Caterina Fattorusso, Patrizia Gazzerro, Maria Carmela Pascale, Silvia Franceschelli · 2019 · Investigational New Drugs
Targeting p53 activation: Recent therapeutic advances in cancer and diabetic macular edema
Zhiyi Wang, Shijie Zhang, Irakoze Loïca Mélita, Yujun Zhao · 2025 · European Journal of Medicinal Chemistry
Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy
Jie Dai, Xue Li Bai, Xuan Gao, Lirui Tang, Yu Chen, Linzi Sun, Xiaoting Wei, Caili Li, Zhonghui Qi, Yan Kong et al. · 2023 · Journal for ImmunoTherapy of Cancer
Targeting the MDM2 ‐ MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi et al. · 2025 · Molecular Oncology
MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A
Abdullah Salem S. Alatawi, Soon Jye Kho, Michael P. Markey · 2021 · Journal of Skin Cancer
The alternative translated MDMXp60isoform regulates MDM2 activity
Anne-Sophie Tournillon, Ignacio López, Laurence Malbert-Colas, Nadia Naski, Vanesa Olivares‐Illana, Robin Fåhræus · 2015 · Cell Cycle
MDM4 expression in fibrolamellar hepatocellular carcinoma
Anju Karki, Juan Putra, Stephanie M. Kim, Michael P. LaQuaglia, Antonio R. Pérez‐Atayde, Ghazaleh Sadri‐Vakili, Khashayar Vakili · 2019 · Oncology Reports
Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4
Rossella Lucà, Giorgia di Blasio, Daniela Gallo, Valentina Monteleone, Isabella Manni, Laura Fici, Marianna Buttarelli, Germana Ciolli, Marsha Pellegrino, Emanuela Teveroni et al. · 2019 · Cancers
Cell Senescence and the Genetics of Melanoma Development
Sophie M. Constantinou, Dorothy C. Bennett · 2024 · Genes Chromosomes and Cancer
Animal Models of Melanoma
Zackie Aktary, Martin McMahon, Lionel Larue · 2017 · Springer eBooks
MDM2/P53 Inhibitors as Sensitizing Agents for Cancer Chemotherapy
Yan Yu Zhu, Herui Wang, Asha Thuraisamy · 2019 · Elsevier eBooks
A concise review on MDM2 inhibitors and recent progress in radiopharmaceutical development for imaging MDM2 expression in tumors with PET or SPECT
Atchimnaidu Siriki, Graham Ragland, Janardhan Vasireddy, Satish K. Chitneni · 2025 · Bioorganic & Medicinal Chemistry Letters
Recent Developments in Targeting the Cell Cycle in Melanoma
Christie Hung, Trang Thi Thu Nguyen, Poulikos I. Poulikakos, David Polsky · 2025 · Cancers
Development of a novel immunoassay to detect interactions with the transactivation domain of p53: application to screening of new drugs
Yufeng Xiong, Yingsong Wu, Shuhong Luo, Yang Gao, Yujing Xiong, Daxiang Chen, Hao Deng, Wenbo Hao, Tiancai Liu, Ming Li · 2017 · Scientific Reports
Association of MDM2 Overexpression in Ameloblastomas with MDM2 Amplification and BRAFV600E Expression
Konstantinos I. Tosios, Eleni‐Marina Kalogirou, Ioannis George Koutlas · 2024 · International Journal of Molecular Sciences
p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis
Mehrnoosh Tashakori, Yun Zhang, Shunbin Xiong, Mingjian James You, Guillermina Lozano · 2015 · Molecular Cancer Research
The fate of murine double minute X (MdmX) is dictated by distinct signaling pathways through murine double minute 2 (Mdm2)
Paula M. Hauck, Eric R. Wolf, David J. Olivos, Ciarán P. McAtarsney, Lindsey D. Mayo · 2017 · Oncotarget
Copy number variation in archival melanoma biopsies versus benign melanocytic lesions
Ahmed Mahas, Keerti Potluri, Michael N. Kent, Sameep Naik, Michael P. Markey · 2016 · Cancer Biomarkers
Dual Targeting of MDM4 and FTH1 by MMRi71 for Induced Protein Degradation and p53-Independent Apoptosis in Leukemia Cells
Rati Lama, Samuel L. Galster, Chao Xu, Luke W. Davison, Sherry R. Chemler, Xinjiang Wang · 2022 · Molecules
MLKL deficiency in BrafV600EPten−/− melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice
Sofie Martens, Nozomi Takahashi, Gillian Blancke, Niels Vandamme, Hanne Verschuere, Tatyana Divert, Marnik Vuylsteke, Geert Berx, Peter Vandenabeele · 2022 · Cell Death and Disease
Derivation and Use of Cell Lines from Mouse Models of Melanoma
Zackie Aktary, Jérémy H. Raymond, Marie Pouteaux, Véronique Delmas, Valérie Petit, Lionel Larue · 2023 · Journal of Investigative Dermatology
Emerging Role of the p53 Pathway in Modulating NK Cell–Mediated Immunity
Yu‐Chi Chen, Christopher G. Bazewicz, Saketh Sriram Dinavahi, Nicholas D. Huntington, Todd D. Schell, Gavin P. Robertson · 2024 · Molecular Cancer Therapeutics
Role of Sex in the Therapeutic Targeting of p53 Circuitry
Francesca Mancini, Ludovica Giorgini, Emanuela Teveroni, Alfredo Pontecorvi, Fabiola Moretti · 2021 · Frontiers in Oncology
Disulfiram enhances chemotherapeutic effects of doxorubicin liposomes against human hepatocellular carcinoma via activating ROS-induced cell stress response pathways
Hai Lin, Fengjie Sun, Tingting Li, Yihan Zhang, Xiaochun Guo, Ming Li, Min Liang, Xinke Zhou, Zhiyuan Fang · 2022 · Cancer Chemotherapy and Pharmacology
Ezetimibe Anticancer Activity via the p53/Mdm2 Pathway
Charmy Twala, Sibusiso Tebogo Malindisa, Chamoné Munnik, Selisha Ann Sooklal, Monde McMillan Ntwasa · 2025 · Biomedicines
Novel insights about the MDM2/MDM4 heterodimer
Fabiola Moretti · 2015 · Molecular & Cellular Oncology
The role of miRNAs in MDMX‐p53 interplay
Dehua Yu, Zhiyuan Xu, Xiangdong Cheng, Jiang‐Jiang Qin · 2021 · Journal of Evidence-Based Medicine
Transcriptome-Wide Association Study Reveals New Molecular Interactions Associated with Melanoma Pathogenesis
Mohamed N. Saad, Mohamed Hamed · 2024 · Cancers
Protein–Protein Interaction Inhibitors in Cancer
Ian Robert Hardcastle · 2016 · Elsevier eBooks
MDMX under stress: the MDMX-MDM2 complex as stress signals hub
Anna de Polo, Verunika Vivekanandan, John B. Little, Zhi-Min Yuan · 2016 · Translational Cancer Research
MageC2 protein is upregulated by oncogenic activation of MAPK pathway and causes impairment of the p53 transactivation function
Franco Andrés Pascucci, María Fátima Ladelfa, María Fernanda Toledo, Micaela Carolina Escalada, Melisa Suberbordes, Martín Monte · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
MDM4 polymorphisms associated with the risk but not the prognosis of esophageal cancer in Cixian high‐incidence region from northern China
Rong‐Miao Zhou, Yan Li, Na Wang, Chao-Xu Niu, Xi Huang, Shiru Cao, Xiangran Huo · 2022 · Asia-Pacific Journal of Clinical Oncology
1205Lu Human Metastatic Melanoma Cells, not Human!
Hareesh B. Nair · 2013 · Journal of Cancer Science & Therapy
Cellular, Structural Basis, and Recent Progress for Targeting Murine Double Minute X (MDMX) in Tumors
Qikun Yin, Yuemiao Hu, Zhiwen Dong, Jing Lu, Hongbo Wang · 2024 · Journal of Medicinal Chemistry
MAGE-I proteins and cancer-pathways: A bidirectional relationship
Franco Andrés Pascucci, Micaela Carolina Escalada, Melisa Suberbordes, Candela Vidal, María Fátima Ladelfa, Martín Monte · 2022 · Biochimie
Oncogene-directed small molecule inhibitors for the treatment of cutaneous melanoma.
Philip J Eliades, K. Flaherty, H. Tsao · 2015 · Melanoma Management
p53 Regulation by TRP2 Is Not Pervasive in Melanoma
Roland Houben, Corinna P. Schmid, Melissa Maier, Marion Wobser, Stephanie Motschenbacher, Jürgen Christian Becker, Claudia S. Vetter‐Kauczok, Gerhard H. Weyandt, Sonja Hesbacher, Sebastian Haferkamp · 2014 · PLoS ONE
Mechano growth factor E peptide inhibits invasion of melanoma cells and up-regulates CHOP expression via endoplasmic reticulum stress
Jianhua He, Lili Dong, Kang Xu, Yuna Qian, Chunli Wang, Yongqiang Sha, Juila Li Zhong, Wanqian Liu, Yonggang Lv, Yang Song et al. · 2017 · Biotechnology Letters
Targeting the MDM2–p53 Protein–Protein Interaction
Ian Robert Hardcastle · 2014 · Elsevier eBooks
Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning
Z. Atak, I. I. Taskiran, Christopher C. Flerin, D. Mauduit, Liesbeth Minnoye, Gert Hulsemans, Valerie Christiaens, G. Ghanem, J. Wouters, S. Aerts · 2019 · bioRxiv
Long-Read MDM4 Sequencing Reveals Aberrant Isoform Landscape in Metastatic Melanomas
Nehaal Patrick, Michael P. Markey · 2024 · International Journal of Molecular Sciences
The rise of new targets in melanoma
Xue Li Bai, Keith T. Flaherty · 2025 · British Journal of Dermatology
PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors
Margarida Espadinha, Stuart J. Conway, Maria M. M. Santos · 2020 · Elsevier eBooks
MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma
Jennifer Hüllein, Mikolaj Michal Slabicki, Maciej Rosołowski, Alexander Jethwa, Stefan Habringer, Katarzyna Tomska, Roma Kurilov, Junyan Lu, Sebastian Scheinost, Rabea Wagener et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Metastatic melanoma-A review of current and future perspective
Qurat‐ul‐Ain, Ismail, Muhammad · 2020 · arXiv (Cornell University)
Genomic alterations in hepatocellular carcinoma and their clinical application to genomic medicine
Taisuke Imamura, Yukiyasu Okamura · 2022 · HepatoBiliary Surgery and Nutrition
Ribosomal RNA transcription governs splicing through ribosomal protein RPL22
Wen-Jun Fan, Hester Liu, Gregory C. Stachelek, Asma Begum, Catherine E. Davis, Tony E Dorado, G. Ernst, William C. Reinhold, Busra Ozbek, Q. Zheng et al. · 2024 · bioRxiv
OGT Enhances Adriamycin Resistance of Breast Cancer by Promoting Glycolysis through MDM4 Upregulation in an O-GlcNAcylation-Dependent Manner.
Xiang Liu, Sihao Huang, Kuangye Zhu, Ludi Du · 2025 · Biochemical Genetics
A Small Molecule Compound, Berberine Reduces IgE but Not IgG Production via Promoting miRNA-34a-p53 Axis
Michelle A. Carnazza, Madison Spears, Raj Kumar Tiwari, Jan Geliebter, Nan Yang, Xiu-Min Li · 2025 · Cells
Preliminary Anti-Melanoma Activity of a Chlorogenic Acid-Based PROTAC Targeting MDM4, a Candidate Protein Identified by Proteomics
Zhiting Mei, Jiali Sun, Pengfei Zhao, Yiming Luo, Jine Niu, Danfei Huang · 2026 · Foods
Identification and characterization of BRAF⇔TP53 interactions in melanoma
Kayla T. O’Toole, Adamaris Martinez, Brandon Murphy, Gabriela Fort, Fatima Al-Sudani, Anastasia Prokofyeva, Sanjana Srinivas Boggaram, Eric A. Smith, Elliott L. Paine, Deevya Baral et al. · 2026 · Cell Reports
Animal Models of Melanoma
Zackie Aktary, Martin McMahon, Lionel Larue · 2019 · Springer eBooks
TFIIH kinase CDK7 antagonizes phenotype switching and emergence of drug tolerance in melanoma
Pietro Berico, Max Cigrang, Cathy Braun, Guillaume Davidson, Jérémy Sandoz, Stéphanie Le Gras, François Peyresaubes, Carlos Mario Genes Robles, Jean‐Marc Egly, Emmanuel Compe et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Transcriptome-Wide Association Study Reveals New Molecular Interactions Associated with Melanoma
Mohamed N. Saad, Mohamed Hamed · 2023 · Research Square
Molecular Diagnosis of Melanoma
Susana Ortiz‐Urda, Wilson Wai-Shing Ho, Albert Lee · 2024 · Springer eBooks
Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of cis -regulation
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Timothy Myers, Tongwu Zhang, Raj Chari, Erping Long, Thomas Rehling et al. · 2024 · medRxiv
Characterization of the BRAF interactome identifies BRAF V600E <=>TP53 interaction in melanoma
Kayla T. O’Toole, Adamaris Martinez, Brandon Murphy, Anastasia Proveyeka, Gabriela Fort, Fatima Al-Sudani, Sanjana Srinivas Boggaram, Elliott L. Paine, Deevya Baral, Joshua Lyon Andersen et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Targeting the Cell Cycle and p53 in Combination with BRAF-Directed Therapy
Dale Han, Keiran S.M. Smalley · 2014 · Cancer drug discovery and develogment/Cancer drug discovery and development
Expression levels of MDM2 and MDMX proteins and their associated effects on P53 in human liposarcomas
Nader Touqan · 2014 · UPT. Syiah Kuala University Library (Syiah Kuala University)
Quoi de neuf en cancérologie ?
Stéphane Dalle · 2012 · Annales de Dermatologie et de Vénéréologie
Reactivating p53 tumour suppressor function
Charlotte Harrison · 2012 · Nature Reviews Drug Discovery
Small molecules that affect the p53 pathway and their potential use in the treatment of cancer
Marijke C.C. Sachweh · 2014 · Figshare
Senescence Escape in Melanoma: Role of Spleen Tyrosine Kinase SYK
Marcel Deckert, Sophie Tartare‐Deckert · 2013 · Springer eBooks
Distinguishing Melanocytic Nevi from Melanoma by DNA Copy Number Changes: Array-Comparative Genomic Hybridization as a Research Tool
Ahmed Mahas · 2015 · CORE Scholar (Wright State University)
Inhibiting the Inhibitor: MDM4 as a Therapeutic Target in Cutaneous Melanoma
Kenneth Yee Tsai · 2012 · Journal watch
IN VIVO SIGNIFICANCE OF THE MDM4 AND P73 INTERACTION DURING DEVELOPMENT AND TUMORIGENESIS
Mehrnoosh Tashakori · 2015 · Digital Commons-TMC (Texas Medical Center)
Study of MicroRNA-34a mediated post transcriptional regulation of MDM4
Pooja Mandke · 2012 · CORE Scholar (Wright State University)
Exploring Chromatin-bound MDM2 Functions in Compromised Transcriptional Regulation of p53 Target Genes
Melissa Rosso · 2015 · CUNY Academic Works (City University of New York)
New Approaches to Signaling
R. Sullivan, K. Flaherty · 2017 · Springer eBooks
Avaliação dos mecanismos moleculares das vias de p53/ARF e IFNbeta envolvidos com a resposta de células de melanoma ao tratamento com os transgenes p19Arf e IFNbeta
Aline Hunger Ribeiro · 2016
Molecular Background of Cancer Recurrence
Ekaterina Kldiashvili, Lana Bokuchava · 2017 · Oncology & Cancer Case Reports
Key Aspects on Cancer Immunology
Ekaterina Kldiashvili · 2017 · Open Access Journal of Cancer & Oncology
Exploring nanobodies interrupting the interaction between p53 and MDM4
Sanem Sarıyar · 2019 · Sabanci University
Characterization of synthetic lethality between Mdm2 overexpression and genotoxic agents and identification of a novel function of the Mdmx oncogene in DNA repair
Alexia M. Carrillo · 2014
Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS -driven Melanomagenesis
Charles‐Antoine Assenmacher, Sara Francesca Santagostino, Mark A. Oyama, Jean‐Christophe Marine, Elise Bonvin, Enrico Radaelli · 2020 · Journal of Histochemistry & Cytochemistry
MDM4 (Murine Double Minute 4)
Annie Huang, Emily Yang, Manabu Kurokawa · 2016 · Springer eBooks
Faculty Opinions recommendation of Next-generation characterization of the Cancer Cell Line Encyclopedia.
Junjie Chen · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Ygal Haupt, Sue Haupt · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
MDM4 (Murine Double Minute 4)
Annie Huang, Emily Yang, Manabu Kurokawa · 2017 · Springer eBooks
Reativação da p53 Usando Pequenas Moléculas para Terapia Anticancerígena
Maria M. M. Santos, Ricardo Ferreira, Paulo Anastacio Furtado Pacheco · 2023 · Boletim da Sociedade Portuguesa de Química
Ezetimibe anticancer activity via the p53/Mdm2 pathway: Implications for RBBP6
Charmy Twala, Bonnie Russell, Sibusiso Tebogo Malindisa, Chamoné Munnik, Selisha Ann Sooklal, Monde McMillan Ntwasa · 2024 · Research Square
Das Onkoprotein Mdm4 und seine Wirkung auf die DNA-Replikation
Kai Wohlberedt · 2024
An Anti-Invasive Role for Mdmx through the RhoA GTPase under the Control of the NEDD8 Pathway
Lara J. Bou Malhab, Susanne Schmidt, Christine Fagotto‐Kaufmann, Emmanuelle Pion, Gilles Gadéa, Pierre Roux, François Fagotto, Anne Debant, Dimitris P. Xirodimas · 2024 · Cells
Tumor antigen PRAME promotes melanoma growth by inactivating p53 through the SIRT1-DBC1 axis
Yong-Kyu Lee, Hyeon Ho Heo, Ui‐Hyun Park, HyeSook Youn, Eun-Joo Kim, Soo‐Jong Um · 2025 · Oncogene