Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults
Alvarez-Fischer, Daniel, Fuchs, Julia, Castagner, François, Stettler, Olivier, Massiani-Beaudoin, Olivia, Moya, Kenneth L, Bouillot, Colette, Oertel, Wolfgang H +5 more·2011·Nature Neuroscience
DOI 10.1038/nn.2916
Cited by (149)
Items 101–149 of 149
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- Enhanced yield and subtype identity of hPSC-derived midbrain dopamine neuron by modulation of WNT and FGF18 signalingTae Wan Kim, Jinghua Piao, Vittoria Dickinson Bocchi, So Yeon Koo, Se Joon Choi, Fayzan F. Chaudhry, Donghe Yang, Hyunwoo Cho, Emiliano Hergenreder, Lucia Ruiz Perera et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- Ventral midbrain dopaminergic neurons: From neurogenesis to neurodegenerationEric Jinsheng Huang · 2015 · FEBS Letters
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- Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed dopaminergic neurodegenerationLautaro F. Belfiori-Carrasco, Alfredo Dueñas Rey, Dorottya Mária Ralbovszki, Itzia Jiménez-Ferrer, Filip Fredlund, Sagar Shivayogi Balikai, Dag Ahrén, Kajsa Atterling Brolin, Maria Swanberg · 2024 · Frontiers in Aging Neuroscience
- Regulation of complex I by Engrailed is complex tooLaurie H. Sanders, J. Timothy Greenamyre · 2011 · Nature Neuroscience
- New transgenic models of Parkinson's disease using genome editing technologyJ.A. Cota-Coronado, S. Sandoval-Ávila, Y.P. Gaytan-Dávila, Néstor Fabián Díaz, Brenda Vega-Ruiz, Eduardo Padilla‐Camberos, N.E. Díaz-Martínez · 2019 · Neurología (English Edition)
- Heterozygous loss of Engrailed-1 and α-synucleinopathy (En1/SYN): A dual-hit preclinical mouse model of Parkinson's disease, analyzed with artificial intelligenceLucas A. Stetzik, Gabriela Mercado, Jennifer A. Steiner, Allison Lindquist, Carla Gilliland, Emily Schulz, Lindsay K. Meyerdirk, Lindsey Smith, Jeremy Molina, Darren J. Moore · 2024 · Neurobiology of Disease
- SerpinA3N inhibits mitochondrial complex I activity to prevent neuron ferroptosis following cerebral ischemic strokeXiansheng Liu, Gan Li, Yunlu Guo, Ruqi Li, Shilin Yi, Shenghao Ding, Jieqing Wan · 2025 · Experimental Neurology
- Otx genes and seizure susceptibility2014 · Molecular & Cellular Epilepsy
- Cerox1 and microRNA-488-3p noncoding RNAs jointly regulate mitochondrial complex I catalytic activityTamara Sirey, Kenny Roberts, Wilfried Haerty, Oscar C. Bedoya-Reina, Sebastian Rogatti, Jennifer Y. Tan, Nick Li, Lisa C. Heather, Sarah Cooper, Ana Claudia Marques et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Engrailed1 in Parvalbumin‐Positive Neurons Regulates Eye‐Specific Retinogeniculate Segregation and Visual FunctionYuqing Chen, Chengyong Jiang, Biao Yan, Jiayi Zhang · 2024 · Journal of Neuroscience Research
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- Construction of a ceRNA network combining transcription factors in eutopic endometrial tissue of tubal factor infertility and endometriosis-related infertilityJunzui Li, Lulu Ren, Cui Yang, Rongfeng Wu, Zhixiong Huang, Qionghua Chen · 2019
- Nigral Transcriptomic Profiles in Engrailed-1 Hemizygous Mouse Models of Parkinson’s Disease Reveal Upregulation of Oxidative Phosphorylation-Related Genes Associated with Resistance to Dopaminergic NeurodegenerationLautaro F. Belfiori-Carrasco, Alfredo Dueñas Rey, Dorottya Mária Ralbovszki, Itzia Jiménez-Ferrer, Filip Bäckström, Sagar Shivayogi Balikai, Dag Ahrén, Kajsa Atterling Brolin, Maria Swanberg · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Mitochondrial Involvement in Neurodegeneration and AgingAlicia M. Pickrell · 2012
- Funktionelle Analyse des Transkriptionsfaktors Pitx3 während der Entwicklung dopaminerger Neuronen im murinen MittelhirnChristian Krug · 2013
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- Movement disorders 3 Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectivesAnthony H.V. Schapira, C. Warren Olanow, J. Timothy Greenamyre, Erwan Bézard · 2014
- Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factorFederico Miozzo, Luca Stickley, Eva P. Valencia-Alarcón, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Aging and neuronal deathFang Fang, Robert J. Usselman, Renee A. Reijo Pera · 2023 · Aging
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- Long non-coding RNA Cerox1 targets components of the mitochondrial electron transport chain to regulate the memory impairment caused by sleep deprivationKarthick Ravichandran, Pallabi Kisku, Lakhuhong Ningchangmi, Premkumar Palanisamy, Stefan Strack, Ted G. Abel, Sourav Banerjee · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson’s disease modelsEva P. Valencia-Alarcón, Lou C. Duret, Emi Kobayashi, Olivia Cattaneo, Bernard Laurent Schneider, Emi Nagoshi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Embryonic dopaminergic neuron activity sustains lifelong locomotion in DrosophilaAishwarya Padmanabhan, Daniel Rahman, Ruibao Zhu, Salah Khorbtli, Sarugan Sathianathan, Bastien Le Flohic, Lauren Assanga Bisse, Bertrand Mollereau, Cheng Huang, Nikolaos Konstantinides et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Mathematical modeling in neuroscience : collective behavior of neuronal networks & the role of local homeoproteins diffusion in morphogenesisCristóbal Quiñinao · 2015
- Les longs ARN non codants, une nouvelle classe de régulateurs génomique tissu-spécifique : signature moléculaire spécifique des neurones dopaminergiques et sérotoninergiquesJudith Gendron · 2017
- Interaction d’Engrailed avec des partenaires biologiques : FoxA2 et membranes lipidiquesDamien Samson · 2018
- Uncoupling tumorigenicity from dopaminergic differentiation potential of hiPSCs by acting on Glypican4 : combining in vitro differentiation studies with preclinical studies for Parkinson's disease therapySerena Corti · 2019
- Regulation of homeoproteins intercellular transferIrène Amblard · 2020
- Structural characterization of the interaction of homeodomains with PI(4,5)P2-containing membranesEdward Chalouhi · 2022
- Engrailed-1 potentiates mitochondrial transplant neuroprotection in spinal cord ischemia-reperfusion injuryWei Wang, Rui Tang, Shilun Gao, Xiaotian Han, Teng Shi, Tianxiang Gu, Enyi Shi · 2026 · Communications Biology
- Engrailed, a target of the miR-92 family, attenuates Tau accumulation and associated memory deficits in DrosophilaMinh Nguyet Nguyen, Tae Hoon Ryu, Jeong-Soo Lee, Seung-Hyun Hong, Sung-Eun Yoon, Young-Joon Kim, Kweon Yu · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
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- Embryonic dopaminergic neuron activity sustains lifelong locomotion in DrosophilaAishwarya Padmanabhan, Daniel Rahman, Ruibao Zhu, Salah Khorbtli, Sarugan Sathianathan, Bastien Le Flohic, Lauren Assanga Bisse, Bertrand Mollereau, Cheng Huang, Nikolaos Konstantinides et al. · 2026 · Cell Reports
- Engrailed-1 in eccrine sweat gland development and regeneration: from evolutionary innovation to therapeutic perspectivesLei Zhang, Zizhen Zhang, Jiaqi Cheng, Junhong Zhao, Yanyi Xing, Xiang Liu, lihong peng, Sixun Wu, Haihong Li · 2026 · Frontiers in Cell and Developmental Biology