The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors
Open accessAbstract
Staphylococcus aureus is a major bacterial pathogen that causes disease worldwide. The emergence of strains that are resistant to commonly used antibiotics and the failure of vaccine development have resulted in a renewed interest in the pathophysiology of this bacterium. Staphylococcal leukocidins are a family of bi-component pore-forming toxins that are important virulence factors. During the past five years, cellular receptors have been identified for all of the bi-component leukocidins. The identification of the leukocidin receptors explains the cellular tropism and species specificity that is exhibited by these toxins, which has important biological consequences. In this Review, we summarize the recent discoveries that have reignited interest in these toxins and provide an outlook for future research.
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Cites
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Cited by
Skeletal infections: microbial pathogenesis, immunity and clinical management
Masters, E. A., Ricciardi, B. F., Bentley, K. L. D. M., Moriarty, T. F., Schwarz, E. M., & Muthukrishnan, G. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00686-0 · Cited by 735
Staphylococcus aureus host interactions and adaptation
Howden, B. P., Giulieri, S. G., Wong Fok Lung, T., Baines, S. L., Sharkey, L. K., Lee, J. Y. H., Hachani, A., Monk, I. R., & Stinear, T. P. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-023-00852-y · Cited by 689
Staphylococcus aureus Secreted Toxins and Extracellular Enzymes
Tam, K., & Torres, V. J. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0039-2018 · Cited by 452
Self-citationStaphylococcus aureus in Animals
Haag, A. F., Fitzgerald, J. R., & Penadés, J. R. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0060-2019 · Cited by 257
Savin, A., Anderson, E. E., Dyzenhaus, S., Podkowik, M., Shopsin, B., Pironti, A., & Torres, V. J. (2024) · Infection and Immunity · doi:10.1128/iai.00526-23 · Cited by 9
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Metadata
- Authors
- Spaan, A. N., van Strijp, J. A. G., & Torres, V. J.
- Venue
- Nature Reviews Microbiology
- Published
- 2017-04-19
- Volume
- 15
- Issue
- 7
- Pages
- 435-447
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2607187374
- Cited by
- 347
- References
- 24
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- bronze
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