Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
Vanharanta, Sakari, Shu, Weiping, Brenet, Fabienne, Hakimi, A Ari, Heguy, Adriana, Viale, Agnes, Reuter, Victor E, Hsieh, James J-D +2 more·2013·Nature Medicine
DOI 10.1038/nm.3029
Cited by (216)
Items 101–200 of 216
- Inhibition of the Hypoxia-Inducible Factor 1α–Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart DiseasePeter Mirtschink, Corinne Bischof, Minh Duc Pham, Rahul Sharma, Sanjay P. Khadayate, Geetha Rossi, Niklaus Fankhauser, Shuyang Traub, Samuel Tobias Sossalla, Eman Hagag et al. · 2019 · Circulation
- Harnessing the genome for characterization of G‐protein coupled receptors in cancer pathogenesisMichael E. Feigin · 2013 · FEBS Journal
- Histone Deacetylase Inhibitors and Epigenetic Modifications as a Novel Strategy in Renal Cell CarcinomaSwathi Ramakrishnan, Роберто Пили · 2013 · The Cancer Journal
- Sunitinib activates Axl signaling in renal cell cancerJohannes Cornelis van der Mijn, Henk J. Broxterman, Jaco C. Knol, Sander R. Piersma, Richard R. de Haas, Henk Dekker, Thang V. Pham, Victor W. van Beusechem, Balázs Halmos, James Walter Mier et al. · 2016 · International Journal of Cancer
- Involvement of E3 Ligases and Deubiquitinases in the Control of HIF-α Subunit AbundanceKateryna I. Kubaichuk, Thomas Kietzmann · 2019 · Cells
- Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2α Inhibitor PT2385 In Vivo and In VitroCen Xie, Xiaoxia Gao, Dongxue Sun, You-Bo Zhang, Kristopher W. Krausz, Xuemei Qin, Frank J. Gonzalez · 2018 · Drug Metabolism and Disposition
- The up‐regulation of NDRG1 by HIF counteracts the cancer‐promoting effect of HIF in VHL‐deficient clear cell renal cell carcinomaZheng‐Yan Zhang, Shilong Zhang, Hui‐Ling Chen, Yuqin Mao, Zhan‐Ming Li, Chao‐Yue Kong, Bing Han, Jin Zhang, Yonghui Chen, Wei Xue et al. · 2020 · Cell Proliferation
- Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunitiesMinhong Shen, Yibin Kang · 2020 · Genes & Development
- ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancerKe Chen, Yu Gan, Kiranmai Gumireddy, Anping Li, Weimin Yao, Lu Gao, Shuliang Chen, Jun Hao, Ji Wang, Qihong Huang et al. · 2015 · Oncotarget
- Phenotypic plasticity and epithelial‐to‐mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinomaNavin Vig, Ian Campbell Mackenzie, Adrian Biddle · 2015 · Journal of Oral Pathology and Medicine
- Targeting Cancer Stem Cells: Therapeutic and diagnostic strategies by the virtue of nanoparticlesSamjhana Shrestha, Asmita Banstola, Jee‐Heon Jeong, Ji Hae Seo, Simmyung Yook · 2022 · Journal of Controlled Release
- Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomicsMaxime Janin, Verónica Dávalos, Manel Esteller · 2023 · Cancer and Metastasis Reviews
- Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathwayTing Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Li Xu · 2014 · International Journal of Molecular Medicine
- The circadian clock and the hypoxic response pathway in kidney cancerGianluigi Mazzoccoli, Angelo De Cata, Ada Piepoli, Manlio Vinciguerra · 2013 · Tumor Biology
- VPA inhibits renal cancer cell migration by targeting HDAC2 and down-regulating HIF-1αFeng‐Qiang Yang, Min Liu, Fengping Yang, Jian‐Ping Che, Wei Li, Wei Zhai, Guangchun Wang, Junhua Zheng, Xi Li · 2014 · Molecular Biology Reports
- Tumor Specific Epigenetic Silencing of Corticotropin Releasing Hormone -Binding Protein in Renal Cell Carcinoma: Association of Hypermethylation and MetastasisHossein Tezval, Natalia Dubrowinskaja, Inga Peters, Christel Reese, Katrin Serth, Faranaz Atschekzei, Jörg Hennenlotter, Arnulf Stenzl, Markus Antonius Kuczyk, Jürgen Serth · 2016 · PLoS ONE
- Mavorixafor, an Orally Bioavailable CXCR4 Antagonist, Increases Immune Cell Infiltration and Inflammatory Status of Tumor Microenvironment in Patients with MelanomaRobert H.I. Andtbacka, Yan Wang, Robert Hamilton Pierce, Jean S. Campbell, Melinda Lynne Yushak, Mohammed M. Milhem, Merrick Ross, Katie Niland, Robert D. Arbeit, Sudha Parasuraman et al. · 2022 · Cancer Research Communications
- The Role of Tumor Microenvironment in Regulating the Plasticity of Osteosarcoma CellsBoren Tian, Xiaoyun Du, Shiyu Zheng, Yan Zhang · 2022 · International Journal of Molecular Sciences
- High CXC chemokine receptor 4 expression is an adverse prognostic factor in patients with clear-cell renal cell carcinomaH An, Lei Xu, Yu Zhu, Tao� Lv, W. Liu, Y Liu, H Liu, L Chen, Jun Xu, Z Lin · 2014 · British Journal of Cancer
- The Physics of CancerCaterina A. M. La Porta, Stefano Zapperi · 2017 · Cambridge University Press eBooks
- Consequences of VHL Loss on Global DNA MethylomeRobinson, Claire M., Lefebvre, Francois, Poon, Betty P., Bousard, Aurelie, Fan, Xiaojun, Lathrop, Mark, Tost, Jorg, Kim, William Y., Riazalhosseini, Yasser, Ohh, Michael · 2018 · Scientific Reports
- Complex role of HIF in cancer: the known, the unknown, and the unexpectedEric L. Huang, Patricia D.B. Tiburcio, Hyunsung Choi · 2014 · Hypoxia
- Tyrosine-Kinase Inhibitors Therapies with Mainly Anti-Angiogenic Activity in Advanced Renal Cell Carcinoma: Value of PET/CT in Response EvaluationGirolamo Ranieri, Ilaria Marech, Artor Niccoli Asabella, Alessandra Di Palo, Mariangela Porcelli, Valentina Lavelli, Giuseppe Rubini, Cristina Ferrari, Cosmo Damiano Gadaleta · 2017 · International Journal of Molecular Sciences
- Tumor regression and potentiation of polymeric vascular disrupting therapy through reprogramming of a hypoxia microenvironment with temsirolimusHaiyang Yu, Na Shen, Yanli Bao, Li Chen, Zhaohui Tang · 2019 · Biomaterials Science
- TP53-Status-Dependent Oncogenic EZH2 Activity in Pancreatic CancerLennart Versemann, Shilpa Patil, Benjamin Steuber, Zhe Zhang, Waltraut Kopp, Hannah Elisa Krawczyk, Silke Kaulfuß, Bernd Wollnik, Philipp Ströbel, Albrecht Neeße et al. · 2022 · Cancers
- Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancerGrant Duncan Stewart, Thomas B. Powles, Christophe Van Neste, Alison M. Meynert, Fiach C. O’Mahony, Alexander Laird, Dieter L. D. Deforce, Filip Van Nieuwerburgh, Geert Trooskens, Wim Van Criekinge et al. · 2016 · Oncotarget
- Overexpression of BHLHE41, correlated with DNA hypomethylation in 3'UTR region, promotes the growth of human clear cell renal cell carcinomaZhouji Shen, Ling Zhu, Chao Zhang, Xiaobo Cui, Jun Lü · 2019 · Oncology Reports
- ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasisRuishan Wang, Akshita B. Bhatt, Benjamin A. Minden‐Birkenmaier, Olivia K. Travis, Srishti Tiwari, Hong Jia, Wojciech Rosikiewicz, Ophelie Martinot, Eleanor Childs, Robin Loesch et al. · 2023 · Science Advances
- Biomarker-informed care for patients with renal cell carcinomaM. Mckinnon, Brian I. Rini, Scott Mattox Haake · 2025 · Nature Cancer
- Reduced ING1 levels in breast cancer promotes metastasisSatbir Singh Thakur, Arvind K. Singla, Jie Chen, Uyen Tran, Yang Yang, Carolina Salazar, Anthony Martin Magliocco, Alexander C. Klimowicz, Frank Robert Jirik, Karl T. Riabowol · 2014 · Oncotarget
- The genetic script of metastasisGoodwin G. Jinesh, Andrew Scott Brohl · 2019 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
- Diverse Neoantigens and the Development of Cancer TherapiesRaghvendra Mohan Srivastava, Tanaya A. Purohit, Timothy An-thy Chan · 2020 · Seminars in Radiation Oncology
- Pharmacogenomics: New paradigms for targeted therapy based on individual response to drugsRam N Ganapathi, Mahrukh K. Ganapathi · 2013 · Urologic Oncology Seminars and Original Investigations
- Identification of PDE7B as a Potential Core Gene Involved in the Metastasis of Clear Cell Renal Cell CarcinomaYi Eve Sun, Junxia Zou, Wei Ouyang, Ke Chen · 2020 · Cancer Management and Research
- Combined Analyses of the VHL and Hypoxia Signaling Axes in an Isogenic Pairing of Renal Clear Cell Carcinoma CellsViktor Malec, Judy M. Coulson, Sylvie Urbé, Michael J. Clague · 2015 · Journal of Proteome Research
- New players in the landscape of renal cell carcinoma bone metastasis and therapeutic opportunitiesBeatrice Cesana, Claude Cochet, Odile Filhol · 2024 · International Journal of Cancer
- Research advances on epigenetics and cancer metabolismHengyi Han, Fan Feng, Haitao Li · 2021 · Journal of Zhejiang University (Medical Sciences)
- VHL Ser65 mutations enhance HIF2α signaling and promote epithelial-mesenchymal transition of renal cancer cellsXueyou Ma, Zenglai Tan, Qin Zhang, Kaifang Ma, Jun Xiao, Xiong Wang, Yanan Wang, Mengjie Zhong, Yu Wang, Jing Li et al. · 2022 · Cell & Bioscience
- A novel pVHL-independent but NEMO-driven pathway in renal cancer promotes HIF stabilizationA M Nowicka, Irina Häuselmann, Lubor Borsig, Sebastian Bolduan, Michael Schindler, Peter Schraml, Mathias F Heikenwälder, Holger Moch · 2015 · Oncogene
- Identification of DNA methylation signatures associated with poor outcome in lower-risk Stage, Size, Grade and Necrosis (SSIGN) score clear cell renal cell cancerLouis Y. El Khoury, Shuang Fu, Ryan A. Hlady, Ryan T. Wagner, Liguo Wang, Jeanette E. Eckel‐Passow, Erik P. Castle, Melissa Stanton, Robert Houston Thompson, Alexander Scott Parker et al. · 2021 · Clinical Epigenetics
- Multi-Omics Profiling to Assess Signaling Changes upon VHL Restoration and Identify Putative VHL Substrates in Clear Cell Renal Cell Carcinoma Cell LinesXuechun Wang, Jin Hu, Yihao Fang, Yanbin Fu, Bing Liu, Chao Zhang, Shan Feng, Xin Lü · 2022 · Cells
- Molecular Biology of Kidney CancerWilliam G. Kaelin · 2015 · Springer eBooks
- Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcomeLouis Y. El Khoury, Xiaoyu Pan, Ryan A. Hlady, Ryan T. Wagner, Shafiq Shaikh, Liguo Wang, Mitchell R. Humphreys, Erik P. Castle, Melissa Stanton, Thai H. Ho et al. · 2023 · Clinical Epigenetics
- Subtyping of renal cortical neoplasms in fine needle aspiration biopsies using a decision tree based on genomic alterations detected by fluorescence in situ hybridizationBanumathy Gowrishankar, Lynnette M. Cahill, Alexandra E. Arndt, Hikmat A Al‐Ahmadie, Oscar Lin, Kalyani Chadalavada, Seeta R. Chaganti, Gouri J. Nanjangud, Vundavalli V.V.S. Murty, Raju S. K. Chaganti et al. · 2014 · British Journal of Urology
- Metabolic reprogramming driven by EZH2 inhibition depends on cell–matrix interactionsTeresa W.‐M. Fan, Jahid M.M. Islam, Richard M. Higashi, Penghui Lin, Christine F. Brainson, Andrew N. Lane · 2023 · Journal of Biological Chemistry
- PHF13 epigenetically activates TGFβ driven epithelial to mesenchymal transitionYating Sun, Dan Li, Hongmei Liu, Yongye Huang, Fanyu Meng, Jiahao Tang, Zhanjun Li, Wanhua Xie · 2022 · Cell Death and Disease
- A new twist in neuroendocrine tumor research: Pacak-Zhuang syndrome, HIF-2α as the major player in its pathogenesis and future therapeutic optionsIvana Jochmanová, Ivica Lazúrová · 2014 · Biomedical Papers
- The genomic landscape of metastatic clear cell renal cell carcinoma after systemic therapyJohannes Cornelis van der Mijn, Kenneth Eng, Pooja Chandra, Evan M. Fernandez, Sinan Ramazanoglu, Alexandros Sigaras, Clara Oromendia, Lorraine J. Gudas, Scott T. Tagawa, David M. Nanus et al. · 2022 · Molecular Oncology
- Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal CarcinomaAsmaa Y. Abuhamad, Nurul Nadia Mohamad Zamberi, Sakari Vanharanta, Siti Nur Hasanah Mohd Yusuf, M. Aiman Mohtar, Saiful Effendi Syafruddin · 2023 · International Journal of Molecular Sciences
- The RNA demethylase FTO promotes glutamine metabolism in clear cell renal cell carcinoma through the regulation of SLC1A5Man Zhao, Dalin Zhang, Haowen Jiang, Nishanth Kuganesan, Suchitra Natarajan, Leighton Pu, Kaushik N. Thakkar, Hongjuan Zhao, Quynh‐Thu Le, Amato J. Giaccia et al. · 2025 · Science Advances
- Monitoring Chemokine Receptor Trafficking by Confocal Immunofluorescence MicroscopyAdriano Marchese · 2015 · Methods in enzymology on CD-ROM/Methods in enzymology
- Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugsEsther Arnaiz, Ana Miar, Esther Bridges, Naveen Prasad, Stephanie B. Hatch, Daniel V. Ebner, Charles Henderson Lawrie, Adrian Llewellyn Harris · 2021 · BMC Cancer
- Hypoxia Signaling—License to MetastasizeSakari Vanharanta, Joan Massagué · 2013 · Cancer Discovery
- The signaling pathway of hypoxia inducible factor and its role in renal diseasesSong Mao, Songming Huang · 2013 · Journal of Receptors and Signal Transduction
- PBX1, EMCN and ERG are associated with the sub-clusters and the prognosis of VHL mutant clear cell renal cell carcinomaHaiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang · 2022 · Scientific Reports
- Epigenetic markers and therapeutic targets for metastasisCarolyn J. Kravitz, Qin Yan, Don X. Nguyen · 2023 · Cancer and Metastasis Reviews
- Personalized Medicine for Nervous System Manifestations of von Hippel–Lindau DiseaseVictoria A. Schunemann, Kristin Michelle Huntoon, Russell R. Lonser · 2016 · Frontiers in Surgery
- Characterization of RNA editome in primary and metastatic lung adenocarcinomasLihua Peng, Leo J. Lee, Heng Xiong, Hong Lin Su, Jun-Hua Rao, Dakai Xiao, Jianxing He, Kui Wu, Dongbing Liu · 2016 · Oncotarget
- Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cellsGuang Chen, Jinye Xu, Jie Chen, Jian-Xin Zhang, Jun Zhou, Yong Liang, Xiaofei Ding · 2016 · Oncotarget
- Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in Natural Killer cellsNicholas Tompkins, Brian R. MacKenzie, Collin Ward, David Salgado, Andrew M. Leidal, Craig McCormick, Bill Pohajdak · 2014 · Biochemical and Biophysical Research Communications
- The SWI/SNF complex member SMARCB1 supports lineage fidelity in kidney cancerLudovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Yvonne Warren, Paulo Rodrigues, Giovanni Ciriello et al. · 2023 · iScience
- Bevacizumab as First-Line Therapy for Patients With Brain Metastases From Renal Carcinoma: A Case SeriesFable Zustovich, Alessandra Ferro, Patrizia Farina · 2014 · Clinical Genitourinary Cancer
- Microarray Profiling of Human Renal Cell Carcinoma: Identification for Potential Biomarkers and Critical PathwaysWei Li, Wei Zhu, Jian‐Ping Che, Wei Sun, Min Liu, Bo Peng, Junhua Zheng · 2013 · Kidney & Blood Pressure Research
- The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programsTreg M. Grubb, Pooneh Koochaki, Sayed Matar, Fatme Ghandour, Marc Machaalani, Eddy Saad, Cerise Tang, Ed Reznik, Jesminara Khatun, Carleigh Salem et al. · 2025 · Nature Communications
- Low EGR1 expression predicts poor prognosis in clear cell renal cell carcinomaZhengyan Zhang, Shilong Zhang, Huiling Chen, Yuqin Mao, Chao‐Yue Kong, Zhanming Li, Li‐Shun Wang, Ming Ma, Bing Han · 2021 · Pathology - Research and Practice
- von Hippel-Lindau Exonic Methylation Analysis Using MALDI-TOF Mass SpectrometryFei Lian, Shilpa Sreedharan, Rebecca S. Arnold, Viraj A. Master, Kenneth Ogan, John G. Pattaras, David L. Roberts, John A. Petros · 2014 · The Journal of Urology
- Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progressionMarco Sciacovelli, Aurélien J. F. Dugourd, Lorea Valcárcel-Jiménez, Ming Hui Yang, Efterpi Nikitopoulou, Ana S.H. Costa, Laura Tronci, Veronica Caraffini, Paulo Rodrigues, Christina Schmidt et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- S‐(4‐Methoxyphenyl)‐4‐methoxybenzenesulfonothioate as a Promising Lead Compound for the Development of a Renal Carcinoma AgentCamilla I. Nantes, Ingrid D. Pereira, Ruoli Bai, Ernest Hamel, James C. Burnett, Rodrigo Juliano Oliveira, Maria de Fátima Cepa Matos, Adilson Beatriz, Murilo K. A. Yonekawa, Renata Trentin Perdomo et al. · 2019 · ChemMedChem
- Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilitiesJianfeng Ge, Shoko Hirosue, Leticia Castillon, Saroor A. Patel, Ludovic Wesolowski, Anna Dyas, Cissy Yong, Sanne de Haan, Jarno Drost, Grant Duncan Stewart et al. · 2025 · EMBO Molecular Medicine
- Construction and validation of a chromatin regulator-related gene signature for prognostic and therapeutic significance of clear cell renal cell carcinomaChangzheng Zhang, Jiayi Zeng, Chujin Ye, Kaiwen Tian, Zhiyong Xian · 2024 · Translational Cancer Research
- Molecular Biology of Kidney CancerWilliam G. Kaelin · 2011 · Springer eBooks
- Molecular Genetics of Renal Cell CarcinomaTomoya Fukawa, Nicholas Brian Shannon, Dachuan Huang, Jing Ying Tan, Xiaosai Yao, Steve Rozen, Patrick Tan, Bin Tean Teh · 2017 · Springer eBooks
- Endogenous HIF2A reporter systems for high-throughput functional screeningM. Nazhif Zaini, Saroor A. Patel, Saiful Effendi Syafruddin, Paulo Rodrigues, Sakari Vanharanta · 2018 · Scientific Reports
- Lineage-Specific Transcription Factors in CarcinogenesisCharles J. David, Sakari Vanharanta · 2024 · Annual Review of Cancer Biology
- Activation of RHO-GTPase gene pattern correlates with adverse clinical outcome and immune microenvironment in clear cell renal cell carcinomaKehang Guo, Pengyue Ma, Qi Yang, Lingli Xu, Biixiong Zhang, Hong Zhang, Zhongwen Zheng, Zewei Zhuo · 2025 · Clinical and Experimental Medicine
- Targeting GABARAPL1/HIF-2a axis to induce tumor cell apoptosis in nasopharyngeal carcinoma.Xiaopeng Huang, Liya Zhou, Jiawei Chen, Shuai Zhang · 2024 · PubMed Central
- Inhalational Anesthetic Agents and Their Effects on Cancer Cell BiologyNicholas J. S. Perry, Daqing Ma · 2015 · Current anesthesiology reports
- Characterization of Clear Cell Renal Cell Carcinoma with a Wild-type von Hippel-Lindau Tumor Suppressor Gene: Limitation of Survival Expectations Using Single-gene AlterationKeiichi Kondo, Masahiro Yao · 2015 · European Urology Focus
- SWI/SNF ATPase silenced HLF potentiates lung metastasis in solid cancersJin Zhou, Austin J. Hepperla, Jeremy M. Simon, Kangsan Kim, Qing Hu, Chuanhai Zhang, Lei Dong, Lianxin Hu, Cheng Zhang, Chengheng Liao et al. · 2025 · Nature Communications
- Tumour sampling conditions perturb the metabolic landscape of clear cell renal cell carcinomaCissy Yong, Christina Schmidt, Ming Hui Yang, Alex von Kriegsheim, Anne Yvonne Warren, Shubha Anand, James N. Armitage, Antony C. P. Riddick, Thomas J. Mitchell, Vishal Patil et al. · 2025 · Nature Communications
- BCL-XL dependence is a subtype agnostic actionable feature of difficult-to-treat kidney cancersTupa Basuroy, Treg M. Grubb, Ananthan Sadagopan, Xingping Qin, Kylee Madison, Autumn Hall, Belinda B. Willard, Sakari Vanharanta, Kristopher A. Sarosiek, Srinivas R. Viswanathan et al. · 2026 · Cell Death and Disease
- Investigation of the Role of microRNA Associated with the VHL-HIFα-Dependent Pathway in Patients with Clear Cell Renal Cell CarcinomaElizaveta A. Klimentova, I. R. Gilyazova, Marina Bermisheva, А. М. Блинникова, Ruslan I. Safiullin, Адель Альбертович Измайлов, Baofeng Yang, В. Н. Павлов, Э. К. Хуснутдинова · 2020 · Russian Journal of Genetics
- CancerHarold I. Zeliger · 2022 · Elsevier eBooks
- Preclinical Models of Brain MetastasisLucía Zhu, Manuel Valiente · 2020 · Springer eBooks
- Molecular Determinants of Metastasis in Renal Cell Cancer: Tracking Down the Real KillerRichard J. Lee · 2015 · The Journal of Urology
- RNA-sequencing analysis in B-cell acute lymphoblastic leukemia reveals aberrant gene expression and splicing alterationsOlha Kholod · 2017
- Developmental reversion underlies resistance to immune checkpoint blockade in kidney cancerDig Vijay Kumar Yarlagadda, Zhenghan Wang, Hui Jiang, Lynda H. Vuong, Andrea López Sanmiguel, Ching-Yeuh Yang, Ritesh R. Kotecha, Ying‐Bei Chen, A. Ari Hakimi, Christina S. Leslie et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Going places with VHLNicola Jane McCarthy · 2012 · Nature reviews. Cancer
- From molecular understanding to clinical advancesChung‐Han Lee, Robert John Motzer · 2013 · Nature Reviews Urology
- A regulatory network of Mdm2 and members of the Polycomb Group (PcG) familyMaria Magdalena Wienken · 2016
- A possible IDO1- TSP1 role in breast cancer dormancyBruno Lopes-Bastos · 2017 · ORCA Online Research @Cardiff (Cardiff University)
- Endogenous Reporter Systems for High-Throughput Functional Screening in Clear Cell Renal Cell CarcinomaM. Nazhif Zaini · 2019 · Apollo (University of Cambridge)
- Faculty Opinions recommendation of Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.Andrew C. Dudley · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- EZH2-GATA6 axis in Pancreatic ductal adenocarcinomaShilpa Patil · 2020
- TP53-status dependent oncogenic EZH2 Activity in Pancreatic CancerLennart Versemann · 2022
- Targeting GABARAPL1/HIF-2a in nasopharyngeal carcinomaXiaopeng Huang, Liya Zhou, Jiawei Chen, Shuai Zhang · 2023 · Research Square
- Additional file 7 of VHL Ser65 mutations enhance HIF2α signaling and promote epithelial-mesenchymal transition of renal cancer cellsXueyou Ma, Zenglai Tan, Qin Zhang, Kaifang Ma, Jun Xiao, Xiong Wang, Yanan Wang, Mengjie Zhong, Yu Wang, Li, Jing et al. · 2022 · Figshare
- Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancerRichard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh · 2025 · FEBS Open Bio
- Genotype-phenotype correlation in Iranian retinal hemangioblastoma patients and genetic diagnosis algorithm for Von Hippel-Lindau diseaseFatemeh Azimi, Masood Naseripour, Golnaz Khakpoor · 2025 · Ophthalmic Genetics
- Reactive oxygen species (ROS) and late-stage cancer (Cancer metastasis)Milena Krajnović, Snežana Jovanović-Ćupić, Bojana Kožik, Ana Božović · 2025 · Elsevier eBooks