Broadly neutralizing hemagglutinin stalk–specific antibodies require FcγR interactions for protection against influenza virus in vivo

DiLillo, David J, Tan, Gene S, Palese, Peter, Ravetch, Jeffrey V·2014·Nature Medicine

DOI 10.1038/nm.3443

Cited by (763)

Items 201–300 of 763

A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody
Aitor Nogales, Michael S. Piepenbrink, Jiong Wang, Sandra Ortega, Madhubanti Basu, Christopher Fucile, John Jay Treanor, Alexander F. Rosenberg, Martin Stuart Zand, Michael C. Keefer et al. · 2018 · Scientific Reports
A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains
Felix Broecker, Sean T. H. Liu, Nungruthai Suntronwong, Weina Sun, Mark J. Bailey, Raffael Nachbagauer, Florian Krammer, Peter Palese · 2019 · npj Vaccines
Antibody Effector Functions Mediated by Fcγ-Receptors Are Compromised during Persistent Viral Infection
Andreas Wieland, Rangaiah Shashidharamurthy, Alice Oliffson Kamphorst, Jin‐Hwan Han, Rachael D. Aubert, Biswa Choudhury, Sean R. Stowell, Junghwa Lee, George A. Punkosdy, Mark Jay Shlomchik et al. · 2015 · Immunity
High Antibody-Dependent Cellular Cytotoxicity Antibody Titers to H5N1 and H7N9 Avian Influenza A Viruses in Healthy US Adults and Older Children
Masanori Terajima, Mary Dawn T. Co, John Cruz, Francis A. Ennis · 2015 · The Journal of Infectious Diseases
Polyclonal epitope mapping reveals temporal dynamics and diversity of human antibody responses to H5N1 vaccination
Julianna Han, Aaron J. Schmitz, Sara T. Richey, Ya-Nan Dai, Hannah L. Turner, Bassem M. Mohammed, Daved H. Fremont, Ali H. Ellebedy, Andrew B. Ward · 2021 · Cell Reports
Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses
Syed Mohammad Moin, Jeffrey C. Boyington, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Gabriele Cerutti, Crystal Sao‐Fong Cheung, Alberto Cagigi, John R. Gallagher, Joshua Brand, Madhu S. Prabhakaran et al. · 2022 · Immunity
An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A viruses
Feifei Xiong, Chi Zhang, Baoyuan Shang, Mei Zheng, Qi Wang, Yahong Ding, Jian Luo, Xiuling Li · 2023 · Emerging Microbes & Infections
Protective Immunity Based on the Conserved Hemagglutinin Stalk Domain and Its Prospects for Universal Influenza Vaccine Development
Madhu Khanna, Sachin Sharma, Binod Kumar, Roopali Rajput · 2014 · BioMed Research International
Pulmonary immunity to viruses
S. Rameeza Allie, Troy D. Randall · 2017 · Clinical Science
A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin
Fei Yu, Song He, Yanling Wu, So Young Chang, Lili Wang, Wei Li, Binbin Hong, Shuai Xia, Chunyu Wang, Surender Khurana et al. · 2017 · Cell Host & Microbe
Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies
Goran Bajic, Cees E. van der Poel, Masayuki Kuraoka, Aaron G. Schmidt, Michael C. Carroll, Garnett H. Kelsoe, Stephen C. Harrison · 2019 · Scientific Reports
Broadly Protective Strategies Against Influenza Viruses: Universal Vaccines and Therapeutics
Olivia A. Vogel, Balaji Manicassamy · 2020 · Frontiers in Microbiology
A Sample-Sparing Multiplexed ADCP Assay
Audrey L. Butler, Jonathan K. Fallon, Galit Alter · 2019 · Frontiers in Immunology
The protective potential of Fc‐mediated antibody functions against influenza virus and other viral pathogens
Hillary A. Vanderven, Stephen John Kent · 2020 · Immunology and Cell Biology
Is It Possible to Develop a “Universal” Influenza Virus Vaccine?
Davide Angeletti, Jonathan Wilson Yewdell · 2017 · Cold Spring Harbor Perspectives in Biology
A Broadly Reactive Human Anti-hemagglutinin Stem Monoclonal Antibody That Inhibits Influenza A Virus Particle Release
Seiya Yamayoshi, Ryuta Uraki, Mutsumi Ito, Maki Kiso, Sumiho Nakatsu, Atsuhiro Yasuhara, Kohei Oishi, Tadahiro Sasaki, Kazuyoshi Ikuta, Yoshihiro Kawaoka · 2017 · EBioMedicine
Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses
Peter Halfmann, Steven J. Frey, Kathryn Loeffler, Makoto Kuroda, Tadashi Maemura, Tammy Armbrust, Jie E Yang, Yixuan Jacob Hou, Ralph Steven Baric, Elizabeth Wright et al. · 2022 · EBioMedicine
Human seasonal influenza A viruses induce H7N9-cross-reactive antibody-dependent cellular cytotoxicity (ADCC) antibodies that are directed towards the nucleoprotein
Sinthujan Jegaskanda, Mary Dawn T. Co, John Cruz, Kanta Subbarao, Francis A. Ennis, Masanori Terajima · 2016 · The Journal of Infectious Diseases
Universal immunity to influenza must outwit immune evasion
Sergio M. Quiñones‐Parra, Liyen Loh, Lorena E. Brown, Katherine Kedzierska, Sophie A. Valkenburg · 2014 · Frontiers in Microbiology
HA Antibody-Mediated FcγRIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids
Freek Cox, Ted Kwaks, Boerries Brandenburg, Martin H. Koldijk, Vincent Klaren, Bastiaan Smal, Hans J. W. M. Korse, Eric Geelen, Lisanne Tettero, David Zuijdgeest et al. · 2016 · Frontiers in Immunology
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
Gunnveig Grødeland, Even Fossum, Bjarne Bogen · 2015 · Frontiers in Immunology
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein
Bert Schepens, Koen Sedeyn, Liesbeth Vande Ginste, Sarah De Baets, Michael Schotsaert, Kenny Roose, Lieselot Houspie, Marc A. Van Ranst, Brian E. Gilbert, Nico van Rooijen et al. · 2014 · EMBO Molecular Medicine
Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines
Troy C. Sutton, Saborni Chakraborty, Vamsee V. A. Mallajosyula, Elaine W. Lamirande, Ketaki Ganti, Kevin W. Bock, Ian N. Moore, Raghavan Varadarajan, Kanta Subbarao · 2017 · npj Vaccines
A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection
Cody S. Nelson, Betsy C. Herold, Sallie R. Permar · 2018 · npj Vaccines
Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model
Wen‐Chun Liu, Raffael Nachbagauer, Daniel Stadlbauer, Alicia Solórzano, Francesco Berlanda Scorza, Adolfo García‐Sastre, Peter Palese, Florian Krammer, Randy A. Albrecht · 2019 · Frontiers in Immunology
Targeting Hemagglutinin: Approaches for Broad Protection against the Influenza A Virus
Yun Zhang, Cong Xu, Hao Zhang, George Dacai Liu, Chunyi Xue, Yongchang Cao · 2019 · Viruses
A Human Anti-M2 Antibody Mediates Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Cytokine Secretion by Resting and Cytokine-Preactivated Natural Killer (NK) Cells
Venkateswara Rao Simhadri, Milena Dimitrova, John L. Mariano, Olatz Zenarruzabeitia, Weimin Zhong, Tatsuhiko Ozawa, Atsushi Muraguchi, Hiroyuki Kishi, Maryna C. Eichelberger, Francisco Borrego · 2015 · PLoS ONE
Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies
Michael Schotsaert, Tine Ysenbaert, Anouk Smet, Bert Schepens, Dieter Vanderschaeghe, Svetlana S. Stegalkina, Thorsten U. Vogel, Nico Callewaert, Walter C. Fiers, Xavier Saelens · 2016 · Scientific Reports
Immunological aspects of rabies: a literature review
Iana Suly Santos Katz, Fernanda Guedes, Elaine Raniero Fernandes, Sandriana dos Ramos Silva · 2017 · Archives of Virology
Neuraminidase expressing virus-like particle vaccine provides effective cross protection against influenza virus
Ki‐Hye Kim, Young‐Tae Lee, Soojin Park, Yu‐Jin Jung, Youri Lee, Eun‐Ju Ko, Yu-Jin Kim, Xuguang Li, Sang‐Moo Kang · 2019 · Virology
Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo
Lena Hansen, Meagan McMahon, Hannah L. Turner, Xueyong Zhu, Jackson S. Turner, Gabriel Ozorowski, Daniel Stadlbauer, Juha Vahokoski, Aaron J. Schmitz, Amena A. Rizk et al. · 2023 · Immunity
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response
Merika Treants Koday, Jorgen Nelson, Aaron A. Chevalier, Michael Koday, Hannah Maryam Kalinoski, Lance J. Stewart, Lauren P. Carter, Travis Nieusma, Peter S. Lee, Andrew B. Ward et al. · 2016 · PLoS Pathogens
Antibody Responses with Fc-Mediated Functions after Vaccination of HIV-Infected Subjects with Trivalent Influenza Vaccine
Anne B. Kristensen, William N. Lay, Fernanda Ana‐Sosa‐Batiz, Hillary A. Vanderven, Vijaya Madhavi, Karen Laurie, Louise A. Carolan, Bruce D. Wines, Philip Mark Hogarth, Adam K. Wheatley et al. · 2016 · Journal of Virology
Pharmacokinetic and Pharmacodynamic Considerations in the Design of Therapeutic Antibodies
Douglas D. Leipold, Saileta Prabhu · 2018 · Clinical and Translational Science
Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection
Matthew Sidney Parsons, Sarah B. Lloyd, Wen Shi Lee, Anne B. Kristensen, Thakshila H. Amarasena, Brandon F. Keele, Jeffrey D. Lifson, Celia C. LaBranche, David C. Montefiori, Bruce D. Wines et al. · 2017 · Science Translational Medicine
Neutrophils and Influenza: A Thin Line between Helpful and Harmful
Sneha T. George, Jonathan Lai, Julia Ma, Hannah D. Stacey, Matthew S. Miller, Caitlin E. Mullarkey · 2021 · Vaccines
Next Generation of Computationally Optimized Broadly Reactive HA Vaccines Elicited Cross-Reactive Immune Responses and Provided Protection against H1N1 Virus Infection
Ying Huang, Monique França, James D. Allen, Hua Shi, Ted M. Ross · 2021 · Vaccines
Heterologous Prime-Boost Vaccination with MF59-Adjuvanted H5 Vaccines Promotes Antibody Affinity Maturation towards the Hemagglutinin HA1 Domain and Broad H5N1 Cross-Clade Neutralization
Surender Khurana, Elizabeth M. Coyle, Milena Dimitrova, Flora Castellino, Karl G. Nicholson, Giuseppe Del Giudice, Hana Golding · 2014 · PLoS ONE
An H7N1 Influenza Virus Vaccine Induces Broadly Reactive Antibody Responses against H7N9 in Humans
Florian Krammer, Åsne Jul‐Larsen, Irina Margine, Ariana Hirsh, Haakon Sjursen, Maria Cristina Fleischmann Alves Zambon, Rebecca Jane Cox · 2014 · Clinical and Vaccine Immunology
Evaluation of the Safety and Immunogenicity of a Candidate Pandemic Live Attenuated Influenza Vaccine (pLAIV) Against Influenza A(H7N9)
Mohammad Mahdee Sobhanie, Yumiko Matsuoka, Sinthujan Jegaskanda, Theresa F. Fitzgerald, Raburn M. Mallory, Yuyan Chen, Catherine J. Luke, John Jay Treanor, Kanta Subbarao · 2015 · The Journal of Infectious Diseases
How Immunoglobulin G Antibodies Kill Target Cells
Markus Biburger, Anja Lux, Falk Nimmerjahn · 2014 · Advances in immunology
Fc functional antibodies in humans with severe H7N9 and seasonal influenza
Hillary A. Vanderven, Lu Liu, Fernanda Ana‐Sosa‐Batiz, Thi H. O. Nguyen, Yanmin Wan, Bruce D. Wines, Philip Mark Hogarth, Danielle Tilmanis, Arnold Reynaldi, Matthew Sidney Parsons et al. · 2017 · JCI Insight
Increasing the breadth and potency of response to the seasonal influenza virus vaccine by immune complex immunization
Jad Maamary, Taia T. Wang, Gene S. Tan, Peter Palese, Jeffrey V. Ravetch · 2017 · Proceedings of the National Academy of Sciences
On the road to ending the COVID-19 pandemic: Are we there yet?
J. Case, Emma S. Winkler, J. Errico, Michael S. Diamond · 2021 · Virology
In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice
Troy C. Sutton, Elaine W. Lamirande, Kevin W. Bock, Ian N. Moore, Wouter Koudstaal, Muniza Rehman, Gerrit Jan Weverling, Jaap Goudsmit, Kanta Subbarao · 2017 · Journal of Virology
Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice
Carly M. Bliss, Andrea Jean Parsons, Raffael Nachbagauer, Jennifer R. Hamilton, Federica Cappuccini, Marta Ulaszewska, Jason Paul Webber, Aled Clayton, Adrian V. S. Hill, Lynda Coughlan · 2019 · Molecular Therapy — Methods & Clinical Development
Influenza A Virus Antibodies with Antibody-Dependent Cellular Cytotoxicity Function
Rongyuan Gao, Zizhang Sheng, Chithra C. Sreenivasan, Dan Wang, Feng Li · 2020 · Viruses
Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity
Kathryn A. Bowman, Daniel Stein, Sally A. Shin, Kathie G. Ferbas, Nicole H. Tobin, Colin J. Mann, Stephanie Fischinger, Erica Ollmann Saphire, Douglas A. Lauffenburger, Anne W. Rimoin et al. · 2022 · mBio
The road to a more effective influenza vaccine: Up to date studies and future prospects
Kaori Sano, Akira Ainai, Tadaki Suzuki, Hideki Hasegawa · 2017 · Vaccine
Influenza Virus Infection Enhances Antibody-Mediated NK Cell Functions via Type I Interferon-Dependent Pathways
Sinthujan Jegaskanda, Hillary A. Vanderven, Hyon‐Xhi Tan, Sheilajen Alcântara, Kathleen M. Wragg, Matthew Sidney Parsons, Amy W. Chung, Jennifer A. Juno, Stephen John Kent · 2018 · Journal of Virology
Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design
Sinthujan Jegaskanda, Hillary A. Vanderven, Adam K. Wheatley, Stephen John Kent · 2017 · Human Vaccines & Immunotherapeutics
Avian Influenza A Virus Pandemic Preparedness and Vaccine Development
Rory D. de Vries, Sander Herfst, Mathilde Richard · 2018 · Vaccines
Effector mechanisms of influenza-specific antibodies: neutralization and beyond
Federica Sicca, Sam Neppelenbroek, Anke L. W. Huckriede · 2018 · Expert Review of Vaccines
Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine
Christopher E. Lopez, Kevin L. Legge · 2020 · Vaccines
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
Ruipeng Lei, Wooseob Kim, Huibin Lv, Zongjun Mou, Michael J. Scherm, Aaron J. Schmitz, Jackson S. Turner, Timothy J.C. Tan, Yiquan Wang, Wenhao O. Ouyang et al. · 2023 · Immunity
Relationship of Preexisting Influenza Hemagglutination Inhibition, Complement-Dependent Lytic, and Antibody-Dependent Cellular Cytotoxicity Antibodies to the Development of Clinical Illness in a Prospective Study of A(H1N1)pdm09 Influenza in Children
Mary Dawn T. Co, Masanori Terajima, Stephen James Thomas, Richard G. Jarman, Kamonthip Rungrojcharoenkit, Stefan Fernandez, In‐Kyu Yoon, Darunee Buddhari, John Cruz, Francis A. Ennis · 2014 · Viral Immunology
Implications of broadly neutralizing antibodies in the development of a universal influenza vaccine
Alice Cho, Jens Wrammert · 2016 · Current Opinion in Virology
Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses
Austin W. Boesch, Nana Yaw Osei‐Owusu, Andrew R. Crowley, Thach H. Chu, Ying N. Chan, Joshua A. Weiner, Pranay Bharadwaj, Rufus Hards, Mark E. Adamo, Scott A. Gerber et al. · 2016 · Frontiers in Immunology
Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections
Yung-Chieh Tseng, Chia-Yu Wu, Mingliang Liu, Ting-Hua Chen, Wan-Ling Chiang, Yueh‐Hsiang Yu, Jia‐Tsrong Jan, Kuo‐I Lin, Chi‐Huey Wong, Che Ma · 2019 · Proceedings of the National Academy of Sciences
Differential requirements for FcγR engagement by protective antibodies against Ebola virus
Stylianos Bournazos, David J. DiLillo, Arthur J. Goff, Pamela J. Glass, Jeffrey V. Ravetch · 2019 · Proceedings of the National Academy of Sciences
Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response
Jonathan D. Herman, Chuangqi Wang, Carolin Loos, Hyunah Yoon, Johanna Rivera, M. Eugenia Dieterle, Denise Haslwanter, Rohit K. Jangra, Robert H. Bortz, Katharine J. Bar et al. · 2021 · Nature Communications
Options and Obstacles for Designing a Universal Influenza Vaccine
Yo Han Jang, Baik Lin Seong · 2014 · Viruses
Modified Vaccinia Virus Ankara Encoding Influenza Virus Hemagglutinin Induces Heterosubtypic Immunity in Macaques
Kelsey R. Florek, Jason T. Weinfurter, Sinthujan Jegaskanda, Joseph N. Brewoo, Tim D. Powell, Ginger R. Young, Subash C. Das, Masato Hatta, Karl W. Broman, Olav Hungnes et al. · 2014 · Journal of Virology
Sequential Infection in Ferrets with Antigenically Distinct Seasonal H1N1 Influenza Viruses Boosts Hemagglutinin Stalk-Specific Antibodies
Greg A. Kirchenbaum, Donald M. Carter, Ted M. Ross · 2015 · Journal of Virology
A virus-like particle vaccine candidate for influenza A virus based on multiple conserved antigens presented on hepatitis B tandem core particles
Alejandro Ramirez, Stephen Morris, Sophie Maucourant, Isabella D'Ascanio, Vincenzo Crescente, I‐Na Lu, Sophie Farinelle, Claude P. Muller, Michael Whelan, William M. Rosenberg · 2018 · Vaccine
Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
Shannon R. Christensen, Sushila A. Toulmin, Trevor Griesman, Lois E. Lamerato, Joshua G. Petrie, Emily Toth Martin, Arnold S. Monto, Scott E. Hensley · 2019 · Journal of Virology
Role of Fc–FcγR interactions in the antitumor activity of therapeutic antibodies
Bryan C. Barnhart, Michael M. Quigley · 2016 · Immunology and Cell Biology
IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo
Vinayak Brahmakshatriya, Yi Kuang, Priyadharshini Devarajan, Jingya Xia, Wenliang Zhang, Allen M. Vong, Susan L. Swain · 2017 · The Journal of Immunology
Prospects of HA-Based Universal Influenza Vaccine
Anwar M. Hashem · 2015 · BioMed Research International
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Demo Yemane Tesfaye, Arnar Gudjonsson, Bjarne Bogen, Even Fossum · 2019 · Frontiers in Immunology
Non-neutralizing Antibodies Directed at Conservative Influenza Antigens
Elena S. Sedova, Д. Н. Щербинин, Andrei A. Lysenko, S. V. Alekseeva, E. A. Artemova, М. М. Шмаров · 2019 · Acta Naturae
Influenza Hemagglutinin Nanoparticle Vaccine Elicits Broadly Neutralizing Antibodies against Structurally Distinct Domains of H3N2 HA
Alyse D. Portnoff, Nita Patel, Michael J. Massare, Haixia Zhou, Jing-Hui Tian, Bin Zhou, Vivek Shinde, Gregory M. Glenn, Gale Smith · 2020 · Vaccines
A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface
Kevin R. McCarthy, Jiwon Lee, Akiko Watanabe, Masayuki Kuraoka, Lindsey R. Robinson‐McCarthy, George Georgiou, Garnett H. Kelsoe, Stephen C. Harrison · 2021 · mBio
Unmasking Stem-Specific Neutralizing Epitopes by Abolishing N-Linked Glycosylation Sites of Influenza Virus Hemagglutinin Proteins for Vaccine Design
Wen‐Chun Liu, Jia‐Tsrong Jan, Yun‐Ju Huang, Ting‐Hsuan Chen, Suh‐Chin Wu · 2016 · Journal of Virology
Strategies to induce broadly protective antibody responses to viral glycoproteins
Florian Krammer · 2017 · Expert Review of Vaccines
Beyond Viral Neutralization
George K. Lewis, Marzena Pazgier, David T. Evans, Guido Ferrari, Stylianos Bournazos, Matthew Sidney Parsons, Nicole Flore Bernard, Andrés Finzi · 2017 · AIDS Research and Human Retroviruses
Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans
Daniel Stadlbauer, Arvind Rajabhathor, Fatima Amanat, Daniel Kaplan, Abusaleh Masud, John Jay Treanor, Ruvim Izikson, Manon M. J. Cox, Raffael Nachbagauer, Florian Krammer · 2017 · mSphere
Carbohydrate–protein interactions and multivalency: implications for the inhibition of influenza A virus infections
Wenjing Lu, Roland J. Pieters · 2019 · Expert Opinion on Drug Discovery
Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies
Yu Adachi, Keisuke Tonouchi, Arnone Nithichanon, Masayuki Kuraoka, Akiko Watanabe, Ryo Shinnakasu, Hideki Asanuma, Akira Ainai, Yusuke Ohmi, Takuya Yamamoto et al. · 2019 · Nature Communications
The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD
Fatima Amanat, Mahima Thapa, Tinting Lei, Shaza M. Sayed Ahmed, Daniel C. Adelsberg, Juan Manuel Carreño, Shirin Strohmeier, Aaron J. Schmitz, Sarah Zafar, Julian Q. Zhou et al. · 2021 · medRxiv
Selective transfer of maternal antibodies in preterm and fullterm children
Sepideh Dolatshahi, Audrey L. Butler, Christian Pou, Ewa Henckel, Anna Karin Bernhardsson, Anna Gustafsson, Kajsa Bohlin, Sally A. Shin, Douglas A. Lauffenburger, Petter Brodin et al. · 2022 · Scientific Reports
Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge
Ching‐Lin Hsieh, Sarah R. Leist, Emily Happy Miller, Ling Zhou, John M. Powers, Alexandra L. Tse, Albert Wang, Ande West, Mark R. Zweigart, Jonathan Cummings Schisler et al. · 2024 · Nature Communications
Antibody-Based Strategies to Prevent and Treat Influenza
Zachary H. Shriver, José Trevejo, Ram Sasisekharan · 2015 · Frontiers in Immunology
Antibody-Dependent Cellular Cytotoxicity Responses to Seasonal Influenza Vaccination in Older Adults
Hillary A. Vanderven, Sinthujan Jegaskanda, Bruce D. Wines, Philip Mark Hogarth, Sarina Carmuglia, Steven P. Rockman, Amy W. Chung, Stephen John Kent · 2017 · The Journal of Infectious Diseases
Vaccinating for natural killer cell effector functions
Helen R. Wagstaffe, Jason P. Mooney, Eleanor M. Riley, Martin Rhys Goodier · 2018 · Clinical & Translational Immunology
Elicitation of Broadly Protective Antibodies following Infection with Influenza Viruses Expressing H1N1 Computationally Optimized Broadly Reactive Hemagglutinin Antigens
Giuseppe Andrea Sautto, Greg A. Kirchenbaum, Jeffrey W. Ecker, Anne-Gaelle Bebin-Blackwell, Spencer R. Pierce, Ted M. Ross · 2018 · ImmunoHorizons
The use of cell-mediated immunity for the evaluation of influenza vaccines: an upcoming necessity
Elena Gianchecchi, Alessandro Torelli, Emanuele Montomoli · 2019 · Human Vaccines & Immunotherapeutics
Antiviral Functions of Monoclonal Antibodies against Chikungunya Virus
Jing Jin, Graham Simmons · 2019 · Viruses
New antibody-based prevention and treatment options for influenza
Koen Sedeyn, Xavier Saelens · 2019 · Antiviral Research
A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice
Carly M. Bliss, Alec W. Freyn, Tom G. Caniels, Victor Hugo Leyva-Grado, Raffael Nachbagauer, Weina Sun, Gene S. Tan, Virginia Gillespie, Meagan McMahon, Florian Krammer et al. · 2022 · Molecular Therapy
Fc-Mediated Functions of Porcine IgG Subclasses
Basudev Paudyal, William N. Mwangi, Pramila Rijal, John C. Schwartz, Alistair Noble, Andrew E. Shaw, Joshua E. Sealy, Marie Bonnet‐Di Placido, Simon Paul Graham, Alain Townsend et al. · 2022 · Frontiers in Immunology
Primary Human Influenza B Virus Infection Induces Cross-Lineage Hemagglutinin Stalk–Specific Antibodies Mediating Antibody-Dependent Cellular Cytoxicity
de Vries, Rory D, Nieuwkoop, Nella J, van der Klis, Fiona R M, Koopmans, Marion P G, Krammer, Florian, Rimmelzwaan, Guus F · 2018 · The Journal of Infectious Diseases
Polycationic HA/CpG Nanoparticles Induce Cross-Protective Influenza Immunity in Mice
Chunhong Dong, Ye Wang, Wandi Zhu, Yao Ma, Joo Hee Kim, Lai Wei, Gilbert X. Gonzalez, Bao‐Zhong Wang · 2022 · ACS Applied Materials & Interfaces
Nanoparticle-based B-cell targeting vaccines: Tailoring of humoral immune responses by functionalization with different TLR-ligands
Claudia Zilker, Diana Kozlova, Viktoriya Sokolova, Huimin Yan, Matthias Epple, Klaus Überla, Vladimir Temchura · 2016 · Nanomedicine Nanotechnology Biology and Medicine
Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response
Susan Zolla‐Pazner, Rebecca L. R. Powell, Sara Yahyaei, Constance A. U. Williams, Xunqing Jiang, Wei Li, Shan Lu, Shixia Wang, Chitra Upadhyay, Catarina E. Hioe et al. · 2016 · Journal of Virology
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms
Adam McNee, Trevor R.F. Smith, Barbara Holzer, Becky Clark, Emily Bessell, Ghiabe-Henri Guibinga, Heather Brown, Katherine Schultheis, Paul D. Fisher, Stephanie J. Ramos et al. · 2020 · The Journal of Immunology
Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses
Lucas J. Kerstetter, Stephen Buckley, Carly M. Bliss, Lynda Coughlan · 2021 · Frontiers in Immunology
Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design
Carolin Loos, Margherita Coccia, Arnaud M. Didierlaurent, Ahmed Essaghir, Jonathan K. Fallon, Douglas A. Lauffenburger, Corinne Luedemann, Ashlin R. Michell, Robbert G. Van der Most, Alex Lee Zhu et al. · 2023 · npj Vaccines
The role of HIV-specific antibody-dependent cellular cytotoxicity in HIV prevention and the influence of the HIV-1 Vpu protein
Marit Kramski, Ivan Stratov, Stephen John Kent · 2014 · AIDS
Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge
Raffael Nachbagauer, David A. Shore, Hua Yang, Scott K. Johnson, Jon D. Gabbard, Stephen Mark Tompkins, Jens Wrammert, Patrick C. Wilson, James Stevens, Rafi Ahmed et al. · 2018 · Journal of Virology