Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

Brunden, Kurt R., Trojanowski, John Q., Lee, Virginia M.-Y.·2009·Nature Reviews Drug Discovery
DOI 10.1038/nrd2959

Cited by (458)

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  12. Modélisation de l'interaction dynamique protéines Tau - microtubules
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  13. Modelling the neurobiology of Alzheimer’s disease in vitro
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  14. Molecular Marker and Therapeutic Regimen for Neurodegenerative Diseases
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  15. Characterization of Tau ELISAs for Evaluating Tau Accumulation in the Brains With Alzheimer’s Disease
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  16. Characterisation of Zampanolide as a Microtubule-Stabilizing Agent
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  19. PET Brain Imaging Methodologies
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  20. From Aggregation to Inhibition: N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding
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  21. Tubulin Modifying Enzymes as Target for the Treatment of Alzheimer's Disease: Old Perspective With A New Angle
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  23. Nanobodies directed against TAU as molecular tools to investigate immunotherapy in Alzheimer’s disease and related disorders
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  25. Exploring the Potential Interaction between the Functional Prion Protein CPEB3 and the Amyloidogenic Pathogenic Protein Tau
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  26. 7 Concussion: Long-term Sequelae Concussion
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  27. Nouveaux concepts pour une imagerie fonctionnelle des récepteurs sérotoninergiques 5-HT1A et 5-HT6 lors de processus neurodégénératifs
    Guillaume Becker · 2013 · theses.fr (ABES)
  28. Detection of the Alzheimer's disease soluble amyloid precursor protein and modulation of its proteolytic processing
    Taverna, Mara · 2014 · Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)
  29. REGULATION OF LOW DENSITY LIPOPROTEIN RECEPTOR SPLICING EFFICIENCY
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  30. Investigating the MAPT haplotype as a risk factor for neurodegenerative diseases with induced pluripotent stem cells
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  31. A novel role for free tubulin oligomers in cross-linking tau-mediated microtubule bundles: A structural study on protein assembly states
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  32. Tau nucléaire : un acteur clé dans le stress neuronal
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  33. Studies on the Role of Cellular Heparan Sulfate on Tau Pathology in Alzheimer's Disease and Related Tauopathies
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  39. Identification de nouveaux inhibiteurs de l’agrégation de la protéine Tau
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  41. Impact of α-synuclein fibrillar strains and ß-amyloid assemblies on cultured mouse cortical neurons endo-lysosomal logistics
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  42. Modulation des peptides amyloïde-β par des chélates azotés pour la thérapie de la maladie d’Alzheimer
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  43. Design and synthesis of trisubstituted 1,2,4-triazoles : structural exploration in the inhibition of GSK-3β for the treatment of Alzheimer’s disease
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  44. Small Molecules as Anti-Alzheimer’s Scaffolds
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  48. Synthetic Protein Mimetic Modulators of Tau Aggregation
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  49. BindingDB Entry 50015580: Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?
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  57. Innate Immunity in Alzheimer's disease
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  58. ANÁLISE CITOGENÉTICA COMO BIOINDICADOR PARA PACIENTES COM DIAGNÓSTICO SUGESTIVO DE ALZHEIMER
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