Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis

Nielsen, Suzanne, Sabioni, Pamela, Trigo, Jose M, Ware, Mark A, Betz-Stablein, Brigid D, Murnion, Bridin, Lintzeris, Nicholas, Khor, Kok Eng +3 more·2017·Neuropsychopharmacology

Cited by (265)

Items 101–200 of 265

  1. A Survey on the Effect That Medical Cannabis Has on Prescription Opioid Medication Usage for the Treatment of Chronic Pain at Three Medical Cannabis Practice Sites
    Kevin M. Takakuwa, Dustin Sulak · 2020 · Cureus
  2. A Scoping Review of the Use of Cannabis and Its Extracts as Potential Harm Reduction Strategies: Insights from Preclinical and Clinical Research
    James Siklos-Whillans, Alia Bacchus, Laurie A. Manwell · 2020 · International Journal of Mental Health and Addiction
  3. Cannabis use, pain interference, and prescription opioid receipt among persons with HIV: a target trial emulation study
    William C. Becker, Yu Li, Ellen C. Caniglia, Rachel Vickers‐Smith, Termeh Feinberg, Brandon D. L. Marshall, Eva Jennifer Edelman · 2021 · AIDS Care
  4. The cannabinoid agonist CB-13 produces peripherally mediated analgesia in mice but elicits tolerance and signs of central nervous system activity with repeated dosing
    Richard A. Slivicki, Jiwon Yi, Victoria E. Brings, Phuong Nhu Huynh, Robert W. Gereau · 2021 · Pain
  5. Medical Cannabis Use Reduces Opioid Prescriptions in Patients With Chronic Back Pain
    Ari C. Greis, Bryan Renslo, Adrianne R. Wilson‐Poe, Conan Liu, Anjithaa Radakrishnan, Asif M. Ilyas · 2022 · Cureus
  6. Legal Status of Recreational Cannabis and Self-Reported Substitution of Cannabis for Opioids or Prescription Pain Medication in Canada and the United States
    Elle Wadsworth, Lindsey A. Hines, David G. Hammond · 2022 · Substance Abuse
  7. Evaluating the co-use of opioids and cannabis for pain among current users using hypothetical purchase tasks
    Cecilia L. Bergeria, Sean B. Dolan, Matthew W. Johnson, Claudia M. Campbell, Kelly E. Dunn · 2020 · Journal of Psychopharmacology
  8. The Role of Cannabis, Cannabidiol and Other Cannabinoids in Chronic Pain. The Perspective of Physicians
    Markus Köstenberger, Gerhard Nahler, Trevor Jones, Stefan Neuwersch-Sommeregger, Rudolf Likar · 2021 · Journal of Neuroimmune Pharmacology
  9. Within-subject, double-blind, randomized, placebo-controlled evaluation of combining the cannabinoid dronabinol and the opioid hydromorphone in adults with chronic pain
    Claudia M. Campbell, Chung Jung Mun, Katrina R. Hamilton, Cecilia L. Bergeria, Andrew S. Huhn, Traci J. Speed, Ryan G. Vandrey, Kelly E. Dunn · 2023 · Neuropsychopharmacology
  10. Cannabinoide in der Schmerzmedizin
    Matthias Karst · 2018 · Der Schmerz
  11. Should oncologists trust cannabinoids?
    Ioana Creangă-Murariu, Leontina-Elena Filipiuc, Magdalena D. Cuciureanu, Bogdan-Ionel Tamba, Teodora Alexa‐Stratulat · 2023 · Frontiers in Pharmacology
  12. Cannabis‐based medicines and medical cannabis for patients with neuropathic pain and other pain disorders: Nationwide register‐based pharmacoepidemiologic comparison with propensity score matched controls
    Carsten Rygaard Hjorthøj, Peter la Cour, Merete Nordentoft, Christine Merrild Posselt · 2021 · European Journal of Pain
  13. Alternative pain management via endocannabinoids in the time of the opioid epidemic: Peripheral neuromodulation and pharmacological interventions
    Ming Tatt Lee, Ken Mackie, Lih‐Chu Chiou · 2021 · British Journal of Pharmacology
  14. Median Nerve Stimulation as a Nonpharmacological Approach to Bypass Analgesic Tolerance to Morphine: A Proof-of-Concept Study in Mice
    Ming Tatt Lee, Yi‐Hung Chen, Ken Mackie, Lih‐Chu Chiou · 2020 · Journal of Pain
  15. Overview: Chronic Pain and Cannabis-Based Medicines
    Matthias Karst · 2024 · Pharmacopsychiatry
  16. Cannabinoide reduzieren den Opioidverbrauch bei älteren Schmerzpatienten
    Knud Gastmeier, Anne Gastmeier, F. Rottmann, Thomas Herdegen, Rebekka A. Böhm · 2022 · Der Schmerz
  17. Postoperative Opioid Use Among Opioid-Naive Cannabis Users Following Single-Level Lumbar Fusions
    Syed Ibad Khalid, Sam Han Jiang, Harsh Khilwani, Kyle B. Thomson, Pranav Mirpuri, Ankit Indravadan Mehta · 2023 · World Neurosurgery
  18. Cannabis Use among Cancer Survivors: Use Pattern, Product Type, and Timing of Use
    Ikponmwosa Osaghae, Onyema Greg Chido‐Amajuoyi, Banda A. A. Khalifa, Rajesh Talluri, Sanjay S. Shete · 2023 · Cancers
  19. A Comprehensive Patient and Public Involvement Program Evaluating Perception of Cannabis-Derived Medicinal Products in the Treatment of Acute Postoperative Pain, Nausea, and Vomiting Using a Qualitative Thematic Framework
    Simon Erridge, Marie Miller, Tamara Gall, Antonio Costanzo, Barbara Pacchetti, Mikael Hans Sodergren · 2019 · Cannabis and Cannabinoid Research
  20. Waiting for the Entourage
    Daniele Piomelli · 2019 · Cannabis and Cannabinoid Research
  21. Medical Cannabis in Hand Surgery: A Review of the Current Evidence
    Andrew Yang, Clay B. Townsend, Asif M. Ilyas · 2023 · The Journal Of Hand Surgery
  22. Why a distinct medical stream is necessary to support patients using cannabis for medical purposes
    Cecilia Theresa Costiniuk, Caroline A. MacCallum, Michael R. Boivin, Sergio Rueda, Gary Lacasse, Zach Walsh, Paul Joseph Daeninck, Shari L. Margolese, Enrico Mandarino, Jagpaul Kaur Deol et al. · 2023 · Journal of Cannabis Research
  23. Cannabinoid Therapy in Athletics: A Review of Current Cannabis Research to Evaluate Potential Real-World Cannabinoid Applications in Sport
    Elizabeth S. Thompson, Jane Alcorn, J. Patrick Neary · 2024 · Sports Medicine
  24. Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological Interactions
    Marco Echeverria-Villalobos, Catherine A. Fabian, Justin Mitchell, Elvio Mazzota, Juan Fiorda‐Diaz, Kristen Noon, Tristan E. Weaver · 2024 · Anesthesia & Analgesia
  25. Opioid and healthcare service use in medical cannabis patients with chronic pain: a prospective study
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  26. Museum-Based Education: A Novel Educational Approach for Hospice and Palliative Medicine Training Programs
    Ali John Zarrabi, Laura J. Morrison, Barbara Reville, Joshua M. Hauser, Paul L. DeSandre, Marsha Joselow, Jane deLima Thomas, Gordoń Wood · 2020 · Journal of Palliative Medicine
  27. Cannabis and the Opioid Crisis
    Daniele Piomelli, Susan R.B. Weiss, Graham Boyd, Rosalie Liccardo Pacula, Ziva D. Cooper · 2018 · Cannabis and Cannabinoid Research
  28. Self-reported cannabis use is not associated with greater opioid use in elective hand surgery patients
    Nathan L. Bowers, Kevin Anthony Hao, Sunny M. Trivedi, Ellen Satteson, Joseph J. King, Thomas W. Wright, Robert C. Matthias · 2022 · European Journal of Orthopaedic Surgery & Traumatology
  29. Differential effect of cannabis use on opioid agonist treatment outcomes: Exploratory analyses from the OPTIMA study
    Laurent Elkrief, Gabriel Bastien, Christina McAnulty, Hamzah Bakouni, François-Olivier Hébert, Maria Eugenia Socias, Bernard Le Foll, Ron Lim, Omar Ledjiar, Stéphanie Marsan et al. · 2023 · Journal of Substance Use and Addiction Treatment
  30. Association between history of cannabis use and outcomes after total hip or knee arthroplasty: a systematic review and meta-analysis
    Guangyao Yang, Feng Li, Qiuyuan Wang, Youwen Liu, Jiayi Guo, Yue Chen · 2024 · Frontiers in Public Health
  31. Effects of oxycodone and diazepam alone and in combination on operant nociception
    Michael Z. Leonard, Brian D. Kangas · 2020 · Behavioural Pharmacology
  32. Morphine improved stress-induced amnesia and anxiety through interacting with the ventral hippocampal endocannabinoid system in rats
    Sima Abbasi Habashi, Zahra Ghasemzadeh, Ameneh Rezayof · 2020 · Brain Research Bulletin
  33. The association between cannabis use and risk of non-medical pain reliever misuse onset among young adults in a legal cannabis context
    Isaac C. Rhew, Vi T. Le, Jason J. Ramirez, Charles B. Fleming, Jason R. Kilmer, Miranda L. M. Delawalla, Brittney A. Hultgren, Christine M. Lee, Mary E. Larimer, Katarína Guttmannova · 2023 · Addictive Behaviors
  34. Developing non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidence
    Débora Silva de Oliveira, Rodrigo Fontenele, Jeremy Weleff, Mehmet Sofuoglu, João Paulo De Aquino · 2023 · International Review of Psychiatry
  35. Perioperative Multimodal Pain Management: an Evidence-Based Update
    David W. Creighton, Amanda H. Kumar, Stuart Alan Grant · 2019 · Current anesthesiology reports
  36. Risk Factors for Opioid Overdose
    Thokozeni Lipato, Mishka Terplan · 2018 · Current Treatment Options in Psychiatry
  37. Spezielle Schmerztherapie bei rheumatischen Erkrankungen
    Georg Pongratz · 2020 · Aktuelle Rheumatologie
  38. Treatment for Acute Pain: An Evidence Map
    Michelle Brasure, Victoria A. Nelson, Shellina Scheiner, Mary L Forte, Mary Butler, Sanket Nagarkar, Jayati Saha, Timothy J Wilt · 2019
  39. Pharmacological Strategies to Decrease Long-Term Prescription Opioid Use: A Systematic Review
    Hannah Ellerbroek, Gerard Arnoldus Kalkman, Cornelis Kramers, Arnt Schellekens, Bart J. F. van den Bemt · 2024 · Journal of Clinical Medicine
  40. Awareness and interest in cannabis use for cancer management among cancer survivors
    Ikponmwosa Osaghae, Rajesh Talluri, Onyema Greg Chido‐Amajuoyi, Kimberson Cochien Tanco, Dimpy P. Shah, Mala Pande, Sanjay S. Shete · 2024 · Cancer Medicine
  41. Effects of opioid/cannabinoid mixtures on impulsivity and memory in rhesus monkeys
    Vanessa Minervini, Charles Patrick France · 2020 · Behavioural Pharmacology
  42. Cannabis and its therapeutic value in the ageing population: Attitudes of health‐care providers
    Karan Chandiok, Shreeya Marathe, Miranda Rooney, Jess Stocker, Bianca Tellis, Sabrina Pit · 2021 · Australian Journal on Ageing
  43. Supporting gut health with medicinal cannabis in people with advanced cancer: potential benefits and challenges
    Hannah R. Wardill, Luke T. Wooley, Olivia M. Bellas, Katrina Cao, Courtney Cross, Madelé van Dyk, Ganessan Kichenadasse, Joanne M. Bowen, Andrew C.W. Zannettino, Sepehr Shakib et al. · 2023 · British Journal of Cancer
  44. Factors associated with health-related cannabis use intentions among a community sample of people who inject drugs in Los Angeles and San Francisco, CA 2016 to 2018
    Rachel Carmen Ceasar, Alex H. Kral, Kelsey A. Simpson, Lynn D. Wenger, Jesse L. Goldshear, Ricky N. Bluthenthal · 2020 · Drug and Alcohol Dependence
  45. Antinociceptive synergism upon the joint use of methadone and Phα1β in a model of cancer-related pain in C57BL/6J mice
    Luana Assis Ferreira, Caio Tavares Aoki, Duana Carvalho Santos, Marcio Junior Rezende, Mariana Peluci Garcia Mendes, Rodrigo Andrade Moura, Marina Ayres Delgado, Juliano Ferreira, Marcus V. Gomez, Célio José de Castro · 2021 · Life Sciences
  46. The Current Evidence for Marijuana as Medical Treatment
    Joseph Stewart Buck, Ainsley K. Bloomer, Meghan K. Wally, Rachel B. Seymour, Joseph R. Hsu · 2020 · Journal of Bone and Joint Surgery
  47. Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout mice
    Hannah Alton, Emily Linz, Guo‐Hua Bi, Omar Soler‐Cedeño, Maia Maras, Zheng‐Xiong Xi · 2025 · Neuropsychopharmacology
  48. Exploring the Relationship Between Substance Use and Allostatic Load in a Treatment/Research Cohort and in a US Probability Sample (NHANES 2009–2016)
    Jeffrey M. Rogers, David H. Epstein, Karran A. Phillips, Justin C. Strickland, Kenzie L. Preston · 2021 · Frontiers in Psychiatry
  49. Effect of cannabis use history on postoperative opioid utilization in lumbar fusion patients: an American retrospective study
    Pranav Mirpuri, Syed Ibad Khalid, Patrick King, Joanna Mary Roy, Aladine A. Elsamadicy, Ankit Indravadan Mehta, Owoicho Adogwa · 2024 · Asian Spine Journal
  50. Pharmacological Strategies for Suicide Prevention Based on the Social Pain Model: A Scoping Review
    Ravi Philip Rajkumar · 2022 · Psych
  51. Effect of Preoperative Marijuana on Patient Outcomes and Opioid Use after Lumbar Decompression
    Delano R. Trenchfield, Yunsoo A. Lee, Parker L. Brush, Michael T. McCurdy, Mark James Lambrechts, Rajkishen Narayanan, Alex Christianson, Azra Deez, Bright M. Wiafe, Ian David Kaye et al. · 2023 · Global Spine Journal
  52. Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain management
    David André Barrière, Élora Midavaine, Louis Doré-Savard, Karyn Kirby, Luc Tremblay, Jean-François Beaudoin, Nicolas Beaudet, Jean‐Michel Longpré, Roger Lecomte, Martin Lepage et al. · 2019 · Scientific Reports
  53. “ Less pain with more gain ”—Managing wound‐related pain with cannabis‐based medicines
    Vincent Maida, Stefano Armando Biasi · 2021 · Wound Repair and Regeneration
  54. Advances and prospects
    Vasantha K. Kumar · 2022 · Elsevier eBooks
  55. Tetrahydrocannabinol – friend or foe? – Debate
    Leslie Mendoza Temple, Jerrold Blair Leikin · 2019 · Clinical Toxicology
  56. CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid Receptors
    Laurie-Anne Roeckel, Dominique Massotte, Mary C. Olmstead, Katia Befort · 2018 · Frontiers in Psychiatry
  57. Cannabis medicinal na fibromialgia: um estudo de coorte para uma alternativa promissora
    Larissa Mendes da Silva, Linério Ribeiro de Novais Júnior, Vicente Meneguzzo, Tiago Vicente da Silva, Lara Rodrigues da Rosa, Tiago Odílio de Souza, Rafael Mariano de Bitencourt · 2023 · Revista Neurociências
  58. Letter to the Editor: Cannabis as a Solution to the Opioid Crisis: Is the Cart Before the Horse Again?
    João Paulo De Aquino, Anees Bahji, Deepak Cyril D’Souza · 2021 · Cannabis and Cannabinoid Research
  59. Craving for opioid and cannabis use among adults with chronic pain: Insights from a 30-day ecological momentary assessment study
    Jennifer D. Ellis, Ashley E Chipoletti, Siny Tsang, Courtney D. Nordeck, Erin M. Anderson Goodell, Chung Jung Mun, Marc Olivier Martel, Cecilia L. Bergeria, Kelly E. Dunn, Ryan G. Vandrey et al. · 2025 · Drug and Alcohol Dependence
  60. Practical Recommendations for the Use of Medical Cannabis
    Maria Fernanda Arboleda, Erin Prosk · 2021 · Springer eBooks
  61. A preliminary investigation of the acute effects of delta-9-tetrahydrocannabinol on pain and opioid attentional bias among persons with opioid use disorder
    Noah R. Wolkowicz, Mehmet Sofuoglu, Brian P. Pittman, Julia Meyerovich, Robert Ross MacLean, João Paulo De Aquino · 2024 · Journal of Psychiatric Research
  62. Cannabinoids
    Sulabha Sambhaji Lalsare · 2022 · Asian Journal of Pharmaceutical Research and Health Care
  63. Identification of Cannabigerol-Derived Dual CB2 Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities
    Wenjiao Yang, Haiguo Sun, Jing Ji, Hailan Chen, Jiaxin Cheng, Zhengtao Hu, Xudong Gong, Qi Liu, Su Peng, Jin Suo et al. · 2025 · Journal of Medicinal Chemistry
  64. The Role of Cannabidiol in Palliative Care #370
    April R. Christensen, Jennifer A. Pruskowski · 2019 · Journal of Palliative Medicine
  65. Daring discourse – yes: practical considerations for cannabis use in the perioperative setting
    Hance A. Clarke, Priodarshi Roychoudhury, Karim Shiraz Ladha, Timothy Sean Leroux, Joseph Fiorellino, Alexander Huang, Lakshmi P. Kotra · 2020 · Regional Anesthesia & Pain Medicine
  66. Cannabinoids and Pain
    Oliver Hulland, Jessica C. Oswald · 2021 · Rheumatic Disease Clinics of North America
  67. Cannabis Versus Opioids For Pain
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  68. Cannabis Use and Mental Health: Paradoxes of Medicalization
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  69. Community nurses' support for patients with fibromyalgia who use cannabis to manage pain
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    Leon Barron, Dani Gordon · 2019 · British Journal of General Practice
  71. The Efficacy and Safety of Use of Cannabis and Cannabinoid Products for Pain Relief in Orthopaedic Conditions and Trauma
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  74. Recreational cannabis dispensary access effects on prescription opioid use and mortality
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  75. THC Vapor Inhalation Attenuates Hyperalgesia in Rats Using a Chronic Inflammatory Pain Model
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  76. Cannabis use and illicit opioid cessation among people who use drugs living with chronic pain
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  78. Cannabinoids and Pain: Weeding Out Undesired Effects With a Novel Approach to Analgesia
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  79. Cannabinoids and Pain Management: an Insight into Recent Advancements
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  80. The Use of Marijuana Derivatives in Primary Care: An Evidence-Based Approach to Cannabidiol
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  81. Positive Toxicology Results Are Not Associated with Emergency Physicians’ Opioid Prescribing Behavior
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