Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP

Di Salvio, Michela, Di Giovannantonio, Luca Giovanni, Acampora, Dario, Prosperi, Raffaele, Omodei, Daniela, Prakash, Nilima, Wurst, Wolfgang, Simeone, Antonio·2010·Nature Neuroscience

Cited by (118)

Items 101–118 of 118

  1. Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration
    Silas A. Buck, Sophie A. Rubin, Tenzin Kunkhyen, Christoph D. Treiber, Xiangning Xue, Lief E. Fenno, Samuel J. Mabry, Varun R. Sundar, Zilu Yang, Divia Shah et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  2. Binge-Like Ethanol Drinking Increases Otx2 , Wnt1 , and Mdk Gene Expression in the Ventral Tegmental Area of Adult Mice
    Cassandre Coles, Amy W. Lasek · 2021 · Neuroscience Insights
  3. The impact of Short Tandem Repeats on grey matter brain imaging derived phenotypes in UK Biobank
    William Sproviero, Upamanyu Ghose, Laura M. Winchester, Marco Fernandes, Danielle Newby, Daisy Sproviero, Najaf Amin, Bart Smets, Karen He, Ekaterina A. Khramtsova et al. · 2023 · medRxiv
  4. Distribution, connection and function of ALDH1A1+/TH+ neurons in substantia nigra pars reticulata of mouse
    Hao Liu, Zhuo Gong, Li Zhao, Tonglin Ye, Anqi Cao, Shuaiying He, Sijia Lin, Jinhai Duan, Xian Zhi Lin · 2023 · Neuroscience Letters
  5. Activating Wnt1/β-Catenin signaling pathway to restore Otx2 expression in the dopaminergic neurons of ventral midbrain
    Li Zhao, Jinhai Duan, AnQi Cao, Zhuo Gong, Hao Liu, Danyang Shen, Tonglin Ye, Shunyan Zhu, Qikai Cen, Shuaiying He et al. · 2025 · Experimental Neurology
  6. Tracing lineages to uncover neuronal identity
    Lia Panman, Thomas Perlmann · 2011 · BMC Biology
  7. Otx genes and seizure susceptibility
    2014 · Molecular & Cellular Epilepsy
  8. Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate
    Willemieke M. Kouwenhoven, Lars von Oerthel, Maria Gruppilo, Jianmin Tian, Cindy M. R. J. Wagemans, Imke G. J. Houwers, Joseph D. Locker, Simone Mesman, Marten P. Smidt · 2021 · International Journal of Molecular Sciences
  9. CELL REPLACEMENT THERAPY FOR PARKINSON’S DISEASE: The importance of neuronal subtype, cell source and connectivity for functional recovery
    Shane Grealish · 2012 · Lund University Publications (Lund University)
  10. C O M M E N TA R Y Open Access
    Lia Panman, Thomas Perlmann · 2011
  11. Non-cell autonomous OTX2 transcription factor regulates anxiety-related behaviors in the mouse
    Christine Vincent, Javier Gilabert‐Juan, Daniel Alvarez‐Fischer, Ariel A. Di Nardo, Marie‐Odile Krebs, Gwenaëlle Le Pen, Alain Prochiantz · 2019 · HAL
  12. Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
    Federico Miozzo, Luca Stickley, Eva P. Valencia-Alarcón, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Control of Neuronal Terminal Differentiation Through Cell Context-Dependent CFI-1/ARID3 Functions
    Yinan Li, Jayson J. Smith, Filipe Marques, Anthony Osuma, Hsin-Chiao Huang, Paschalis Kratsios · 2022 · SSRN Electronic Journal
  14. Molecular heterogeneity of midbrain dopamine neurons
    Rajeshwar Awatramani, Jean-Francois Poulin · 2025 · Handbook of behavioral neuroscience
  15. NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson’s disease models
    Eva P. Valencia-Alarcón, Lou C. Duret, Emi Kobayashi, Olivia Cattaneo, Bernard Laurent Schneider, Emi Nagoshi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Additional file 1 of Identification of sixteen novel candidate genes for late onset Parkinson’s disease
    Alessandro Gialluisi, Mafalda Giovanna Reccia, Nicola Modugno, Teresa Nutile, Alessia Lombardi, Luca Giovanni Di Giovannantonio, Sara Pietracupa, Daniela Ruggiero, Simona Scala, Stefano Gambardella et al. · 2021 · Figshare
  17. Molecular networks, structure, and function of the striatum during behavioural learning and automatization
    Eliana Lopes Rio da Silva Lousada · 2023
  18. Beyond the brain: a multisystem review of pathogenesis, comorbidity, and therapeutic progress in sporadic Parkinson’s disease
    Yang Li, Lijun Guo, Xiya Yu, Changgeng Peng · 2026 · Ageing and Neurodegenerative Diseases