Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

Sturm, Dominik, Bender, Sebastian, Jones, David T. W., Lichter, Peter, Grill, Jacques, Becher, Oren, Hawkins, Cynthia, Majewski, Jacek +7 more·2014·Nature Reviews Cancer

Cites (230)

Items 201–230 of 230

  1. The role of MMP-2 and MMP-9 polymorphisms in sporadic intracranial aneurysms
    Hariyadarshi Pannu, Dong Kim, Dongchuan Guo, Terri M. King, Grace Van Ginhoven, Toinette Chin, Katherine Chang, Yuhua Qi, Sanjay S. Shete, Dianna M. Milewicz · 2006 · Journal of neurosurgery
  2. Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas.
    Katsumi Harada, Takafumi Nishizaki, S Ozaki, Hisashi Kubota, Haruhide Ito, Kohsuke Sasaki · 1998 · PubMed
  3. Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma
    Jan Drappatz, Eudocia Q. Lee, S. Hammond, Sean Aaron Grimm, Andrew David Norden, Rameen Beroukhim, Mary Gerard, David Schiff, A. S., Tracy T. Batchelor et al. · 2011 · Journal of Neuro-Oncology
  4. Association of MutantTP53with Alternative Lengthening of Telomeres and Favorable Prognosis in Glioma
    Yu-Jen Chen, Vicky Hakin-Smith, Mario Teo, George Xinarianos, David A. Jellinek, Thomas Carroll, David McDowell, Martin Richard MacFarlane, Ronald Boet, Bruce C. Baguley et al. · 2006 · Cancer Research
  5. Prognostic and predictive value of epigenetic silencing of MGMT in patients with high grade gliomas: a systematic review and meta-analysis
    Robert Olson, Priscilla Kaliopi Brastianos, David A. Palma · 2011 · Journal of Neuro-Oncology
  6. Gene Expression-Based Molecular Diagnostic System for Malignant Gliomas Is Superior to Histological Diagnosis
    Mitsuaki Shirahata, Kyoko Iwao‐Koizumi, Sakae Saito, Noriko Ueno, Masashi Oda, Nobuo Hashimoto, Jun A. Takahashi, Kikuya Kato · 2007 · Clinical Cancer Research
  7. Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric Glioblastoma
    Takrima Haque, Damien Faury, Steffen Albrecht, Enrique López‐Aguilar, Péter Hauser, Miklós Garami, Zoltán Hanzély, László Bognár, Rolando F. Del Maestro, Jeffrey D. Atkinson et al. · 2007 · Clinical Cancer Research
  8. Intratumoral Patterns of Genomic Imbalance in Glioblastomas
    Nobusawa, Sumihito, Lachuer, Joel, Wierinckx, Anne, Kim, Young Ho, Huang, Jian, Legras, Catherine, Kleihues, Paul, Ohgaki, Hiroko · 2010 · Brain Pathology
  9. Vertebrate animal models of glioma: Understanding the mechanisms and developing new therapies
    Leon L. Chen, Yuqing Zhang, Jingxuan Yang, John P. Hagan, Min Li · 2013 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  10. A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival
    Siyuan Zheng, Jun Fu, Rahulsimham Vegesna, Yong Mao, Lindsey E. Heathcock, Wandaliz Torres‐García, Ravesanker Ezhilarasan, Shuzhen Wang, Aaron McKenna, Lynda Chin et al. · 2013 · Genes & Development
  11. Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells
    Hideto Koso, Haruna Takeda, Christopher Chin Kuan Yew, Jerrold Michael Ward, Naoki Nariai, Kazuko Ueno, Masao Nagasaki, Sumiko Watanabe, Alistair G. Rust, David J. Adams et al. · 2012 · Proceedings of the National Academy of Sciences
  12. Glioblastoma-Derived Epidermal Growth Factor Receptor Carboxyl-Terminal Deletion Mutants Are Transforming and Are Sensitive to EGFR-Directed Therapies
    Jeonghee Cho, Sandra Pastorino, Qing Zeng, Xiaoyin Xu, William E Johnson, Scott R. VandenBerg, Roel G.W. Verhaak, Andrew D. Cherniack, Hideo Watanabe, Amit Dutt et al. · 2011 · Cancer Research
  13. IDH Mutations in Human Glioma
    Won Bae Kim, Linda M. Liau · 2012 · Neurosurgery Clinics of North America
  14. GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background
    Sanna‐Maria Hede, Inga Hansson, Gijs Afink, Anna Eriksson, Inga Nazarenko, Johanna Andræ, Guillem Genové, Bengt Westermark, Monica Nistér · 2008 · Glia
  15. Inhibition of EGFR Induces a c-MET-Driven Stem Cell Population in Glioblastoma
    Hyun Jung Jun, Roderick Terry Bronson, Alain Charest · 2013 · Stem Cells
  16. Telomerase activity and hTERT mRNA expression in glial tumors
    Laura Boldrini, Sabina Pistolesi, Silvia Gisfredi, Silvia Ursino, Greta Alì, Nicola Pieracci, Fulvio Basolo, Giuliano Francesco Parenti, Gabriella Fontanini · 2006 · International Journal of Oncology
  17. A Mouse Model for Glioma: Biology, Pathology, and Therapeutic Opportunities
    Eric C. Holland · 2000 · Toxicologic Pathology
  18. An Extensive Invasive Intracranial Human Glioblastoma Xenograft Model
    Yunge Zhao, Aizhen Xiao, Charles G. diPierro, Joan E. Carpenter, Rana Abdel‐Fattah, Gerard T. Redpath, Maria-Beatriz S. Lopes, Isa Marte Hussaini · 2010 · American Journal Of Pathology
  19. Clonal Analysis in Recurrent Astrocytic, Oligoastrocytic and Oligodendroglial Tumors Implicates IDH1- Mutation as Common Tumor Initiating Event
    Ulrike Laß, Astrid Nümann, Kajetan von Eckardstein, J. C. W. Kiwit, Florian Stockhammer, Jorn A. Horaczek, Julian Veelken, Christel C. Herold‐Mende, Judith W. M. Jeuken, Andreas von Deimling et al. · 2012 · PLoS ONE
  20. RHPN2 Drives Mesenchymal Transformation in Malignant Glioma by Triggering RhoA Activation
    Carla Danussi, Uri David Akavia, Francesco Niola, Andreja Jović, Anna Lasorella, Dana Pe’er, Antonio Iavarone · 2013 · Cancer Research
  21. Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFRα/β
    Aleksandra B. Bielen, Lara Perryman, Gary Box, Melanie R. Valenti, Alexis de Haven Brandon, Vanessa Martins, Alexa Jury, Sergey Popov, Sharon M. Gowan, Sébastien Jeay et al. · 2011 · Molecular Cancer Therapeutics
  22. MGMT gene promoter methylation in pediatric glioblastomas
    Arti Srivastava, Ayushi Jain, Prerana Jha, Vaishali S. Suri, Mehar Chand Sharma, Supriya Mallick, Tarun Puri, Deepak Kumar Gupta, Aditya Gupta, Chitra Sarkar · 2010 · Child s Nervous System
  23. Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels.
    S. Bozdag, Aiguo Li, Gregory Riddick, Y. Kotliarov, M. Baysan, F. Iwamoto, M. Cam, S. Kotliarova, H. Fine · 2013 · PLoS ONE
  24. MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA
    Ji Yeoun Lee, Chul‐Kee Park, Sung‐Hye Park, Kyu‐Chang Wang, Byung Kyu Cho, Seung‐Ki Kim · 2011 · Child s Nervous System
  25. Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas
    Francesca Romana Buttarelli, Maura Massimino, Manila Antonelli, Libero Lauriola, Paolo Nozza, Vittoria Donofrio, Antonietta Arcella, Maria Antonietta Oliva, Concezio Di Rocco, Felice Giangaspero · 2010 · Child s Nervous System
  26. Molecular Genetic Analysis of p53 Intratumoral Heterogeneity in Human Astrocytic Brain Tumors
    Zhi-Ping Ren, Tommie Olofsson, Mingqi Qu, Göran Hesselager, Thierry Soussi, Hannu Kalimo, Anja Smits, Monica Nistér · 2007 · Journal of Neuropathology & Experimental Neurology
  27. Studying a Complex Tumor
    Siyuan Zheng, Milan G. Chheda, Roel G.W. Verhaak · 2012 · The Cancer Journal
  28. Methylation-Related Chromatin Structure Is Associated with Exclusion of Transcription Factors from and Suppressed Expression of the O -6-Methylguanine DNA Methyltransferase Gene in Human Glioma Cell Lines
    J Costello, Bernard W. Futscher, Roger A. Kroes, Russell O. Pieper · 1994 · Molecular and Cellular Biology
  29. Antagonistic modulation of gliomagenesis by Pax6 and Olig2 in PDGF‐induced oligodendroglioma
    Irene Appolloni, Filippo Calzolari, Manuela Barilari, Marta Terrile, Antonio Daga, Paolo Malatesta · 2012 · International Journal of Cancer
  30. ML309: A potent inhibitor of R132H mutant IDH1 capable of reducing 2-hydroxyglutarate production in U87 MG glioblastoma cells
    Mindy I. Davis, Rajan Pragani, Janeta V. Popovici-Müller, Stefan Größ, Natasha Thorne, Frank Salituro, Valeria R. Fantin, Kimberly S. Straley, Michael S. S. Su, Lenny Dang et al. · 2013 · Europe PMC (PubMed Central)