The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Next-generation sequencing in the clinic: are we ready?
Open accessAbstract
We are entering an era in which the cost of clinical whole-genome and targeted sequencing tests is no longer prohibitive to their application. However, currently the infrastructure is not in place to support both the patient and the physicians that encounter the resultant data. Here, we ask five experts to give their opinions on whether clinical data should be treated differently from other medical data, given the potential use of these tests, and on the areas that must be developed to improve patient outcome.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Tversky, A., & Kahneman, D. (1974) · Science · doi:10.1126/science.185.4157.1124 · Cited by 28,810
Cited by
O’Sullivan, J. W., Raghavan, S., Marquez-Luna, C., Luzum, J. A., Damrauer, S. M., Ashley, E. A., O’Donnell, C. J., Willer, C. J., Natarajan, P., & on behalf of the American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, T. A. V. B. C. O. C. R. A. I. C. O. L. A. C. H. A. C. O. P. V. D. (2022) · Circulation · doi:10.1161/cir.0000000000001077 · Cited by 412
Shashi, V., McConkie-Rosell, A., Rosell, B., Schoch, K., Vellore, K., McDonald, M., Jiang, Y.-H., Xie, P., Need, A., & Goldstein, D. B. (2014) · Genetics in Medicine · doi:10.1038/gim.2013.99 · Cited by 290
Advances in technologies for screening and diagnosis of hemoglobinopathies
Traeger-Synodinos, J., & Harteveld, C. L. (2014) · Biomarkers in Medicine · doi:10.2217/bmm.13.103 · Cited by 53
Metadata
- Authors
- Biesecker, L. G., Burke, W., Kohane, I., Plon, S. E., & Zimmern, R.
- Venue
- Nature Reviews Genetics
- Published
- 2012-10-18
- Volume
- 13
- Issue
- 11
- Pages
- 818-824
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2044455269
- Cited by
- 158
- References
- 1
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Next-generation sequencing in the clinic: are we ready? https://app.cochat.ai/papers/10.1038/nrg3357
- The paper
- Biesecker, L. G., Burke, W., Kohane, I., Plon, S. E., & Zimmern, R. (2012). Next-generation sequencing in the clinic: are we ready? Nature Reviews Genetics. https://doi.org/10.1038/nrg3357
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
