Cell type- and brain region-resolved mouse brain proteome
Sharma, Kirti, Schmitt, Sebastian, Bergner, Caroline G, Tyanova, Stefka, Kannaiyan, Nirmal, Manrique-Hoyos, Natalia, Kongi, Karina, Cantuti, Ludovico +5 more·2015·Nature Neuroscience
DOI 10.1038/nn.4160
Cited by (818)
Items 701–800 of 818
- Loss of Mitochondrial Tusc2/Fus1 Triggers a Brain Proinflammatory Microenvironment and Early Spatial Memory ImpairmentTonie Farris, Salvador González Ochoa, Muna A. Mohammed · 2024 · Preprints.org
- Efficient integration of spatial omics data for joint domain detection, matching, and alignment with stMSAHan Shu, Jing Chen, Chang Xu · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Nomination of a novel plasma protein biomarker panel capable of classifying Alzheimer’s disease dementia with high accuracy in an African American cohortLindsey A. Kuchenbecker, Kevin J. Thompson, Cheyenne D. Hurst, Bianca M. Opdenbosch, Michael G. Heckman, Joseph S. Reddy, Thuy Nguyen, Heidi L. Casellas, Katie D. Sotelo, Delila J. Reddy et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Benchmarking macaque brain gene expression for horizontal and vertical translation2024
- Proteomic characterization of neuronal extracellular vesicle interactomes in Alzheimer’s disease mouse model through TurboID-based proximity labelingBrendan J. Gibbs, Yunfei Chen, Mohammad Abdullah, S. Nguyen, James McQuaker-Kajiwara, Bridgette C. Melvin, Alejandro Longtree‐Preciado, Zhewei Liang, Maria Paz Gonzalez-Perez, Seiko Ikezu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- CNS Myelin Sheath Lengths Locally Scale to Axon Diameter via Piezo1Amanda R. Young, Ryan W. Lewis, Martha Cash, Beckam Polis, Myah Zalusky, Jacob Reyngoudt, A.V. Datta, Marie E. Bechler · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Integration of RNA and protein expression profiles to study human cellsFrida Danielsson · 2016 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
- The role of astrocytes in murine models of toxic demyelinationLena Menken · 2016
- Uncovering Key Neurons for Manipulation in MammalsBoris V. Zemelman · 2017 · Cambridge University Press eBooks
- Brain Proteomics: Decoding Neuroproteomes Using Mass SpectrometryJoaquín Fernández‐Irigoyen, Enrique Santamaría · 2017 · Neuromethods
- Organellar Proteomics: Tissue Specificity, Absolute Quantity, Posttranslational Modifications and Protein-Protein InteractionsMoussa AE, Xueshan Chen · 2017 · Journal of Data Mining in Genomics & Proteomics
- Development of a multiplexed RNAi-coupled sensor assay to study neuronal function on the large-scaleAlexander Herholt · 2017
- Glutathione S -transferases: unexpected roles in astrocyte activation and astrocyte-microglia communication during brain inflammationShin‐ichi Kano, Eric Y. Choi, Eisuke Dohi, Indigo V.L. Rose, Daniel J. Chang, Ashley M. Wilson, Brian D. Lo, Takashi Imai, Akira Sawa · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Making brain proteomics true to typeRashaun S. Wilson, Angus Clark Nairn · 2018 · Nature Biotechnology
- Contribution of Piezo1 mechanosensitive channels to astrocyte calcium signalingRebecca W.Y. Ko · 2018 · cIRcle (University of British Columbia)
- Molecular origins of tissue vulnerability to aberrant aggregation in protein misfolding diseasesRosie Freer · 2018 · Apollo (University of Cambridge)
- The translatome of adult cortical axons is regulated by learning in vivoLinnaea E. Ostroff, Emanuela Santini, Robert M. Sears, Zachary Deane, Joseph E. LeDoux, Tenzin W. Lhakhang, Aristotelis Tsirigos, Adriana Heguy, Eric Klann · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Large-scale proteomic analysis of human prefrontal cortex identifies proteins associated with cognitive trajectory in advanced ageAliza P. Wingo, Eric B. Dammer, Michael S. Breen et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Novel CDKL5 substrates and functions in neurodevelopmentLucas L. Baltussen · 2018 · UCL Discovery (University College London)
- Identification of a unique oligodendrocyte subpopulation in mouse brainM. Khojasteh-Fard · 2018
- Surfaceome dynamics during neuronal development and synaptic plasticity reveal system-wide surfaceome reorganization independent of global proteostasisMarc van Oostrum, Benjamin F. N. Campbell, Maik Müller · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Mapping the cell-surface proteome underlying hippocampal mossy fiber synapse identityNuno Apóstolo, Samuel N. Smukowski, Julie Vanderlinden, Giuseppe Condomitti, Vasily Rybakin, Jolijn ten Bos, Sybren Portegies, Kristel M. Vennekens, Natalia V. Gounko, Keimpe D. B. Wierda et al. · 2019 · Greater South Information System
- Neuron Type-Specific Translatomes in Spinal Cords of Naïve and Neuropathic MiceRebecca R Das Gupta, Louis Scheurer, Paweł Pelczar, William T. Ralvenius, Hendrik Wildner, Hanns Ulrich Zeilhofer · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Proteomics and Metabolomics in PainManuela Schmidt · 2020 · Elsevier eBooks
- DIAFree enables untargeted open-search identification for Data-Independent Acquisition dataXinyi Xu · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- In-depth analysis of proteomic and genomic fluctuations during the time course of human embryonic stem cells directed differentiation into beta cellsBogdan Budnik, Juerg Straubhaar, John M. Neveu · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Temporal proteomic profiling of postnatal human cortical developmentMichael S. Breen, Süreyya Özcan, Jordan M. Ramsey et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- A global multiregional proteomic map of the human cerebral cortexZhengguang Guo, Chen Shao, Yang Zhang et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Specialty Grand Challenge for Molecular Signalling and Pathways in Molecular NeuroscienceJean‐Marc Taymans · 2021 · Frontiers in Molecular Neuroscience
- Retrieve and Revise: Improving Peptide Identification with Similar Mass SpectraZhengcong Fei · 2021 · Proceedings of the AAAI Conference on Artificial Intelligence
- Expression of a modified astrocytic glutamate transporter alleviates Huntington’s hypokinesia, promotes synaptic glutamate clearance and counteracts potentially adverse EAAT2 interactionsStefan Hirschberg, Anton Dvorzhak, Seyed M. A. Rasooli-Nejad · 2021 · MDC Repository (Max-Delbrueck-Center for Molecular Medicine)
- Biomarker Development of Intraductal Papillary Mucinous Neoplasm and Breast Cancer using Quantitative Proteomics and Bioinformatics도미솔 · 2021 · Seoul National University Open Repository (Seoul National University)
- UT's Project Quest Reaches Deep into Instruction and ResearchWayne A. Danielson · 1988 · T.H.E. Journal Technological Horizons in Education
- Evaluation of process parameters used in the non-aqueous anodization of aluminum alloysJanda K. G. Panitz, D.J. Sharp, Dean E. Peterson · 1982 · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
- Cryo-section Dissection of the Adult Subependymal Zone for Accurate and Deep Quantitative Proteome AnalysisChristian Friess, Magdalena Götz, Jacob Kjell · 2021 · Journal of Visualized Experiments
- Validating amino acid variants in proteogenomics using sequence coverage by multiple readsLev I. Levitsky, Ksenia G. Kuznetsova, Anna A. Kliuchnikova et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Multi-omic analysis of the aging mouse brainVerena Kluever · 2021
- Faculty Opinions recommendation of Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution.Sharyn A. Endow · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Metabolically induced neuronal differentiationSandy Maurer · 2022
- Species-specific cutaneous protein signatures upon incision injury and correlation with distinct pain-related phenotypes in humansDaniel Segelcke, Max van der Burgt, Christin Kappert, Daniela Schmidt Garcia, Julia Regina Sondermann, Stephan Bigalke, Bruno Pradier, David Gómez‐Varela, Peter K Zahn, Manuela Schmidt et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Faculty Opinions recommendation of In vivo brain GPCR signaling elucidated by phosphoproteomics.Arun K. Shukla · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Elucidation of the mechanism of cognitive decline in mild cognitive impairment using causal discoveryKenji Matsuura · 2022 · Medicine and Clinical Science
- Análisis proteómico de la respuesta protectora mediada por el esteroide sintético Tibolona frente a un insulto lipotóxico en astrocitos humanosDiego Julián Vesga-Jiménez · 2021
- Prospects of Single Cell Omics (SCO) Analysis for Investigating Nervous System DisordersMuhammad Qasim Khan, Syeda Marriam Bakhtiar · 2022 · Current Trends in OMICS
- Zur Regulation des oxidativen Energiemetabolismus in Astrozyten: Darstellung einer mGluR5/ PKCδ - vermittelten Aktivierung von Mitochondrien in vitroKiavasch Mohammad Nejad Farid · 2023
- Data from Leukotriene Synthesis Is Critical for Medulloblastoma ProgressionFang Du, Larra W. Yuelling, Eric H. Lee, Yuan Wang, Shengyou Liao, Yan Cheng, Li Zhang, Chaonan Zheng, Suraj Peri, Kathy Qi Cai et al. · 2023
- Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injuryDario Lucas Helbing, Fabienne Haas, Emilio Cirri · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Brain cell type specific proteomics approach to discover pathological mechanisms in the childhood CNS disorder mucolipidosis type IVMadison Sangster, Sanjid Shahriar, Zachary Niziolek · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Proteomic characterization of aging-driven changes in the mouse brain by co-expression network analysisKazuya Tsumagari, Yoshiaki Sato, Hirofumi Aoyagi · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Cell-type-specific neuroproteomics of synapsesYun Young Yim, Eric J. Nestler · 2023 · Preprints.org
- Profiling the neuroimmune cascade in 3xTg mice exposed to successive mild traumatic brain injuriesA. Pybus, Sara Bitarafan, R. Brothers, Alivia Rohrer, Arushi Khaitan, F. R. Moctezuma, K. Udeshi, Brae Davies, Sydney E. Triplett, E. Dammer et al. · 2023 · bioRxiv
- Brain map of aging-induced alterations in membrane ganglioside patternDurga Jha, Gabriela Dovrtělová, Petr Telenský, Seweryn Olkowicz, Kateřina Coufalíková, Lukáš Opálka, Karel Kubíček, Bára Černá, Roman Hajek, Silvie Bělašková et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Integrated Multiplex Network-Based Approach for Novel Biomarker Identification in Sleep ApneaFangchao Zhao, Shujun Li · 2023 · SSRN Electronic Journal
- Biochemically-functionalized probes for cell type-specific targeting and recording in the brainAnqi Zhang, Theodore J. Zwang, Charles M. Lieber · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Tracing metabolic pathways in a spectrum of inherited diseasesMelissa H. Broeks · 2023
- Multimodal joint deconvolution and integrative signature selection in proteomicsYue Pan, Xusheng Wang, Chunyu Liu · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Variation of the 2D Pattern of Brain Proteins in Mice Infected with Taenia crassiceps ORF StrainMariana Díaz-Zaragoza, Ricardo Hernández-Ávila, Abraham Landa · 2024 · International Journal of Molecular Sciences
- Additional file 10 of BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microgliaAri Sudwarts, Supriya Ramesha, Tianwen Gao, Moorthi Ponnusamy, Shuai Wang, Mitchell T. Hansen, Alena Kozlova, Sara Bitarafan, Prateek Kumar, David Beaulieu‐Abdelahad et al. · 2023 · Figshare
- Additional file 3 of A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer’s diseaseAnnett Boeddrich, Christian Haenig, Nancy Neuendorf, Eric Blanc, Andranik Ivanov, Marieluise Kirchner, Philipp Schleumann, Irem Bayraktaroğlu, Matthias Richter, Christine Molenda et al. · 2023 · Figshare
- Additional file 4 of Differential RNA packaging into small extracellular vesicles by neurons and astrocytesXuan Luo, Renée Jean‐Toussaint, Ahmet Saçan, Seena K. Ajit · 2021 · Figshare
- Additional file 1 of Genetic architecture of protein expression and its regulation in the mouse brainAlyssa Erickson, Suiping Zhou, Luo, Jie, Ling Jing Li, Xin Huang, Zachary Even, He Huang, Haiming Xu, Junmin Peng, Lu, Lu et al. · 2021 · Figshare
- Additional file 5 of Differential RNA packaging into small extracellular vesicles by neurons and astrocytesXuan Luo, Renée Jean‐Toussaint, Ahmet Saçan, Seena K. Ajit · 2021 · Figshare
- Additional file 6 of Differential RNA packaging into small extracellular vesicles by neurons and astrocytesXuan Luo, Renée Jean‐Toussaint, Ahmet Saçan, Seena K. Ajit · 2021 · Figshare
- Additional file 3 of Differential RNA packaging into small extracellular vesicles by neurons and astrocytesXuan Luo, Renée Jean‐Toussaint, Ahmet Saçan, Seena K. Ajit · 2021 · Figshare
- Generation of a Deep Mouse Brain Spectral Library for Transmembrane Proteome Profiling in Mental Disease ModelsShanshan Li, Huoqing Luo, Pan Tang, Cuiping Tian, Ji Hu, Haojie Lu, Wenqing Shui · 2024 · Molecular & Cellular Proteomics
- Characterization of Spinal Cord Tissue-derived Extracellular Vesicles in NeuroinflammationLarissa Jank, Ajay Kesharwani, Taekyung Ryu et al. · 2024 · Research Square
- Developmental and age-related synapse elimination is mediated by glial CroquemortTaylor R. Jay, Yunsik Kang, Victor Ouellet-Massicotte · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Multi-Omics Association Study Identifies New Potential Prostate Cancer- Causing GeneXinlong Wang, Aimin Jiang, Jiaming Shen, Lei Wang, zhiyong liu · 2024 · Research Square
- Phosphoproteomic analysis reveals CDK5-Mediated phosphorylation of MTDH inhibits protein synthesis in microgliaJian Shen, Xuyang Zhao, Xue Bai, Wenyuan Zhu, Zeyang Li, Zihao Yang, Qingsong Wang, Jianguo Ji · 2024 · Biochemical and Biophysical Research Communications
- Cell type-Specific In Vivo Proteomes with a Multi-copy Mutant Methionyl t-RNA Synthetase Mouse LineRodrigo Alvarez-Pardo, Susanne tom Dieck, Kristina Desch, Belquis Nassim-Assir, Cristina Olmedo Salinas, Riya S. Sivakumar, Julian D. Langer, Beatriz Alvarez‐Castelao, Erin Margaret Schuman · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Spatial-DC: a robust deep learning-based method for deconvolution of spatial proteomicsYuan Li, Qian Kong, Zihan Wu, Yanfen Xu, Yiheng Mao, Yunjie Gu, Xi Wang, Weina Gao, Ruijun Tian, Jianhua Yao · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- MODE: high-resolution digital dissociation with deep multimodal autoencoderJiao Sun, Ayesha A. Malik, Tong Lin, Ayla Bratton, Yue Pan, Kyle Smith, Arzu Onar‐Thomas, Giles W. Robinson, Wei Zhang, Paul A. Northcott et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Absolute Quantification of Lysosomal Proteins by Multiple Reaction Monitoring Mass Spectrometry and QconCAT Protein StandardsPeter Mosen, Biswajit Moharana, Sofía Fajardo‐Callejón, Edgar Kaade, Norbert Rösel, Maryam Omidi, Roman Sakson, Thomas Ruppert, Sandra Pohl, Volkmar Gieselmann et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Identification of Mood Disorders Causal Genes by Integrating the Brain Proteome and TranscriptomeRong-kun Zhu, Hong-jian Zhou, Jun Shi, Ling Ge, Yi Lin, Wen-hao Yin, Hui Zeng, Xiongwei Wang · 2025 · Molecular Neurobiology
- Dynamic Proteome Changes in Cuprizone-Induced Demyelination and Remyelination in the Mouse BrainRong-Fang Gu, Xiaoping L. Hronowski, Zhaohui Shao, Benbo Gao, Kayla Soucey, Fangxu Sun, Hui‐Hsin Tsai, Ru Wei · 2025 · Journal of Proteome Research
- Identification of novel drug targets through integrative PWAS of brain and plasma proteins with Ulcerative Colitis GWASNingning Liu, Yi Hou, Miao Yu · 2025 · PLoS ONE
- A reciprocal interplay between 5-HT 2A and mGlu 5 receptors underlies neuroplasticityTomas del Olmo, Mathilde Decourcelle, Martial Sevéno, Joël Bockaert, Philippe Marin, Carine Bécamel · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Brain Mecp2 Gene Dosage and Gene Therapy Shape Multi-Omic Signatures and Putative Biomarkers in Rett SyndromeStephanie A. Zlatic, Eric B. Dammer, Amanda J. Crocker, Duc M. Duong, Jim Selfridge, Kamal K.E. Gadalla, Avanti Gokhale, Brendan R. Tobin, Levi Benjamin Wood, Martina Zandl‐Lang et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Multi-omics analysis indicates an association between TAPBP and prostate cancerXinlong Wang, Aimin Jiang, Chao Li, Zhiyong Liu · 2025 · PLoS ONE
- Ependymoma group-specific blood-brain barrier differences uncovered by a multi-omics approachJulia K. Sundheimer, Julia Benzel, Aniello Federico et al. · 2026 · Research Square
- Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male MiceYang Zhou, Yitong Lu, Zhaobao Wang, Xiaoqian Du, Bei Jiang, Qiuhui Xuan · 2026 · The FASEB Journal
- Cell type-resolved proteomics reveals intra- and intercellular signaling in Alzheimer’s diseaseXue Zhang, Kaiwen Yu, Him K. Shrestha, Ying Zhou, Jiyuan Yang, Zhen Wang, Xiaokang Ren, Ping-Chung Chen, Huan Sun, Danting Liu et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Astrocytes are necessary for blood–brain barrier maintenance in the adult mouse brainBenjamin P. Heithoff, Kijana K. George, Aubrey N. Phares · 2020 · Maryland Shared Open Access Repository (USMAI Consortium)
- Sex-specific changes in the hippocampal proteome of Negr1−/− mice: insight into the mechanisms of neuropsychiatric disordersSrirathi Muthuraman, Mohan Jayaram, Liisi Promet, Toomas Jagomäe, Arun Kumar Devarajan, Andreas-Christian Hade, Mari‐Anne Philips, Katyayani Singh, Eero Vasar · 2026 · Biology of Sex Differences
- Les astrocytes réactifs, des partenaires anti-agrégants dans la maladie de Huntington : identification des mécanismes impliqués dans le dialogue neurone-astrocyteLaurene Abjean · 2019 · theses.fr (ABES)
- Etude de la réponse différenciée à l'hypoxie-ischémie au cours du développement cérébral périnatal chez la sourisNicolas Dupré · 2019 · theses.fr (ABES)
- DNAJC6 Parkinson’s disease: Endolysosomal dysfunction and emerging roles for oligodendrocytesAngel G Allen, Sarah J. Stednitz, Michael T. Lardelli, Karissa Barthelson · 2026 · npj Parkinson s Disease
- Étude moléculaire de l'inflammation chronique dans la maladie de ParkinsonAnne‐Claire Compagnion · 2019 · theses.fr (ABES)
- Hétérogénéité de la réactivité astrocytaire dans la maladie d'AlzheimerOcéane Guillemaud · 2020 · theses.fr (ABES)
- Étude du rôle de la microglie dans la propagation de la protéine Tau : mise en place de nouveaux modèlesCharlotte Duwat · 2021 · theses.fr (ABES)
- Ultrastructural and molecular analysis of cortico-striatal dopamine hub synapsesPaul Lapios · 2024 · theses.fr (ABES)
- Synaptic plasticity in a memory circuit : physiological and pathophysiological role of the amyloid precursor proteinAna Moreira-de-Sá · 2024 · theses.fr (ABES)
- PAK1 and NF2 antagonist functions in regulating central nervous system myelination : from modulation of oligodendrocyte cytoskeleton to myelin sheath formationNoémie Adès · 2024 · theses.fr (ABES)
- Rôle de la protéine de densité post-synaptique 95 (PSD-95) dans la myélinisation du système nerveux centralMauricio Lopez Portillo Masson · 2024 · theses.fr (ABES)
- Sequestration of growth cone surface proteins by cytoplasmic Lrrtm2 induces de novo amygdala innervation by cerebral cortex associative neuronsDustin E. Tillman, Omer Durak, Priya Veeraraghavan, John E. Froberg, George C. Wheeler, Bogdan Budnik, Jeffrey D. Macklis · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Characterization and quantification of proteins involved in neurodegenerative diseases by mass spectrometryKim Thanh Van · 2025 · theses.fr (ABES)
- Ependymoma group-specific blood-brain barrier differences uncovered by a multi-omics approachJulia K. Sundheimer, Julia Benzel, Aniello Federico et al. · 2026 · Scientific Reports
- Nutritional supplementation remodels yak cardiac molecular networks through selenoprotein activation and immune quiescenceYiqun Chen, Chaoyun Yang, Tao Li · 2026 · Frontiers in Nutrition
- Neurotransmitter-activated GPCR signaling in myelin plasticityMarta Cimadevila, Carlos Matute · 2026 · Trends in Molecular Medicine
- APOE4 Drives Sex‐ and Diet‐Dependent Effects on AD ‐Like Pathology, Cognition, and Mitochondrial FunctionChelsea N. Johnson, Colton R Lysaker, Xin Cao, Vivien Csikós, Frederick B. Boakye, Paul J. Kueck, Edziu Franczak, Paige C. Geiger, Jill K. Morris, John P. Thyfault et al. · 2026 · FASEB BioAdvances