Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation

Back, Stephen A, Tuohy, Therese M F, Chen, Hanqin, Wallingford, Nicholas, Craig, Andrew, Struve, Jaime, Luo, Ning Ling, Banine, Fatima +6 more·2005·Nature Medicine
DOI 10.1038/nm1279

Cited by (612)

Items 501–600 of 612

  1. Developmental regulation of zinc homeostasis in differentiating oligodendrocytes
    Christopher M. Elitt, Madeline M. Ross, Jianlin Wang, Christoph J. Fahrni, Paul A. Rosenberg · 2024 · Neuroscience Letters
  2. Brain Injury in the Preterm Infant
    Stephen A. Back, Steven Paul Miller · 2018 · Elsevier eBooks
  3. Impact of prenatal immune challenge on the demyelination injury during adulthood
    Abdeslam Mouihate, Hessah Al‐Hashash, S Rakhshani-Moghadam, Samah Kalakh · 2017 · CNS Neuroscience & Therapeutics
  4. Preterm birth: A neuroinflammatory origin for metabolic diseases?
    Sihao Diao, Chao Chen, Alexandre Bénani, Chr̀istophe Magnan, Juliette Van Steenwinckel, Pierre Gressèns, Céline Cruciani‐Guglielmacci, Alice Jacquens, Cindy Bokobza · 2024 · Brain Behavior & Immunity - Health
  5. The role of type I collagen in white matter injury
    Reiji Yamazaki, Nobuhiko Ohno · 2025 · Anatomical Science International
  6. Understanding water structure and organization in the convergence of biomaterial science and matrix biology
    Sacha Cavelier, Dietmar Werner Hutmacher · 2026 · Cell Biomaterials
  7. Developing drugs that promote remyelination: Is our in vitro screening approach too simplistic?
    DENNIS N. BOURDETTE, Lindsey Wooliscroft · 2024 · Neurotherapeutics
  8. Infantile cerebral palsy as a result of prenatal brain dysontogenesis
    Сальков Владимир Николаевич, Р. М. Худоерков · 2019 · Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
  9. Unexpected Remyelination in the Absence of Matrix Metalloproteinase 7
    Rianne Petra Gorter, Andrea J. Arreguin, Wendy Oost, Jenny C. de Jonge, Harm H. Kampinga, Sandra Amor, Holly Colognato, Wia Baron · 2025 · Glia
  10. Emerging Therapeutic Role of Chondroitinase (ChABC) in Neurological Disorders and Cancer
    Kiran Kumar Kolathur, Akshara Kumar, Aishi Biswas, Sree Lalitha Bojja, Volety Mallikarjuna Subrahmanyam · 2022 · Current Drug Therapy
  11. White Matter Repair in Subcortical Stroke
    Elif G. Sözmen, Stanley Thomas Carmichael · 2013 · Springer eBooks
  12. Melittin and hyaluronidase compound derived from bee venom for the treatment of multiple sclerosis
    Nazaninalsadat Seyed Khoei, Sina Atashpaz, Kamyar Ghabili, Nazlisadat Seyed Khoei, Yadollah Omidi · 2009
  13. Pathophysiology of Neonatal White Matter Injury
    Steven Paul Miller, Stephen A. Back · 2016 · Elsevier eBooks
  14. Neural Stem Cell Approaches to CNS Repair
    Nan Dai, Virginie Sottile · 2008 · Electronic journal of biology
  15. Cerebral Palsy
    Harvey S. Singer, Jonathan W. Mink, Donald L. Gilbert, Joseph J. Jankovic · 2010 · Elsevier eBooks
  16. Role of Immune Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
    Sarah Dhaiban, Mena Al‐Ani, Noha Mousaad Elemam, Mahmood H Al-Aawad, Zeinab Al-Rawi, Azzam A. Maghazachi · 2020 · Preprints.org
  17. Targeting astrocytic CLC2(CLCN2) restores myelin regeneration through inhibition of SPP1/CD44 signaling pathway in leukoencephalopathy
    Lu Yang, Yubao Lu, Jia Liu, Fan Zhu, Ying Jiang, Tingting Lu, Xiufeng Zhong, Wei Qiu, Changyong Tang, Fuhua Peng · 2025 · Molecular Psychiatry
  18. FOXO3 involvement in neurological OxInflammation
    Malak Alghamdi, Laura Gemmo, Anna Guiotto, Alessandra Pecorelli, Giuseppe Valacchi · 2026 · Redox Experimental Medicine
  19. Mechanisms of Plasticity Remodeling and Recovery
    Zhitong Zheng, Jieli Chen, Michael Chopp · 2021 · Elsevier eBooks
  20. Pathophysiology of Hypoxic-Ischemic Brain Injury
    Patrick S. McQuillen, Susan J. Vannucci, Henrik Hagberg · 2016 · Elsevier eBooks
  21. Hyaluronidases as Targets for the Treatment of Neurological Diseases
    Larry S. Sherman, Barbara A. Sorg, Steven G. Matsumoto, Weiping Su, Fatima Banine, Stephen A. Back · 2025 · Proteoglycan Research
  22. Exogenous Cell Myelin Repair and Neuroprotection in Multiple Sclerosis
    Ian D. Duncan, Yoichi Kondo · 2012 · Springer eBooks
  23. Role of Toll-Like Receptor 4 in Alcohol-Induced Neuroinflammation and Behavioral Dysfunctions
    Consuelo Guerri, María Pascual · 2012 · Springer eBooks
  24. Deciphering the Molecular and Cellular Basis for Dissemination of Diffuse Low-Grade Gliomas
    Zahra Hassani, Jean‐Philippe Hugnot · 2013 · Springer eBooks
  25. Pathophysiology: General Principles
    Alistair Jan Gunn, Joanne O. Davidson, Terrie Eleanor Inder, Joseph J. Volpe · 2024 · Elsevier eBooks
  26. INFLUENCE OF POTASSIUM HYALURONATE ON THE CHANGE OF PHOSPHOLIPASE ACTIVITY AND STATE OF THE MEMBRANES OF DAMAGED SOMATIC NERVES OF RATS
    В. В. Ревин, Marina Vladimirovna Isakina, Sergey Ivanovich Pinyaev, Nadezhda Victorovna Revina, А. А. Морозова · 2015 · International Journal of Pharma and Bio Sciences
  27. Roles of Macrophages and Astrocytes in Pathogenesis of Multiple Sclerosis
    Shyamal C. Bir, Oleg Y. Chernyshev, Alireza Minagar · 2018 · Elsevier eBooks
  28. Signaling pathways that regulate glial development and early migration—oligodendrocytes
    Stephen P.J. Fancy, Robert H. Miller · 2020 · Elsevier eBooks
  29. The CEMIP Hyaluronidase is Elevated in Oligodendrocyte Progenitor Cells and Inhibits Oligodendrocyte Maturation
    Alec Peters, Kanon Yasuhara, Weiping Su, Steven G. Matsumoto, Peter T. Pham, Fatima Banine, Eliana Harris, Stephen A. Back, Larry S. Sherman · 2025 · ASN NEURO
  30. Oligodendrocytes at the crossroads: Central players and interactive partners in white matter aging
    Xinxin Zhang, Peiyao Yu, Yicheng Chen, Yanzhi Xu, Ruofei Xu, Xinyu Yang, Shichao Lv, Hongcai Shang, Yue Hu · 2026 · Ageing Research Reviews
  31. Impact of the Chronic Ischemic Stroke Microenvironment on Silk Fibroin Hydrogel Biodegradation and De Novo Tissue Formation
    Suttinee Phuagkhaopong, Natalia Gorenkova, Panicha Aruvornlop, Hilary V. O. Carswell, F. Philipp Seib · 2026 · ACS Omega
  32. CD44 Expression Dynamics in the Corpus Callosum After Cuprizone-Induced Demyelination
    Lyubomir Gaydarski, K. Petrova, G.P. Georgiev, Pavel Rashev, Ivanka Kostadinova · 2026 · Acta Medica Bulgarica
  33. Signaling Pathways that Regulate Glial Development and Early Migration – Oligodendrocytes
    R. H. Miller · 2013 · Elsevier eBooks
  34. Neural Stem Cells and Demyelinating Disease
    Abbe Harper Crawford, Robin J.M. Franklin · 2014 · Stem cell biology and regenerative medicine
  35. Effects of Hyaluronan Tetrasaccharide on the Differentiation of Neuronal Cells and Oligodendrocyte Precursor Cells
    Hiroko Yamanokuchi · 2012 · THE JOURNAL OF THE STOMATOLOGICAL SOCIETY JAPAN
  36. Development of Oligodendrocytes in the Vertebrate CNS
    Robert H. Miller · 2012 · Springer eBooks
  37. Stressed Astrocytes: Insights on the Pathology of Alexander Disease
    Eileen Guilfoyle · 2013
  38. Mechanisms Underlying the Selective Vulnerability of Developing Human White Matter
    Paul A. Rosenberg · 2013 · Springer eBooks
  39. Endogenous Neural stem Cells and Neurological Disorders
    Madhav Rayate · 2017 · Open access Journal of Neurology & Neurosurgery
  40. Cerebral Palsy
    Harvey S. Singer, Jonathan W. Mink, Donald L. Gilbert, Joseph J. Jankovic · 2015 · Elsevier eBooks
  41. Autoimmune Astrocytopathy
    Jorge Daniel Correale, María Inés Gaitán · 2019 · Contemporary clinical neuroscience
  42. Cerebral Palsy
    Harvey S. Singer, Jonathan W. Mink, Donald L. Gilbert, Joseph J. Jankovic · 2022 · Elsevier eBooks
  43. Stem Cell Transplantation Combined with Niche Modification:A Novel Strategy for Treatment of Neurodegeneration
    Keiko Nakanishi, Atsuhiko Oohira · 2008
  44. Damage and Repair in Experimental Cortical Demyelination
    Enrique Garea‐Rodríguez · 2010
  45. The cuprizone model and multiple sclerosis : disparities and similarities
    Markus Kipp, Werner Baumgärtner · 2011 · RWTH Publications (RWTH Aachen)
  46. Vorkommen und Verteilung von Hyaluronan im normalen Gehirn und bei Hirnödem
    Marian Schmidt-Belden · 2011
  47. Neurofilament Changes in Multiple Sclerosis
    Elizabeth Gray, Alastair Wilkins · 2010 · Advances in neurobiology
  48. Functional implications of demyelination and the molecular control of remyelination in the adult mouse.
    Nicholas J. Kuypers · 2014
  49. Nörolojik Hastalıklarda Kök Hücre Nakli
    M. Özlem Hergüner · 2014 · Arşiv Kaynak Tarama Dergisi
  50. Spinal progenitor cell differentiation in collagen-based hydrogels: Directing oligodendrocyte differentiation using ECM signals
    A. Sydney, Alexandra L. Sabin, Christine E. Schmidt · 2014 · IEEE Annual Northeast Bioengineering Conference (NEBEC)
  51. Neuron–Oligodendrocyte Interactions in Neuroinflammation
    Kazuhiro Ikenaka · 2013 · Advances in neurobiology
  52. Low molecular weight hyaluronic acid increases CD44 expression by oligodendrocytes and enhances inflammation
    Susannah W. Kassler · 2006
  53. Mechanisms of Plasticity, Remodeling and Recovery
    Zheng Gang Zhang, Michael Chopp · 2015 · Elsevier eBooks
  54. Nonhematopoietic Effects of Erythropoietin
    Christopher Michael Traudt, Sandra E. Juul · 2012 · Elsevier eBooks
  55. Region specific characterization of the cuprizone model for Multiple Sclerosis and impairment of remyelination by corticosteroids
    Tim Clarner, Cordian Beyer · 2011 · RWTH Publications (RWTH Aachen)
  56. Dissemination of Diffuse Low-Grade Gliomas: Tools and Molecular Insights
    Nicolas Leventoux, Zahra Hassani, Jean‐Philippe Hugnot · 2017 · Springer eBooks
  57. Effects of PH20 Hyaluronidase Inhibition In Vivo Following Cerebral White Matter Injury
    Rachel E. Siltman · 2017
  58. On the role of macrophages, microglia and the extracellular matrix in remyelination
    Peng Wang · 2018 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  59. Aspectos científicos, técnicos y éticos de la terepia celular y medicina regenerativa = Scientific, technical and ethical aspects of Cell Therapy and Regenerative Medicine
    Jorge Estopà Dueso · 2013
  60. Remyelination in Multiple Sclerosis
    Shyamal C. Bir, Oleg Y. Chernyshev, Alireza Minagar · 2018 · Elsevier eBooks
  61. The glycosyltransferase EXTL2 and its regulation of remyelination and neuroinflammation
    Yu Pu · 2019
  62. Remyélinisation du système nerveux central et sclérose en plaques
    Anne‐Laure Dubessy, Bruno Stankoff · 2019 · Elsevier eBooks
  63. Pharmacokinetics of melatonin as a neuroprotectant In preterm infants
    Nazakat M. Merchant · 2013 · Spiral (Imperial College London)
  64. Glycan-Related Demyelination and Remyelination
    Shinobu Kitazume · 2020 · Elsevier eBooks
  65. Investigation of myelin maintenance and turnover by inducible MBP knock-out in adult mice
    Martin Meschkat · 2019
  66. Gliovascular Mechanisms and White Matter Injury in Vascular Cognitive Impairment and Dementia
    Gary A. Rosenberg, Takakuni Maki, Ken Arai, Eng H. Lo · 2021 · Elsevier eBooks
  67. Oligodendrozytenpopulationen in Läsionen der multiplen Sklerose sowie der toxisch- und autoimmun-induzierten Demyelinisierung
    Raein Kordestani Nejad · 2021
  68. Faculty Opinions recommendation of Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology.
    Azad Bonni, Yoshiho Ikeuchi · 2009 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  69. Faculty Opinions recommendation of Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis.
    Roland Martinꝉ · 2009 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  70. Faculty Opinions recommendation of Remyelination Alters the Pattern of Myelin in the Cerebral Cortex.
    David Anthony Lyons, Rafael Almeida · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  71. Neuroinflammation in Multiple Sclerosis
    Pranathi Prasad, Larissa Roth, Rosana-Bristena Ionescu, Cory M. Willis, Alexandra M. Nicaise, Grzegorz Krzak, Luca Peruzzotti‐Jametti, Stefano Pluchino · 2022 · Elsevier eBooks
  72. Immunoblot Investigation of Aggrecan Protein in Post-mortem Brain Tissue
    Abuneeza Esadawi, Nicola Woodroof, Emad Mohamed ELzian · 2022 · Sirte Journal of Medical Sciences
  73. Carbohydrates and human glycosylation
    Anup Mammen Oommen, Satbir Kaur Gill, Lokesh Joshi, Stephen Cunningham · 2024 · Elsevier eBooks
  74. Autoimmune Astrocytopathy
    Jorge Daniel Correale, Mariano Marrodán · 2024 · Springer eBooks
  75. The Extracellular Matrix as a Target for Biophysical and Molecular Magnetic Resonance Imaging
    Angela Ariza de Schellenberger, Judith W. J. Bergs, Ingolf Sack, Matthias Taupitz · 2024 · Springer eBooks
  76. Autoimmune Astrocytopathy
    Jorge Daniel Correale, Mariano Marrodán · 2024 · Springer eBooks
  77. Nanoimaging in Neurology
    Sikandar Shaikh · 2024 · Springer eBooks
  78. Viral-mediated fluorescent labeling of hyaluronan reveals extracellular matrix dynamics in the mouse brain in vivo
    Mario Fernandez-Ballester, María Ardaya, Nathalie Dutheil, Leslie-Ann Largitte, Abraham Martín, Federico Nicolás Soria · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  79. Additional file 6 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  80. Additional file 4 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  81. Additional file 3 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  82. Additional file 5 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  83. Additional file 7 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  84. Additional file 2 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  85. Additional file 1 of Human post-mortem organotypic brain slice cultures: a tool to study pathomechanisms and test therapies
    Bonnie C. Plug, Ilma M. Revers, Marjolein Breur, González, Gema Muñoz, Jaap A. Timmerman, Niels Meijns, Daniek Hamberg, Jikke Wagendorp, Erik Nutma, Nicole I. Wolf et al. · 2024 · Figshare
  86. Identification de programmes d'activation macrophagique et microgliale dans les formes progressives de la sclérose en plaques
    Alice Lhuillier · 2014 · theses.fr (ABES)
  87. The Pathological role of DCIR in Autoimmune Encephalomyelitis in mice
    彬正 妹尾 · 2015 · Institutional Repositories DataBase (IRDB)
  88. Neural Stem Cells in Demyelinating Diseases: Interplay Between Lineage Potential and the Microenvironmental Constraints in Remyelination
    Agustín Jesús Byrne, Matías Arturo Pibuel, Juan Manuel Lázaro Martínez, Paula Gabriela Franco · 2026 · Journal of Neurochemistry
  89. Etude des mécanismes sous-tendant la récupération fonctionnelle post-AVC associée à la transplantation différée de cellules hADSC exprimant le neuropeptide PACAP.
    Roxane Gruel · 2019 · theses.fr (ABES)
  90. Identification des facteurs oligodendrogliaux sécrétés impliqués dans la formation des Nœuds de Ranvier du Système Nerveux Central
    Anne‐Laure Dubessy · 2018
  91. Le cil primaire : une nouvelle cible pour la remyélinisation ?
    Giada Delfino · 2020 · theses.fr (ABES)
  92. Mécanismes moléculaires et cellulaires impliqués dans la production de la myéline induite par les voies de signalisation Hedgehog et des androgènes dans le système nerveux central
    Abdelmoumen Kassoussi · 2021 · theses.fr (ABES)
  93. Etude des conséquences des altérations de la myéline sur les fonctions cognitives à la suite d’un épisode transitoire de démyélinisation chez la souris adulte
    Océane Mercier · 2022 · theses.fr (ABES)
  94. Rôle inattendu de la signalisation des androgènes dans le système nerveux central démyélinisé de la souris femelle : Identification de spécificités liées au sexe de l'animal
    Amina Zahaf · 2022 · theses.fr (ABES)
  95. Contribution des neuroblastes dérivés de la zone sous ventriculaire à la régénération de la myéline dans le cerveau de souris adulte : impact des propriétés mécaniques des tissus
    Marie Falque · 2023 · theses.fr (ABES)
  96. Post-ischemic modification of neurogenesis and oligodendrogenesis in rodent models
    Yoshihide Sehara, Shinya Mochizuki, Reiji Yamazaki · 2026 · Frontiers in Neural Circuits
  97. Microenvironmental Regulation of Central Nervous System Myelination and Remyelination
    Yuxuan Wang, Lingzhen Tan, Lin Lao, Xiaomeng Huang, Sheng Zhang, Sun H · 2026 · Journal of Integrative Neuroscience
  98. Naive CD4+ T cells synthesize a hyaluronan-rich glycocalyx that is diminished following activation
    Laxmi Prasad Adhikari, Jessica Contreras, Kristen M. Patterson, Meghan M. Moran, Erin N. Howe, Anna Plaas, Joseph M. Reynolds · 2026 · iScience
  99. Heparan sulfate and glycomimetics: Advances in synthesis and biological applications for post‐stroke neurorepair
    Mozammel Haque Bhuiyan, Madeleine J. Smith, Simon F.R. Hinkley, Andrew N. Clarkson · 2026 · Neuroprotection/Neuroprotection (Chichester, England. Print)
  100. CD44 as a Conserved Biomarker and Functional Modulator of Neuroinflammation in Multiple Sclerosis and Beyond
    Newshan Behrangi, Maria-Sophia Stadler, Christin Reinbach, Luisa Burkert, Alexander Hawlitschka, Hannes Kaddatz, Lukas Wenzel, Gemma Llovera, Andreas Wree, Chloé Hoornaert et al. · 2026 · Molecular Neurobiology