Progeria syndromes and ageing: what is the connection?

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Items 201–300 of 381

1. Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)
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2. Key Molecular Mechanisms of Aging, Biomarkers, and Potential Interventions
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3. Rejuvenation by Partial Reprogramming of the Epigenome
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4. Molecular Interactions between Dietary Lipids and Bone Tissue during Aging
   José M. Romero‐Márquez, Alfonso Varela‐López, María D. Navarro‐Hortal, Alberto Badillo-Carrasco, Tamara Yuliett Forbes-Hernández, Francesca Giampieri, Irma Dominguez Azpíroz, Lorena Madrigal, Maurizio Antonio Battino, José Luis Quiles · 2021 · International Journal of Molecular Sciences
5. Speeding up the clock: The past, present and future of progeria
   Vijay Swahari, Ayumi Nakamura · 2015 · Development Growth & Differentiation
6. Premature aging in genetic diseases: what conclusions can be drawn for physiological aging
   Filip Milosic, Markus Hengstschläger, Selma Osmanagic‐Myers · 2024 · Frontiers in Aging
7. Can Be miR-126-3p a Biomarker of Premature Aging? An Ex Vivo and In Vitro Study in Fabry Disease
   Alessia Lo Curto, Simona Taverna, Maria Assunta Costa, Rosa Passantino, Giuseppa Augello, Giorgia Adamo, Anna Aiello, Paolo Colomba, Carmela Zizzo, Marco Zora et al. · 2021 · Cells
8. Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle
   Ignacio Navas‐Enamorado, Michel Bernier, Gloria Brea‐Calvo, Rafael de Cabo · 2017 · Ageing Research Reviews
9. Hautalterung
   Evgenia Makrantonaki, Mona Vogel, Karin Scharffetter‐­Kochanek, Christos C. Zouboulis · 2015 · Der Hautarzt
10. Ключевые молекулярные механизмы старения, биомаркеры и потенциальные интервенции
    Ekaterina Proshkina, И. А. Соловьёв, Mikhail Vyacheslavovich Shaposhnikov, A.A. Moskalev · 2020 · Molecular Biology
11. Clinical and laboratory skin biomarkers of organ-specific diseases
    Christos C. Zouboulis, Evgenia Makrantonaki · 2018 · Mechanisms of Ageing and Development
12. Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles
    Alessandro Agostini, Laura Mondragón, Andrea Bernardos, Ramón Martínez‐Máñez, María Dolores Marcos, Félix Sancenón, Juán Soto, Ana María Costero, Cristina Manguán-García, Rosario Perona et al. · 2012 · Angewandte Chemie
13. Transcriptional profiling reveals progeroid Ercc1 -/Δ mice as a model system for glomerular aging
    Bernhard Schermer, Valerie Bartels, Peter Frommolt, Bianca Hermine Habermann, Fabian Braun, Joachim Ludwig Schultze, Marianne Roodbergen, Jan H.J. Hoeijmakers, Björn Schumacher, Peter Nürnberg et al. · 2013 · BMC Genomics
14. Les théories du vieillissement
    C. de Jaeger, Patrick Cherin · 2011 · Médecine & longévité
15. ATM modulates subventricular zone neural stem cell maintenance and senescence through Notch signaling pathway
    Dong, Chuanming, Wang, Xianli, Sun, Lixin, Zhu, Liang, Yang, Danjing, Gao, Shane, Zhang, Wenjun, Ling, Bin, Liang, Aibin, Gao, Zhengliang et al. · 2022 · Stem Cell Research
16. Loss ofVHLpromotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity
    Youn‐Sang Jung, Su-Jin Lee, Sun-Hye Lee, Ji-Yun Chung, Youn-Jin Jung, Sang‐Hyun Hwang, Nam‐Chul Ha, Bum-Joon Park · 2013 · Cell Cycle
17. DNA damage contributes to age‐associated differences in SARS‐CoV ‐2 infection
    Rui Jin, Chang Niu, Fengyun Wu, Sixin Zhou, Tao Han, Zhe Zhang, Entao Li, Xiaona Zhang, Shanrong Xu, Jiadong Wang et al. · 2022 · Aging Cell
18. Age-dependent down-regulation of DNA polymerase δ1 in human lymphocytes
    Jinling Wang, Hong-Lin Guo, Peichang Wang, Chengeng Liu · 2012 · Molecular and Cellular Biochemistry
19. Functional relevance of miRNAs in premature ageing
    Xurde M. Caravia, David Roiz‐Valle, Alba Morán-Álvarez, Carlos López-Otı́n · 2017 · Mechanisms of Ageing and Development
20. Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model
    Gustavo Satoru Kajitani, Lear E. Brace, Jose Humberto Trevino-Villarreal, Kaspar M. Trocha, Michael Robert MacArthur, Sarah C. Vose, Dorathy Vargas, Roderick Terry Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck et al. · 2021 · Aging
21. Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?
    Alejandro Pineiro Ugalde, Guillermo Mariño, Carlos López-Otı́n · 2010 · Aging
22. Progeria accelerates adult stem cell aging
    Regina Brunauer, Brian Keith Kennedy · 2015 · Science
23. Structure and Function of the Skin
    John Alexander McGrath, Jouni Uitto · 2016 · Wiley eBooks
24. Identifying Age‐Modulating Compounds Using a Novel Computational Framework for Evaluating Transcriptional Age
    Chao Zhang, Nathalie G. Saurat, Daniela Cornacchia, Sun Young Chung, Trisha Sikder, Adrianne Nemchik, Andrew P. Minotti, Lorenz Studer, Doron Betel · 2025 · Aging Cell
25. celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish
    Chunmei Li, Carrie L. Barton, Katrin Henke, Jake Daane, Stephen B. Treaster, Joana Caetano‐Lopes, Robyn L Tanguay, Matthew P. Harris · 2020 · eLife
26. Progress in and Prospects of Genome Editing Tools for Human Disease Model Development and Therapeutic Applications
    Hong Thi Lam Phan, Kyoungmi Kim, Ho Lee, Je Kyung Seong · 2023 · Genes
27. Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome
    Clément Crochemore, Claudia Chica, Paolo Garagnani, Giovanna Lattanzi, Steve Horvath, Alain R. Sarasin, Claudio Franceschi, Maria Giulia Bacalini, Miria Ricchetti · 2023 · Aging Cell
28. MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts
    Xing-dong Xiong, Hwa Jin Jung, Saurabh Gombar, Jung Yoon Park, Chun-long Zhang, Huiling Zheng, Jie Ruan, Jiang-bin Li, Matt R. Kaeberlein, Brian Keith Kennedy et al. · 2015 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
29. Cellular parabiosis and the latency of age-related diseases
    Miroslav Radman · 2019 · Open Biology
30. Reversal of laminopathies: the curious case of SUN1
    Ya‐Hui Chi, Chia-yen Chen, Kuan‐Teh Jeang · 2012 · Nucleus
31. Understanding Vascular Diseases: Lessons From Premature Aging Syndromes
    Yuichi Ikeda, Hidetoshi Kumagai, Yoshihiro Motozawa, Jun-ichi Suzuki, Hiroshi Akazawa, Issei Komuro · 2015 · Canadian Journal of Cardiology
32. Role of mismatch repair in aging
    Jie Wen, Yangyang Wang, Minghao Yuan, Zhenting Huang, Qian Zou, Yinshuang Pu, Bin Zhao, Zhiyou Cai · 2021 · International Journal of Biological Sciences
33. Aging Epigenetics
    Duygu Ucar, Bérénice Anath Benayoun · 2017 · Elsevier eBooks
34. The Dual Role of Extracellular Vesicles in Aging and Age-Related Diseases: Pathophysiology and Therapeutic Potential
    Yifan Zhu, Xiansong Fang, Shuli Zhang, Yiqun Liao, Haihong Lin, Puwen Chen, Mei Yang, J.J. Huang, Xiaoling Wang · 2026 · International Journal of Nanomedicine
35. Double strand breaks may be a missing link between entropy and aging
    Peter Lenárt, Julie Bienertová Vašků · 2016 · Mechanisms of Ageing and Development
36. Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide
    Barış Akıncı, Shireesha Sankella, Christopher J. Gilpin, Keiichi Ozono, Abhimanyu Garg, Anil K. Agarwal · 2016 · Molecular Case Studies
37. The dual guardians of cellular stability: exploring nesprin and lamin in senescence
    Ziyi Zhou, Qin Qin, Cengyuan Dong, Yangyuanzhi Liu, Chunyu Cao, Lin Teng · 2025 · Cell Death and Disease
38. Insights into targeting cellular senescence with senolytic therapy: The journey from preclinical trials to clinical practice
    Peng Chen, Yulai Wang, Benhong Zhou · 2024 · Mechanisms of Ageing and Development
39. Ecobiological approach to research regarding ageing and diseases
    Miroslav Radman · 2019 · European Journal of Dermatology
40. Opportunities and Challenges in Stem Cell Aging
    Bagher A. Larijani, Najmeh Foroughi Heravani, Setareh Alaei, Mostafa Rezaei–Tavirani, Sepideh Alavi-Moghadam, Moloud Payab, Parisa Goodarzi, Akram Tayanloo-Beik, Hamid Reza Aghayan, Babak Arjmand · 2021 · Advances in experimental medicine and biology
41. Assessment of the Aging of the Brown Adipose Tissue by 1 8 F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna −/−
    Zhengjie Wang, Xiaolong Xu, Yi Liu, Yongheng Gao, Ennui Ma, Welding Yang, Jing Wang, Baohua Liu, Jing Wang · 2018 · Contrast Media & Molecular Imaging
42. Quantification of the Lamin A/C Transcript Variants in Cancer Cell Lines by Targeted Absolute Quantitative Proteomics and Correlation with mRNA Expression
    Wedad Saeed Al-Qahtani, Mai Abduljabbar, Entissar S. AlSuhaibani, Anas M. Abdel Rahman, Ahmad Aljada · 2019 · International Journal of Molecular Sciences
43. WITHDRAWN: Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
    Pierre Cau, Claire Laure Navarro, Karim Harhouri, Patrice Roll, Sabine Sigaudy, Élise Kaspi, Sophie Perrin, Annachiara De Sandre‐Giovannoli, Nicolas Lévy · 2014 · Seminars in Cell and Developmental Biology
44. Precise progerin targeting using RfxCas13d: A therapeutic avenue for Hutchinson-Gilford progeria syndrome
    Unbin Chae, Hae-Jun Yang, Hanseop Kim, Seung Hwan Lee, Dong Gil Lee, Jeong Young Koo, Seung-Min Ha, S. Peter Bak, Mina Joo, Hyun Hee Nam et al. · 2025 · Molecular Therapy
45. Identification of COMMD1 as a novel lamin A binding partner
    Zhiwen Jiang, Wei‐Chun Chen, Jing Zhou, Qi Peng, Huiling Zheng, Yuan Yuan, Hongjing Cui, Wei Zhao, Xuerong Sun, Zhongjun Zhou et al. · 2019 · Molecular Medicine Reports
46. A Review on the Efficacy of Plant-derived Bio-active Compounds Curcumin and Aged Garlic Extract in Modulating Cancer and Age-related Diseases
    Diptimayee Das, Murhekar Kanchan, Abhijit Mitra, Mohamed Y. Zaky, Surajit Pathak, Antara Banerjee · 2023 · Current Clinical Pharmacology
47. In search of lost time: age and the promise of induced pluripotent stem cell models of the brain
    Richard Milne · 2016 · New Genetics and Society
48. When nature’s robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies
    Julie A. Reisz, Alexander S. Barrett, Travis G. Nemkov, Kirk Charles Hansen, Angelo D’Alessandro · 2018 · Expert Review of Proteomics
49. Accelerated Aging in Cyclophilin B–Deficient Mice Downstream of p21‐Cip1 /Waf1
    Ying Zhang, Robert J. Pignolo, Richard J. Bram · 2022 · JBMR Plus
50. p.Pro4Arg mutation in LMNA gene: a new atypical progeria phenotype without metabolism abnormalities
    Hong Guo, Na Luo, Fei Hao, Yun Bai · 2014 · Gene
51. A high prevalence of myeloid malignancies in progeria with Werner syndrome is associated with p53 insufficiency
    Hisaya Kato, Yoshiro Maezawa, Dai Nishijima, Eisuke Iwamoto, June Takeda, Takashi Kanamori, Masaya Yamaga, Tatsuzo Mishina, Yusuke Takeda, Shintaro Izumi et al. · 2022 · Experimental Hematology
52. Lamin A to Z in normal aging
    Stanley R. Primmer, Chen‐Yu Liao, Oona M.P. Kummert, Brian Keith Kennedy · 2022 · Aging
53. Dental and craniofacial characteristics in a patient with Hutchinson–Gilford progeria syndrome
    C. Reichert, Lina Gölz, Werner Götz, M. Wolf, James Deschner, Andreas Jäger · 2014 · Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie
54. Splicing Variants, Protein-Protein Interactions, and Drug Targeting in Hutchinson-Gilford Progeria Syndrome and Small Cell Lung Cancer
    Bae-Hoon Kim, Tae‐Gyun Woo, So‐mi Kang, Soyoung Park, Bum-Joon Park · 2022 · Genes
55. Identification of FAM96B as a novel prelamin A binding partner
    Xing‐dong Xiong, Junwen Wang, Huiling Zheng, Xia Jing, Zhenjie Liu, Zhongjun Zhou, Xinguang Liu · 2013 · Biochemical and Biophysical Research Communications
56. YeastMRXdeletions have short chronological life span and more triacylglycerols
    KanagaVijayan Dhanabalan, Ram Rajasekharan, Malathi Srinivasan · 2015 · FEMS Yeast Research
57. Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocations
    Patrick H. Maxwell · 2016 · BMC Genetics
58. Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford Progeria Syndrome (HGPS) revealed an impaired melanogenesis pathway in iPS-derived melanocytes
    Alessandra Lo Cicero, Manoubia Saidani, Jennifer Allouche, Anne-Laure Egesipe, Lucile Hoch, Céline Bruge, Sabine Sigaudy, Annachiara De Sandre‐Giovannoli, Nicolas Lévy, Christine Baldeschi et al. · 2018 · Scientific Reports
59. Syndromes Affecting Skin and Mucosa
    Ioannis George Koutlas · 2014 · Atlas of the Oral and Maxillofacial Surgery Clinics
60. Polμ Deficiency Increases Resistance to Oxidative Damage and Delays Liver Aging
    Beatriz Escudero, Daniel Lucas, Carmen Albo, Suveera Dhup, Jeffery W. Bacher, Aranzazu Sánchez, Margarita Fernández, José Rivera, Rosa María Carmona, Encarnación Fuster et al. · 2014 · PLoS ONE
61. Correction: Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna−/−Mice
    Richard L. Frock, Steven C. Chen, Dao‐Fu Dai, Ellie Frett, Carmen Lau, Christina Brown, Diana N. Pak, Yuexia Wang, Antoine Muchir, Howard J. Worman et al. · 2012 · PLoS ONE
62. The Anaphase-Promoting Complex/Cyclosome Is a Cellular Ageing Regulator
    Xiangdong Hu, Xuejiao Jin, Xiuling Cao, Beidong Liu · 2022 · International Journal of Molecular Sciences
63. Sex-specific preservation of neuromuscular function and metabolism following systemic transplantation of multipotent adult stem cells in a murine model of progeria
    Seth D. Thompson, Kelsey L. Barrett, Chelsea L. Rugel, Robin S Redmond, Alexia Rudofski, Jacob Kurian, Jodi L Curtin, Sudarshan Dayanidhi, Mitra Lavasani · 2023 · GeroScience
64. Anti-ageing natural supplements: the main players in promoting healthy lifespan
    Mehran Izadi, Nariman Sadri, Amirhossein Abdi, Mohammad Mahdi Raeis Zadeh, Dorsa Jalaei, Mohammad Mahdi Ghazimoradi, Sara Shouri, Safa Tahmasebi · 2024 · Nutrition Research Reviews
65. Postmitotic cell longevity–associated genes: a transcriptional signature of postmitotic maintenance in neural tissues
    Atahualpa Castillo-Morales, Jimena Monzón‐Sandoval, Araxi O. Urrutia, Humberto Gutiérrez · 2018 · Neurobiology of Aging
66. The macromolecular machinery of the nucleus in the senescence process
    Eric Almeida Xavier · 2022 · World Journal of Advanced Research and Reviews
67. Endogene Faktoren, Gene und Hautalterung
    Evgenia Makrantonaki, Gerd P. Pfeifer, Christos C. Zouboulis · 2016 · Der Hautarzt
68. One world, one woman
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69. Gene Editing in Stem Cells Hits the Target
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70. An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21
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71. PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradation
    Yuki Yoshioka, Yong Huang, Xiaocen Jin, Kien Xuan Ngo, Tomohiro Kumaki, Meihua Jin, Saori Toyoda, Sumire Takayama, Maiko Inotsume, Kyota Fujita et al. · 2024 · The EMBO Journal
72. Aging and Altered Gravity: A Cellular Perspective
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73. Aging and Anti-Aging in Hair and Hair Loss
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74. Implications of Multipotent Mesenchymal Stromal Cell Aging
    Ursula Stochaj, Mohamed Kodiha, Dominique Shum‐Tim, Inés Colmegna · 2013 · Regenerative Medicine
75. Cells, Niche, Fate: Meeting Report on the 6th International Meeting of the Stem Cell Network North Rhine Westphalia
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76. Aged Worms Erase Epigenetic History
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77. Effects of Psychological Stress on Telomeres as Genome Regulators
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78. BTG2 acts as an inducer of muscle stem cell senescence
    Baozhou Peng, Yihan Chen, Yaning Wang, Yixi Fu, Xinrui Zeng, Hanmeng Zhou, Zibaidan Abulaiti, Shuaiyu Wang, Hongbo Zhang · 2023 · Biochemical and Biophysical Research Communications
79. Terapias antienvejecimiento aplicadas a la enfermedad de Alzheimer
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80. Mouse models of testicular germ cell tumors
    Delphine Carouge, H.B. Joseph · 2012 · InTech eBooks
81. Dialing Down SUN1 for Laminopathies
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82. Meeting Report: International Symposium on the Genetics of Aging and Life History II
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83. Genetics of Human Longevity and Healthy Aging
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84. The role of the farnesyltransferase inhibitor lonafarnib in the treatment of Progeria
    Mark W. Kieran, Leslie B. Gordon, Monica E. Kleinman · 2013 · Expert Opinion on Orphan Drugs
85. Detection of Nuclear Envelope Alterations in Senescence
    Clea Bárcena, Fernando G. Osorio, José M.P. Freije · 2012 · Methods in molecular biology
86. Hutchinson-Gilford progeria syndrome cardiovascular disease and oxidative stress
    Vicente Andrés · 2011 · Frontiers in Bioscience-Scholar
87. Premature Ageing Syndromes
    Helga V. Toriello · 2011 · Wiley eBooks
88. Identification of the cytoplasmic DNA-Sensing cGAS-STING pathway-mediated gene signatures and molecular subtypes in prostate cancer
    Jie Yang, Zihan Xu, Weitao Zheng, Yifan Li, Qiang Wei, Lu Yang · 2024 · BMC Cancer
89. Epigenetic regulation of Hutchinson-Gilford progeria syndrome: from molecular mechanisms to targeted interventions
    Xuan Liu, Shuhui Yang, Jiaxiao Jiang, Shasha Dong, Yu Zhang · 2025 · Oral Science and Homeostatic Medicine
90. A human experimental model of laminopathy based on adult stem cells establishes the relevance of Oct1 transcription factor in the aging process
    2015 · Stem Cell and Translational Investigation
91. DNA damage, NF-κB and accelerated aging
    David George Le Couteur, David J. Handelsman · 2012 · Asian Journal of Andrology
92. Manifold epigenetics: A conceptual model that guides engineering strategies to improve whole-body regenerative health
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93. Progerin mRNA expression in non-HGPS patients is correlated with widespread shifts in transcript isoforms
    Reynold Yu, Huijing Xue, Wanru Lin, Francis S. Collins, Stephen M. Mount, Kan Cao · 2024 · NAR Genomics and Bioinformatics
94. Amelioration of premature aging in Werner syndrome stem cells by targeting SHIP/AKT pathway
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95. Progerin mRNA expression is elevated in aged human dermis and impairs TGF-β/Smad signaling
    Yaping Xiang, Zhaoping Qin, Chunfang Guo, Tianyuan He, Yingchun Liu, Taihao Quan · 2021 · Journal of Dermatological Science
96. More Than Skin Deep – the Effects of Ultraviolet Radiation on Cathepsin K and Progerin Expression in Cultured Dermal Fibroblasts
    Igor Aleksander Bednarski, Magdalena A. Ciążyńska, Jacek Kabziński, Ireneusz Majsterek, Dorota Sobolewska-Sztychny, Joanna Narbutt, Aleksandra Lesiak · 2021 · Clinical Cosmetic and Investigational Dermatology
97. Potential of nanoparticles and nanopolymers in treatment of age-associated diseases
    Fatemeh Saadatpour, Fatemeh Mohammadipanah, Nazanin Zohourian, Mahshid Hodjat · 2021 · Advances in Natural Sciences Nanoscience and Nanotechnology
98. The Nuclear Envelope in Cardiac Health and Disease
    Daniel Brayson, Catherine M. Shanahan · 2015 · Springer eBooks
99. Progeria Mouse Models
    Pablo Mayoral, Clea Bárcena, Carlos López-Otı́n · 2018 · Elsevier eBooks
100. Applications of CRISPR-Cas in Ageing Research
     Scott Haston, Sara Pozzi, José Mario González-Meljem · 2020 · Springer eBooks