Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge
Sturm, Dominik, Bender, Sebastian, Jones, David T. W., Lichter, Peter, Grill, Jacques, Becher, Oren, Hawkins, Cynthia, Majewski, Jacek +7 more·2014·Nature Reviews Cancer
DOI 10.1038/nrc3655
Cites (230)
Items 201–230 of 230
- The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysmsHariyadarshi Pannu, Dong Kim, Dongchuan Guo, Terri M. King, Grace Van Ginhoven, Toinette Chin, Katherine Chang, Yuhua Qi, Sanjay S. Shete, Dianna M. Milewicz · 2006 · Journal of neurosurgery
- Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas.Katsumi Harada, Takafumi Nishizaki, S Ozaki, Hisashi Kubota, Haruhide Ito, Kohsuke Sasaki · 1998 · PubMed
- Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade gliomaJan Drappatz, Eudocia Q. Lee, S. Hammond, Sean Aaron Grimm, Andrew David Norden, Rameen Beroukhim, Mary Gerard, David Schiff, A. S., Tracy T. Batchelor et al. · 2011 · Journal of Neuro-Oncology
- Association of MutantTP53with Alternative Lengthening of Telomeres and Favorable Prognosis in GliomaYu-Jen Chen, Vicky Hakin-Smith, Mario Teo, George Xinarianos, David A. Jellinek, Thomas Carroll, David McDowell, Martin Richard MacFarlane, Ronald Boet, Bruce C. Baguley et al. · 2006 · Cancer Research
- Prognostic and predictive value of epigenetic silencing of MGMT in patients with high grade gliomas: a systematic review and meta-analysisRobert Olson, Priscilla Kaliopi Brastianos, David A. Palma · 2011 · Journal of Neuro-Oncology
- Gene Expression-Based Molecular Diagnostic System for Malignant Gliomas Is Superior to Histological DiagnosisMitsuaki Shirahata, Kyoko Iwao‐Koizumi, Sakae Saito, Noriko Ueno, Masashi Oda, Nobuo Hashimoto, Jun A. Takahashi, Kikuya Kato · 2007 · Clinical Cancer Research
- Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric GlioblastomaTakrima Haque, Damien Faury, Steffen Albrecht, Enrique López‐Aguilar, Péter Hauser, Miklós Garami, Zoltán Hanzély, László Bognár, Rolando F. Del Maestro, Jeffrey D. Atkinson et al. · 2007 · Clinical Cancer Research
- Intratumoral Patterns of Genomic Imbalance in GlioblastomasNobusawa, Sumihito, Lachuer, Joel, Wierinckx, Anne, Kim, Young Ho, Huang, Jian, Legras, Catherine, Kleihues, Paul, Ohgaki, Hiroko · 2010 · Brain Pathology
- Vertebrate animal models of glioma: Understanding the mechanisms and developing new therapiesLeon L. Chen, Yuqing Zhang, Jingxuan Yang, John P. Hagan, Min Li · 2013 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survivalSiyuan Zheng, Jun Fu, Rahulsimham Vegesna, Yong Mao, Lindsey E. Heathcock, Wandaliz Torres‐García, Ravesanker Ezhilarasan, Shuzhen Wang, Aaron McKenna, Lynda Chin et al. · 2013 · Genes & Development
- Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cellsHideto Koso, Haruna Takeda, Christopher Chin Kuan Yew, Jerrold Michael Ward, Naoki Nariai, Kazuko Ueno, Masao Nagasaki, Sumiko Watanabe, Alistair G. Rust, David J. Adams et al. · 2012 · Proceedings of the National Academy of Sciences
- Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed TherapiesJeonghee Cho, Sandra Pastorino, Qing Zeng, Xiaoyin Xu, William E Johnson, Scott R. VandenBerg, Roel G.W. Verhaak, Andrew D. Cherniack, Hideo Watanabe, Amit Dutt et al. · 2011 · Cancer Research
- IDH Mutations in Human GliomaWon Bae Kim, Linda M. Liau · 2012 · Neurosurgery Clinics of North America
- GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null backgroundSanna‐Maria Hede, Inga Hansson, Gijs Afink, Anna Eriksson, Inga Nazarenko, Johanna Andræ, Guillem Genové, Bengt Westermark, Monica Nistér · 2008 · Glia
- Inhibition of EGFR Induces a c-MET-Driven Stem Cell Population in GlioblastomaHyun Jung Jun, Roderick Terry Bronson, Alain Charest · 2013 · Stem Cells
- Telomerase activity and hTERT mRNA expression in glial tumorsLaura Boldrini, Sabina Pistolesi, Silvia Gisfredi, Silvia Ursino, Greta Alì, Nicola Pieracci, Fulvio Basolo, Giuliano Francesco Parenti, Gabriella Fontanini · 2006 · International Journal of Oncology
- A Mouse Model for Glioma: Biology, Pathology, and Therapeutic OpportunitiesEric C. Holland · 2000 · Toxicologic Pathology
- An Extensive Invasive Intracranial Human Glioblastoma Xenograft ModelYunge Zhao, Aizhen Xiao, Charles G. diPierro, Joan E. Carpenter, Rana Abdel‐Fattah, Gerard T. Redpath, Maria-Beatriz S. Lopes, Isa Marte Hussaini · 2010 · American Journal Of Pathology
- Clonal Analysis in Recurrent Astrocytic, Oligoastrocytic and Oligodendroglial Tumors Implicates IDH1- Mutation as Common Tumor Initiating EventUlrike Laß, Astrid Nümann, Kajetan von Eckardstein, J. C. W. Kiwit, Florian Stockhammer, Jorn A. Horaczek, Julian Veelken, Christel C. Herold‐Mende, Judith W. M. Jeuken, Andreas von Deimling et al. · 2012 · PLoS ONE
- RHPN2 Drives Mesenchymal Transformation in Malignant Glioma by Triggering RhoA ActivationCarla Danussi, Uri David Akavia, Francesco Niola, Andreja Jović, Anna Lasorella, Dana Pe’er, Antonio Iavarone · 2013 · Cancer Research
- Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFRα/βAleksandra B. Bielen, Lara Perryman, Gary Box, Melanie R. Valenti, Alexis de Haven Brandon, Vanessa Martins, Alexa Jury, Sergey Popov, Sharon M. Gowan, Sébastien Jeay et al. · 2011 · Molecular Cancer Therapeutics
- MGMT gene promoter methylation in pediatric glioblastomasArti Srivastava, Ayushi Jain, Prerana Jha, Vaishali S. Suri, Mehar Chand Sharma, Supriya Mallick, Tarun Puri, Deepak Kumar Gupta, Aditya Gupta, Chitra Sarkar · 2010 · Child s Nervous System
- Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels.S. Bozdag, Aiguo Li, Gregory Riddick, Y. Kotliarov, M. Baysan, F. Iwamoto, M. Cam, S. Kotliarova, H. Fine · 2013 · PLoS ONE
- MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPAJi Yeoun Lee, Chul‐Kee Park, Sung‐Hye Park, Kyu‐Chang Wang, Byung Kyu Cho, Seung‐Ki Kim · 2011 · Child s Nervous System
- Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomasFrancesca Romana Buttarelli, Maura Massimino, Manila Antonelli, Libero Lauriola, Paolo Nozza, Vittoria Donofrio, Antonietta Arcella, Maria Antonietta Oliva, Concezio Di Rocco, Felice Giangaspero · 2010 · Child s Nervous System
- Molecular Genetic Analysis of p53 Intratumoral Heterogeneity in Human Astrocytic Brain TumorsZhi-Ping Ren, Tommie Olofsson, Mingqi Qu, Göran Hesselager, Thierry Soussi, Hannu Kalimo, Anja Smits, Monica Nistér · 2007 · Journal of Neuropathology & Experimental Neurology
- Studying a Complex TumorSiyuan Zheng, Milan G. Chheda, Roel G.W. Verhaak · 2012 · The Cancer Journal
- Methylation-Related Chromatin Structure Is Associated with Exclusion of Transcription Factors from and Suppressed Expression of the O -6-Methylguanine DNA Methyltransferase Gene in Human Glioma Cell LinesJ Costello, Bernard W. Futscher, Roger A. Kroes, Russell O. Pieper · 1994 · Molecular and Cellular Biology
- Antagonistic modulation of gliomagenesis by Pax6 and Olig2 in PDGF‐induced oligodendrogliomaIrene Appolloni, Filippo Calzolari, Manuela Barilari, Marta Terrile, Antonio Daga, Paolo Malatesta · 2012 · International Journal of Cancer
- ML309: A potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cellsMindy I. Davis, Rajan Pragani, Janeta V. Popovici-Müller, Stefan Größ, Natasha Thorne, Frank Salituro, Valeria R. Fantin, Kimberly S. Straley, Michael S. S. Su, Lenny Dang et al. · 2013 · Europe PMC (PubMed Central)