Social Play Behavior in Adolescent Rats is Mediated by Functional Activity in Medial Prefrontal Cortex and Striatum

van Kerkhof, Linda WM, Damsteegt, Ruth, Trezza, Viviana, Voorn, Pieter, Vanderschuren, Louk JMJ·2013·Neuropsychopharmacology
DOI 10.1038/npp.2013.83

Cited by (163)

Items 101–163 of 163

  1. Prenatal exposure to alcohol impairs social play behavior in adolescent male mice
    Mara Aparecida Pereira de Ávila, Rebeca M. Gonçalves, Elisandra C.C. Nascimento, Layla D.M. Cabral, Fabiana C. Vilela, Alexandre Giusti‐Paiva · 2020 · NeuroToxicology
  2. A Cross-Species Comparative Approach to Positive Emotion Disturbance
    June Gruber, Marc Bekoff · 2016 · Emotion Review
  3. Effects of Biological Sex and Stress Exposure on Ventromedial Prefrontal Regulation of Mood-Related Behaviors
    Wallace, Tyler, Myers, Brent · 2021 · Frontiers in Behavioral Neuroscience
  4. Adolescent social housing protects against adult emotional and cognitive deficits and alters the PFC and NAc transcriptome in male and female C57BL/6J mice
    Jyoti Lodha, Emily R. Brocato, McKenzie Nash, Madison M. Marcus, A. Christian Pais, Alex B. Pais, Michael F. Miles, Jennifer T. Wolstenholme · 2023 · Frontiers in Neuroscience
  5. Feel-good songs: application of a novel playback paradigm to induce a positive affective state in juvenile male Wistar rats
    Tayla J. Hammond, Sarah M. Brown, Simone Meddle, Birte Lindstrøm Nielsen, Alistair B Lawrence, Vincent Bombail · 2024 · Applied Animal Behaviour Science
  6. Roles of AMPA receptors in social behaviors
    Qi Wei Xu, Amanda Larosa, Tak Pan Wong · 2024 · Frontiers in Synaptic Neuroscience
  7. Differential alterations in brain structural network organization during addiction between adolescents and adults
    Yoonji Joo, Suji Lee, Jaeuk Hwang, Jungyoon Kim, Young-Hoon Cheon, Hyangwon Lee, Shinhye Kim, Deborah A Yurgelun-Todd, Perry Franklin Renshaw, Sujung Yoon et al. · 2022 · Psychological Medicine
  8. Social environment enrichment alleviates anxiety-like behavior in mice: Involvement of the dopamine system
    Qun Wang, Yuqian Wang, Yaoyao Tian, Yanyan Li, Jing Han, Fadao Tai, Rui Jia · 2023 · Behavioural Brain Research
  9. Basal ganglia involvement in the playfulness of juvenile rats
    Stephen M. Siviy · 2019 · Journal of Neuroscience Research
  10. Chronic modafinil administration to preadolescent rats impairs social play behavior and dopaminergic system
    Valeska Cid-Jofré, Macarena Francisca Gárate-Pérez, Philip J. Clark, Viviana Valero-Jara, Rodrigo A. España, Ramón Sotomayor‐Zárate, Gonzalo Cruz, Georgina M. Renard · 2020 · Neuropharmacology
  11. The motivation to flock correlates with vocal-social behaviors and dopamine-related gene expression in male European starlings
    Alyse N. Maksimoski, S. A. Stevenson, Brandon J. Polzin, Chang-Jiu Zhao, Elsa M Luebke, L. V. Riters · 2023 · Hormones and Behavior
  12. Adolescent CB1 receptor antagonism influences subsequent social interactions and neural activity in female rats
    Jonathan J. Simone, Jennet L. Baumbach, Jennifer McPherson, Cheryl M. McCormick · 2020 · International Journal of Developmental Neuroscience
  13. Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex
    Francesca Mottarlini, Beatrice Rizzi, Giorgia Targa, Valeria Buzzelli, Melania Di Trapano, Laura Rullo, Sanzio Candeletti, Roberto Ciccocioppo, Liana Fattore, Patrizia Romualdi et al. · 2024 · Frontiers in Psychiatry
  14. Resolving the contributions of anaesthesia, surgery, and nerve injury on brain derived neurotrophic factor expression in the medial prefrontal cortex of male rats in the CCI model of neuropathic pain
    James W.M. Kang, Kevin A. Keay, David Mor · 2017 · Journal of Neuroscience Research
  15. Adversity in early adolescence promotes an enduring anxious phenotype and increases serotonergic innervation of the infralimbic medial prefrontal cortex
    Cindy S. Tao, Prateek Dhamija, Linda Booij, Janet L. Menard · 2017 · Neuroscience
  16. From curiosity to play: re‐evaluating the evolutionary origins of play
    Sakumi Iki · 2025 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
  17. Psychostimulants and social behaviors
    Valeska Cid-Jofré, Tamara Bahamondes, Agustina Zúñiga Correa, Ivalú Ahumada Arias, Miguel Iván Reyes-Parada, Georgina M. Renard · 2024 · Frontiers in Pharmacology
  18. Comparative analysis of tickling and conspecific play in tame mice and golden hamsters
    Sarah Dagher, Darcie DeAngelo, Ren Y. Sato, Hiroaki Norimoto, Tsuyoshi Koide, Shimpei Ishiyama · 2025 · Behavioural Brain Research
  19. Modulatory effect of romantic love on value estimation and its neural mechanism
    Ying Wang, Yuting Zhang, Ying Chen, Fang Jing, Zhenni Wang, Yaru Hao, Lizhuang Yang, Ying Liu, Yifeng Zhou, Xiaochu Zhang · 2016 · Neuroreport
  20. Inhibiting social support from massage-like stroking increases morphine dependence
    M.L. Shawn Bates, Michael A. Emery, Paul Jeff Wellman, Shoshana Eitan · 2017 · Behavioural Pharmacology
  21. Animal Models to Investigate Social Support Induced Anxiety Reductions
    Sreeparna Majumdar, Elizabeth A. Lungwitz, Katharine D. Andrews, Joanna E. Chambers, William A. Truitt · 2018 · Elsevier eBooks
  22. Modulating the Activity of the VMPFC With tDCS Alters the Social Framing Effect
    Yuyou Chen, Xinbo Lu, Ping Yu, Lulu Zeng, Hang Ye, Qing Shi, Wenmin Guo · 2021 · Frontiers in Behavioral Neuroscience
  23. Adolescent social isolation disrupts developmental tuning of neuropeptide circuits in the hypothalamus to amygdala regulating social and defensive behavior
    Hiroyuki Arakawa, Mana Tokashiki, Yuki Higuchi, Toshihiro Konno · 2024 · Peptides
  24. Sex differences in the enjoyment of enrichment: affective bias testing confirms female rats prefer more playful and less vigorous tickling
    Catalina Gonzalez, A B Lawrence, Michael Mendl, Emma Robinson, Vincent Bombail, Sarah M. Brown · 2026 · Biology Letters
  25. Unilateral lesions of the dorsocentral striatum (DCS) disrupt spatial and temporal characteristics of food protection behavior
    Philip A. Blankenship, Joseph L. Cheatwood, Douglas G. Wallace · 2017 · Brain Structure and Function
  26. Sex Differences in Neuroanatomy and Neurophysiology
    Gretchen N. Neigh, Liana Merrill · 2016 · Elsevier eBooks
  27. Social play is critical for the development of prefrontal inhibitory synapses and cognitive flexibility in rats
    Ate Bijlsma, Azar Omrani, Marcia Spoelder, Jeroen P. H. Verharen, Lisa Bauer, Cosette Cornelis, Beleke de Zwart, René van Dorland, Louk J. M. J. Vanderschuren, Corette J. Wierenga · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Neurophysiological analysis of disadvantageous social inequity: Exploring emotional behavior changes and c-Fos expression in a male rat model
    Yujeong Jeong, Jihyun Noh · 2024 · Behavioural Brain Research
  29. Pharmacological Inhibition of the Nucleus Accumbens Increases Dyadic Social Interaction in Macaques
    Hannah F. Waguespack, Jessica T. Jacobs, Janis Park, Carolina Campos-Rodríguez, Rafael Souto Maior, Patrick Alexander Forcelli, Ludiše Málková · 2024 · eNeuro
  30. The role of play-derived experiences on the development of the medial prefrontal cortex and adult social behavior
    Rachel Stark · 2021
  31. Sex-specific vulnerability to single prolonged stress: behavioral alterations and redox imbalance in the developing brain
    Benedetta Di Cesare, Giulia Federica Mancini, Jacopo Maria Lisiola, Arianna Pisaneschi, Vladyslav Sikora, Maria Morena, Filippo Caraci, Marco Andrea Riva, Stefania Schiavone, Patrizia Campolongo · 2025 · Biochemical Pharmacology
  32. Aging of reward dopamine tracts in the human brain: A diffusion tensor imaging study
    Jeong Pyo Seo, Heun-Jae Ryu · 2023 · Medicine
  33. Pavlovian conditioning of social exploration in adult female rats
    Ceyhun Sunsay · 2018 · Behavioural Processes
  34. Aging of the mesolimbic tract in the human brain: A diffusion tensor imaging study
    Jeong Pyo Seo, Heun-Jae Ryu · 2022 · Medicine
  35. Exploring the brain-behaviour interface: The role of juvenile play experiences
    Brett T. Himmler · 2015 · Open ULeth Scholarship (OPUS) (University of Lethbridge)
  36. Are you serious? Relaxed open mouth may unveil the competitive/cooperative nature of play fighting in two feline species
    Elisa Demuru, Edoardo Collarini, Arianna Menon, Gioia Cesarano, Jérôme Catinaud, Ivan Norscia, Giada Cordoni · 2024 · Animal Behaviour
  37. Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling in the nucleus accumbens
    Susan Bowden, Kira D. Becker, Anna Luxhoj, Valery Grinevich, Jessica D.A. Lee, Alexa H. Veenema · 2026 · Hormones and Behavior
  38. The role of the dopamine D1 receptor in anticipatory pleasure and social play
    Kate M. Witt, David N. Harper, Bart A. Ellenbroek · 2024 · Neuropharmacology
  39. Efectos de la desnutrición perinatal en el desarrollo del juego juvenil de ratas
    Manuel Salas, Mirelta Regalado, Carmen Torrero · 2023 · eNeurobiología
  40. The brain at play: neural substrates of social play behaviour in adolescent rats
    Linda W. M. van Kerkhof · 2013 · Utrecht University Repository (Utrecht University)
  41. Social Play Behavior
    Louk J. M. J. Vanderschuren, E. J. Marijke Achterberg · 2020 · Elsevier eBooks
  42. Unravelling the Role of the Dopamine D1 Receptor in Anhedonia, Asociality, and Avolition
    Katherine Witt · 2023
  43. Rat Anterior Insula Symmetrically Represents Tickling-Induced Playful Emotions
    Sarah Dagher, Shimpei Ishiyama · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Low-Dose Stimulant Treatment During Periadolescence in a FASD Model: Interactions Among the Catecholamines
    Victoria Alice Macht · 2015 · Scholar Commons (University of South Carolina)
  45. Gestational day 12 moderate prenatal alcohol exposure produces sex-specific social impairments and attenuates prelimbic excitability and amygdala-cortex modulation of adult social behavior
    Kathryn R. Przybysz, Mary B. Spodnick, Julia M. Johnson, Elena I. Varlinskaya, Marvin Rafael Diaz · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  46. Neurophysiological and Social Development During Childhood
    Thomas A. Field, Michelle R. Ghoston · 2025
  47. Counseling Approaches II: Play Therapy and the Creative Arts
    Thomas A. Field, Michelle R. Ghoston · 2025
  48. Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections
    Yosuke Nishihata, Hiroki Yoshino, Yoichi Ogawa, Taketoshi Sugimura, Kazuya Okamura, Sohei Kimoto, Kazuhiko Yamamuro, Manabu Makinodan, Yasuhiko Saito, Taishiro Kishimoto · 2025 · Frontiers in Cellular Neuroscience
  49. The nucleus accumbens to ventral pallidum pathway regulates social play behavior via sex-specific mechanisms in juvenile rats
    J. Lee, Daniela Anderson, Isabella C. Orsucci, Susan Bowden, Alexa H. Veenema · 2026 · Brain Structure and Function
  50. Maternal exposure to witnessed social defeat stress induces sex-specific disruptions in juvenile social play behavior
    Andrew Justin Taylor, Robinson Carrasco-Gutiérrez, Arabia Olea-Araya, Pablo R. Moya, Alexies Dagnino‐Subiabre · 2025 · SSRN Electronic Journal
  51. Gestational environmental enrichment modulates neurophysiological and behavioral outcomes in adolescent rats after early-life stress: Sex differences in emotional and social behavior
    Ana Paula Toselli, Franco Baretta, Agustina Villegas, Oriana Micaela Casado, Franco Rafael Mir, María Angélica Rivarola · 2025 · Psychoneuroendocrinology
  52. Methylation and merriment: an exploration of epigenetic mechanisms underlying play behaviour
    Robert J. Malka, Marcos Arranz, Ignacio Baselga-Carretero · 2026 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
  53. Dysfonctionnements préfrontaux et pharmacothérapies dans des modèles murins de maladies spychiatriques
    Lamine Bouamrane · 2015 · theses.fr (ABES)
  54. Déficits synaptiques et comportementaux des voies méso-cortico-limbiques induits par le cannabis ou un déséquilibre alimentaire en acides gras polyinsaturés
    Anissa Bara · 2017
  55. Rôles différentiels du cortex cingulaire antérieur sous-génual et de l'insula antérieure dans la régulation des conséquences socio-affectives de l'exclusion sociale chez le rat
    Anna Fall · 2019 · theses.fr (ABES)
  56. Impacts d’une perturbation de la voie TSC2/mTOR dans l’amygdale dès l’adolescence sur le comportement de peur et la fonctionnalité du cortex préfrontal chez le rat adulte
    Fanny Joly · 2021 · theses.fr (ABES)
  57. Dimorphisme sexuel des trajectoires développementales de la plasticité synaptique endocannabinoïde dans le cortex préfrontal du rat
    Axel Bernabeu · 2020
  58. Reelin in vulnerability and sex-dependent maturational trajectories of the prefrontal cortex
    Thenzing J. Silva-Hurtado · 2021 · theses.fr (ABES)
  59. Effets d'un régime obésogène à l'adolescence sur les fonctions mnésiques et sociales dépendantes de la zone CA2 de l'hippocampe
    Alice Fermigier · 2024
  60. Safety and efficacy of AST-001 in children with autism spectrum disorder: a 52-week multicenter long-term follow-up study
    Johanna Inhyang Kim, Hyo‐Won Kim, Ji-Hoon Kim, MoonSoo Lee, Su‐Kyeong Hwang, Yoo‐Sook Joung · 2026 · Frontiers in Psychiatry
  61. Social environment enrichment enhances prosocial behavior in male mice via the oxytocin signaling and neuronal plasticity
    Changxin Li, Shunping Cui, Yao Yang, Jiahuan Lei, Y W Li, Ronghua Guo, Yang Yang, Yaoyao Tian, Jing Han, Fadao Tai et al. · 2026 · Current Zoology
  62. The effects of adolescent social isolation and group housing on adolescent binge drinking in mice
    Jyoti Lodha, Alanna Morgan, Rithika Balguri, Vera Purcell, Jennifer T. Wolstenholme · 2026 · PLoS ONE
  63. Maternal Exposure to Witnessed Social Defeat Stress Induces Sex‐Specific Disruptions in Juvenile Social Play Behavior in Rats
    Andrew Justin Taylor, Robinson Carrasco-Gutiérrez, Arabia Olea-Araya, Pablo R. Moya, Alexies Dagnino‐Subiabre · 2026 · Developmental Psychobiology