Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

Durak, Omer, Gao, Fan, Kaeser-Woo, Yea Jin, Rueda, Richard, Martorell, Anthony J, Nott, Alexi, Liu, Carol Y, Watson, L Ashley +1 more·2016·Nature Neuroscience

Cited by (236)

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  9. Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model
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  10. Chd8 regulates X chromosome inactivation in mouse through fine-tuning control of Xist expression
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  11. Loss of autism-candidate CHD8 perturbs neural crest development and intestinal homeostatic balance
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  13. Autism Spectrum Disorder Genes: Disease-Related Networks and Compensatory Strategies
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  14. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1
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  15. Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex
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  17. Multiple roles of Ulk4 in neurogenesis and brain function
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  18. Neurodevelopmental functions of CHD8: new insights and questions
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  19. The CHD Protein, Kismet, is Important for the Recycling of Synaptic Vesicles during Endocytosis
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  20. CHD8short, a naturally-occurring truncated form of a chromatin remodeler lacking the helicase domain, is a potent transcriptional coregulator
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  21. The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function
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  25. CHD8 regulates gut epithelial cell function and affects autism-related behaviors through the gut-brain axis
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  34. RETRACTED ARTICLE: Overexpression of microRNA-221 promotes the differentiation of stem cells from human exfoliated deciduous teeth to neurons through activation of Wnt/β-catenin pathway via inhibition of CHD8
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  37. Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice
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  52. Natural SINEUP RNAs in Autism Spectrum Disorders: RAB11B-AS1 Dysregulation in a Neuronal CHD8 Suppression Model Leads to RAB11B Protein Increase
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  56. Sequencing of selected chromatin remodelling genes reveals increased burden of rare missense variants in ASD patients from the Japanese population
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  57. Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome
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