The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit

Shih, Andy Y, Blinder, Pablo, Tsai, Philbert S, Friedman, Beth, Stanley, Geoffrey, Lyden, Patrick D, Kleinfeld, David·2013·Nature Neuroscience

Cited by (352)

Items 301–352 of 352

  1. Observing Cell Behavior in Their Native Environment In Vivo Fluorescence Microscopy: Lessons From
    Sheldon J. J. Kwok, Seok Hyun Yun · 2015
  2. Cerebrovascular Infarct
    Harald W. Sontheimer · 2015 · Elsevier eBooks
  3. Cortical Ischemic Lesion Burden Measured by DIR Is Related to Carotid Artery Disease Severity
    San Raffaele Pisana · 2016
  4. Spatially resolving acute functional changes in descending cortical motor output after targeted stroke
    Eitan Anenberg · 2015 · cIRcle (University of British Columbia)
  5. Investigation of capillary-level blood flow variability through the application of random access multiphoton microscopy to cerebral blood flow imaging
    Daniel J. Christensen, Nedergaard, Maiken, Andrew J. Berger · 2014 · UR Research (University of Rochester)
  6. The Role of Astrocytic Calcineurin Activation and Downstream Signaling in Neurodegenerative Diseases
    Melanie M. Pleiss · 2016 · UKnowledge (University of Kentucky)
  7. Studies of intracortical microelectrode array performance and foreign body response in young and aged rats
    Nicholas F. Nolta · 2018 · J. Willard Marriott Library
  8. Structural Neural Plasticity During Stroke Recovery * *This work was supported by operating, salary, and equipment grants to C.E.B. from CIHR, Heart and Stroke Foundation of BC and Yukon, MSFHR, NSERC, and CFI.
    Kimberly Gerrow, Craig E. Brown · 2017 · Elsevier eBooks
  9. Neurovascular Network as Future Therapeutic Targets
    Yujie Chen, Yang Zhang, Zhen‐Ni Guo, Ling Liu, Feng Gao, Yanfeng Lv, Meng Zhang, Xiaochuan Sun, André Obenaus, Yi Yang et al. · 2018 · Springer series in translational stroke research
  10. Unraveling the heterogeneity of cerebral small vessel disease. From local to remote effects
    Esther M.C. van Leijsen · 2018 · Radboud Repository (Radboud University)
  11. Optical coherence tomography for quantitative analyses of cerebral vessel morphology and hemodynamics
    Wei Wei · 2019 · ResearchWorks at the University of Washington (University of Washington)
  12. Altered 3D Vascular Architecture and Cerebral Blood Flow in a Mouse Model of TBI
    Joe Steinman · 2020 · TSpace (University of Toronto)
  13. Significance of Cortical Micro-Infarcts in the Human Brain
    Jacques L. De Reuck · 2021
  14. Neurophotonics
    Anna Letizia Allegra Mascaro, Ludovico Silvestri, Leonardo Sacconi, Martino Calamai, Francesco Saverio Pavone · 2015 · Wiley eBooks
  15. Cerebrovascular Infarct: Stroke
    Harald W. Sontheimer · 2021 · Elsevier eBooks
  16. Animal Models of Stroke☆
    Lisa C. Hoyte, Brad A. Sutherland, A.M. Buchan · 2016 · Elsevier eBooks
  17. Faculty Opinions recommendation of Microvascular basis for growth of small infarcts following occlusion of single penetrating arterioles in mouse cortex.
    Anne McLaren Dorrance, Paulo Wagner Pires · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  18. Columnar scale lesions in barrel cortex degrade tactile discrimination but not detection
    Lauren Ryan, Maya Laughton, Andrew Sun-Yan, Ravi Pancholi, Simon Peron · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Lipocalin 2 als liquor und plasmabasierter Biomarker bei vaskulärer Enzephalopathie: Assoziationen mit klinischen Merkmalen und verschiedenen Formen der vaskulären Demenz
    Hanna Lindemann · 2023
  20. Brain-wide mapping of layer-specific functional connectivity in the human cortex at 3T using draining-vein-suppressed fMRI
    Wei‐Tang Chang, Weili Lin, Kelly S. Giovanello · 2026 · eLife
  21. Brain-wide mapping of layer-specific functional connectivity in the human cortex at 3T using draining-vein-suppressed fMRI
    Wei‐Tang Chang, Weili Lin, Kelly S. Giovanello · 2023 · eLife
  22. Optogenetic control of arterial diameter in three-dimensions in vivo
    Philip J. O’Herron, David A. Hartmann, Kun Xie, Prakash Kara, Andy Y. Shih · 2024 · Optogenetics and Optical Manipulation
  23. Reviewer #1 (Public Review): Three-photon excited fluorescence microscopy enables imaging of blood flow, neural structure and inflammatory response deep into mouse spinal cord in vivo
    2024 · eLife
  24. Three-photon excited fluorescence microscopy enables imaging of blood flow, neural structure and inflammatory response deep into mouse spinal cord in vivo
    Yu‐Ting Cheng, Kawasi M. Lett, Chris Xu, Chris B. Schaffer · 2024 · eLife
  25. eLife Assessment: Three-photon excited fluorescence microscopy enables imaging of blood flow, neural structure and inflammatory response deep into mouse spinal cord in vivo
    Brice Bathellier · 2024 · eLife
  26. Three-photon excited fluorescence microscopy enables imaging of blood flow, neural structure and inflammatory response deep into mouse spinal cord in vivo
    Yu‐Ting Cheng, Kawasi M. Lett, Chris Xu, Chris B. Schaffer · 2024 · eLife
  27. Reviewer #2 (Public Review): Three-photon excited fluorescence microscopy enables imaging of blood flow, neural structure and inflammatory response deep into mouse spinal cord in vivo
    2024 · eLife
  28. Transient Changes in Cerebral Tissue Oxygen, Glucose, and Temperature by Microstrokes: A Computational Study
    Marzieh Bagheri, Sajjad Habibzadeh, Mohammad Moeini · 2024 · Microcirculation
  29. Enabling brain-wide mapping of directed functional connectivity at 3T via layer-dependent fMRI with draining-vein suppression
    Wei‐Tang Chang, Weili Lin, Kelly S. Giovanello · 2024 · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  30. Computational modeling of immersed non-spherical bodies in viscous flows to study embolus-hemodynamics interactions in large-vessel occlusion stroke
    Chayut Teeraratkul, Adarsh Krishnamurthy, Debanjan Mukherjee · 2026 · Engineering With Computers
  31. Enabling brain-wide mapping of layer-specific functional connectivity at 3T via layer-dependent fMRI with draining-vein suppression
    Wei‐Tang Chang, Weili Lin, Kelly S. Giovanello · 2025 · eLife
  32. Brain & Brain pet 2025 Abstracts
    Serena Seminara, A Bianchi, Davide Comolli, M Spreafico, Alessandro Fantin, Massimiliano De Paola, S. Fumagalli · 2025 · Journal of Cerebral Blood Flow & Metabolism
  33. Relationship between first pass effect NLR and PLR in mechanical thrombectomy for acute anterior circulation large-vessel occlusion
    Guozhang Lu, Peijian Wang, Bin Xv, Hang Lv, Liyong Zhang, Jiyue Wang, Jiheng Hao · 2025 · Frontiers in Neurology
  34. Sometimes Smaller Is Better
    William F. Jackson · 2025 · Circulation Research
  35. Cerebral Microbleeds with a Venous Connection on 3 Tesla Susceptibility-Weighted Imaging in Persons with Alzheimer’s Disease and Healthy Aging Controls
    Ulf Jensen‐Kondering, Veronique Kuhn, Hannes Schacht, Alexander Neumann, Georg Royl, Peter Schramm · 2025 · Brain Sciences
  36. Blood Flow Simulation and Uncertainty Quantification in Extensive Microvascular Networks: Application to Brain Cortical Networks
    Peter Mondrup Rasmussen · 2025 · Microcirculation
  37. Differential effects of aging and Alzheimer’s disease on microemboli clearance in a mouse model of microinfarction
    Fiona O. Haugen, G. Silasi · 2025 · bioRxiv
  38. Simultaneous Photothrombosis and Fiber Photometry to Induce and Monitor Ischemic Stroke in Behaving Mice
    Briana Montoya, Roger J. Thompson, Andrew K. J. Boyce · 2025 · Journal of Visualized Experiments
  39. Additional file 4 of Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain
    Anne‐Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, Bert J. van het Hof, Helga E. de Vries, Stephan Huveneers, Peter Lodewijk Hordijk, Erik N.T.P. Bakker et al. · 2020 · Figshare
  40. Additional file 1 of Increased serum QUIN/KYNA is a reliable biomarker of post-stroke cognitive decline
    Adrien Cogo, Gabrielle Mangin, Benjamin Maïer, Jacques Callebert, Mikaël Mazighi, Hugues Chabriat, Jean‐Marie Launay, Gilles Huberfeld, Nathalie Kubis · 2021 · Figshare
  41. Additional file 1 of Overexpression of Slit2 decreases neuronal excitotoxicity, accelerates glymphatic clearance, and improves cognition in a multiple microinfarcts model
    He, Xiao-fei, Li, Ge, Li, Li-li, Li, Ming-yue, Liang, Feng-yin, Chen, Xi, Xiquan Hu · 2020 · Figshare
  42. Additional file 2 of Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain
    Anne‐Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, Bert J. van het Hof, Helga E. de Vries, Stephan Huveneers, Peter Lodewijk Hordijk, Erik N.T.P. Bakker et al. · 2020 · Figshare
  43. Additional file 1 of Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain
    Anne‐Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, van het Hof, Bert J., Helga E. de Vries, Stephan Huveneers, Peter Lodewijk Hordijk, Erik N.T.P. Bakker et al. · 2020 · Figshare
  44. Additional file 9 of Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain
    Anne‐Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, Bert J. van het Hof, Helga E. de Vries, Stephan Huveneers, Peter Lodewijk Hordijk, Erik N.T.P. Bakker et al. · 2020 · Figshare
  45. A Pathophysiological Model of Parkinson’s Disease Based on Microvascular Flow Disturbance and Leukocyte-Mediated Oxidative Injury in Critical Pigmented Neuronal Niches
    Emilio Fernández‐Espejo, Fernando Rodrı́guez de Fonseca · 2026 · Antioxidants
  46. Microvascular network organization and hemodynamic perfusion protect the brain against hypoxia
    Thomas Ventimiglia, Frédéric Lesage, Andreas A. Linninger · 2026 · Journal of Cerebral Blood Flow & Metabolism
  47. Chemogenetic Pericyte Activation Reveals Broad Contractile Ability and Limbic Vulnerability to Capillary Flow Deficits
    Liam T. Sullivan, Dickson T. Chen, Catherine Foster, Ben Zimmerman, Kevin J Elk, Bradley D. Marxmiller, Taylor McGillis, Yuandong Li, Stephanie K. Bonney, Lila D. Faulhaber et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  48. Exploring the Research Progress of Vascular Dementia and Key Regulatory Molecules: E2F1
    Fengwei Zhang, Zhihua Hao, Mingrong Song, Zihan Zhao, Wanying Li, Jing Chen · 2026 · International Journal of Molecular Sciences
  49. Ischemic stroke: molecular mechanisms of blood-brain barrier dysfunction and opportunities for drug development
    Patrick T. Ronaldson, Thomas P. Davis · 2026 · Fluids and Barriers of the CNS
  50. A reproducible rat model of microembolic brain injury using percutaneous coaxial microcatheter delivery of zirconia beads
    Kentaro Kasa, Hiroki Ohta, Teppei Komatsu, Misato Yoshioka, Dai Kejia, Makoto Koizumi, Takao Ohki, Hirotaka James Okano · 2026 · Journal of Neuroscience Methods
  51. Accelerated and memory-efficient clutter filtering toward online-compatible ultrasound localization microscopy via compressed-matrix randomized QRD
    Youngho Seo, Myeongchan Kim, Nizar Guezzi, Hyojin Seong, Seonghyeon Cho, Jinhwan Jung, Sangwoo Nam, Dongkyu Jung, Eungyeong Cho, Jung Ho Hyun et al. · 2026 · Ultrasonics
  52. TRP channels in cerebral vascular disorders
    Giovanna Paone, Josiane F. Silva, Paulo Wagner Pires · 2026 · Frontiers in Biophysics