The DOI matches its Crossref record; 98 of the 98 references it cites were found in a registry or an index.
STEC-HUS, atypical HUS and TTP are all diseases of complement activation
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Complement: a key system for immune surveillance and homeostasis
Ricklin, D., Hajishengallis, G., Yang, K., & Lambris, J. D. (2010) · Nature Immunology · doi:10.1038/ni.1923 · Cited by 3,654
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
Tarr, P. I., Gordon, C. A., & Chandler, W. L. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71144-2 · Cited by 1,774
Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura
Tsai, H.-M., & Lian, E. C.-Y. (1998) · New England Journal of Medicine · doi:10.1056/nejm199811263392203 · Cited by 1,760
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
Levy, G. G., Nichols, W. C., Lian, E. C., Foroud, T., McClintick, J. N., McGee, B. M., Yang, A. Y., Siemieniak, D. R., Stark, K. R., Gruppo, R., et al. (2001) · Nature · doi:10.1038/35097008 · Cited by 1,749
Furlan, M., Robles, R., Galbusera, M., Remuzzi, G., Kyrle, P. A., Brenner, B., Krause, M., Scharrer, I., Aumann, V., Mittler, U., et al. (1998) · New England Journal of Medicine · doi:10.1056/nejm199811263392202 · Cited by 1,657
Self-citationKarmali, M. A., Petric, M., Lim, C., Fleming, P. C., Arbus, G. S., & Lior, H. (1985) · Journal of Infectious Diseases · doi:10.1093/infdis/151.5.775 · Cited by 1,388
Atypical Hemolytic–Uremic Syndrome
Noris, M., & Remuzzi, G. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0902814 · Cited by 1,338
Self-citationEpidemic Profile of Shiga-Toxin–Producing Escherichia coli O104:H4 Outbreak in Germany
Frank, C., Werber, D., Cramer, J. P., Askar, M., Faber, M., an der Heiden, M., Bernard, H., Fruth, A., Prager, R., Spode, A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1106483 · Cited by 1,139
Noris, M., Caprioli, J., Bresin, E., Mossali, C., Pianetti, G., Gamba, S., Daina, E., Fenili, C., Castelletti, F., Sorosina, A., et al. (2010) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.02210310 · Cited by 1,042
Self-citationGeneration of C5a in the absence of C3: a new complement activation pathway
Huber-Lang, M., Sarma, J. V., Zetoune, F. S., Rittirsch, D., Neff, T. A., McGuire, S. R., Lambris, J. D., Warner, R. L., Flierl, M. A., Hoesel, L. M., et al. (2006) · Nature Medicine · doi:10.1038/nm1419 · Cited by 975
Cited by
Overview of complement activation and regulation
Noris, M., & Remuzzi, G. (2013) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2013.08.001 · Cited by 864
Self-citationThe immune system and kidney disease: basic concepts and clinical implications
Kurts, C., Panzer, U., Anders, H.-J., & Rees, A. J. (2013) · Nature Reviews Immunology · doi:10.1038/nri3523 · Cited by 696
Complement component C3 – The “Swiss Army Knife” of innate immunity and host defense
Ricklin, D., Reis, E. S., Mastellos, D. C., Gros, P., & Lambris, J. D. (2016) · Immunological Reviews · doi:10.1111/imr.12500 · Cited by 484
Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms
Ricklin, D., & Lambris, J. D. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1203487 · Cited by 478
Complement, a target for therapy in inflammatory and degenerative diseases
Morgan, B. P., & Harris, C. L. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4657 · Cited by 431
Metadata
- Authors
- Noris, M., Mescia, F., & Remuzzi, G.
- Venue
- Nature Reviews Nephrology
- Published
- 2012-09-18
- Volume
- 8
- Issue
- 11
- Pages
- 622-633
- ISSN
- 1745-8323 (ISSN-L)
- 1759-5061
- 1759-507X
- OpenAlex
- W2038181025
- Cited by
- 383
- References
- 98
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: STEC-HUS, atypical HUS and TTP are all diseases of complement activation. https://app.cochat.ai/papers/10.1038/nrneph.2012.195
- The paper
- Noris, M., Mescia, F., & Remuzzi, G. (2012). STEC-HUS, atypical HUS and TTP are all diseases of complement activation. Nature Reviews Nephrology. https://doi.org/10.1038/nrneph.2012.195
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
