Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults

Alvarez-Fischer, Daniel, Fuchs, Julia, Castagner, François, Stettler, Olivier, Massiani-Beaudoin, Olivia, Moya, Kenneth L, Bouillot, Colette, Oertel, Wolfgang H +5 more·2011·Nature Neuroscience

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  9. Homeoprotein ENGRAILED-1 promotes motoneuron survival and motor functions
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  10. Enhanced yield and subtype identity of hPSC-derived midbrain dopamine neuron by modulation of WNT and FGF18 signaling
    Tae Wan Kim, Jinghua Piao, Vittoria Dickinson Bocchi, So Yeon Koo, Se Joon Choi, Fayzan F. Chaudhry, Donghe Yang, Hyunwoo Cho, Emiliano Hergenreder, Lucia Ruiz Perera et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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  13. Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation
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  14. Ventral midbrain dopaminergic neurons: From neurogenesis to neurodegeneration
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  15. Post-transcriptional regulation of mitochondrial function
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  16. Genetic analysis of transcription factors in dopaminergic neuronal development in Parkinson's disease
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  17. Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed dopaminergic neurodegeneration
    Lautaro F. Belfiori-Carrasco, Alfredo Dueñas Rey, Dorottya Mária Ralbovszki, Itzia Jiménez-Ferrer, Filip Fredlund, Sagar Shivayogi Balikai, Dag Ahrén, Kajsa Atterling Brolin, Maria Swanberg · 2024 · Frontiers in Aging Neuroscience
  18. Regulation of complex I by Engrailed is complex too
    Laurie H. Sanders, J. Timothy Greenamyre · 2011 · Nature Neuroscience
  19. New transgenic models of Parkinson's disease using genome editing technology
    J.A. Cota-Coronado, S. Sandoval-Ávila, Y.P. Gaytan-Dávila, Néstor Fabián Díaz, Brenda Vega-Ruiz, Eduardo Padilla‐Camberos, N.E. Díaz-Martínez · 2019 · Neurología (English Edition)
  20. Heterozygous loss of Engrailed-1 and α-synucleinopathy (En1/SYN): A dual-hit preclinical mouse model of Parkinson's disease, analyzed with artificial intelligence
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  21. SerpinA3N inhibits mitochondrial complex I activity to prevent neuron ferroptosis following cerebral ischemic stroke
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  24. Engrailed1 in Parvalbumin‐Positive Neurons Regulates Eye‐Specific Retinogeniculate Segregation and Visual Function
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  25. Identification of a new, Rab14-dependent, endo-lysosomal pathway
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  26. Construction of a ceRNA network combining transcription factors in eutopic endometrial tissue of tubal factor infertility and endometriosis-related infertility
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  27. Nigral Transcriptomic Profiles in Engrailed-1 Hemizygous Mouse Models of Parkinson’s Disease Reveal Upregulation of Oxidative Phosphorylation-Related Genes Associated with Resistance to Dopaminergic Neurodegeneration
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  28. Mitochondrial Involvement in Neurodegeneration and Aging
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  29. Funktionelle Analyse des Transkriptionsfaktors Pitx3 während der Entwicklung dopaminerger Neuronen im murinen Mittelhirn
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  32. Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor
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  38. Embryonic dopaminergic neuron activity sustains lifelong locomotion in Drosophila
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  41. Interaction d’Engrailed avec des partenaires biologiques : FoxA2 et membranes lipidiques
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  42. Uncoupling tumorigenicity from dopaminergic differentiation potential of hiPSCs by acting on Glypican4 : combining in vitro differentiation studies with preclinical studies for Parkinson's disease therapy
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  45. Engrailed-1 potentiates mitochondrial transplant neuroprotection in spinal cord ischemia-reperfusion injury
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  46. Engrailed, a target of the miR-92 family, attenuates Tau accumulation and associated memory deficits in Drosophila
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  48. Embryonic dopaminergic neuron activity sustains lifelong locomotion in Drosophila
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  49. Engrailed-1 in eccrine sweat gland development and regeneration: from evolutionary innovation to therapeutic perspectives
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