The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
The origin and evolution of model organisms
Abstract
The phylogeny and timescale of life are becoming better understood as the analysis of genomic data from model organisms continues to grow. As a result, discoveries are being made about the early history of life and the origin and development of complex multicellular life. This emerging comparative framework and the emphasis on historical patterns is helping to bridge barriers among organism-based research communities.
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“This value is much lower than most of the previously published ones (12, 17, 46) but is close to recent estimates (22, 23)”
From The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils? (2004) · cites this paper as [12]
In the citing paper
“Molecular estimates of divergence times are, however, controversial and are generally much more ancient than suggested by the fossil record.”
From The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils? (2004) · cites this paper as [12]
In the citing paper
“Our molecular time scale for the major eukaryotic clades is on average 1.5 times more recent than the one based on a global clock (12).”
From The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils? (2004) · cites this paper as [12]
In the citing paper
“Previous molecular datings yielded molecular ages always more ancient than paleontological ones, but often to a large extent (12, 15, 20, 46).”
From The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils? (2004) · cites this paper as [12]
In the citing paper
“The major eukaryotic kingdoms therefore originated much more recently than previously thought (12) but did not seem to have been affected by the postulated global glaciations (“snowball Earth” hypothesis) between 750 and 600 Mya (56).”
From The timing of eukaryotic evolution: Does a relaxed molecular clock reconcile proteins and fossils? (2004) · cites this paper as [12]
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Metadata
- Authors
- Hedges, S. B.
- Affiliations
- Pennsylvania State University (US)
- Corresponding author
- Hedges, S. Blair
- ORCID
- Hedges, S. Blair
- Venue
- Nature Reviews Genetics
- Published
- 2002-11
- Volume
- 3
- Issue
- 11
- Pages
- 838-849
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2118025286
- Semantic Scholar
- 862571824f8482780d0884d28274f54a62ec611f
- Cited by
- 806
- References
- 124
- Citations by year
- 2026: 10 · 2025: 17 · 2024: 22 · 2023: 27 · 2022: 27 · 2021: 21 · 2020: 18 · 2019: 19 · 2018: 30 · 2017: 29 · 2016: 27 · 2015: 23 · 2014: 38 · 2013: 25 · 2012: 30
- FWCI
- 3.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- model organisms, origin of multicellularity, phylogeny, comparative genomics
- MeSH terms
- Animals, Archaea, Bacteria, Chronology as Topic, Biological Evolution, Fungi, Humans, Models, Biological, Phylogeny, Plants, Eukaryota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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