The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

Tsai, Yien Che, Mendoza, Arnulfo, Mariano, Jennifer M, Zhou, Ming, Kostova, Zlatka, Chen, Bo, Veenstra, Timothy, Hewitt, Stephen M +3 more·2007·Nature Medicine

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  80. b) Corresponding Author
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