Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis
Nielsen, Suzanne, Sabioni, Pamela, Trigo, Jose M, Ware, Mark A, Betz-Stablein, Brigid D, Murnion, Bridin, Lintzeris, Nicholas, Khor, Kok Eng +3 more·2017·Neuropsychopharmacology
Cited by (265)
Items 101–200 of 265
- A Survey on the Effect That Medical Cannabis Has on Prescription Opioid Medication Usage for the Treatment of Chronic Pain at Three Medical Cannabis Practice SitesKevin M. Takakuwa, Dustin Sulak · 2020 · Cureus
- A Scoping Review of the Use of Cannabis and Its Extracts as Potential Harm Reduction Strategies: Insights from Preclinical and Clinical ResearchJames Siklos-Whillans, Alia Bacchus, Laurie A. Manwell · 2020 · International Journal of Mental Health and Addiction
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- The cannabinoid agonist CB-13 produces peripherally mediated analgesia in mice but elicits tolerance and signs of central nervous system activity with repeated dosingRichard A. Slivicki, Jiwon Yi, Victoria E. Brings, Phuong Nhu Huynh, Robert W. Gereau · 2021 · Pain
- Medical Cannabis Use Reduces Opioid Prescriptions in Patients With Chronic Back PainAri C. Greis, Bryan Renslo, Adrianne R. Wilson‐Poe, Conan Liu, Anjithaa Radakrishnan, Asif M. Ilyas · 2022 · Cureus
- Legal Status of Recreational Cannabis and Self-Reported Substitution of Cannabis for Opioids or Prescription Pain Medication in Canada and the United StatesElle Wadsworth, Lindsey A. Hines, David G. Hammond · 2022 · Substance Abuse
- Evaluating the co-use of opioids and cannabis for pain among current users using hypothetical purchase tasksCecilia L. Bergeria, Sean B. Dolan, Matthew W. Johnson, Claudia M. Campbell, Kelly E. Dunn · 2020 · Journal of Psychopharmacology
- The Role of Cannabis, Cannabidiol and Other Cannabinoids in Chronic Pain. The Perspective of PhysiciansMarkus Köstenberger, Gerhard Nahler, Trevor Jones, Stefan Neuwersch-Sommeregger, Rudolf Likar · 2021 · Journal of Neuroimmune Pharmacology
- Within-subject, double-blind, randomized, placebo-controlled evaluation of combining the cannabinoid dronabinol and the opioid hydromorphone in adults with chronic painClaudia M. Campbell, Chung Jung Mun, Katrina R. Hamilton, Cecilia L. Bergeria, Andrew S. Huhn, Traci J. Speed, Ryan G. Vandrey, Kelly E. Dunn · 2023 · Neuropsychopharmacology
- Cannabinoide in der SchmerzmedizinMatthias Karst · 2018 · Der Schmerz
- Should oncologists trust cannabinoids?Ioana Creangă-Murariu, Leontina-Elena Filipiuc, Magdalena D. Cuciureanu, Bogdan-Ionel Tamba, Teodora Alexa‐Stratulat · 2023 · Frontiers in Pharmacology
- Cannabis‐based medicines and medical cannabis for patients with neuropathic pain and other pain disorders: Nationwide register‐based pharmacoepidemiologic comparison with propensity score matched controlsCarsten Rygaard Hjorthøj, Peter la Cour, Merete Nordentoft, Christine Merrild Posselt · 2021 · European Journal of Pain
- Alternative pain management via endocannabinoids in the time of the opioid epidemic: Peripheral neuromodulation and pharmacological interventionsMing Tatt Lee, Ken Mackie, Lih‐Chu Chiou · 2021 · British Journal of Pharmacology
- Median Nerve Stimulation as a Nonpharmacological Approach to Bypass Analgesic Tolerance to Morphine: A Proof-of-Concept Study in MiceMing Tatt Lee, Yi‐Hung Chen, Ken Mackie, Lih‐Chu Chiou · 2020 · Journal of Pain
- Overview: Chronic Pain and Cannabis-Based MedicinesMatthias Karst · 2024 · Pharmacopsychiatry
- Cannabinoide reduzieren den Opioidverbrauch bei älteren SchmerzpatientenKnud Gastmeier, Anne Gastmeier, F. Rottmann, Thomas Herdegen, Rebekka A. Böhm · 2022 · Der Schmerz
- Postoperative Opioid Use Among Opioid-Naive Cannabis Users Following Single-Level Lumbar FusionsSyed Ibad Khalid, Sam Han Jiang, Harsh Khilwani, Kyle B. Thomson, Pranav Mirpuri, Ankit Indravadan Mehta · 2023 · World Neurosurgery
- Cannabis Use among Cancer Survivors: Use Pattern, Product Type, and Timing of UseIkponmwosa Osaghae, Onyema Greg Chido‐Amajuoyi, Banda A. A. Khalifa, Rajesh Talluri, Sanjay S. Shete · 2023 · Cancers
- A Comprehensive Patient and Public Involvement Program Evaluating Perception of Cannabis-Derived Medicinal Products in the Treatment of Acute Postoperative Pain, Nausea, and Vomiting Using a Qualitative Thematic FrameworkSimon Erridge, Marie Miller, Tamara Gall, Antonio Costanzo, Barbara Pacchetti, Mikael Hans Sodergren · 2019 · Cannabis and Cannabinoid Research
- Waiting for the EntourageDaniele Piomelli · 2019 · Cannabis and Cannabinoid Research
- Medical Cannabis in Hand Surgery: A Review of the Current EvidenceAndrew Yang, Clay B. Townsend, Asif M. Ilyas · 2023 · The Journal Of Hand Surgery
- Why a distinct medical stream is necessary to support patients using cannabis for medical purposesCecilia Theresa Costiniuk, Caroline A. MacCallum, Michael R. Boivin, Sergio Rueda, Gary Lacasse, Zach Walsh, Paul Joseph Daeninck, Shari L. Margolese, Enrico Mandarino, Jagpaul Kaur Deol et al. · 2023 · Journal of Cannabis Research
- Cannabinoid Therapy in Athletics: A Review of Current Cannabis Research to Evaluate Potential Real-World Cannabinoid Applications in SportElizabeth S. Thompson, Jane Alcorn, J. Patrick Neary · 2024 · Sports Medicine
- Cannabinoids and General Anesthetics: Revisiting Molecular Mechanisms of Their Pharmacological InteractionsMarco Echeverria-Villalobos, Catherine A. Fabian, Justin Mitchell, Elvio Mazzota, Juan Fiorda‐Diaz, Kristen Noon, Tristan E. Weaver · 2024 · Anesthesia & Analgesia
- Opioid and healthcare service use in medical cannabis patients with chronic pain: a prospective studySharon R. Sznitman, Carolyn Mabouk, Zahi Said, Simon Vulfsons · 2021 · BMJ Supportive & Palliative Care
- Museum-Based Education: A Novel Educational Approach for Hospice and Palliative Medicine Training ProgramsAli John Zarrabi, Laura J. Morrison, Barbara Reville, Joshua M. Hauser, Paul L. DeSandre, Marsha Joselow, Jane deLima Thomas, Gordoń Wood · 2020 · Journal of Palliative Medicine
- Cannabis and the Opioid CrisisDaniele Piomelli, Susan R.B. Weiss, Graham Boyd, Rosalie Liccardo Pacula, Ziva D. Cooper · 2018 · Cannabis and Cannabinoid Research
- Self-reported cannabis use is not associated with greater opioid use in elective hand surgery patientsNathan L. Bowers, Kevin Anthony Hao, Sunny M. Trivedi, Ellen Satteson, Joseph J. King, Thomas W. Wright, Robert C. Matthias · 2022 · European Journal of Orthopaedic Surgery & Traumatology
- Differential effect of cannabis use on opioid agonist treatment outcomes: Exploratory analyses from the OPTIMA studyLaurent Elkrief, Gabriel Bastien, Christina McAnulty, Hamzah Bakouni, François-Olivier Hébert, Maria Eugenia Socias, Bernard Le Foll, Ron Lim, Omar Ledjiar, Stéphanie Marsan et al. · 2023 · Journal of Substance Use and Addiction Treatment
- Association between history of cannabis use and outcomes after total hip or knee arthroplasty: a systematic review and meta-analysisGuangyao Yang, Feng Li, Qiuyuan Wang, Youwen Liu, Jiayi Guo, Yue Chen · 2024 · Frontiers in Public Health
- Effects of oxycodone and diazepam alone and in combination on operant nociceptionMichael Z. Leonard, Brian D. Kangas · 2020 · Behavioural Pharmacology
- Morphine improved stress-induced amnesia and anxiety through interacting with the ventral hippocampal endocannabinoid system in ratsSima Abbasi Habashi, Zahra Ghasemzadeh, Ameneh Rezayof · 2020 · Brain Research Bulletin
- The association between cannabis use and risk of non-medical pain reliever misuse onset among young adults in a legal cannabis contextIsaac C. Rhew, Vi T. Le, Jason J. Ramirez, Charles B. Fleming, Jason R. Kilmer, Miranda L. M. Delawalla, Brittney A. Hultgren, Christine M. Lee, Mary E. Larimer, Katarína Guttmannova · 2023 · Addictive Behaviors
- Developing non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidenceDébora Silva de Oliveira, Rodrigo Fontenele, Jeremy Weleff, Mehmet Sofuoglu, João Paulo De Aquino · 2023 · International Review of Psychiatry
- Perioperative Multimodal Pain Management: an Evidence-Based UpdateDavid W. Creighton, Amanda H. Kumar, Stuart Alan Grant · 2019 · Current anesthesiology reports
- Risk Factors for Opioid OverdoseThokozeni Lipato, Mishka Terplan · 2018 · Current Treatment Options in Psychiatry
- Spezielle Schmerztherapie bei rheumatischen ErkrankungenGeorg Pongratz · 2020 · Aktuelle Rheumatologie
- Treatment for Acute Pain: An Evidence MapMichelle Brasure, Victoria A. Nelson, Shellina Scheiner, Mary L Forte, Mary Butler, Sanket Nagarkar, Jayati Saha, Timothy J Wilt · 2019
- Pharmacological Strategies to Decrease Long-Term Prescription Opioid Use: A Systematic ReviewHannah Ellerbroek, Gerard Arnoldus Kalkman, Cornelis Kramers, Arnt Schellekens, Bart J. F. van den Bemt · 2024 · Journal of Clinical Medicine
- Awareness and interest in cannabis use for cancer management among cancer survivorsIkponmwosa Osaghae, Rajesh Talluri, Onyema Greg Chido‐Amajuoyi, Kimberson Cochien Tanco, Dimpy P. Shah, Mala Pande, Sanjay S. Shete · 2024 · Cancer Medicine
- Effects of opioid/cannabinoid mixtures on impulsivity and memory in rhesus monkeysVanessa Minervini, Charles Patrick France · 2020 · Behavioural Pharmacology
- Cannabis and its therapeutic value in the ageing population: Attitudes of health‐care providersKaran Chandiok, Shreeya Marathe, Miranda Rooney, Jess Stocker, Bianca Tellis, Sabrina Pit · 2021 · Australian Journal on Ageing
- Supporting gut health with medicinal cannabis in people with advanced cancer: potential benefits and challengesHannah R. Wardill, Luke T. Wooley, Olivia M. Bellas, Katrina Cao, Courtney Cross, Madelé van Dyk, Ganessan Kichenadasse, Joanne M. Bowen, Andrew C.W. Zannettino, Sepehr Shakib et al. · 2023 · British Journal of Cancer
- Factors associated with health-related cannabis use intentions among a community sample of people who inject drugs in Los Angeles and San Francisco, CA 2016 to 2018Rachel Carmen Ceasar, Alex H. Kral, Kelsey A. Simpson, Lynn D. Wenger, Jesse L. Goldshear, Ricky N. Bluthenthal · 2020 · Drug and Alcohol Dependence
- Antinociceptive synergism upon the joint use of methadone and Phα1β in a model of cancer-related pain in C57BL/6J miceLuana Assis Ferreira, Caio Tavares Aoki, Duana Carvalho Santos, Marcio Junior Rezende, Mariana Peluci Garcia Mendes, Rodrigo Andrade Moura, Marina Ayres Delgado, Juliano Ferreira, Marcus V. Gomez, Célio José de Castro · 2021 · Life Sciences
- The Current Evidence for Marijuana as Medical TreatmentJoseph Stewart Buck, Ainsley K. Bloomer, Meghan K. Wally, Rachel B. Seymour, Joseph R. Hsu · 2020 · Journal of Bone and Joint Surgery
- Cannabinoid CB1 receptor and mu-opioid receptor interaction: new insights from conditional knockout miceHannah Alton, Emily Linz, Guo‐Hua Bi, Omar Soler‐Cedeño, Maia Maras, Zheng‐Xiong Xi · 2025 · Neuropsychopharmacology
- Exploring the Relationship Between Substance Use and Allostatic Load in a Treatment/Research Cohort and in a US Probability Sample (NHANES 2009–2016)Jeffrey M. Rogers, David H. Epstein, Karran A. Phillips, Justin C. Strickland, Kenzie L. Preston · 2021 · Frontiers in Psychiatry
- Effect of cannabis use history on postoperative opioid utilization in lumbar fusion patients: an American retrospective studyPranav Mirpuri, Syed Ibad Khalid, Patrick King, Joanna Mary Roy, Aladine A. Elsamadicy, Ankit Indravadan Mehta, Owoicho Adogwa · 2024 · Asian Spine Journal
- Pharmacological Strategies for Suicide Prevention Based on the Social Pain Model: A Scoping ReviewRavi Philip Rajkumar · 2022 · Psych
- Effect of Preoperative Marijuana on Patient Outcomes and Opioid Use after Lumbar DecompressionDelano R. Trenchfield, Yunsoo A. Lee, Parker L. Brush, Michael T. McCurdy, Mark James Lambrechts, Rajkishen Narayanan, Alex Christianson, Azra Deez, Bright M. Wiafe, Ian David Kaye et al. · 2023 · Global Spine Journal
- Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain managementDavid André Barrière, Élora Midavaine, Louis Doré-Savard, Karyn Kirby, Luc Tremblay, Jean-François Beaudoin, Nicolas Beaudet, Jean‐Michel Longpré, Roger Lecomte, Martin Lepage et al. · 2019 · Scientific Reports
- “ Less pain with more gain ”—Managing wound‐related pain with cannabis‐based medicinesVincent Maida, Stefano Armando Biasi · 2021 · Wound Repair and Regeneration
- Advances and prospectsVasantha K. Kumar · 2022 · Elsevier eBooks
- Tetrahydrocannabinol – friend or foe? – DebateLeslie Mendoza Temple, Jerrold Blair Leikin · 2019 · Clinical Toxicology
- CB1 Agonism Alters Addiction-Related Behaviors in Mice Lacking Mu or Delta Opioid ReceptorsLaurie-Anne Roeckel, Dominique Massotte, Mary C. Olmstead, Katia Befort · 2018 · Frontiers in Psychiatry
- Cannabis medicinal na fibromialgia: um estudo de coorte para uma alternativa promissoraLarissa Mendes da Silva, Linério Ribeiro de Novais Júnior, Vicente Meneguzzo, Tiago Vicente da Silva, Lara Rodrigues da Rosa, Tiago Odílio de Souza, Rafael Mariano de Bitencourt · 2023 · Revista Neurociências
- Letter to the Editor: Cannabis as a Solution to the Opioid Crisis: Is the Cart Before the Horse Again?João Paulo De Aquino, Anees Bahji, Deepak Cyril D’Souza · 2021 · Cannabis and Cannabinoid Research
- Craving for opioid and cannabis use among adults with chronic pain: Insights from a 30-day ecological momentary assessment studyJennifer D. Ellis, Ashley E Chipoletti, Siny Tsang, Courtney D. Nordeck, Erin M. Anderson Goodell, Chung Jung Mun, Marc Olivier Martel, Cecilia L. Bergeria, Kelly E. Dunn, Ryan G. Vandrey et al. · 2025 · Drug and Alcohol Dependence
- Practical Recommendations for the Use of Medical CannabisMaria Fernanda Arboleda, Erin Prosk · 2021 · Springer eBooks
- A preliminary investigation of the acute effects of delta-9-tetrahydrocannabinol on pain and opioid attentional bias among persons with opioid use disorderNoah R. Wolkowicz, Mehmet Sofuoglu, Brian P. Pittman, Julia Meyerovich, Robert Ross MacLean, João Paulo De Aquino · 2024 · Journal of Psychiatric Research
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- Identification of Cannabigerol-Derived Dual CB2 Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic ActivitiesWenjiao Yang, Haiguo Sun, Jing Ji, Hailan Chen, Jiaxin Cheng, Zhengtao Hu, Xudong Gong, Qi Liu, Su Peng, Jin Suo et al. · 2025 · Journal of Medicinal Chemistry
- The Role of Cannabidiol in Palliative Care #370April R. Christensen, Jennifer A. Pruskowski · 2019 · Journal of Palliative Medicine
- Daring discourse – yes: practical considerations for cannabis use in the perioperative settingHance A. Clarke, Priodarshi Roychoudhury, Karim Shiraz Ladha, Timothy Sean Leroux, Joseph Fiorellino, Alexander Huang, Lakshmi P. Kotra · 2020 · Regional Anesthesia & Pain Medicine
- Cannabinoids and PainOliver Hulland, Jessica C. Oswald · 2021 · Rheumatic Disease Clinics of North America
- Cannabis Versus Opioids For PainNoman Khalid, Abhishek Singh · 2021 · StatPearls
- Cannabis Use and Mental Health: Paradoxes of MedicalizationWilliam Dolphin, Michelle Newhart · 2022 · Springer eBooks
- Community nurses' support for patients with fibromyalgia who use cannabis to manage painNatasha J Andrews, Adele Phillips · 2021 · British Journal of Community Nursing
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- The role of cannabinoids in the management of symptoms in palliative care patientsMichał Graczyk, Wojciech Leppert · 2021 · Palliative Medicine in Practice
- Regulatory challenges on cannabisKumar Gautam Rohit, Pandey Ruchi, Dubey Itishree, Kushwaha Sapana · 2024 · Elsevier eBooks
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- THC Vapor Inhalation Attenuates Hyperalgesia in Rats Using a Chronic Inflammatory Pain ModelLeslie K. Kelley, Savannah H. M. Lightfoot, Matthew N. Hill, Jason W. Middleton, Nicholas W. Gilpin · 2024 · Journal of Pain
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- The Use of Marijuana Derivatives in Primary Care: An Evidence-Based Approach to CannabidiolCurtis Fowler · 2021 · The Journal for Nurse Practitioners
- Positive Toxicology Results Are Not Associated with Emergency Physicians’ Opioid Prescribing BehaviorJonathan B. Lee, Ghadi Ghanem, Soheil Saadat, Justin Yanuck, Brent Yeung, Bharath Chakravarthy, Ariana Marie Nelson, Shalini Shah · 2021 · Western Journal of Emergency Medicine
- Emergency Medicine Physicians Would Prefer Using Cannabis Over Opioids for First-Line Treatment of a Medical Condition if Provided With Medical Evidence: A National SurveyKevin M. Takakuwa, Raquel Marie Schears · 2021 · Cureus
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- Preoperative Cannabis Use Is Associated With Elevated Risk for Complications and Revision Surgery After Anterior Cervical Diskectomy and FusionSri Tummala, Tarun R. Sontam, Jason Noor, David C. Gibbs, James Rizkalla, Ioannis Avramis · 2025 · Journal of the American Academy of Orthopaedic Surgeons
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- UK Medical Cannabis Registry: an updated analysis of clinical outcomes of medicinal cannabis therapy for hypermobility-associated chronic painMariam Alemi, Simon Erridge, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad et al. · 2026 · Clinical Rheumatology
- Crossing the Line: Care of a Pediatric Patient with Intractable Seizures and Severe Neuropathic Pain in Absence of Access to Medical MarijuanaMeaghann Shaw Weaver, Adam R. White, Jacob E. Robinson · 2019 · Journal of Palliative Medicine
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- Associations Between Buprenorphine\Naloxone and Methadone Treatment and non-Opioid Substance Use in Prescription-Type Opioid Use Disorder: Secondary Analyses From the OPTIMA Study: Associations entre le traitement avec la buprénorphine/naloxone et avec la méthadone et l'utilisation de substances non opioïdes dans le trouble lié à l'usage d'opioïdes de type sur ordonnance : analyses secondaires de l'étude OPTIMAHamzah Bakouni, Heidar Sharafi, Sarah Drouin, Raphaëlle Fortin, Stéphanie Marsan, Suzanne Brissette, Maria Eugenia Socias, Bernard Le Foll, Ron Lim, Didier Jutras‐Aswad · 2023 · The Canadian Journal of Psychiatry
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