An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation

Souroullas, George P, Jeck, William R, Parker, Joel S, Simon, Jeremy M, Liu, Jie-Yu, Paulk, Joshiawa, Xiong, Jessie, Clark, Kelly S +5 more·2016·Nature Medicine
DOI 10.1038/nm.4092

Cited by (212)

Items 201–212 of 212

  1. Unfolding the role of HDAC2 in the epigenetic puzzle of cancer: A dive into molecular pathways for precision-driven multi-target therapy
    Kakali Sarkar, Maria Debbarma, Shayanika Debnath, Sudhan Debnath, Samir Kumar Sil · 2025 · Biochemical Pharmacology
  2. Additional file 1 of A tumor suppressor role for EZH2 in diffuse midline glioma pathogenesis
    Swati Dhar, Samantha Gadd, Patel, Priyam, Jake Vaynshteyn, Raju, G. Praveen, Rintaro Hashizume, Daniel J. Brat, Oren Josh Becher · 2022 · Figshare
  3. Additional file 1 of Calcitonin gene-related peptide regulates spinal microglial activation through the histone H3 lysine 27 trimethylation via enhancer of zeste homolog-2 in rats with neuropathic pain
    An, Qi, Chenyan Sun, Ruidi Li, Chen, Shuhui, Gu, Xinpei, An, Shuhong, Wang, Zhaojin · 2021 · Figshare
  4. H3K27me3-dependent imprinting and transcriptional regulation in early mouse embryos requires EZHIP-mediated restriction of PRC2 activity
    Seynabou Diop, Laia Richart, Ambre Petitalot, Juliette Boni, Corentin Mollier, Batuhan Altay, Aurélien Dauphin, Virginie Raynal, Jean‐Léon Maître, Katia Ancelin et al. · 2026 · Nature Communications
  5. Rôle de l’oncoprotéine CBFβ-SMMHC dans la régulation génétique et épigénétique
    Gaëlle Cordonnier · 2017 · theses.fr (ABES)
  6. Repurposing acetyldigitoxin as a potential EZH2 inhibitor for non-small cell lung cancer: a computational and experimental approach
    Xiang Ji, Xiyan Wang, Ting Xiu, Min Gao, Degan Lu · 2026 · Journal of Computer-Aided Molecular Design
  7. Rôle de c-Jun dans la réponse aux inhibiteurs de la voie des MAPK dans les mélanomes
    Magdalena Pohorecka · 2018 · theses.fr (ABES)
  8. How Somatic Mutations cause Aging without Causing Aging
    Alexander Martin Wolf · 2026 · SSRN Electronic Journal
  9. Modélisation de la réponse thérapeutique du lymphome folliculaire grâce à un modèle 3D organoïde
    Narimène Houmera · 2023
  10. Mouse models of B cell lymphomas on the basis of genetic features
    Min Yuan, James Q. Wang · 2026 · Frontiers in Immunology
  11. Altered chromatin signaling in cancer
    Yusuke Okuda, Andrew Scott Liss · 2026 · Elsevier eBooks
  12. BindingDB Entry 50022486: Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor.
    BindingDB · 2025 · UC San Diego