Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

Cited by (224)

Items 201–224 of 224

1. Additional file 5 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
   Matan Sorek, Walaa Oweis, Malka Nissim‐Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
2. Additional file 2 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
   Matan Sorek, Walaa Oweis, Malka Nissim‐Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
3. Additional file 4 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
   Matan Sorek, Walaa Oweis, Malka Nissim‐Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
4. Additional file 3 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
   Matan Sorek, Walaa Oweis, Malka Nissim‐Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
5. Epigenetics and pharmacoepigenetics of age-related neurodegenerative disorders
   Ramón Cacabelos, Olaia A. Martínez-Iglesias, Natalia Cacabelos, Pablo Cacabelos, Vinogran Naidoo · 2025 · Elsevier eBooks
6. Screening of a kinase inhibitor library in human Huntington’s disease iPSC-derived striatal precursor neurons reveals a neuroprotective effect of PKC-α/β1 inhibition
   Mali Jiang, Tianze Shi, Ritika Miryala, Matthew Rodriguez, Ronald S. Wang, Rashi Sultania, Lauren C. Guttman, Julia Johnston, Louisa Mulligan, Yushan Li et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
7. Childhood to Adult Neurodevelopment in Gene-Expanded Huntington’s Disease (ChANGE-HD) study protocol: A Prospective Longitudinal Neurodevelopmental Study of Huntington’s Disease
   Mohit Neema, Nabil M Halabi, Peg Nopoulos, Michael Freedberg, the ChANGE-HD investigators, coordinators, and consultants · 2025 · medRxiv
8. Additional file 1 of Elevated SLC7A2 expression is associated with an abnormal neuroinflammatory response and nitrosative stress in Huntington’s disease
   Ian D. Gaudet, Hongyuan Xu, Gordon, Emily, Gianna Adalia Cannestro, Michael L. Lu, Wei, Jianning · 2024 · Figshare
9. Additional file 6 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
   Matan Sorek, Walaa Oweis, Nissim-Rafinia, Malka, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
10. Additional file 1 of Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity
    Matan Sorek, Walaa Oweis, Nissim-Rafinia, Malka, Moria Maman, Shahar Simon, Cynthia C. Hession, Xian Adiconis, Sean Simmons, Neville E. Sanjana, Xi Shi et al. · 2021 · Figshare
11. Mouse models to interrogate the developmental pathogenesis of Huntington's disease
    Yagiz Altun, Siyu Yan, Kevin Zheng, Aldrín E. Molero, Mark F. Mehler · 2026 · Journal of Huntington s Disease
12. Contribution of neuroepigenetics to HD – developmental and aging-related signatures
    Jil Scuto, Noémie Penaud, Karine Mérienne · 2026 · Journal of Huntington s Disease
13. Abnormal cortical development sets the stage in Huntington disease
    Marine Degennaro, Sandrine Humbert, Mariacristina Capizzi · 2026 · Journal of Huntington s Disease
14. Towards Trans-Splicing Gene Therapy for HD : Intronic Targets Identification in the Huntingtin Gene
    Séverine Maire · 2018
15. The role of the serum response factor in the pathogenesis of Huntington's disease
    Ali Awada · 2021 · theses.fr (ABES)
16. Déficits développementaux du circuit striatal chez des modèles murins de la maladie de Huntington
    Margaux Lebouc · 2023 · theses.fr (ABES)
17. Functional impacts of Huntingtin lowering on the synaptic maturation and activity of neuronal networks derived from human induced pluripotent stem cells
    Mathilde Louçã · 2024 · theses.fr (ABES)
18. Towards AI-driven prediction of HTT CAG size in super-expanded human spiny projection neurons from Huntington disease donors
    Simone Maestri, Davide Scalzo, Martina Zobel, Dario Besusso, Elena F. Cattaneo · 2026 · Journal of Huntington s Disease
19. Development-related gene expression disruption in the human midcingulate cortex in Huntington's disease
    Shelly Scheepers, Mackenzie Wendy Ferguson, Thulani Hansika Palpagama, Aodán Laighneach, Derek W. Morris, Deborah Young, CLINTON TURNER, Lynette J. Tippett, Henry John Waldvogel, Richard L. M. Faull et al. · 2026 · Journal of Huntington s Disease
20. Modeling striatal development and disease with human pluripotent stem cells
    Sopak Supakul, Yuya Sasaki, Kosuke Karasawa, Yoshitaka Kase, Mitsuru Ishikawa, Hideyuki Okano · 2026 · Inflammation and Regeneration
21. Childhood to Adult Neurodevelopment in Gene-Expanded Huntington’s Disease (ChANGE-HD): A prospective longitudinal neurodevelopmental study of Huntington’s disease
    Mohit Neema, Nabil M Halabi, Peg Nopoulos, Michael Freedberg, the ChANGE-HD investigators, coordinators, and consultants · 2026 · PLoS ONE
22. Functional and Transcriptional Downregulation of Glutamate Transporters (EAAT1 and EAAT2) via DNMT3B Overexpression in Glial Cells
    Jaqueline Loaeza‐Loaeza, Ada G. Rodríguez-Campuzano, Luisa C. Hernández‐Kelly, Daniel Hernández‐Sotelo, Marie‐Paule Felder‐Schmittbuhl, Arturo Ortega · 2026 · Molecular Neurobiology
23. Dysfunction of Primary Cilium in Huntington’s Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub
    Aleksandra Sergeevna Churkina, Anton Sergeevich Shakhov, Irina Borisovna Alieva · 2026 · Biochemistry (Moscow)
24. Expanded Polyglycine Protein Aggregates Alter the RNA Splicing Profile into a Premature State Partially via Sequestering SF3B4
    Jiaxin Yang, Youqi Zheng, Jianyi Hu, Yanzhen Wu, Xin Yang, Peihan Chai, Zhaolin Zhang, Shiping Zhang, Qiong Liu, Yongcheng Pan et al. · 2026 · Neuroscience Bulletin