Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

De Jager, Philip L, Srivastava, Gyan, Lunnon, Katie, Burgess, Jeremy, Schalkwyk, Leonard C, Yu, Lei, Eaton, Matthew L, Keenan, Brendan T +21 more·2014·Nature Neuroscience

DOI 10.1038/nn.3786

Cited by (976)

Items 601–700 of 976

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Basavaraj V. Hooli, Rudolph E. Tanzi · 2016 · Elsevier eBooks
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Eilis J. Hannon, Annisa N. Chand, Mark D. Evans, Chloe C. Y. Wong, Matthew S. Grubb, Jonathan S. Mill · 2015 · Neuroepigenetics
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Heather B. Wood · 2014 · Nature Reviews Neurology
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