Tau promotes neurodegeneration through global chromatin relaxation

Frost, Bess, Hemberg, Martin, Lewis, Jada, Feany, Mel B·2014·Nature Neuroscience

DOI 10.1038/nn.3639

Cited by (486)

Items 401–486 of 486

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INVESTIGATION INTO THE FUNCTIONAL ROLES OF TAU AND ALPHA-SYNUCLEIN IN NEURODEGENERATIVE DISEASE
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Hyung Don Ryoo · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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Targeted down-regulation of Hipp1 ameliorates tau-induced deficits in Drosophila melanogaster
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Tau Protein Modulates an Epigenetic Mechanism of Cellular Senescence
Claudia Magrin, Martina Sola, Ester Piovesana, Marco Bolis, Andrea Rinaldi, Stéphanie Papin, Paolo Paganetti · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Cancer-specific association between Tau ( MAPT ) and cellular pathways, clinical outcome, and drug response
Maurizio Callari, Martina Sola, Claudia Magrin, Andrea Rinaldi, Marco Bolis, Paolo Paganetti, Luca Colnaghi, Stéphanie Papin · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Nuclear translocation of LINE-1 encoded ORF1p alters nuclear envelope integrity and disrupts nucleocytoplasmic transport in human neurons
Rania Znaidi, Olivia Massiani-Beaudoin, Philippe Mailly, Héloïse Monnet, The Brainbank Neuro-CEB Neuropathology Network, Rajiv L. Joshi, Julia Fuchs · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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Human endogenous retroviruses are upregulated in Frontotemporal Dementia-MAPT mutation carriers
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Additional file 4 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
Maria Bichmann, Nuria Prat Oriol, Ebru Ercan-Herbst, David C. Schöndorf, Borja Gomez Ramos, Vera Schwärzler, Neu, Marie, Annabelle Schlüter, Xue Wang, Liang Jin et al. · 2021 · Figshare
Additional file 1 of Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
Pieter Jelle Visser, Lianne Maria Reus, Johan Gobom, Iris E. Jansen, Ellen Dicks, Sven J. van der Lee, Magda Tsolaki, Frans R.J. Verhey, Julius Popp, Pablo Martínez‐Lage et al. · 2022 · Figshare
Additional file 2 of Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease
Dongmei Chen, Guihua Lan, Ruomeng Li, Yingxue Mei, Xindong Shui, Gu, Xi, Long Wang, Zhang, Tao, Chen‐Ling Gan, Yongfang Xia et al. · 2022 · Figshare
Two major culprits: Amyloidogenic Aβ and non-amyloidogenic tau
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A new screening assay reveals that aminoglycoside antibiotics interfere with the Tau/MDM2 interaction
Martina Sola, Matteo Ciccaldo, Paolo Paganetti, Stéphanie Papin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Antiatherosclerotic effects of postbiotics
A. Vijayaganapathi, Anju K.A., Shree Kumari G R, C. Subathra Devi, Mohanasrinivasan Vaithilingam · 2025 · Elsevier eBooks
Urban Air Pollution Exposure Impairs Memory and Social Behavior and Reduces the Repressive Epigenetic Marks H3k9me2/3 in the Mouse Hippocampus and Olfactory Bulb
Nur Jury, Mario Sánchez-Rubio, Gino Nardocci, Constanza Mercado, Nicolas Peña-Baeza, Pablo Ruiz-Rudolph, Martin A. Montecino, Lorena Varela‐Nallar, Brigitte van Zundert · 2025 · SSRN Electronic Journal
Tau deficiency contributes to impaired bone formation via activating PPARγ signaling
Meipeng Zhu, Shunze Hu, Jian Liu, Hui Chun Huang, Xuying Sun · 2025 · Cellular Signalling
Aere perennius: how chromatin fidelity is maintained and lost in disease
Dustin R Fetch, Amina Jumamyradova, Cameron M Chapa, Yong Ge, Mansour Mohamadzadeh, Alexey A. Soshnev · 2025 · NAR Molecular Medicine
Microcephaly-Associated Genes asp and Sas4 Control Chromatin Organization and Nuclear Lamina Structure in Drosophila melanogaster
Degisew Yinur Mengistu, Marta Marzullo, Claudia Pellacani, Marcella Marchetti, Marta Terribili, Emma Montivero Morales, Maria Patrizia Somma, Laura Ciapponi · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Urban air pollution reduces H3K9me2/me3 in hippocampal and olfactory neurons, correlating with memory and social deficits
Nur Jury, Mario Sánchez-Rubio, Gino Nardocci, Constanza Mercado, Nicolas Peña-Baeza, Pablo Ruiz-Rudolph, Martin A. Montecino, Lorena Varela‐Nallar, Brigitte van Zundert · 2025 · The Science of The Total Environment
Role of Nuclear Lamins in the Regulation of the Genome: Focus on CardioLaminopathy
Marie Kervella, Antoine Muchir · 2025 · Sub-cellular biochemistry/Subcellular biochemistry
A proteomic analysis of the PHF-forming tau fragment (tau297–391) following uptake into differentiated human neuronal SHSY5Y cells
Alice C. Copsey, Sebastian Scott Oakley, Mahmoud Bukar Maina, Robert Parker, Karen E. Marshall, Charles R. Harrington, John M.D. Storey, Claude M. Wischik, Louise C. Serpell · 2026 · Bioscience Reports
Transposable Elements as Drivers of Age-Related Neurodegenerative Disease
Chiara Scopa, Megan Muench, Davide Trotti · 2025 · Epigenetics and human health
Retrotransposons as both “architects” and “saboteurs” in the nervous system
Nuria Izquierdo‐Useros, Mara Dierssen, Bonaventura Clotet, Aleix Elizalde‐Torrent, Paulina Carriba · 2025 · Advances in genetics
Retrotransposon Activation in the Aged and Alzheimer’s Disease Brain Examined by Nanopore Long-read DNA Sequencing
Maxfield M. G. Kelsey, Anjalika Chongtham, John LaCava, Martin S. Taylor, Jef D. Boeke, Fred H. Gage, Andrei Seluanov, Vera A. Gorbunova, Ana C. Pereira, John M. Sedivy · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Additional file 1 of Clusters of co-abundant proteins in the brain cortex associated with fronto-temporal lobar degeneration
Claire Bridel, Juami H. M. van Gils, Suzanne S. M. Miedema, Jeroen J.M. Hoozemans, Yolande A.L. Pijnenburg, August B. SMIT, Annemieke J.M. Rozemüller, Sanne Abeln, Charlotte Elisabeth Teunissen · 2024 · Figshare
Additional file 2 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
Maria Bichmann, Prat Oriol, Nuria, Ebru Ercan-Herbst, David C. Schöndorf, Gomez Ramos, Borja, Vera Schwärzler, Marie Astrid Neu, Annabelle Schlüter, Wang, Xue, Liang Jin et al. · 2021 · Figshare
Additional file 1 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
Additional file 3 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
Maria Bichmann, Prat Oriol, Nuria, Ebru Ercan-Herbst, David C. Schöndorf, Gomez Ramos, Borja, Vera Schwärzler, Marie Astrid Neu, Annabelle Schlüter, Wang, Xue, Jin, Liang et al. · 2021 · Figshare
Additional file 1 of Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease
Chen, Dongmei, Guihua Lan, Ruomeng Li, Yingxue Mei, Xindong Shui, Gu, Xi, Wang, Long, Zhang, Tao, Gan, Chen-Ling, Yongfang Xia et al. · 2022 · Figshare
Additional file 2 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
Additional file 4 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil N. Bhatt, Rakez Kayed · 2020 · Figshare
Additional file 3 of P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease
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Additional file 1 of SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
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Additional file 2 of Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
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