Mechanisms of trinucleotide repeat instability during human development

McMurray, Cynthia T.·2010·Nature Reviews Genetics

DOI 10.1038/nrg2828

Cited by (485)

Items 201–300 of 485

Oligodeoxynucleotide Binding to (CTG) · (CAG) Microsatellite Repeats Inhibits Replication Fork Stalling, Hairpin Formation, and Genome Instability
Guoqi Liu, Xiaomi Chen, Michael Leffak · 2012 · Molecular and Cellular Biology
Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans
Gabriel Cuéllar-Partida, Charles Laurin, Susan M. Ring, Tom R. Gaunt, Allan F. McRae, Peter M. Visscher, Grant W. Montgomery, Nicholas G. Martin, Gibran Hemani, Matthew J Suderman et al. · 2018 · Human Molecular Genetics
Genetic Instability and Chromatin Remodeling in Spermatids
Tiphanie Cavé, Rebecka Desmarais, Chloé Lacombe-Burgoyne, Guylain Boissonneault · 2019 · Genes
Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation
Roshan Satange, Chien-Ying Chuang, Stephen Neidle, Ming‐Hon Hou · 2019 · Nucleic Acids Research
Minidumbbell structures formed by ATTCT pentanucleotide repeats in spinocerebellar ataxia type 10
Pei Guo, Sik Lok Lam · 2020 · Nucleic Acids Research
AGG/CCT interruptions affect nucleosome formation and positioning of healthy-length CGG/CCG triplet repeats
Catherine B. Volle, Sarah Delaney · 2013 · BMC Biochemistry
Connections between 3′ end processing and DNA damage response: Ten years later
Michael Robert Murphy, Frida E. Kleiman · 2019 · Wiley Interdisciplinary Reviews - RNA
Partners in crime: Proteins implicated in RNA repeat expansion diseases
Anna Baud, Magdalena Derbis, Katarzyna Tutak, Krzysztof Sobczak · 2022 · Wiley Interdisciplinary Reviews - RNA
Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond
Essak S. Khan, Sven Danckwardt · 2022 · Genes
ERCC6L2 mitigates replication stress and promotes centromere stability
Christopher J. Carnie, Lucy V. Armstrong, Marek Šebesta, A. Ariza, Xiaomeng Wang, Emily B. Graham, Kang Zhu, Dragana Ahel · 2023 · Cell Reports
Establishing benchmarks and metrics for disruptive technologies, inappropriate and obsolete tests in the clinical laboratory
Frederick L. Kiechle, Rodney C. Arcenas, Linda C. Rogers · 2013 · Clinica Chimica Acta
Instability of Trinucleotidic Repeats During Chromatin Remodeling in Spermatids
Olivier Simard, Marie-Chantal Grégoire, Mélina Arguin, Marc-André Brazeau, Frédéric Leduc, Isabelle Marois, Martin V. Richter, Guylain Boissonneault · 2014 · Human Mutation
Huntington disease update: new insights into the role of repeat instability in disease pathogenesis
Larissa Arning, Huu Phuc Nguyen · 2021 · Medizinische Genetik
Chromatin changes in the development and pathology of the Fragile X-associated disorders and Friedreich ataxia
Daman Kumari, Rachel Adihe Lokanga, Dmitry V. Yudkin, Xiao-Nan Zhao, Karen Usdin · 2012 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Naphthyridine‐Benzoazaquinolone: Evaluation of a Tricyclic System for the Binding to (CAG)n Repeat DNA and RNA
Jinxing Li, Akihiro Sakata, Hanping He, Li‐Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani · 2016 · Chemistry - An Asian Journal
Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion
Gustavo A. Ruiz Buendía, Marion Leleu, Flavia Marzetta, Ludovica Vanzan, Jennifer Y. Tan, Victor Ythier, Emma L. Randall, Ana Claudia Marques, Tuncay Baubec, Rabih Murr et al. · 2020 · Science Advances
Nucleosome Positioning Regulates the Establishment, Stability, and Inheritance of Heterochromatin in Saccharomyces cerevisiae
Daniel S. Saxton, Jasper Rine · 2020 · Proceedings of the National Academy of Sciences
Expanded complexity of unstable repeat diseases
Urszula Polak, Elizabeth McIvor, Sharon Dent, Robert D. Wells, Марек Напиерала · 2012 · BioFactors
Increasing cotton genome coverage with polymorphic SSRs as revealed by SSCP
Ximei Li, Daojun Yuan, Hantao Wang, Xuemei Chen, Bin Wang, Zhongxu Lin, Xianlong Zhang · 2012 · Genome
Three‐dimensional genome structure and function
Hao Liu, Hsiangyu Tsai, Maoquan Yang, Guozhi Li, Qian Bian, Gang Ding, Dandan Wu, Jiewen Dai · 2023 · MedComm
Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism
Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Małgorzata Alabrudzińska, Adrianna Skoneczna, Piotr Jonczyk, Michał Dmowski, Iwona J. Fijałkowska · 2019 · PLoS Genetics
Factors associated with ATXN2 CAG/CAA repeat intergenerational instability in Spinocerebellar ataxia type 2
Luis Enrique Almaguer-Mederos, José Miguel Laffita Mesa, Yanetza González-Zaldívar, Dennis Almaguer‐Gotay, Dany Cuello‐Almarales, Raúl Aguilera‐Rodríguez, N Santos Falcón, Suzana Gispert, Georg W. J. Auburger, Luis Velázquez‐Pérez · 2018 · Clinical Genetics
Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease
Peter J. Giles, Lyn A. Elliston, Gemma V. Higgs, Simon P. Brooks, Stephen B. Dunnett, Lesley Jones · 2011 · Brain Research Bulletin
Large-scale expansions of Friedreich's ataxia GAA•TTC repeats in an experimental human system: role of DNA replication and prevention by LNA-DNA oligonucleotides and PNA oligomers
Anastasia Rastokina, Jorge Cebrián, Negin Mozafari, Nicholas H Mandel, C I Edvard Smith, Massimo Lopes, Rula Zain, Sergei M. Mirkin · 2023 · Nucleic Acids Research
Huntington disease-like 2: insight into neurodegeneration from an African disease
Amanda Krause, David G. Anderson, Aline Ferreira‐Correia, Jessica Dawson, Fiona Baine, Pan P. Li, Russell L. Margolis · 2023 · Nature Reviews Neurology
Modeling Human Trinucleotide Repeat Diseases in Drosophila
Zhenming Yu, Nancy M. Bonini · 2011 · International review of neurobiology
The Role of XPG in Processing (CAG)n/(CTG)n DNA Hairpins
Caixia Hou, Tianyi Zhang Zhang, Lei Tian, Jian Huang, Liya Gu, Guo‐Min Li · 2011 · Cell & Bioscience
DNA repair/replication transcripts are down regulated in patients with Fragile X Syndrome
Huichun Xu, Mónica Alejandra Rosales Reynoso, Patricio Barros‐Núñez, Emmanuel Kwame Peprah · 2013 · BMC Research Notes
Interstitial NORs, Fragile Sites, and Chromosome Evolution: A Not So Simple Relationship - The Example of Melolontha melolontha and Genus Protaetia (Coleoptera: Scarabaeidae)
Anne‐Marie Dutrillaux, Baptiste Carton, Lauriane Cacheux, Bernard Dutrillaux · 2016 · Cytogenetic and Genome Research
Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal
Jill M. Beaver, Yanhao Lai, Shantell J. Rolle, Yuan Liu · 2016 · DNA repair
A Novel Electrochemical Biosensor Based on a Double-Signal Technique for d(CAG)n Trinucleotide Repeats
Jiao Li, Yalan Liu, Xiaoqian Zhu, Gang Chang, Hanping He, Xun Zhang, Shengfu Wang · 2017 · ACS Applied Materials & Interfaces
Trinucleotide repeat instability via DNA base excision repair
Yanhao Lai, Jill M. Beaver, Eduardo E. Laverde, Yuan Liu · 2020 · DNA repair
Modelling and inference reveal nonlinear length-dependent suppression of somatic instability for small disease associated alleles in myotonic dystrophy type 1 and Huntington disease
Catherine F. Higham, Darren G. Monckton · 2013 · Journal of The Royal Society Interface
High incidence of microsatellite instability and loss of heterozygosity in three loci in breast cancer patients receiving chemotherapy: a prospective study
Nasir Kamat, Mohammed A. Khidhir, Mohammed Jaloudi, Sabir Hussain, Mouied Alashari, Khaled H. A. Al Qawasmeh, Ulf Rannug · 2012 · BMC Cancer
Unique Length-Dependent Biophysical Properties of Repetitive DNA
Ji Wei Huang, Sarah Delaney · 2016 · The Journal of Physical Chemistry B
A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich’s Ataxia
Ryan J. McGinty, Franco J. Puleo, Anna Yu. Aksenova, Julia A. Hisey, Alexander A. Shishkin, Erika L. Pearson, Eric T. Wang, David E. Housman, Claire L. Moore, Sergei M. Mirkin · 2017 · Cell Reports
An infrared spectral biomarker accurately predicts neurodegenerative disease class in the absence of overt symptoms
Lila Lovergne, Dhruba Ghosh, Renaud Schuck, Aris A. Polyzos, Andrew Chen, Michael C. Martin, Edward S. Barnard, James Brown, Cynthia T. McMurray · 2021 · Scientific Reports
Recurrent DNA nicks drive massive expansions of (GAA) n repeats
Liangzi Li, W. Shem Scott, Alexandra N. Khristich, Jillian F. Armenia, Sergei M. Mirkin · 2024 · Proceedings of the National Academy of Sciences
Trinucleotide repeat expansions catalyzed by human cell-free extracts
Jennifer R. Stevens, Elaine E Lahue, Guo‐Min Li, Robert S. Lahue · 2013 · Cell Research
Abnormal Base Excision Repair at Trinucleotide Repeats Associated with Diseases: A Tissue-Selective Mechanism
Agathi-Vasiliki Goula, Karine Mérienne · 2013 · Genes
Impact of bulge loop size on DNA triplet repeat domains: Implications for DNA repair and expansion
Jens Völker, Georg Plum, Vera S. Gindikin, Horst H. KLUMP, Kenneth J. Breslauer · 2013 · Biopolymers
Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?
Spandan Kalra, Federica Montanaro, Chris N. Denning · 2016 · Journal of Neuromuscular Diseases
Chemotherapy induced microsatellite instability and loss of heterozygosity in chromosomes 2, 5, 10, and 17 in solid tumor patients
Nasir Kamat, Mohammed A. Khidhir, Sabir Hussain, Mouied Alashari, Ulf Rannug · 2014 · Cancer Cell International
Novel eGZ-motif formed by regularly extruded guanine bases in a left-handed Z-DNA helix as a major motif behind CGG trinucleotide repeats
Ashkan Fakharzadeh, Jiahui Zhang, Christopher Roland, Celeste Sagui · 2022 · Nucleic Acids Research
G-Quadruplexes in Repeat Expansion Disorders
Ye Teng, Ming Liang Zhu, Zhidong Qiu · 2023 · International Journal of Molecular Sciences
Epigenetic modifications in human fragile X pluripotent stem cells; Implications in fragile X syndrome modeling
Jeannine Gerhardt · 2015 · Brain Research
DNA repair in trinucleotide repeat ataxias
Wai Yan Yau, Emer O’Connor, Roisin Sullivan, Layan Akijian, Nicholas William Wood · 2018 · FEBS Journal
Development of novel macrocyclic small molecules that target CTG trinucleotide repeats
Julio F. Serrano, JuYeon Lee, L. Daniel Curet, Lauren D. Hagler, Sarah B. Krueger, Emma J. Schuster, Steven C. Zimmerman · 2019 · Bioorganic & Medicinal Chemistry
Familial Aggregation in Idiopathic Subglottic Stenosis
Virginia E. Drake, Alexander H. Gelbard, Nara Lygia de Macena Sobreira, Elizabeth Wohler, Lynne D. Berry, Lena L. Hussain, Alexander T. Hillel · 2020 · Otolaryngology
Tandem repeat variation shapes immune cell type-specific gene expression
Hope A. Tanudisastro, Anna S. E. Cuomo, Ben Weisburd, Matthew J. Welland, Eleanor Spenceley, Michael Franklin, Angli Xue, Hao Lawrence Huang, Blake Bowen, Jianan Fan et al. · 2026 · Nature
The landcape of Helicobacter pylori-mediated DNA breaks links bacterial genotoxicity to its oncogenic potential
Hadas Sibony-Benyamini, Rose Jbara, Tania Shubash Napso, Layan Abu Rahmoun, Daniel Vizenblit, Michal Easton-Mor, Shira Perez, Alexander S. Brandis, Tamar Leshem, Avi Peretz et al. · 2025 · Genome Medicine
Modulating RNA secondary and tertiary structures by mismatch binding ligands
Asako Murata, Masayuki Nakamori, Kazuhiko Nakatani · 2019 · Methods
Disease Expression and Familial Transmission of Fuchs Endothelial Corneal Dystrophy With and Without CTG18.1 Expansion
Timothy T. Xu, Yi‐Ju Li, Natalie A. Afshari, Ross A. Aleff, Tommy A. Rinkoski, Sanjay V. Patel, Leo J. Maguire, Albert O. Edwards, William L. Brown, Michael P. Fautsch et al. · 2021 · Investigative Ophthalmology & Visual Science
A worldwide map of swine short tandem repeats and their associations with evolutionary and environmental adaptations
Zhongzi Wu, Huanfa Gong, Mingpeng Zhang, Xinkai Tong, Huashui Ai, Shijun Xiao, Miguel Pérez-enciso A, Bin Juan Yang, Lusheng Huang · 2021 · Genetics Selection Evolution
DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington’s disease via insertion sequences of its catalytic domain
Kara Y. Chan, Xueying Li, Janice Ortega, Liya Gu, Guo‐Min Li · 2021 · Journal of Biological Chemistry
Frustration Between Preferred States of Complementary Trinucleotide Repeat DNA Hairpins Anticorrelates with Expansion Disease Propensity
Pengning Xu, Jiahui Zhang, Feng Pan, Chelsea Mahn, Christopher Roland, Celeste Sagui, Keith Weninger · 2023 · Journal of Molecular Biology
Trinucleotide repeats and haplotypes at the Huntingtin locus in an Indian sample overlaps with European haplogroup A
Nagaraj S. Moily, Lakshmi Narayanan Kota, Ram Murthy Anjanappa, Sowmya Venugopal, Radhika Vaidyanathan, Pramod Kumar Pal, Meera Purushottam, Sanjeev Jain, Mahesh Kandasamy · 2014 · PLoS Currents
A Glutamine Repeat Variant of the RUNX2 Gene Causes Cleidocranial Dysplasia
Masaki Mastushita, Hiroshi Kitoh, Aslı Subaşıoğlu, Fatma Kurt Çolak, Munis Dündar, Kenichi Mishima, Yoshihiro Nishida, Naoki Ishiguro · 2015 · Molecular Syndromology
Alterations in the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology
Y.-M. Zheng, L. Li, Liming Zhou, Le Fang, Lingbo Cai, P. Yu, Yaping Zhu, X.-Z. Liu, L.-Y. Wang, L.-J. Li et al. · 2013 · Human Reproduction
Somatic intronic microsatellite loci differentiate glioblastoma from lower-grade gliomas
Enusha Karunasena, Lauren J. McIver, Brian R. Rood, Xiaowei Wu, Hongxiao Zhu, Jasmin H. Bavarva, Harold R. Garner · 2014 · Oncotarget
Sequence-Dependent Effects of Monovalent Cations on the Structural Dynamics of Trinucleotide-Repeat DNA Hairpins
Marisa L. Mitchell, Michael P. Leveille, Roman S. Solecki, T. Thao Tran, Brian L. Cannon · 2018 · The Journal of Physical Chemistry B
Structural and Dynamical Properties of Nucleic Acid Hairpins Implicated in Trinucleotide Repeat Expansion Diseases
Feng Pan, Pengning Xu, Christopher Roland, Celeste Sagui, Keith Weninger · 2024 · Biomolecules
Detection of Tandem Repeats in DNA Sequences Using Short-Time Ramanujan Fourier Transform
Yashpal Yadav, Sanjeev Narayan Sharma, Devendra Kumar Shakya · 2021 · IEEE Transactions on Computational Biology and Bioinformatics
New Perspectives of Gene Therapy on Polyglutamine Spinocerebellar Ataxias: From Molecular Targets to Novel Nanovectors
Fabiola V. Borbolla‐Jiménez, María Luisa Del Prado-Audelo, Bulmaro Cisneros, Isaac Hiram Caballero-Florán, Gerardo Leyva‐Gómez, Jonathan J. Magaña · 2021 · Pharmaceutics
Nucleotide excision repair and the 26S proteasome function together to promote trinucleotide repeat expansions
Claire Concannon, Robert S. Lahue · 2013 · DNA repair
Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR
Nimrat Chatterjee, Yunfu Lin, John H. Wilson · 2016 · DNA repair
Deep sequencing of mitochondrial genomes reveals increased mutation load in Friedreich's ataxia
Angela D. Bhalla, Alireza Khodadadi‐Jamayran, Yanjie Li, David R. Lynch, Марек Напиерала · 2016 · Annals of Clinical and Translational Neurology
The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches
Yu‐Wen Chen, Ming‐Hon Hou · 2012 · Journal of Inorganic Biochemistry
A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models
Susumu Ikenoshita, Kazuya Matsuo, Yasushi Yabuki, Kosuke Kawakubo, Sefan Asamitsu, Karin Hori, Shingo Usuki, Yuki Hirose, Toshikazu Bando, Kimi Araki et al. · 2023 · Journal of Clinical Investigation
A Dual-Mode Single-Molecule Fluorescence Assay for the Detection of Expanded CGG Repeats in Fragile X Syndrome
Brian L. Cannon, Cynthia Pan, Liangjing Chen, Andrew G. Hadd, Rick Russell · 2012 · Molecular Biotechnology
DNA mismatch repair in trinucleotide repeat instability
Jinzhen Guo, Luping Chen, Guo‐Min Li · 2017 · Science China Life Sciences
Methods to Study Repeat Fragility and Instability in Saccharomyces cerevisiae
Erica J. Polleys, Catherine H. Freudenreich · 2017 · Methods in molecular biology
Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6
Arumay Pal, Harry M. Greenblatt, Yaakov Levy · 2020 · Biochemistry
Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast genetics
Monika Aggarwal, Robert M. Brosh · 2012 · DNA repair
Defining Genetic Factors That Modulate Intergenerational CAG Repeat Instability inDrosophila melanogaster
Joonil Jung, Marijn T. M. van Jaarsveld, Shin-Yi Shieh, Kexiang Xu, Nancy M. Bonini · 2010 · Genetics
Characterizing tandem repeat complexities across long-read sequencing platforms with TREAT and otter
Niccoló Tesi, Alex Salazar, Yaran Zhang, Sven J. van der Lee, Marc Hulsman, Lydian Knoop, Sanduni Wijesekera, Jana Křížová, Anne-Fleur E. Schneider, Maartje Pennings et al. · 2024 · Genome Research
The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription inSaccharomyces cerevisiae
Melissa R. Koch, Nealia C. M. House, Casey M. Cosetta, Robyn M. Jong, Christelle G Salomon, Cailin E. Joyce, Elliot A. Philips, Xiaofeng A. Su, Catherine H. Freudenreich · 2018 · Genetics
Open chromatin structure in PolyQ disease-related genes: a potential mechanism for CAG repeat expansion in the normal human population
Matan Sorek, Lea R Z Cohen, Eran Meshorer · 2019 · NAR Genomics and Bioinformatics
Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
Rana Dilara Incebacak Eltemur, Huu Phuc Nguyen, Jonasz Jeremiasz Weber · 2022 · Frontiers in Molecular Neuroscience
Disease Diagnosis Using Pattern Matching Algorithm from DNA Sequencing
Sandeep U. Mane, Ketaki H. Pangu · 2016 · International Conference on Informatics and Analytics
Progressive Polyglutamine Repeat Expansion in Peripheral Blood Cells and Sperm of Transgenic Huntington’s Disease Monkeys
Faye Clever, In Ki Cho, Jingjing Yang, Anthony W.S. Chan · 2019 · Journal of Huntington s Disease
Dynamic DNA Energy Landscapes and Substrate Complexity in Triplet Repeat Expansion and DNA Repair
Jens Völker, Georg Plum, Vera S. Gindikin, Kenneth J. Breslauer · 2019 · Biomolecules
Nucleosomal occupancy and CGG repeat expansion: a comparative analysis of triplet repeat region from mouse and human fragile X mental retardation gene 1
Sonal Datta, Mohammad Parwez Alam, Subeer S. Majumdar, Abhishek Kumar Mehta, Souvik Maiti, Neerja Wadhwa, Vani Brahmachari · 2011 · Chromosome Research
Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo
Melisa Medina‐Rivera, Samantha E. Phelps, Madhumita Sridharan, Jordan T. Becker, Natalie A. Lamb, Charanya Kumar, Mark D. Sutton, Anja‐Katrin Bielinsky, Lata Balakrishnan, Jennifer A. Surtees · 2023 · Nucleic Acids Research
CAG repeat instability in embryonic stem cells and derivative spermatogenic cells of transgenic Huntington’s disease monkey
Sujittra Khampang, Rangsun Parnpai, Wiriya Mahikul, Charles A. Easley, In Ki Cho, Anthony W.S. Chan · 2021 · Journal of Assisted Reproduction and Genetics
Fanconi anemia pathway regulates convergent transcription-induced cell death at trinucleotide repeats in human cells
Nimrat Chatterjee, Yunfu Lin, John H. Wilson · 2016 · Postdoc Journal
Selective Forces Related to Spinocerebellar Ataxia Type 2
Lucas Schenatto Sena, Raphael Machado Castilhos, Eduardo Preusser de Mattos, Gabriel Vasata Furtado, José Luiz Pedroso, Orlando Graziani Póvoas Barsottini, Maria Marla Paiva de Amorim, Clecio de Oliveira Godeiro-Junior, Maria Luiza Saraiva Pereira, Laura Bannach Jardim · 2018 · The Cerebellum
Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease
Tianle Chen, Yuanjia Wang, Yanyuan Ma B, Karen S. Marder, Douglas R. Langbehn · 2012 · Journal of Probability and Statistics
Site-specific incorporation of multiple units of functional nucleotides into DNA using a step-wise approach with polymerase and its application to monitoring DNA structural changes
Binh Huy Le, Văn Thắng Nguyễn, Young Jun Seo · 2019 · Chemical Communications
Analysis of De Novo HOXA 13 Polyalanine Expansions Supports Replication Slippage Without Repair in Their Generation
Kailey M. Owens, Shane C. Quinonez, Peedikayil E. Thomas, Catherine E. Keegan, N D Smith Lefebvre, Diane Roulston, Christine A. Larsen, H. Scott Stadler, Jeffrey W. Innis · 2013 · American Journal of Medical Genetics Part A
Structural Dynamics Role of AGG Interruptions in Inhibition CGG Repeat Expansion Associated with Fragile X Syndrome
Yang-I Shen, Kai-Chun Cheng, Yu-Jie Wei, I‐Ren Lee · 2023 · ACS Chemical Neuroscience
Epimutations and mutations, nurturing phenotypic diversity
Jasmine M. Shah · 2021 · Genetica
Somatic and intergenerational G4C2 hexanucleotide repeat instability in a human C9orf72 knock-in mouse model
Nada Kojak, Junko Kuno, Kristina E Fittipaldi, Ambereen Khan, David Wenger, Michael Glasser, Roberto Antonio Donnianni, Yajun Tang, Jade Zhang, Katie Huling et al. · 2024 · Nucleic Acids Research
Ethidium Bromide Modifies The Agarose Electrophoretic Mobility of CAG•CTG Alternative DNA Structures Generated by PCR
Mário Gomes-Pereira, Darren G. Monckton · 2017 · Frontiers in Cellular Neuroscience
Instability of TCF4 Triplet Repeat Expansion With Parent–Child Transmission in Fuchs' Endothelial Corneal Dystrophy
Joanna S Saade, Chao Xing, Xin Gong, Zhengyang Zhou, V. Vinod Mootha · 2018 · Investigative Ophthalmology & Visual Science
Genome-wide survey of tandem repeats by nanopore sequencing shows that disease-associated repeats are more polymorphic in the general population
Satomi Mitsuhashi, Martin C. Frith, Naomichi Matsumoto · 2021 · BMC Medical Genomics
A flexible polyglutamine hinge opens new doors for understanding huntingtin function
Flaviano Giorgini · 2013 · Proceedings of the National Academy of Sciences
Drastic stability change of X-X mismatch in d(CXG) trinucleotide repeat disorders under molecular crowding condition
Ye Teng, Smritimoy Pramanik, Hisae Tateishi‐Karimata, Tatsuya Ohyama, Naoki Sugimoto · 2018 · Biochemical and Biophysical Research Communications
The curious incident of TdT-mediated mutations in AML
George S. Vassiliou · 2019 · Blood
Genetic Assays to Study Repeat Fragility in Saccharomyces cerevisiae
Erica J. Polleys, Catherine H. Freudenreich · 2019 · Methods in molecular biology