Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1
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Localized translation from mRNAs is mediated in part by mRNA binding proteins that promote translation.
“Localized translation from mRNAs is mediated in part by mRNA binding proteins that promote translation [59,60] and a counterpart to this could be that miRNAs clear mRNAs at sites where protein activity should be low.”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [60]
The translation of beta-actin in neuronal processes is regulated by Vg1RBP, a protein that binds the 3' UTR of mRNAs.
“It is intriguing that the translation of beta-actin in neuronal processes is regulated by Vg1RBP, a protein that binds the 3' UTR of mRNAs [60] and may, therefore, shield the mRNA from miRNAs.”
From MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system (2007) · cites this paper as [60]
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- [1]Henley J Poo MM Guiding neuronal growth cones using Ca2+ signals Trends Cell Biol 2004 14 320 30 15183189 PMC3115711
- [2]Guirland C Suzuki S Kojima M Lu B Zheng JQ Lipid rafts mediate chemotropic guidance of nerve growth cones Neuron 2004 42 51 62 15066264
- [3]Wen Z Guirland C Ming GL Zheng JQ A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidance Neuron 2004 43 835 46 15363394
- [4]Zheng JQ Turning of nerve growth cones induced by localized increases in intracellular calcium ions Nature 2000 403 89 93 10638759
- [5]Li Y Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor Nature 2005 434 894 8 15758952
- [6]Lohof AM Quillan M Dan Y Poo MM Asymmetric modulation of cytosolic cAMP activity induces growth cone turning J Neurosci 1992 12 1253 61 1372932 PMC6575801
- [7]Ming GL Adaptation in the chemotactic guidance of nerve growth cones Nature 2002 417 411 8 11986620
- [8]Piper M Signaling mechanisms underlying slit2-induced collapse of Xenopus retinal growth cones Neuron 2006 49 215 28 16423696 PMC3689199
- [9]Wu KY Local translation of RhoA regulates growth cone collapse Nature 2005 436 1020 4 16107849 PMC1317112
- [10]Campbell DS Holt CE Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation Neuron 2001 32 1013 26 11754834
- [11]Shestakova EA Singer RH Condeelis J The physiological significance of beta-actin mRNA localization in determining cell polarity and directional motility Proc Natl Acad Sci U S A 2001 98 7045 50 11416185 PMC34620
- [12]Bassell GJ Sorting of beta-actin mRNA and protein to neurites and growth cones in culture J Neurosci 1998 18 251 65 9412505 PMC6793411
- [13]Willis D Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons J Neurosci 2005 25 778 91 15673657 PMC6725618
- [14]Zhang HL Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility Neuron 2001 31 261 75 11502257
- [15]Zhang HL Singer RH Bassell GJ Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones J Cell Biol 1999 147 59 70 10508855 PMC2164987
- [16]Yuan XB Signalling and crosstalk of Rho GTPases in mediating axon guidance Nat Cell Biol 2003 5 38 45 12510192
- [17]Gebauer F Hentze MW Molecular mechanisms of translational control Nat Rev Mol Cell Biol 2004 5 827 35 15459663 PMC7097087
- [18]Kloc M Zearfoss NR Etkin LD Mechanisms of subcellular mRNA localization Cell 2002 108 533 44 11909524
- [19]Condeelis J Singer RH How and why does beta-actin mRNA target? Biol Cell 2005 97 97 110 15601261
- [20]Huttelmaier S Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1 Nature 2005 438 512 5 16306994
- [21]Yisraeli JK VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins Biol Cell 2005 97 87 96 15601260
- [22]Sundell CL Singer RH Requirement of microfilaments in sorting of actin messenger RNA Science 1991 253 1275 7 1891715
- [23]Lopez de Heredia M Jansen RP mRNA localization and the cytoskeleton Curr Opin Cell Biol 2004 16 80 5 15037309
- [24]Deiner MS Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia Neuron 1997 19 575 89 9331350
- [25]Campbell DS Semaphorin 3A elicits stage-dependent collapse, turning, and branching in Xenopus retinal growth cones J Neurosci 2001 21 8538 47 11606642 PMC6762807
- [26]Hopker VH Shewan D Tessier-Lavigne M Poo M Holt C Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1 Nature 1999 401 69 73 10485706
- [27]Takei N Kawamura M Hara K Yonezawa K Nawa H Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin J Biol Chem 2001 276 42818 25 11551908
- [28]Wilkie GS Dickson KS Gray NK Regulation of mRNA translation by 5′- and 3′-UTR-binding factors Trends Biochem Sci 2003 28 182 8 12713901
- [29]Ando R Hama H Yamamoto-Hino M Mizuno H Miyawaki A An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein Proc Natl Acad Sci U S A 2002 99 12651 6 12271129 PMC130515
- [30]de la Torre JR Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC Neuron 1997 19 1211 24 9427245
- [31]Gingras AC Hierarchical phosphorylation of the translation inhibitor 4E-BP1 Genes Dev 2001 15 2852 64 11691836 PMC312813
- [32]Eng H Lund K Campenot RB Synthesis of beta-tubulin, actin, and other proteins in axons of sympathetic neurons in compartmented cultures J Neurosci 1999 19 1 9 9870932 PMC6782370
- [33]Ooashi N Futatsugi A Yoshihara F Mikoshiba K Kamiguchi H Cell adhesion molecules regulate Ca2+-mediated steering of growth cones via cyclic AMP and ryanodine receptor type 3 The Journal of Cell Biology 2005 170 1159 16172206 PMC2171540
- [34]Kuhn TB Brown MD Wilcox CL Raper JA Bamburg JR Myelin and collapsin-1 induce motor neuron growth cone collapse through different pathways: inhibition of collapse by opposing mutants of rac1 J Neurosci 1999 19 1965 75 10066250 PMC6782563
- [35]Hansen WJ Cowan NJ Welch WJ Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins J Cell Biol 1999 145 265 77 10209023 PMC2133115
- [36]Wang J Reversible glutathionylation regulates actin polymerization in A431 cells J Biol Chem 2001 276 47763 6 11684673
- [37]Kislauskis EH Zhu X Singer RH beta-Actin messenger RNA localization and protein synthesis augment cell motility J Cell Biol 1997 136 1263 70 9087442 PMC2132521
- [38]Lewis AK Bridgman PC Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity The Journal of Cell Biology 1992 119 1219 1447299 PMC2289720
- [39]Oleynikov Y Singer RH Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization Curr Biol 2003 13 199 207 12573215 PMC4765734
- [40]Rousseau D Kaspar R Rosenwald I Gehrke L Sonenberg N Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E Proc Natl Acad Sci U S A 1996 93 1065 70 8577715 PMC40031
- [41]Brunet I The transcription factor Engrailed-2 guides retinal axons Nature 2005 438 94 8 16267555 PMC3785142
- [42]Kanai Y Dohmae N Hirokawa N Kinesin transports RNA: isolation and characterization of an RNA-transporting granule Neuron 2004 43 513 25 15312650
- [43]Liu G Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction Nat Neurosci 2004 7 1222 32 15494732 PMC2266630
- [44]Fan J Raper JA Localized collapsing cues can steer growth cones without inducing their full collapse Neuron 1995 14 263 7857638
- [45]Shirasaki R Mirzayan C Tessier-Lavigne M Murakami F Guidance of circumferentially growing axons by netrin-dependent and -independent floor plate chemotropism in the vertebrate brain Neuron 1996 17 1079 88 8982157
- [46]Zhang Q Vg1 RBP intracellular distribution and evolutionarily conserved expression at multiple stages during development Mech Dev 1999 88 101 6 10525193
- [47]Yaniv K Fainsod A Kalcheim C Yisraeli JK The RNA-binding protein Vg1 RBP is required for cell migration during early neural development Development 2003 130 5649 61 14522877
- [48]Chang P Localization of RNAs to the mitochondrial cloud in Xenopus oocytes through entrapment and association with endoplasmic reticulum Mol Biol Cell 2004 15 4669 81 15292452 PMC519158
- [49]Blichenberg A Identification of a cis-Acting Dendritic Targeting Element in MAP2 mRNAs Journal of Neuroscience 1999 19 8818 10516301 PMC6782761
- [50]Vignali R Poggi L Madeddu F Barsacchi G HNF1(beta) is required for mesoderm induction in the Xenopus embryo Development 2000 127 1455 65 10704391
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- Authors
- Leung, K.-M., van Horck, F. P., Lin, A. C., Allison, R., Standart, N., & Holt, C. E.
- Venue
- Nature Neuroscience
- Published
- 2006-09-17
- Volume
- 9
- Issue
- 10
- Pages
- 1247-1256
- ISSN
- 1097-6256
- 1546-1726
- PMC
- PMC1997306
- Cited by
- 447
- References
- 0
- Language
- en
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