NMD: a multifaceted response to premature translational termination

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Items 401–500 of 559

1. A novel nonsense mutation in the sedlin gene (SEDL) causes severe spondyloepiphyseal dysplasia tarda in a five-generation Chinese pedigree
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2. The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm
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3. The pre-mRNA retention and splicing complex controls expression of the Mediator subunit Med20
   Yang Zhou, Marcus Johansson · 2017 · RNA Biology
4. Selective profiling of ribosomes associated with yeast Upf proteins
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5. A novel TSC1 frameshift mutation c.1550_1551del causes tuberous sclerosis complex by aberrant splicing and nonsense‐mediated mRNA degradation (NMD) simultaneously in a Chinese family
   Cong Qiu, Chengyan Li, Xiaoyun Tong, Luoyang Dai, Wenda Liu, Yulie Xie, Qimei Zhang, Guohua Yang, Tao Li · 2020 · Molecular Genetics & Genomic Medicine
6. The Fungal Kingdom as a Rosetta Stone for biological discovery
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7. Plans within plans: post-transcriptional regulation governs macrophage responses
   Mackenzie H. Smith, Roy Parker, Kristin L. Patrick, Edward M.C. Courvan · 2025 · Trends in Immunology
8. Nonsense-mediated mRNA decay inhibits TRAF6-dependent anti-tumor immunity in colorectal cancer
   Yanmei Wang, Zhuo Wang, Chaoqun Wang, Yan Wu, Jiaqiu Li, Lifeng Feng, Minyan Hao, Hongchuan Jin, Jia Zhou, Xian Wang · 2025 · Cell Reports Medicine
9. SMG5 Inhibition Restrains Hepatocellular Carcinoma Growth and Enhances Sorafenib Sensitivity
   Nan Fang, Bing Liu, Qiuzhong Pan, Tingting Gong, Meixiao Zhan, Jingjing Zhao, Qi-jing Wang, Yan Tang, Yong-qiang Li, Jia He et al. · 2024 · Molecular Cancer Therapeutics
10. Silaffins as functional biomacromolecules in regulating frustule morphogenesis and biosilica properties
    Tengsheng Qiao, Lulu Wang, Yan Zhao, Yun Li, Guanpin Yang, Baohua Zhu, Kehou Pan · 2025 · International Journal of Biological Macromolecules
11. The patterns of alternative TSS usage explain the highly heterogeneous landscape of 5′UTR lengths in eukaryotes
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12. MicroRNA 4651 regulates nonsense-mediated mRNA decay by targeting SMG9 mRNA
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13. An overview of actionable and potentially actionable TSC1 and TSC2 germline variants in an online Database
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14. Non-coding RNA RMRP governs RAB31-dependent MMP secretion, enhancing ovarian cancer invasion
    Ki Jun Lee, Ji‐Hye Ahn, Jin Hyung Kim, Yong Sun Lee, Ju‐Seog Lee, Jae-Hyung Lee, Tae Jin Kim, Jung‐Hye Choi · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
15. RefSeq curation and annotation of antizyme and antizyme inhibitor genes in vertebrates
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16. A Novel c.776_777insA Mutation in CLN1 Leads to Infantile Neuronal Ceroid Lipofuscinosis
    Jake N. Miller, David A. Pearce · 2013 · Journal of Child Neurology
17. Nonsense Mutations in Eukaryotes
    Nadezhda A. Potapova · 2022 · Biochemistry (Moscow)
18. A splice variant of the human phosphohistidine phosphatase 1 (PHPT1) is degraded by the proteasome
    Raviteja Inturi, Marcus Wäneskog, Dimitriοs Vlachakis, Yeasmeen Ali, Pia Ek, Tanel Punga, Pernilla Bjerling · 2014 · The International Journal of Biochemistry & Cell Biology
19. Suppressing nonsense—a surprising function for 5‐azacytidine
    Ada Shao, Miles Wilkinson · 2014 · EMBO Molecular Medicine
20. Intron 2 of human beta-globin in 3′-untranslated region enhances expression of chimeric genes
    Anton P. Pereverzev, Nadezhda M. Markina, Yurii G. Yanushevich, Tatiana V. Gorodnicheva, Б. Э. Минасян, Konstantin A. Lukyanov, Nadya G. Gurskaya · 2014 · Russian Journal of Bioorganic Chemistry
21. A novel frameshift mutation of the NF1 gene in a Chinese pedigree with neurofibromatosis type 1
    Wei Zhu, Shi Lian, Xuefei Lin, Hui Chen · 2017 · Indian Journal of Dermatology Venereology and Leprology
22. Exploring Rice Genetic Resources to Improve Nutrient Use Efficiency
    Nahed Mohammed · 2018 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
23. Regulation of Flowering Time and Other Developmental Plasticities by 3’ Splicing Factor-Mediated Alternative Splicing in Arabidopsis thaliana
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24. A narrow range of transcript-error rates across the Tree of Life
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25. Ribosome Profiling for Novel Antigen Discovery
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26. Role of Sodium‐Dependent Vitamin C Transporter‐2 and Ascorbate in Regulating the Hypoxic Pathway in Cultured Glioblastoma Cells
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27. The role of nucleotide composition in premature termination codon recognition
    Fouad Zahdeh, Liran Carmel · 2016 · BMC Bioinformatics
28. mRNA Decay Pathways Use Translation Fidelity and Competing Decapping Complexes for Substrate Selection
    Alper Celik · 2017 · eScholarship@UMassChan
29. This Message Will Self-Destruct: NMD Regulates Axon Guidance
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30. The sticky business of Alphavirus capsid–host interactions
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31. Molecular mechanisms governing the formation of distinct Upf1-containing complexes in yeast
    Iuliia Iermak, Nicole R. Wilson Eisele, Katharina Kurscheidt, Matina-Jasemi Loukeri, J. Basquin, Fabien Bonneau, Lukas M Langer, Achim Keidel, Elena Conti · 2025 · Cell Reports
32. Genotype-phenotype characterization and functional reconstitution of pathogenic β-catenin variants from CTNNB1 syndrome patients
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33. Global effect of copper excess and deficiency in Saccharomyces cerevisiae proficient or deficient in nonsense-mediated mRNA decay
    Xinyi Zhang, Sunday Olaniyan, Xiayan Li, Bernd Zechmann, Mary Lauren Benton, Bessie Wanja Kebaara · 2025 · Genomics
34. ZNF496 as Candidate Gene for Neurodevelopmental Disorders: Identification of a Pathogenic De Novo Frameshift Variant
    Francesco Calı̀, Miriam Virgillito, Simone Treccarichi, Antonino Musumeci, Pinella Failla, Carla Papa, Rosanna Galati Rando, Concetta Federico, Salvatore Saccone, Mirella Vinci · 2025 · International Journal of Molecular Sciences
35. Nonsense-Mediated mRNA Decay: Mechanisms and Recent Implications in Cardiovascular Diseases
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36. Strategies to Correct Nonsense Mutations
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37. Presence of three mutations in the fumarylacetoacetate hydrolase gene in a patient with atypical symptoms of hereditary tyrosinemia type I
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38. A Novel PAX3 Mutation in a Chinese Family with Waardenburg Syndrome Type 1
    Shuling Li, Min Guo, Biao Ruan, Ya Liu, Xin Cui, Weiwei Han, Ruomei Li · 2020 · Genetic Testing and Molecular Biomarkers
39. Current Genetic Techniques in Neural Circuit Control of Feeding and Energy Metabolism
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40. Translational readthrough inducing drugs for the treatment of inherited retinal dystrophies
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41. How cells kill a "killer" messenger
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42. Diverse Mechanisms of Translation Regulation and Their Role in Cancer
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43. Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS
    Dan Jackson, Jenhao H. Ting, Paul D. Pozniak, Claire Meurice, Stephanie S. Schleidt, Anh Dao, Amy Huei‐Yi Lee, Eva Klinman, Kelly L. Jordan‐Sciutto · 2018 · Molecular and Cellular Neuroscience
44. rs67047829 genotypes of ERV3-1/ZNF117 are associated with lower body mass index in the Polish population
    Jeremy S. C. Clark, Konrad Podsiadło, Marta Sobalska‐Kwapis, Błażej Marciniak, Kamila Rydzewska, Andrzej Ciechanowicz, Thierry van de Wetering, Dominik Strapagiel · 2023 · Scientific Reports
45. The Burden of Hereditary Angioedema in a Large Family in Brazil
    Carolina Teló Gehlen Branco, Juliana Forte Mazzeu, Camila Lopes Veronez, Agatha Ribeiro Mendes, Andrezza Fabrízia Bertoli, Anete Sevciovic Grumach, João Bosco Pesquero, Jane da Silva · 2024 · International Archives of Allergy and Immunology
46. EPR spectroscopy in the study of ribosomal complexes
    Olesya A. Krumkacheva, Alexey A. Malygin, D. M. Graifer, M.I. Kolokolov, Elena G. Bagryanskaya · 2025 · Biophysical Reviews
47. SNP rs10748643 determines CD39 expression in T and NK cells through altering NFIC binding affinity rather than interfering with RNA splicing
    Chenxin Gan, Qian Vicky Wu, Jörg J. Goronzy, Yongchun Zhang, Lingjie Li, Huiming Sheng, Fengqin Fang · 2025 · Frontiers in Immunology
48. Co-transcriptional gene regulation in plants
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49. EEFSEC deficiency underlies a human selenopathy with primary neurodevelopmental origins via midbrain-hindbrain hypoplasia
    Zhiyi Xia, Hui LIU, Pengbo Guo, Chongfen Chen, Lili Ge, Longfei Tang, Yaodong Zhang, Yanli Ma · 2026 · Human Genetics and Genomics Advances
50. The Geminiviral Effector AC4 Suppresses Nonsense‐Mediated mRNA Decay Via Upf1 Degradation
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51. The prospects of targeting messenger RNA surveillance factor PELOTA for developing virus resistance in plants
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52. Translational control of Toxoplasma gondii differentiation
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53. Genetic encoding of multiple distinct noncanonical amino acids
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54. The Role of Nonsense-mediated mRNA Decay in Aging
    Eunseok Kang, Hyunwoo C. Kwon, Seung‐Jae Lee · 2026 · Journal of Molecular Biology
55. High-Resolution Profiling of NMD Targets in Yeast
    Feng He, Alper Celik, Richard Baker, Allan Jacobson · 2018 · Methods in enzymology on CD-ROM/Methods in enzymology
56. AtSIEK, an EXD1-like protein with KH domain, involves in salt stress response by interacting with FRY2/CPL1
    Xiangxiang Zhang, Qinyu Xie, Lijun Xiang, Zhonghua Lei, Qixiu Huang, Juncheng Zhang, Maohong Cai, Tao Chen · 2023 · International Journal of Biological Macromolecules
57. Intermolecular base‐pairing interactions, a unique topology and exoribonuclease‐resistant noncoding RNAs drive formation of viral chimeric RNAs in plants
    Katalin Nemes, Jose Fernando Gil, Sebastian Liebe, Mansi Mansi, Efstratia Poimenopoulou, Britt‐Louise Lennefors, Mark Varrelmann, Eugene I. Savenkov · 2023 · New Phytologist
58. Characterization of the mIF4G Domains in the RNA Surveillance Protein Upf2p
    Edgardo M. Colón, Luis A. Haddock, Clarivel Lasalde, Qishan Lin, Juan S. Ramírez-Lugo, Carlos Ivan Gonzalez · 2023 · Current Issues in Molecular Biology
59. Nonsense-mediated mRNA decay factors target short poly(A)-tailed mRNAs lacking a premature termination codon
    Toni Gouhier, Cosmin Saveanu, Gwenaël Badis · 2026 · Nature Communications
60. Alternative Splicing Regulation of Cancer-Related Pathways inCaenorhabditis elegans: An In Vivo Model System with a Powerful Reverse Genetics Toolbox
    Sergio Barberán-Soler, James Matthew Ragle · 2013 · International Journal of Cell Biology
61. Mutation Screening of the GLE1 Gene in a Large Chinese Cohort of Amyotrophic Lateral Sclerosis Patients
    Yanran Li, Bo Sun, Zhanjun Wang, Zhengqing He, Fei Yang, Hongfen Wang, Fang Cui, Zhaohui Chen, Ling Li, Chaodong Wang et al. · 2021 · Frontiers in Neuroscience
62. A novel mutation of the NF1 gene in a Chinese family with neurofibromatosis type 1.
    Qi He, Jingjing Jiang, Yang Jiao, Junjie Zeng, Huan Zhang, Zhengzhong Zhang · 2022 · PubMed Central
63. Reply: A homozygous GDAP2 loss-of-function variant in a patient with adult-onset cerebellar ataxia; and Novel GDAP2 pathogenic variants cause autosomal recessive spinocerebellar ataxia-27 (SCAR27) in a Chinese family
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64. Transcription | Messenger RNA Processing in Eukaryotes
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65. A novel regulatory pathway recognizes and degrades transcripts with long 3′ untranslated regions
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66. RBM8A promotes gastric cancer progression by binding with UPF3B to induce BBC3 mRNA degradation
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67. KRAS-ERK signaling drives metastasis in colorectal cancer via phosphorylation-dependent activation of the ZBTB20-TGFBR2 axis
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68. A Comprehensive Review of the Ubiquitin-Proteasome System in Synapse Remodeling and Neurodegenerative Diseases
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69. Transcriptom Analysis of Auricularia auriculla-judae Fruit Body Treated with Gamma Radiation on Mycelium
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70. Splicing regulation and intron evolution in the short-intron ciliate model of endosymbiosis Paramecium bursaria
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71. SMAD5 as a novel susceptibility gene for congenital patent ductus arteriosus
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72. Protein Mis-Termination Initiates Genetic Diseases, Cancers, and Restricts Bacterial Genome Expansion
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73. Crucial role of ATP-bound Sse1 in Upf1-dependent degradation of the truncated product
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74. Regulation of Arp5 expression by alternative splicing coupled to nonsense-mediated RNA decay
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75. Where To Stop: Occurrence and Evolution of Translational Recoding Signals in RNA Viruses of Eukaryotes
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76. Synergistic Methods to Investigate Eukaryotic Translation and Its Quality Control
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77. General Aspects Related to Nonsense Mutations
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78. Advances in small protein identification
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79. Computational Methods and Approaches in Pharmacogenomic Research
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80. Cytoplasmic mRNA Surveillance Pathways
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81. Estudo da Beta-catenina em tumores adrenocorticais humanos
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82. Targeted mRNA Degradation
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83. Towards Synthesis of Simplified Analogues of Pateamine A
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84. Poly(A) tail length regulation by mRNA deadenylases is critical for suppression of transposable elements
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85. mRNA N1-2’O-methylation by CMTR1 affects NVL2 mRNA splicing
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86. Targeted Perturb-seq Reveals EGR1 and FOS as Key Regulators of the Transcriptional RAF-MAPK Response
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87. Transcriptional Regulation in Algae, Fungi and Plants: Mating Loci, Splicing, and miRNAs
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88. Yeast Upf1 Associates With RibosomesTranslating mRNA Coding Sequences Upstream of Normal Termination Codons: A Dissertation
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89. Transcription et épissage des gènes d’immunoglobulines non-productifs : étude des mécanismes mis en jeu et de leur influence au cours du développement des lymphocytes B
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90. Aspergillus nidulans Upf1: putative role of conserved active sites in ribosome recycling and 3' end mRNA tagging
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91. A novel 1‐bp deletion mutation of the EDA gene in a Chinese Han family with X‐linked hypohidrotic ectodermal dysplasia
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92. Post-transcriptional regulation of inflammatory mRNA by Regnase-1 and Roquin
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93. The Role of UPF Proteins in Nonsense-Mediated Decay and in Neurogenesis
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94. NMR study of eukaryotic translation termination
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95. Regulation of pre-mRNA splicing and mRNA degradation in Saccharomyces cerevisiae
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96. Long-read sequencing of nascent RNA reveals coupling among RNA processing events
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97. Statins and Protein Prenylation in the Retina
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98. Recent Advances in Virus-host Coevolution and Protective Mechanisms against Plant Viruses
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99. Investigação genético-molecular em pacientes com alta estatura
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100. Caracterización de la función de SRSF4 en la homeostasis del corazón
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