The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
At the centre: influenza A virus ribonucleoproteins
Open accessAbstract
Influenza A viral ribonucleoprotein (vRNP) complexes comprise the eight genomic negative-sense RNAs, each of which is bound to multiple copies of the vRNP and a trimeric viral polymerase complex. The influenza virus life cycle centres on the vRNPs, which in turn rely on host cellular processes to carry out functions that are necessary for the successful completion of the virus life cycle. In this Review, we discuss our current knowledge about vRNP trafficking within host cells and the function of these complexes in the context of the virus life cycle, highlighting how structure contributes to function and the crucial interactions with host cell pathways, as well as on the information gaps that remain. An improved understanding of how vRNPs use host cell pathways is essential to identify mechanisms of virus pathogenicity, host adaptation and, ultimately, new targets for antiviral intervention.
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Cites
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility
VALE, R., REESE, T., & SHEETZ, M. (1985) · Cell · doi:10.1016/s0092-8674(85)80099-4 · Cited by 1,993
Cellular Proteins in Influenza Virus Particles
Shaw, M. L., Stone, K. L., Colangelo, C. M., Gulcicek, E. E., & Palese, P. (2008) · PLoS Pathogens · doi:10.1371/journal.ppat.1000085 · Cited by 324
Mapping the Phosphoproteome of Influenza A and B Viruses by Mass Spectrometry
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Cited by
Host and viral determinants of influenza A virus species specificity
Long, J. S., Mistry, B., Haslam, S. M., & Barclay, W. S. (2019) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0115-z · Cited by 667
Species difference in ANP32A underlies influenza A virus polymerase host restriction
Long, J. S., Giotis, E. S., Moncorgé, O., Frise, R., Mistry, B., James, J., Morisson, M., Iqbal, M., Vignal, A., Skinner, M. A., et al. (2016) · Nature · doi:10.1038/nature16474 · Cited by 323
Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis
Maelfait, J., Liverpool, L., Bridgeman, A., Ragan, K. B., Upton, J. W., & Rehwinkel, J. (2017) · The EMBO Journal · doi:10.15252/embj.201796476 · Cited by 237
Mechanism of Virus Attenuation by Codon Pair Deoptimization
Groenke, N., Trimpert, J., Merz, S., Conradie, A. M., Wyler, E., Zhang, H., Hazapis, O.-G., Rausch, S., Landthaler, M., Osterrieder, N., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107586 · Cited by 85
“All genomic RNA segments of IAV contain cis-acting signals at their termini, which are essential for the packaging of viral RNA (vRNA) segments into virions (Eisfeld et al., 2015).”
Background
Metadata
- Authors
- Eisfeld, A. J., Neumann, G., & Kawaoka, Y.
- Venue
- Nature Reviews Microbiology
- Published
- 2014-11-24
- Volume
- 13
- Issue
- 1
- Pages
- 28-41
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W1963710267
- Cited by
- 476
- References
- 3
- FWCI
- 4.34
- Type
- journal article
- Language
- en
- Open access
- green
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