Genetic variability in the regulation of gene expression in ten regions of the human brain

UK Brain Expression Consortium, Ramasamy, Adaikalavan, North American Brain Expression Consortium, Trabzuni, Daniah, Guelfi, Sebastian, Varghese, Vibin, Smith, Colin, Walker, Robert +8 more·2014·Nature Neuroscience

DOI 10.1038/nn.3801

Cited by (651)

Items 501–600 of 651

Ethnicity-dependent effects of Zinc finger 804A variant on schizophrenia: a systematic review and meta-analysis
Dandan Wang, Yewei Wang, Yan Chen, Lingfang Yu, Xinyu Fang, Ruimei Liu, Zenan Wu, Chen Zhang · 2020 · Psychiatric Genetics
Modeling multifunctionality of genes with secondary gene co-expression networks in human brain provides novel disease insights
Juan A Sánchez, Ana Luisa Gil-Martínez, Alejandro Cisterna‐García, Sonia García-Ruiz, Alicia Gómez-Pascual, Regina Hertfelder Reynolds, Mike A. Nalls, John Hardy, Mina Ryten, Juan Antonio Botía · 2021 · Bioinformatics
Evaluation of Genotype-Based Gene Expression Model Performance: A Cross-Framework and Cross-Dataset Study
Vânia Tavares, Joana Monteiro, Evangelos Vassos, Jonathan R. I. Coleman, Diana Pinto Prata · 2021 · Genes
Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability
Guillaume Huguet, Catherine Schramm, Elise A. Douard, Petra Tamer, Antoine Main, Pauline Monin, Jade England, Khadijé Jizi, Thomas Renne, Myriam Poirier et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Variant-risk-exon interplay impacts circadian rhythm and dopamine signaling pathway in severe psychiatric disorders
Karolina Worf, Natalie Matosin, Nathalie Gerstner, Anna Sophie Fröhlich, Anna C. Koller, Franziska Degenhardt, Hölger Thiele, Marcella Rietschel, Madhara Udawela, Elizabeth Scarr et al. · 2022 · medRxiv
Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry
Megan Skelton, Brittany L. Mitchell, Elham Assary, Danyang Li, Geneviève Morneau‐Vaillancourt, Alan E Murphy, Abigail ter Kuile, Rujia Wang, Mark J. Adams, Enda M. Byrne et al. · 2026 · Nature Human Behaviour
A systems biology-based identification and in vivo functional screening of Alzheimer’s disease risk genes reveal modulators of memory function
Adam D. Hudgins, Shiyi Zhou, Rachel N. Arey, Michael G. Rosenfeld, Coleen T. Murphy, Yousin Suh · 2024 · Neuron
A Genome-Wide Association Study of First-Episode Psychosis: A Genetic Exploration in an Italian Cohort
Mirko Treccani, Lucia Maggioni, Claudia Di Giovanni, Laura Veschetti, Doriana Cristofalo, Cristina Patuzzo, Antonio Lasalvia, Branko Ristic, Roushan Kumar, The PICOS-Veneto Group et al. · 2025 · Genes
Differential Network Analysis and Graph Classification: A Glocal Approach
Giuseppe Jurman, Michele Filosi, Samantha Riccadonna, Roberto Visintainer, Cesare Furlanello · 2016 · Springer eBooks
Bioinformatics in the Identification of Novel Targets and Pathways in Neurodegenerative Diseases
Jussi Paananen · 2017 · Current Genetic Medicine Reports
Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population
Fan Wang, Shunying Yu, Rubai Zhou, Ruizhi Mao, Guoqing Zhao, Xiaoyun Guo, Qingqing Xu, Jun Chen, Chen Zhang, Yiru Fang · 2020 · Neuropsychiatric Disease and Treatment
A pH-eQTL Interaction at the RIT2–SYT4 Parkinson’s Disease Risk Locus in the Substantia Nigra
Sejal Patel, Derek Howard, Leon French · 2021 · Frontiers in Aging Neuroscience
Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional validation across brain
Xingguang Luο, Xiandong Lin, Jaime S. Ide, Xinqun Luo, Yong Zhang, Jianying Xu, Leilei Wang, Yu Shan Chen, Wenhong Cheng, Jianming Zheng et al. · 2023 · Child and Adolescent Psychiatry and Mental Health
Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations
Sandro Marini, Jaeyoon Chung, Xudong Han, Xinyu Sun, Livia Parodi, Lindsay A. Farrer, Jonathan M. Rosand, Jose Rafael Romero, Christopher D. Anderson · 2023 · International Journal of Stroke
A significant, functional and replicable risk KTN1 variant block for schizophrenia
Qiao Mao, Xiandong Lin, Qin Yin, Ping Liu, Yong Zhang, Shihao Qu, Jianying Xu, Wenhong Cheng, Xinqun Luo, Longli Kang et al. · 2023 · Scientific Reports
Identification of an novel genetic variant associated with osteoporosis: insights from the Taiwan Biobank Study
Yi‐Ching Liaw, Koichi Matsuda, Yung‐Po Liaw · 2024 · JBMR Plus
The Role of 3’ Regulatory Region Flanking Kinectin 1 Gene in Schizophrenia
Xiaoyun Guo, Xinqun Luo, Xiaoyi Huang, Yong Zhang, Jiawu Ji, Xiaoping Wang, Kesheng Wang, Jijun Wang, Xinghua Pan, Bin Chen et al. · 2024 · ALPHA PSYCHIATRY
Genetic Markers of Postmortem Brain Iron
Marilyn C. Cornelis, Amir Fazlollahi, David A. Bennett, Julie A. Schneider, Scott Ayton · 2025 · Journal of Neurochemistry
A PheWAS approach to identify associations of GBA1 variants with comprehensive phenotypes beyond neurological diseases
Jiaqi Yang, Yuanfeng Huang, Zheng Wang, Shiyu Zhang, Dai Wu, Jiayi Xiong, Heng Wu, Yijing Wang, Qiao Zhou, Yixiao Zhu et al. · 2025 · npj Parkinson s Disease
Enhanced plasma and brain concentrations and medulloblastoma cytotoxicity of asciminib and nilotinib by P-glycoprotein inhibition with tariquidar
Eric M. Thompson, Lin Cheng, Ivan Spasojević · 2025 · Anti-Cancer Drugs
Dyslexia risk variant rs600753 is linked with dyslexia-specific differential allelic expression of DYX1C1
Bent Müller, Johannes Boltze, Ivonne Czepezauer, V. Hesse, Arndt Wilcke, Holger Kirsten · 2018 · Genetics and Molecular Biology
Mining Regional Imaging Genetic Associations via Voxel-wise Enrichment Analysis
Xiaohui Yao, Shan Cong, Jingwen Yan, Shannon L. Risacher, Andrew J. Saykin, Jason H. Moore, Li Shen · 2019 · IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI ...)
RETRACTED: Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer’s Disease
Jessie S. Carr, Luke W. Bonham, Alicia Katherine Morgans, Charles J. Ryan, Jennifer S. Yokoyama, Ethan G. Geier, Alzheimer’s Disease Neuroimaging Initiative · 2018 · Frontiers in Neuroscience · Retracted
Association Between ZNF804A Gene rs1344706 Polymorphism and Brain Functions in Healthy Individuals: A Systematic Review and Voxel-Based Meta-Analysis
Liqiong Yang, Fan Xu, Yi He, Yanzhang Li, Zi Chen, Shuai Wang · 2021 · Neuropsychiatric Disease and Treatment
Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease
Viola Volpato · 2021 · Biochemical Society Transactions
Pharmacogenomics and antipsychotics: efficacy and adverse drug reactions
Evangelia Eirini Tsermpini, Tea Terzi, Blanka Kores Plesničar, Vita Dolžan · 2022 · Elsevier eBooks
Family-based association study of ZNF804A polymorphisms and autism in a Han Chinese population
Ziqi Wang, Tian Zhang, Jing Liu, Han Wang, Tianlan Lu, Meixiang Jia, Dai Zhang, Lifang Wang, Jun Li · 2019 · BMC Psychiatry
Online Supplemental Material
Diana Steger, Ulrich Schroeders, Oliver Wilhelm · 2018
Association of the GRIK4 rs1954787 polymorphism with clinical response in antidepressant-treated depressed patients: results from a prospective cohort and meta-analysis
Kenneth Chappell, Romain Colle, Khalil El Asmar, Florence Gressier, Jérôme Bouligand, Séverine Trabado, Bruno Fève, Laurent Becquemont, Emmanuelle Corruble, Céline Verstuyft · 2024 · Molecular Psychiatry
Allelic frequency differences of DAOA variants between Caucasians and Asians and their association with major mood disorders
Zhi-hua Yang, Shuang Zhang, Fuquan Zhang, Yao Yao, Kwang-Woo Kim, David Meyre, Hongmei Zhang, Hai Liao, Shuquan Rao, Xinhe Huang · 2019 · Signal Transduction and Targeted Therapy
A combined proteomics and bioinformatics analysis of ZNHIT1-interacting proteins reveals a significant enrichment in proteins associated with mitochondrial function
Jayanth Anantha, Fionnuala Wilson, Erin McCarthy, Noelia Morales‐Prieto, Martina Mazzocchi, Louise Collins, Aideen M. Sullivan, Gerard W. O’Keeffe · 2023 · Journal of Chemical Neuroanatomy
Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally
Karishma D’Sa, Sebastian Guelfi, Jana Vandrovcová, Regina Hertfelder Reynolds, David Zhang, John Hardy, Juan Antonio Botía, Michael E. Weale, Sarah A. Gagliano Taliun, Kerrin S. Small et al. · 2023 · Scientific Reports
Deep Trans-Omic Network Fusion for Molecular Mechanism of Alzheimer’s Disease
Xie, Linhui, Raj, Yash, Varathan, Pradeep, He, Bing, Yu, Meichen, Nho, Kwangsik, Salama, Paul, Saykin, Andrew J., Yan, Jingwen · 2024 · Journal of Alzheimer's Disease
Associations between antagonistic SNPs for neuropsychiatric disorders and human brain structure
Lydia M Federmann, Friederike Sophie David, Christiane Jockwitz, Thomas W. Mühleisen, Dominique I. Pelzer, Markus Maria Nöthen, Svenja Caspers, Katrin Amunts, Janik Goltermann, Till F. M. Andlauer et al. · 2024 · Translational Psychiatry
Local cortical structure pattern and genetic links in schizophrenia: An MRI and CRISPR/Cas9 study
Pei-Shan Hou, Shu-fei Lin, Jun‐Ding Zhu, Chih-Yun Chung, Shih‐Jen Tsai, Albert C. Yang · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
Sex‐stratified genome‐wide meta‐analysis identifies novel loci for cognitive decline in older adults
Vibha Acharya, Kang-Hsien Fan, Beth Ellen Snitz, Mary Ganguli, Steven Trent DeKosky, Oscar L. López, Eleanor Feingold, M. Ilyas Kamboh · 2025 · Alzheimer s & Dementia
Motor learning is regulated by postnatal GDNF levels in Purkinje cells
Elina I. Nagaeva, Giorgio Turconi, Kärt Mätlik, Mikael Segerstråle, Soophie Olfat, Vilma Iivanainen, Tomi Taira, Jaan‐Olle Andressoo · 2025 · Neuroscience
Brain-derived Neurotrophic Factors Val66Met and C270T Polymorphisms Influence Citalopram/Escitalopram Response in Chinese Patients with Major Depressive Disorder
D Zeng, Shuchang He, J. Y. Li, R. Zhang, D. X Wang, H. F. Li, Yifeng Shen · 2019 · Indian Journal of Pharmaceutical Sciences
Comprehensive analysis of shared genetic loci between hippocampal volume and schizophrenia
Zongchang Li, Xiaogang Chen · 2022 · Psychiatry Research
Bayesian mixed model inference for genetic association under related samples with brain network phenotype
Xinyuan Tian, Yiting Wang, Selena Wang, Yi Zhao, Yize Zhao · 2024 · Biostatistics
Integrated Systems Approach Reveals Sphingolipid Metabolism Pathway Dysregulation in Association with Late-Onset Alzheimer’s Disease
John Stephen Malamon, Andres Kriete · 2018 · Biology
Comprehensive Analysis of Alzheimer’s Disease Biologically Candidate Causal Genes Revealed by Function Association Study With GWAS
Yannan Bin, Qizhi Zhu, Menglu Li, Junfeng Xia · 2019 · IEEE Access
Identification of Brain Expression Quantitative Trait Loci Associated with Schizophrenia and Affective Disorders in Normal Brain Tissue
Oneil G. Bhalala, Artika P. Nath, Michael Inouye, Christopher R. Sibley · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
GWAS meta-analysis highlights the hypothalamic-pituitary-gonadal axis (HPG axis) in the genetic regulation of menstrual cycle length
Triin Laisk, Viktorija Kukuškina, Duncan S. Palmer, Samantha Laber, Chia‐Yen Chen, Teresa Cruz Ferreira, Nilüfer Rahmioğlu, Krina T. Zondervan, Christian Malte Becker, Jordan W. Smoller et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Lipid associated polygenic enrichment in Alzheimer’s disease
Iris Broce, Chin Hong Tan, Chun Chieh Fan, Aree Witoelar, Natalie Wen, Iris E. Jansen, Christopher Paul Hess, William P. Dillon, Christine M. Glastonbury, M. Maria Glymour et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders
Εvangelos Εvangelou, He Gao, Congying Chu, Georgios Ntritsos, Paul Blakeley, Andrew R. Butts, Raha Pazoki, Hideaki Suzuki, Fotios Koskeridis, Andrianos M. Yiorkas et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Sparse parallel independent component analysis and its application to identify linked genomic and gray matter alterations underlying working memory impairment in attention-deficit/hyperactivity disorder
Kuaikuai Duan, Jiayu Chen, Vince D. Calhoun, Wenhao Jiang, Kelly Rootes-Murdy, Gido Schoenmacker, Rogers F. Silva, Barbara Franke, Jan K. Buitelaar, Martine Hoogman et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Finding drug targeting mechanisms with genetic evidence for Parkinson’s disease
Catherine S. Storm, Demis A. Kia, Mona Mohammad Almramhi, Sara Bandrés‐Ciga, Chris Finan, Aroon Dinesh Hingorani, Nicholas William Wood · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Cell group analysis reveals changes in upper-layer neurons associated with schizophrenia
Rujia Dai, Lulu Chen, Sihan Liu, Chiung-Ting Wu, Yu Chen, Yi Wei Jiang, Rujia Dai, Qihang Wang, Richard F. Kopp, Guoqiang Yu et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Uncovering the multivariate genetic architecture of frailty with genomic structural equation modelling
Isabelle Francesca Foote, Jonny P Flint, Anna Elisabeth Fürtjes, Donncha S. Mullin, John D. Fisk, Tobias K. Karakach, Andrew D. Rutenberg, Nicholas G. Martin, Michelle K. Lupton, David J. Llewellyn et al. · 2024 · medRxiv
Multivariate, Multi-omic Analysis in 799,429 Individuals Identifies 134 Loci Associated with Somatoform Traits
Christal N. Davis, Sylvanus Toikumo, Alexander Samir Hatoum, Yousef Khan, Benjamin K. Pham, Shreya Reddy Pakala, Kyra L. Feuer, Joel E. Gelernter, Sandra Sanchez‐Roige, Rachel L. Kember et al. · 2024 · medRxiv
Trailblazing Contemporary Frameworks for Drug Repurposing: A Saga on Drugs’ Expedition to Disinter the Veiled Destiny
Kshreeraja S. Satish, Ganesan Rajalekshmi Saraswathy, G. N. S. Hemasree, Kamatchi Sundara Saravanan, V. Lakshmi Prasanna Marise, Mamatha Krishna Murthy, Manikanta Murahari · 2023 · Springer eBooks
Identification of potential crucial genes and therapeutic targets for epilepsy
Shitao Wang, Zhenrong Xie, Jun Tian, Xuelu Ma, Mengen Zhang, Feng Rao, Hui Xu, Jinghong Lu, Xiangqian Ding, Zongyou Li · 2024 · European journal of medical research
Exploring the Genetic Underpinnings of Diffusion Tensor Image Analysis Along the Perivascular Space: A Genome-Wide Correlation Study and Implications for Brain Health
Jiancheng Wu, Diaohan Xiong, Xinyu Wang, Ruihua Zhu, Nana Liu, Zirui Wang, Xingyu Zhang, Meng Cheng, Zhixuan Liu, Siqi Wang et al. · 2025 · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
Unveiling the clinical and genetic impact of neuropsychiatric involvement in systemic lupus erythematosus
Soojin Cha, Ga Young Ahn, Kwang-Woo Kim, Hye‐Soon Lee, Sang-Cheol Bae, So‐Young Bang · 2025 · RMD Open
Associations of air pollution and genetic risk and their interaction with risk of Alzheimer’s disease: identification of risk loci and potential biological pathways
Shanshan Ran, Jingyi Zhang, Miao Cai, Lie Chen, Zhengmin Min Qian, Fei Tian, Gan Wu, Ri’enna Boyd, Stephen Edward McMillin, Huai-cai Zeng et al. · 2026 · GeroScience
Dysregulated Notch1 signaling in seizures: Insights from a genetic model of absence epilepsy
Ali Gorji, Noormohammad Meshkinkhood, Hasan Hosseini Ravandi, Sayed Mostafa Modarres Mousavi, Fatemeh Alipour, Arezou Eshaghabadi, Farshid Nourbakhsh · 2026 · Epilepsy Research
A prototype-augmented graph representation learning framework for identifying brain disorder-associated genes and facilitating drug repurposing
Jiafang Li, Yifei Li, Siying Lin, Jiahua Rao, Huiying Zhao · 2026 · PLoS Computational Biology
Co-expression-based models improve eQTL predictions for transcriptome-wide association studies and highlight new schizophrenia-associated genes
Fabiana Rossi, Leonardo Sportelli, Gianluca Christos Kikidis, Giulia Grassi, Fabio Di Camillo, Alessandro Bertolino, Giuseppe Blasi, Christopher Borcuk, Daniela Fusco, Thomas M. Hyde et al. · 2026 · Nature Genetics
Further Evidence for Role of Promoter Polymorphisms in TNF Gene in Alzheimer’s Disease
Yannan Bin, Ling Shu, Qizhi Zhu, Huanhuan Zhu, Junfeng Xia · 2018 · Lecture notes in computer science
Death Characteristics of Neurological Diseases in Inner Mongolia between 2008 and 2015
Yujia Ma, Yonggang Qian, Zhiqiang Sun, Mingzhu Niu, Du Yu, Hongwei Li, Ruijie Wu, Ying Yang, Hairong Zhang, Xiaoling X. Sun et al. · 2019 · Open Journal of Preventive Medicine
Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a trans-eQTL Associated with MPZ Gene in Substantia Nigra.
Letitia M.F. Sng, Peter Campbell Thomson, Daniah Trabzuni · 2020 · PubMed
Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability
Xinyu Guo, Nilanjan Chatterjee, Diptavo Dutta · 2024 · Human Genetics and Genomics Advances
Unveiling the role of phytochemicals in autism spectrum disorder by employing network pharmacology and molecular dynamics simulation
Anurag Thapliyal, Kapali Suri, Rudrakshi Chauhan, N. Arul Murugan, Shashank Kumar Maurya · 2024 · Metabolic Brain Disease
Genome-wide association studies
Thomas W. Mühleisen, Sven Cichon · 2019
Population neuroscience in addiction research
Tomáš Paus · 2019 · Elsevier eBooks
Estimating the effects of copy‐number variants on intelligence using hierarchical Bayesian models
Lai Jiang, Guillaume Huguet, Catherine Schramm, Antonio Ciampi, Antoine Main, Claudine Passo, Martineau Jean‐Louis, Maude Auger, Günter Schumann, David John Porteous et al. · 2020 · Genetic Epidemiology
Association of the soluble CTLA4 with schizophrenia: an observational study
Lei Cai, Xuhan Yang, Yani Kang, Wen Wen, Fuquan Zhang, Weihua Yue, Qian Zhang, Fangyu Chen, Wen Cao, Jun Yue et al. · 2020 · Journal of Bio-X Research
MEF2C gene variations are associated with ADHD in the Chinese Han population: a case–control study
Xihang Fu, Ting Yao, Xinzhen Chen, Huiru Li, Jing Wu · 2022 · Journal of Neural Transmission
Interaction analysis between germline genetic variants and somatic mutations in head and neck cancer
Guanying Feng, Hongjie Feng, Yibo Qi, Tianxiao Wang, Nan Ni, Jia Wu, Hua Yuan · 2022 · Oral Oncology
Genomics implicates adaptive and innate immunity in Alzheimer’s and Parkinson’s
Sarah A. Gagliano Taliun, Jennie G. Pouget, John Hardy, Jo Knight, Michael R. Barnes, Mina Ryten, Michael E. Weale · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
[History of surgery in Preci better known as surgeons of Norcia].
F Guiggi, Giammario Giustozzi · 1999 · PubMed
CXCR4 involvement in neurodegenerative diseases
Luke W. Bonham, Celeste M M. Karch, Chun Chieh Fan, Chin Hong Tan, Ethan G. Geier, Yunpeng Wang, Natalie Wen, Iris Broce, Yi Li, Matthew J. Barkovich et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
CoExp Web, a web tool for the exploitation of co-expression networks
Sonia García-Ruiz, Ana Luisa Gil-Martínez, Alejandro Cisterna‐García, Federico Jurado-Ruiz, Regina Hertfelder Reynolds, Mark R. Cookson, John Hardy, Mina Ryten, Juan Antonio Botía · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
Characteristics of jaundice and cholestasis in a Finnish population.
P. Pasanen, Kaarina P. L. Partanen, P. H. Pikkarainen, E. M. ALHAVA · 1992 · PubMed
Specificity of cortical area and thickness as biomarkers for comorbid internalizing and externalizing mental disorders in pre-adolescence
Nanyu Kuang, Zhaowen Liu, Gechang Yu, Kai Zhang, Xinran Wu, Benjamin Becker, Huaxin Fan, Jiajia Zhao, Jujiao Kang, Guiying Dong et al. · 2022 · medRxiv
IL-6R Protective Variant rs7529229 Reduces Interleukin-6 Signaling and Contributes To A Decreased Ischemic Stroke Risk
Haihua Zhang, Wen-Bo Zhao, Bian Liu, Tao Wang, Zhi-Fa Han, Xun-Ming Ji, Guiyou Liu · 2020
Inflammatory Bowel Disease and Neurodegenerative Disorders: Integrated Evidence from Mendelian Randomization, Shared Genetic Architecture and Transcriptomics
Ruijie Zeng, Jinghua Wang, Rui Jiang, Jie Yang, Chunwen Zheng, Huihuan Wu, Zewei Zhuo, Qi Yang, Jingwei Li, Felix W. Leung et al. · 2022 · medRxiv
Genome-wide association study of ACE inhibitor-induced cough implicates neuropeptides and shows genetic overlap with chronic dry cough
Kayesha Coley, David J. Shepherd, Richard J. Packer, Catherine John, Robert C. Free, Edward J. Hollox, Louise V. Wain, Martin D. Tobin, Chiara Batini · 2022 · medRxiv
Expression based polygenic scores - A gene network perspective to capture individual differences in biological processes
Bárbara Barth, Euclides José de Mendonça Filho, Danusa Mar Arcego, Irina Pokhvisneva, Michael Joseph Meaney, Patrícia Pelufo Silveira · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Defining The Potential Of Gene Therapy With Bone Morphogenetic Proteins As A Novel Therapeutic Approach In Parkinson's Disease
Susan R. Goulding · 2021
Multivariate, Multi-omic Analysis in 799,429 Individuals Identifies 134 Loci Associated with Somatoform Traits
Christal N. Davis, Sylvanus Toikumo, Alexander Samir Hatoum, Yousef Khan, Benjamin K. Pham, Shreya Reddy Pakala, Kyra L. Feuer, Joel E. Gelernter, Sandra Sanchez‐Roige, Rachel L. Kember et al. · 2024 · Research Square
The relationship between variation in genes, GABA, structureand gamma oscillations in the visual and auditory system ofhealthy individuals and psychiatric disorder
Jennifer Brealy · 2015 · ORCA Online Research @Cardiff (Cardiff University)
Nicotine Dependence – Identifying the Contribution of Specific Genes
Jenni Hällfors · 2017 · Työväentutkimus Vuosikirja
The Big Picture: Systems Biology Approach to Antiepileptic Drug Discovery
Jennifer A. Kearney · 2017 · Epiliepsy currents/Epilepsy currents
GLRB variants regulate nearby gene expression in human brain tissues
Qingjian Wu, Mingfeng Yang, Pi‐da Hao, Chengjun Yan, Chunjing Du, Jianhua Li, Ya‐Jun Hou, Bao‐liang Sun, Shuyin Sun · 2017 · Scientific Reports
High genetic loading of schizophrenia predicts poor response to lithium in patients with bipolar disorder: A polygenic score and cross-trait genetic analysis
Azmeraw T. Amare, Klaus Oliver Schubert, Liping Hou, Scott Richard Clark, Sergi Papiol, Urs Heilbronner, Franziska Degenhardt, Fasil Tekola Ayele, Yi‐Hsiang Hsu, Tatyana Shekhtman et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
Integrating Genome-Wide Association and Blood Genomic Profiling Data to Characterise Migraine Risk Loci
Zachary F. Gerring · 2017 · Queensland University of Technology
Association and interplay of genetic and epigenetic variants in smoking behavior
Richa Gupta · 2018 · Työväentutkimus Vuosikirja
A Multiplexed Assay for Exon Recognition Reveals That an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Disruptions to Splicing
Rocky Cheung, Kimberly D. Insigne, David Yao, Christina P. Burghard, Eric M. Jones, Daniel Bryan Goodman, Sriram Kosuri · 2018 · SSRN Electronic Journal
Prodromal Variability in Huntington's Disease Progression and Resistance
Jennifer Ciarochi · 2022 · Digital Archive @ GSU
Partitioning the genetic architecture of amyotrophic lateral sclerosis
Iris Broce, Chun Chieh Fan, Nicholas T. Olney, Catherine Lomen‐Hoerth, Steven M. Finkbeiner, Nazem Atassi, Merit Cudkowicz, Sabrina Paganoni, Jennifer S. Yokoyama, Aimee W. Kao et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Functional Characterisation of a GWAS Risk Locus Identifies GPX3 as a Lead Candidate Gene in ALS
Restuadi Restuadi, Frederik J. Steyn, Edor Kabashi, Shyuan Thieu Ngo, Feifei Cheng, Marta F. Nabais, Michael James Thompson, Ting Qi, Anjali K. Henders, Leanne M. Wallace et al. · 2020 · SSRN Electronic Journal
NeuroSCORE: A Genome-wide Omics-Based Model to Identify Candidate Disease Genes of the Central Nervous System
Kyle Davis, Colleen G. Bilancia, Megan M. Martin, Rena J. Vanzo, Megan Rimmasch, Yolanda Hom, Mohammed J. Uddin, Moises A. Serrano · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Discovery-Based Transcriptome and Translatome Profiling Reveals Molecular Pathways in the Pathogenesis of Alzheimer’s Disease
Paul M. McKeever · 2018 · TSpace (University of Toronto)
A genetic and transcriptomic assessment of the KTN1 gene in Parkinson’s disease risk
Anni K. Moore, Sara Bandrés‐Ciga, Cornelis Blauwendraat, Mónica Díez-Fairén · 2021 · medRxiv
IL-6R Protective Variant rs7529229 Reduces Interleukin-6 Signaling and Contributes To A Decreased Ischemic Stroke Risk
Haihua Zhang, Wenbo Zhao, Bian Liu, Tao Wang, Zhifa Han, Xunming Ji, Guiyou Liu · 2020
Genetic regulation of gene expression in brain and blood
Niek de Klein · 2021
Faculty Opinions recommendation of Prioritizing Parkinson's disease genes using population-scale transcriptomic data.
Melanie Bahlo · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Faculty Opinions recommendation of Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk.
Chao Cheng · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature