Matrix metalloproteinases as modulators of inflammation and innate immunity

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  1. Tuberculosis, Pulmonary Cavitation, and Matrix Metalloproteinases
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  2. Elevated MMP-12 protein levels in induced sputum from patients with COPD
    Ingel Demedts · 2005 · Thorax
  3. Proteomics Discovery of Metalloproteinase Substrates in the Cellular Context by iTRAQ™ Labeling Reveals a Diverse MMP-2 Substrate Degradome
    Richard A. Dean, Christopher M. Overall · 2007 · Molecular & Cellular Proteomics
  4. Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis
    Catherine W.M. Ong, Paul T. Elkington, Sara Brilha, César Ugarte‐Gil, Maite Tome, Liku B. Tezera, Przemyslaw J. Pabisiak, Rachel Moores, Tarangini Sathyamoorthy, Vimal Patel et al. · 2015 · PLoS Pathogens
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    Jennifer L. Herington, Kaylon L. Bruner‐Tran, John Alexander Lucas, Kevin G. Osteen · 2011 · Expert Review of Clinical Immunology
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  8. Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke
    Atsushi Mizuma, Midori Anne Yenari · 2017 · Frontiers in Neurology
  9. Mechanistic overview of reactive species-induced degradation of the endothelial glycocalyx during hepatic ischemia/reperfusion injury
    Rowan F. van Golen, Thomas M. van Gulik, Michal Heger · 2012 · Free Radical Biology and Medicine
  10. Systematic review of molecular mechanism of action of negative-pressure wound therapy
    Graeme E. Glass, Gëorge F. Murphy, A Esmaeili, LM Lai, Jagdeep Nanchahal · 2014 · British journal of surgery
  11. Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways
    Ridnour, Lisa A., Windhausen, Alisha N., Isenberg, Jeffrey S., Yeung, Nolan, Thomas, Douglas D., Vitek, Michael P., Roberts, David D., Wink, David A. · 2007 · Proceedings of the National Academy of Sciences
  12. Inflammation and Disruption of the Mucosal Architecture in Claudin-7–Deficient Mice
    Lei Ding, Zhe Lü, Oded Foreman, Rodney Tatum, Qun Lu, Randall H. Renegar, Jian Ping Cao, Yan–Hua Chen · 2011 · Gastroenterology
  13. Degradomics: Systems biology of the protease web. Pleiotropic roles of MMPs in cancer
    Christopher M. Overall, Richard A. Dean · 2006 · Cancer and Metastasis Reviews
  14. Extracellular matrix regulation of inflammation in the healthy and injured spinal cord
    Andrew D. Gaudet, Phillip G. Popovich · 2014 · Experimental Neurology
  15. Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways
    Lolmede, Karine, Campana, Lara, Vezzoli, Michela, Bosurgi, Lidia, Tonlorenzi, Rossana, Clementi, Emilio, Bianchi, Marco E, Cossu, Giulio, Manfredi, Angelo A, Brunelli, Silvia et al. · 2009 · Journal of Leukocyte Biology
  16. Cytokines in ovarian folliculogenesis, oocyte maturation and luteinisation
    Sarah L. Field, Tathagata Dasgupta, Michele Cummings, Nicolas Michel Orsi · 2013 · Molecular Reproduction and Development
  17. Transcriptome Profiling and Functional Analyses of the Zebrafish Embryonic Innate Immune Response to Salmonella Infection
    Oliver W. Stockhammer, Anna Zakrzewska, Zoltán Hegedüs, Herman P. Spaink, Annemarie H. Meijer · 2009 · The Journal of Immunology
  18. Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury
    Sarah A. Busch, Kevin P. Horn, Daniel J. Silver, Jerry Silver · 2009 · Journal of Neuroscience
  19. Neutrophils: a cornerstone of liver ischemia and reperfusion injury
    Thiago Henrique Caldeira de Oliveira, Pedro Elias Marques, Paul Proost, Mauro Martins Teixeira · 2017 · Laboratory Investigation
  20. LPS Responsiveness and Neutrophil Chemotaxis In Vivo Require PMN MMP-8 Activity
    Angus M. Tester, Jennifer H. Cox, Andrea R. Connor, Amanda E. Starr, Richard A. Dean, Xosé S. Puente, Carlos López-Otı́n, Christopher M. Overall · 2007 · PLoS ONE
  21. Proteinases in cutaneous wound healing
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  23. The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas
    Helen Könnecke, Ingo Bechmann · 2013 · Clinical and Developmental Immunology
  24. Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation
    Meilang Xue, Kelly J. McKelvey, Kaitlin Shen, Nikita Minhas, LYN M. MARCH, Sang‐Youel Park, Chris Jackson · 2014 · Lara D. Veeken
  25. Tissue Plasminogen Activator (tPA) and Matrix Metalloproteinases in the Pathogenesis of Stroke: Therapeutic Strategies
    A. Muralikrishna Rao, James Franklin Hatcher · 2008 · CNS & Neurological Disorders - Drug Targets
  26. The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis
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  27. Metalloproteinases: A parade of functions in matrix biology and an outlook for the future
    Suneel Apte, William C. Parks · 2015 · Matrix Biology
  28. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis
    Hiroshi Uchinami, Ekihiro Seki, David A. Brenner, Jeanine M D'Armiento · 2006 · Hepatology
  29. Matrix metalloproteases and PAR1 activation
    Karyn M. Austin, Lidija Covic, Athan Kuliopulos · 2012 · Blood
  30. Matrix Metalloproteinases as Drug Targets in Infections Caused by Gram-Negative Bacteria and in Septic Shock
    Ineke Vanlaere, Claude Libert · 2009 · Clinical Microbiology Reviews
  31. The role of inflammatory mediators and matrix metalloproteinases (MMPs) in the progression of osteoarthritis
    Anwesha Mukherjee, Bodhisatwa Das · 2024 · Biomaterials and Biosystems
  32. Classical Macrophage Activation Up-Regulates Several Matrix Metalloproteinases through Mitogen Activated Protein Kinases and Nuclear Factor-κB
    Wei‐Chun Huang, Graciela B. Sala‐Newby, Angela Susana, Jason Lee Johnson, Andrew C. Newby · 2012 · PLoS ONE
  33. Recent advances of redox-responsive nanoplatforms for tumor theranostics
    Miaomiao Chen, Dapeng Liu, Fusheng Liu, Yingnan Wu, Xiaojun Peng, Fengling Song · 2021 · Journal of Controlled Release
  34. The Hemopexin and O-Glycosylated Domains Tune Gelatinase B/MMP-9 Bioavailability via Inhibition and Binding to Cargo Receptors
    Philippe E. Van den Steen, Ilse Van Aelst, Vibeke Hvidberg, Heléne Piccard, Pierre Fiten, Christian Borch Jacobsen, Søren K. Moestrup, Simon A. Fry, Louise Royle, Mark R. Wormald et al. · 2006 · Journal of Biological Chemistry
  35. The gelatinases, MMP-2 and MMP-9, as fine tuners of neuroinflammatory processes
    Melanie‐Jane Hannocks, Xueli Zhang, Hanna Gerwien, Anna A. Chashchina, Miriam Burmeister, Éva Korpos, Jian Song, Lydia M. Sorokin · 2017 · Matrix Biology
  36. The tumor microenvironment in hepatocellular carcinoma (Review)
    Massimo Libra · 2012 · International Journal of Oncology
  37. Alternative activation deprives macrophages of a coordinated defense program to Mycobacterium tuberculosis
    Antje Kahnert, Peter J. Seiler, Maik Stein, Silke Bandermann, Karin Hahnke, Hans‐Joachim Mollenkopf, Stefan H. E. Kaufmann · 2006 · European Journal of Immunology
  38. Next generation matrix metalloproteinase inhibitors — Novel strategies bring new prospects
    Maxim Levin, Yael Udi, Inna Solomonov, Irit Sagi · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  39. Targeting inflammation in diabetes: Newer therapeutic options
    Neeraj Kumar Agrawal · 2014 · World Journal of Diabetes
  40. Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain
    Penghua Wang, Jianfeng Dai, Fengwei Bai, Kok‐Fai Kong, Susan J. Wong, Ruth R. Montgomery, Joseph A. Madri, Erol Fikrig · 2008 · Journal of Virology
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  42. Immunity and Immunopathology in the Tuberculous Granuloma
    Antonio J. Pagán, Lalita Ramakrishnan · 2014 · Cold Spring Harbor Perspectives in Medicine
  43. Proteomic Identification of In Vivo Substrates for Matrix Metalloproteinases 2 and 9 Reveals a Mechanism for Resolution of Inflammation
    Kendra J. Greenlee, David Brian Corry, David A. Engler, Risë K. Matsunami, Philippe A. Tessier, Richard G. Cook, Zena Werb, Farrah Kheradmand · 2006 · The Journal of Immunology
  44. Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells
    Nils P. Hailer · 2007 · Progress in Neurobiology
  45. Matrix metalloproteinase inhibition therapy for vascular diseases
    Andrew C. Newby · 2012 · Vascular Pharmacology
  46. Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases
    Giampiero Pietrocola, Giulia Nobile, Simonetta Rindi, Pietro Speziale · 2017 · Frontiers in Cellular and Infection Microbiology
  47. The Metabolism of Proline as Microenvironmental Stress Substrate
    James Ming Phang, Jui Pandhare, Yongmin Liu · 2008 · Journal of Nutrition
  48. Cellular Mechanisms of Tissue Fibrosis. 3. Novel mechanisms of kidney fibrosis
    Gabriela Campanholle, Giovanni Ligresti, Sina A. Gharib, Jeremy S. Duffield · 2013 · American Journal of Physiology-Cell Physiology
  49. Stimulus-cleavable chemistry in the field of controlled drug delivery
    Yufei Xue, Hua Bai, Bo Peng, Bin Fang, Jonathan B. Baell, Lin Li, Wei Huang, Nicolas Hans Voelcker · 2021 · Chemical Society Reviews
  50. Inflammatory bowel disease biomarkers
    Dandan Liu, Varma Saikam, Katie A. Skrada, Didier Merlin, Suri S. Iyer · 2022 · Medicinal Research Reviews
  51. Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis
    Kyriakides, Themis R., Wulsin, Drausin, Skokos, Eleni A., Fleckman, Philip, Pirrone, Annalisa, Shipley, J. Michael, Senior, Robert M., Bornstein, Paul · 2009 · Matrix Biology
  52. Stimuli‐Responsive Delivery of Growth Factors for Tissue Engineering
    Moyuan Qu, Xing Jiang, Xingwu Zhou, Canran Wang, Qingzhi Wu, Li Mei Ren, Jixiang Zhu, Songsong Zhu, Peyton J. Tebon, Wujin Sun et al. · 2020 · Advanced Healthcare Materials
  53. The Extracellular Matrix: Its Composition, Function, Remodeling, and Role in Tumorigenesis
    Kevin Dzobo, Collet Dandara · 2023 · Biomimetics
  54. Role for Matrix Metalloproteinase 9 in Granuloma Formation during PulmonaryMycobacterium tuberculosisInfection
    Jennifer L. Taylor, Jessica M. Hattle, Steve Dreitz, JoLynn M. Troudt, Linda S. Izzo, Randall J. Basaraba, Ian M. Orme, Lynn McCormick Matrisian, Angelo A. Izzo · 2006 · Infection and Immunity
  55. Matrix Metalloproteinase Inhibitors as Investigative Tools in the Pathogenesis and Management of Vascular Disease
    Mina Mecheal Benjamin, Raouf A. Khalil · 2012 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
  56. Matrix metalloproteinases in asthma and COPD
    Ingel Demedts, Guy Brusselle, Ken R. Bracke, Karim Y. Vermaelen, ROMAIN A. PAUWELS · 2005 · Current Opinion in Pharmacology
  57. Matrix metalloprotease regulation of neuropathic pain
    Ru‐Rong Ji, Zhen‐Zhong Xu, Xiaoying Wang, Eng H. Lo · 2009 · Trends in Pharmacological Sciences
  58. Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
    Tarik Hadi, Ludovic Boytard, Michele Silvestro, Dornazsadat Alebrahim, Samson T. Jacob, Jordyn Feinstein, Krista Barone, Wes Spiro, Susan B. Hutchison, Russell Simon et al. · 2018 · Nature Communications
  59. Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia
    Chatmanee Lertudomphonwanit, Reena Mourya, Lin Fei, Yue Zhang, Sridevi Gutta, Li Yang, Kevin E. Bove, Pranavkumar Shivakumar, Jorge A. Bezerra · 2017 · Science Translational Medicine
  60. Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage
    Thian Kui Tan, Guoping Zheng, Tzu-Ting Hsu, So Ra Lee, Jianlin Zhang, Ye Zhao, Xinrui Tian, Yi‐Ping Wang, Yuan Min Wang, Qi Cao et al. · 2013 · Laboratory Investigation
  61. PGE2-induced metalloproteinase-9 is essential for dendritic cell migration
    Jui-Hung Jimmy Yen, Tanzilya Khayrullina, Doina Ganea · 2007 · Blood
  62. Role of Fluid Dynamics and Inflammation in Intracranial Aneurysm Formation
    Alexis S. Turjman, Francis Turjman, Elazer Reuven Edelman · 2014 · Circulation
  63. Matrix metalloproteinases in inflammatory bowel disease: Boon or a bane?
    Anupama Ravi, Pallavi Garg, Shanthi V. Sitaraman · 2006 · Inflammatory Bowel Diseases
  64. Biomarkers of abdominal aortic aneurysm progression. Part 2: inflammation
    Femke A. M. V. I. Hellenthal, Willem A. Buurman, Will K. W. H. Wodzig, Geert Willem H. Schurink · 2009 · Nature Reviews Cardiology
  65. Matrix metalloproteinases, their production by monocytes and macrophages and their potential role in HIV-related diseases
    Nicole L. Webster, Suzanne M. Crowe · 2006 · Journal of Leukocyte Biology
  66. The role of endogenous and exogenous enzymes in chronic wounds: a focus on the implications of aberrant levels of both host and bacterial proteases in wound healing
    McCarty, Sara M., Cochrane, Christine A., Clegg, Peter D., Percival, Steven L. · 2012 · Wound Repair and Regeneration
  67. Role of matrix metalloproteinases in epithelial migration
    Peter Chen, William C. Parks · 2009 · Journal of Cellular Biochemistry
  68. Nitric oxide and reactive nitrogen species in airway epithelial signaling and inflammation
    Peter F. Bove, Albert van der Vliet · 2006 · Free Radical Biology and Medicine
  69. Microenvironment of the Involuting Mammary Gland Mediates Mammary Cancer Progression
    Pepper S. Schedin, Jenean O’Brien, Michael C. Rudolph, Torsten Stein, Virginia F. Borges · 2007 · Journal of Mammary Gland Biology and Neoplasia
  70. Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation
    Zhang, Qiu-Shuang, Heng, Yang, Yuan, Yu-He, Chen, Nai-Hong · 2017 · Toxicology Letters
  71. Review: Manipulating the extracellular matrix and its role in brain and spinal cord plasticity and repair
    Emily R. Burnside, Elizabeth J. Bradbury · 2013 · Neuropathology and Applied Neurobiology
  72. Novel roles of Src in cancer cell epithelial-to-mesenchymal transition, vascular permeability, microinvasion and metastasis
    Ami B. Patel, Harika Sabbineni, Andrea Clarke, Payaningal R. Somanath · 2016 · Life Sciences
  73. An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization
    Andrew Weaver, Angelika Goncalves DaSilva, Robert K. Nuttall, Dylan R. Edwards, Steven David Shapiro, Serge Rivest, Voon Wee Yong · 2005 · The FASEB Journal
  74. Regulation of matrix metalloproteinase‐2 (MMP‐2) activity by phosphorylation
    Meltem Sarıahmetoğlu, Bryan D. Crawford, Hernando León, Jolanta Sawicka, Laiji Li, Barbara J. Ballermann, Charles F.B. Holmes, Luc G. Berthiaume, Andrew Holt, Grzegorz Sawicki et al. · 2007 · The FASEB Journal
  75. Pharmacoproteomics of a Metalloproteinase Hydroxamate Inhibitor in Breast Cancer Cells: Dynamics of Membrane Type 1 Matrix Metalloproteinase-Mediated Membrane Protein Shedding
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  76. Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases
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  77. Human Immunology of Tuberculosis
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  78. Dementia of the eye: the role of amyloid beta in retinal degeneration
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  79. Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages
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  80. 1α,25‐dihydroxyvitamin D3 inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection
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  81. A secreted MMP is required for reepithelialization during wound healing
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  82. Manipulating cell fate: dynamic control of cell behaviors on functional platforms
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  83. Matrix metalloproteases: Underutilized targets for drug delivery
    Deepali G. Vartak, Richard A. Gemeinhart · 2007 · Journal of drug targeting
  84. Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9
    Susan MacLauchlan, Eleni A. Skokos, Norman A. Meznarich, Dana H Zhu, Sana Raoof, J. Michael Shipley, Robert M. Senior, PAUL K. BORNSTEIN, Themis R. Kyriakides · 2009 · Journal of Leukocyte Biology
  85. Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host?
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  86. Cutting Edge: Tissue Inhibitor of Metalloproteinase 3 Regulates TNF-Dependent Systemic Inflammation
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  87. MMP9 modulates tight junction integrity and cell viability in human airway epithelia
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  88. Matrix metalloproteinase 9 modulates collagen matrices and wound repair
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  89. Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes
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  90. Carvacrol suppresses LPS-induced pro-inflammatory activation in RAW 264.7 macrophages through ERK1/2 and NF-kB pathway
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  91. Activities of the Matrix Metalloproteinase Stromelysin-2 (MMP-10) in Matrix Degradation and Keratinocyte Organization in Wounded Skin
    Monika Krampert, Wilhelm Bloch, Takako Sasaki, Philippe Bugnon, Thomas Rülicke, Eckhard Wolf, Monique Aumailley, William C. Parks, Sabine Werner · 2004 · Molecular Biology of the Cell
  92. The immunomodulatory role of matrix metalloproteinases in colitis-associated cancer
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  93. Natural antioxidant polyphenols on inflammation management: Anti-glycation activity vs metalloproteinases inhibition
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  94. Matrix metalloproteinases in emphysema
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  95. Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection
    Annemarie H. Meijer, Fons J. Verbeek, Enrique Salas Vidal, Maximiliano Corredor-Adámez, Jeroen Bussman, Astrid M. van der Sar, Georg Otto, Robert Geisler, Herman P. Spaink · 2005 · Molecular Immunology
  96. Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases
    Naomi F. Walker, Simon O Clark, Tolu Oni, Núria Andreu, Liku B. Tezera, Shivani Singh, Luísa Saraiva, Bernadette Pedersen, Dominic L.F. Kelly, Julia A. Tree et al. · 2012 · American Journal of Respiratory and Critical Care Medicine
  97. Neutrophil MMP-9 Proenzyme, Unencumbered by TIMP-1, Undergoes Efficient Activation in Vivo and Catalytically Induces Angiogenesis via a Basic Fibroblast Growth Factor (FGF-2)/FGFR-2 Pathway
    Veronica C. Ardi, Philippe E. Van den Steen, Ghislain Opdenakker, Bernhard Schweighofer, Elena I. Deryugina, James P. Quigley · 2009 · Journal of Biological Chemistry
  98. AND-gate contrast agents for enhanced fluorescence-guided surgery
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  99. ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets
    Daniela Yildiz, Stefan Uhlig, Andreas Ludwig · 2014 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  100. Airway Epithelial Cell Migration and Wound Repair by ATP-mediated Activation of Dual Oxidase 1
    Umadevi V. Wesley, Peter F. Bove, Milena Hristova, Sean M. McCarthy, Albert van der Vliet · 2006 · Journal of Biological Chemistry