Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

Tebbutt, Niall C., Giraud, Andrew S., Inglese, Melissa, Jenkins, Brendan, Waring, Paul, Clay, Fiona J., Malki, Sina, Alderman, Barbara M. +4 more·2002·Nature Medicine

Cited by (469)

Items 401–469 of 469

  1. Role of the intracellular receptor domain of gp130 (exon 17) in human inflammatory bowel disease
    C.J. Auernhammer · 2005 · World Journal of Gastroenterology
  2. Review article: regulation of TFF1 (pS2) expression in gastric epithelial cells
    Y. FUJII, Tadahito Shimada, T Koike, K. Hosaka, Kaoru Tabei, Takashi Namatame, Akihiro Tajima, Masashi Yoneda, Akira Terano, H. Hiraishi · 2006 · Alimentary Pharmacology & Therapeutics Symposium Series
  3. The STAT3 Pathway and Downstream Mechanisms in Cardiac Remodeling: Friend or Foe
    Melanie Ricke‐Hoch, Britta Stapel, I. A. Gorst, Arash Haghikia, Denise Hilfiker‐Kleiner · 2013 · Springer eBooks
  4. Investigating the Role of Toll-Like Receptors in Mouse Models of Gastric Cancer
    Alison C. West, Brendan John Jenkins · 2016 · Methods in molecular biology
  5. Mechanisms of Helicobacter pylori-induced Gastric Inflammation
    Dawn A. Israel, Richard M. Peek · 2012 · Elsevier eBooks
  6. Genetically engineered mouse models in gastric precancerous lesions research
    Yi Quan, Yue-Bo Jia, Chen-Heng Wu, Qingling Jia, Yong-Qi Chen, GU Zhi-Jian, Jianghong Ling · 2025 · World Journal of Gastrointestinal Surgery
  7. Receptor engineering constitutes feedback control and robustness of IL-23R signaling and highlights importance of intracellular cytokine receptor signaling motifs
    Leorina Kashtanjeva, Christin Ruhland, F. C. Horstmeier, Felix Thives-Kurenbach, Julia Ettich, Giacomo Padrini, Sophie Streuber, Jürgen Scheller, Anna Dittrich, Doreen Manuela Floss · 2026 · Cell Communication and Signaling
  8. Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-in mice does not alter hematopoietic stem cell repopulation or self-renewal potential.
    Zhengqi Wang, Zizhen Kang, Yi Zhang, William Tse, Kevin D. Bunting · 2012 · Europe PMC (PubMed Central)
  9. IL-11 mediated Stat3 activation in inflammation and cancer
    Tracy L. Putoczki, Stefan Thiem, Andrew Jarnicki, Brent S. McKenzie, Stefan Rose‐John, Matthias Ernst · 2009 · Cytokine
  10. Helicobacter pylori cytotoxin-associated gene A virulence and its association with the epithelial-mesenchymal transition in gastric cancer
    Iga Dudek, Alicja Forma, Justyna Hamerska, Michał Flieger, Jacek Januszewski, Tomasz Cywka, Joanna Kozak, Jacek Baj · 2022 · Journal of Education Health and Sport
  11. Review article: regulation of TFF1 (pS2) expression in gastric epithelial cells
    Y. FUJII, Tadahito Shimada, T Koike, K. Hosaka, Kaoru Tabei, Takashi Namatame, Akihiro Tajima, Masashi Yoneda, Akira Terano, H. Hiraishi · 2006 · Alimentary Pharmacology & Therapeutics
  12. Cancer Genetics of Human Gastric Adenocarcinoma
    Roman Galysh, Steven M. Powell · 2009 · Springer eBooks
  13. The AGA/Funderburg Award in Gastric Cancer: Twenty-five Years of Advances in Gastric Cancer Research
    James R. Goldenring · 2017 · Gastroenterology
  14. The role of TLRs (microbe recognition receptor) in gastric cancer: An update
    Saade Abdalkareem Jasim, Sumaya Ayad Abdulrazzaq, H. Malathi, Suhaib Iqbal, Gaurav V. Sanghvi, E. Yulchiev, Subhashree Ray, S. Sunitha, Jawad Kadhim Ahmed, Ahmed Hussein Zwamel · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  15. The combined effect of IL-6 and hypoxia increases KLK4 gene expression in colon cancer cells via STAT-3 activation
    Fatma Poyrazlı, Sümeyye Aydoğan Türkoğlu · 2025 · Cytotechnology
  16. Growth Impairment in Pediatric Inflammatory Bowel Disease
    Thomas D. Walters, Anne Marie Griffiths · 2017 · Springer eBooks
  17. A (selective) history of Australian involvement in cytokine biology
    Nicos Anthony Nicola · 2013 · Cytokine & Growth Factor Reviews
  18. Inflammatory Mediators in Tumorigenesis and Metastasis
    Jeremy Dupaul-Chicoine, Maya Saleh · 2013 · Springer eBooks
  19. Astrocyte‐intrinsic regulation of central nervous system inflammation and neurodegeneration
    Veit Rothhammer, Francisco Javier Quintana · 2016 · Clinical and Experimental Neuroimmunology
  20. Research advancements and evaluation of multifactor‐induced murine models for gastric cancer
    Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng · 2025 · Animal Models and Experimental Medicine
  21. Fonctions paradoxales pour TFF1
    Marie‐Christine Rio · 2002 · médecine/sciences
  22. STAT/SOCS Family Members in Inflammation and Diseases
    Akihiko Yoshimura, Ichiko Kinjyo, Kyoko Inagaki‐Ohara, Toshikatsu Hanada · 2003 · Springer eBooks
  23. Growth Impairment in Pediatric Inflammatory Bowel Disease
    James Guoxian Huang, Thomas D. Walters · 2023 · Springer eBooks
  24. Genetic Models of Gastric Cancer in the Mouse
    Andrew S. Giraud, Louise M. Judd · 2009 · Springer eBooks
  25. Mechanisms and Biological Roles of STAT Activation by the IL-6 Family of Cytokines
    Daisuke Kamimura, Toshio Hirano · 2003 · Springer eBooks
  26. Role of SOCS proteins during mycobacterial infections
    Berit Carow · 2012 · Figshare
  27. Post-translational Modifications in Regulation of Jak-stat Pathway
    Daniela Ungureanu · 2005 · Tampere University Institutional Repository (Tampere University)
  28. Novel matrix metalloproteinases in intestinal inflammation and in cancer of the gastrointestinal tract
    Ville Bister · 2007 · Työväentutkimus Vuosikirja
  29. Helicobacter pylori and Cytokines in the Genesis of Gastric Cancer
    Richard M. Peek · 2007 · Humana Press eBooks
  30. Host Immunity in the Development of Gastric Preneoplasia
    Peter B. Ernst, Mohammad Samiul Alam, Asima Bhattacharyya, Sheila Eileen Crowe · 2009 · Springer eBooks
  31. Prostaglandin and Transforming Growth Factor β Signaling in Gastric Cancer
    Masanobu Oshima, Hiroko Oshima, Makoto Mark Taketo · 2009 · Springer eBooks
  32. Innate Immunity, Inflammation and Colorectal Cancer
    Kepeng Wang, Sergei I. Grivennikov, Michael Karin · 2013 · Else Kröner-Fresenius Symposia
  33. The Molecular Mechanisms of Helicobacter pylori-Associated Gastroduodenal Disease
    Peter B. Ernst · 2007 · Humana Press eBooks
  34. The Role of Phosphatases and Reactive Oxygen Species in Regulation of the JAK/STAT Pathway
    Andrew C. Larner, Michael David · 2003 · Springer eBooks
  35. The Role of SOCS3 Signaling in Ulcerative Colitis and Ulcerative Colitis-related Carcinogenesis
    Yi Li · 2012 · EUR Research Repository (Erasmus University Rotterdam)
  36. Functional Analysis of Trefoil Factors 1 and 3 in Tumorigenesis
    Daniel R. Radiloff · 2009 · DukeSpace (Duke University)
  37. Virulence of Helicobacter pylori infection and gastric cancer: lessons from mouse models
    Timothy Cragin Wang, James G. Fox, JeanMarie Houghton · 2003 · Springer eBooks
  38. [Interosseous muscles of the rat].
    Erdal DENİZ · 1971 · PubMed
  39. The regulation of gp130 surface expression on monocytes : implications in chronic inflammation
    Nora Honke, P Idm, Rainer Fischer, Klaus Tenbrock · 2014 · RWTH Publications (RWTH Aachen)
  40. Reduction of MDR1, MRP1 and BCRP expression in Crohn’s disease: a role in disease pathogenesis?
    Ana Savić Mlakar, Žarko Babić, Branko Troskot, Mladen Jergović, Valerija Vojvoda Parčina, Željko Mihaljević, Krešo Bendelja · 2015 · Periodicum Biologorum
  41. Modulation of dendritic cell function through delivery of effector proteins by genetically modified lactococcus lactis
    Michaela Loos · 2007 · Ghent University Academic Bibliography (Ghent University)
  42. The Role of the Interleukin-6 Family of Cytokines in Bone Remodeling and Bone Cancer
    Frédéric Blanchard, Emmanuelle David, Bénédicte Brounais-Le Royer · 2010 · Elsevier eBooks
  43. Current state of the evolving MMMN cancer progression models of cancer
    Sam Thiagalingam · 2015 · Cambridge University Press eBooks
  44. inflammation from emphysema in gp130 mutant mice Deregulated Stat3 signaling dissociates pulmonary
    Brendan John Jenkins, Anthony Longano, Philip G. Bardin, Steven Bozinovski, M. Ruwanpura, Louise McLeod, Alistair Miller, Jessica E. C. Jones, Ross Vlahos · 2016
  45. Biology of human stomach cancer
    Bryan G. Sauer, Steven M. Powell · 2015 · Cambridge University Press eBooks
  46. TLR4-Dependent Inflammatory Responses IL-6 Trans-Signaling Modulates
    Brendan John Jenkins, Matthias Ernst, Paul J. Hertzog, Ashley S. Mansell, Claire Greenhill, Stefan Rose‐John · 2013
  47. The Role of Stat3 in Mouse Models of Inherited Photoreceptor Degeneration
    Ke Jiang · 2013 · TSpace (University of Toronto)
  48. Activation of STAT3 in Gastric Cancer Development
    Kishore Kumar Jella · 2017 · Springer eBooks
  49. Mechanisms of Helicobacter pylori–Induced Gastric Inflammation
    Dawn A. Israel, Richard M. Peek · 2006 · Elsevier eBooks
  50. A Limelight on Human Gp130 and Its Deleterious Mutations: A Computational Sequence Level Approach for Hepatocellular Carcinomas
    Shreya Bhattacharya, Debina Basu, Ritika Nandy, Arundhati Banerjee, Sujay Ray · 2021 · Lecture notes in networks and systems
  51. [Role of Helicobacter pylori virulence factors on induction of cytokines from gastric epithelial cells].
    Yoshio Yamaoka · 2004 · Nippon Saikingaku Zasshi
  52. The effects of digestion resistant carbohydrates on the colon microbiota and colon tissue transcriptome of weanling rats
    Wayne Young · 2011 · Otago University Research Archive (University of Otago)
  53. Assoziationen psychometrisch erfasster Parameter mit Markern der Immunaktivierung bei Patientinnen und Patienten mit depressiven Syndromen
    Katharina Annette von Knebel · 2022
  54. Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages
    Riley J. Morrow, Amr H. Allam, Joshua Konecnik, David Baloyan, Christine Dijkstra, Moritz F. Eissmann, Saumya P. Jacob, Megan O’Brien, Ashleigh R. Poh, Matthias Ernst · 2022 · Cells
  55. Data from A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
    Anna Wuestefeld, Viktoriia Iakovleva, Shirlyn Xue Ling Yap, Agnes Bee Leng Ong, Daniel Q. Huang, Timothy Wai Ho Shuen, Han Chong Toh, Yock Young Dan, Lars Zender, Torsten Wüestefeld · 2023
  56. IL-6 and IL-27 negatively regulate CRTAM-expressing CD4 + T-cells associated with lymphoid-driven synovitis
    Alicia Derrac Soria, Myles Lewis, Xiao Liu, Jason P. Twohig, Federica Monaco, Sandra Dimonte, Ana Cardus Figueras, Aisling S. Morrin, Carol Guy, Benjamin C. Cossins et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  57. The Role of IL-6 Trans-Signaling in the Pathogenesis of Perioperative Neurocognitive Disorders
    Odmara L. Barreto Chang, Harper S. Kim, Mervyn Maze · 2024 · Springer eBooks
  58. The Role of IL-6 Trans-Signaling in the Pathogenesis of Perioperative Neurocognitive Disorders
    Odmara L. Barreto Chang, Harper S. Kim, Mervyn Maze · 2025 · Springer eBooks
  59. Discrete cytokine signaling networks instruct distinct synovial pathotypes in inflammatory arthritis
    Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes, Reuben N. Scott, Ana Cardus Figueras, Sandra Dimonte, Daniela O. Costa, Ngoc‐Nga Vinh, Federica Monaco, Robert L. Jenkins et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  60. The Role Of C-Myb In Gastrointestinal Tract Development And Carcinogenesis
    Robert George Ramsay, Daniel Ciznadji, Gabriella Zupi · 2007 · Springer eBooks
  61. Modulating hypertrophic scar formation by targeting endothelial transient receptor potential vanilloid-1/nuclear factor kappa-B/interleukin-6 axis to regulate angiogenesis
    Hao Ma, Liuhanghang Cheng, Ruoyu Ling, J W Chen, Shunuo Zhang, Shujing Lin, Liang Ding, Chengliang Deng, Yixin Zhang, Peiru Min · 2026 · Burns & Trauma
  62. L'acide cinnamique régule l'expression post-transcriptionnellede la cyclooxygénase-2
    Noémie Legrand · 2012
  63. Genomic and Proteomic Advances in Gastric Cancer
    Alex Boussioutas, Patrick B. O. Tan · 2009 · Springer eBooks
  64. Caractérisation de la différenciation de l'endoderme primitif : Coopération entre la voie de signalisation RTK-FGF et le facteur de transcription Gata 6
    Stéphanie Hermitte · 2017
  65. Étude de la méthylation des gènes STAT3, IL2RA et CDH1 dans la maladie de Crohn iléale
    Solafah Abdalla · 2023 · theses.fr (ABES)
  66. Baseline salivary IL-6 as a predictive biomarker for complementary therapy response in radiation-induced oral mucositis
    Hsu-Chieh Chang, Yue-Wen Chen, Wen-Yen Huang, Jo‐Ting Tsai, Chia-Yu Wu, Made Satya Nugraha Gautama, Tsai‐Wei Huang · 2026 · European Archives of Oto-Rhino-Laryngology
  67. Hepatic origin of increased serum TFF3 in gastric cancer bearing subjects
    Komei Kuge, Junko MUKOYAMA, Yoshimi Yasukawa, Yuko Ishibashi, Hiroki Masuda, Tomohiko Yasuda, Yasukazu Ohmoto, Hideyuki Takeshima, Akihisa Matsuda, Hiroshi Yoshida et al. · 2026 · Gastric Cancer
  68. BindingDB Entry 50023362: STATs, promising targets for the treatment of autoimmune and inflammatory diseases.
    BindingDB · 2026 · UC San Diego
  69. Mouse models of gastric preneoplasia and cancer, with a focus on pathology
    Raymond Y. Ho, Yongji Zeng, Jason C. Mills · 2026 · Disease Models & Mechanisms