The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
The broad-spectrum antiviral functions of IFIT and IFITM proteins
Open accessAbstract
Over the past few years, several groups have identified new genes that are transcriptionally induced downstream of type I interferon (IFN) signalling and that inhibit infection by individual or multiple families of viruses. Among these IFN-stimulated genes with antiviral activity are two genetically and functionally distinct families — the IFN-induced protein with tetratricopeptide repeats (IFIT) family and the IFN-induced transmembrane protein (IFITM) family. This Review focuses on recent advances in identifying the unique mechanisms of action of IFIT and IFITM proteins, which explain their broad-spectrum activity against the replication, spread and pathogenesis of a range of human viruses.
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Cites
Innate immune recognition of viral infection
Kawai, T., & Akira, S. (2006) · Nature Immunology · doi:10.1038/ni1303 · Cited by 1,899
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
Ogawa, S., Lozach, J., Benner, C., Pascual, G., Tangirala, R. K., Westin, S., Hoffmann, A., Subramaniam, S., David, M., Rosenfeld, M. G., et al. (2005) · Cell · doi:10.1016/j.cell.2005.06.029 · Cited by 647
The Interferon Inducible Gene: Viperin
Fitzgerald, K. A. (2011) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2010.0127 · Cited by 163
Cited by
Interferon-stimulated genes: A complex web of host defenses
Schneider, W. M., Chevillotte, M. D., & Rice, C. M. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120231 · Cited by 3,067
Interferon-Stimulated Genes: What Do They All Do?
Schoggins, J. W. (2019) · Annual Review of Virology · doi:10.1146/annurev-virology-092818-015756 · Cited by 1,036
Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
Zhou, Z., Ren, L., Zhang, L., Zhong, J., Xiao, Y., Jia, Z., Guo, L., Yang, J., Wang, C., Jiang, S., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.04.017 · Cited by 938
Innate immunity in tuberculosis: host defense vs pathogen evasion
Liu, C. H., Liu, H., & Ge, B. (2017) · Cellular & Molecular Immunology · doi:10.1038/cmi.2017.88 · Cited by 532
Romano, M., Ruggiero, A., Squeglia, F., Maga, G., & Berisio, R. (2020) · Cells · doi:10.3390/cells9051267 · Cited by 527
Metadata
- Authors
- Diamond, M. S., & Farzan, M.
- Venue
- Nature Reviews Immunology
- Published
- 2012-12-14
- Volume
- 13
- Issue
- 1
- Pages
- 46-57
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2076198632
- Cited by
- 849
- References
- 3
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- bronze
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