Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

Kon, Takahide, Imamula, Kenji, Roberts, Anthony J, Ohkura, Reiko, Knight, Peter J, Gibbons, I R, Burgess, Stan A, Sutoh, Kazuo·2009·Nature Structural & Molecular Biology
DOI 10.1038/nsmb.1555

Cited by (169)

Items 101–169 of 169

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  2. Multiple Roles, Multiple Adaptors: Dynein During Cell Cycle
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  3. Long-range electrostatic interactions significantly modulate the affinity of dynein for microtubules
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  4. How Does a Registry Change in Dynein’s Coiled-Coil Stalk Drive Binding of Dynein to Microtubules?
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  5. Pac1/LIS1 promotes an uninhibited conformation of dynein that coordinates its localization and activity
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  6. Tetramer formation by the caspase‐activated fragment of the Par‐4 tumor suppressor
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  7. Structure of dynein-dynactin on microtubules shows tandem recruitment of cargo adaptors
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  8. A nucleotide code governs Lis1’s ability to relieve dynein autoinhibition
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  10. Minimum requirements for motility of a processive motor protein
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  11. Dictyostelium discoideum
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  12. Discovery of Dynein and its Properties
    I. R. Gibbons · 2011 · Elsevier eBooks
  13. Dynein dynamics
    Peter Höök, Richard B. Vallee · 2012 · Nature Structural & Molecular Biology
  14. The Role of Dynactin in Dynein-Mediated Motility
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  15. Microtubule binding-induced allostery promotes LIS1 dissociation from dynein prior to cargo transport
    William D. Ton, Yue Wang, Pengxin Chai, Cissloyny Beauchamp-Perez, Nicholas T. Flint, Lindsay G. Lammers, Hao Xiong, Kai Zhang, Steven M. Markus · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  16. The mechanism and energetics of the dynein priming stroke
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  17. Identification and Characterization of Dynein Genes in Tetrahymena
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  18. Electron Microscopic Imaging and Analysis of Isolated Dynein Particles
    Anthony J. Roberts, Stan A. Burgess · 2009 · Methods in cell biology
  19. Cryo-EM Reveals the Mechanochemical Cycle of Reactive Full-length Human Dynein-1
    Pengxin Chai, Jun Yang, Indigo C. Geohring, Steven M. Markus, Yue Wang, Kai Zhang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Stepping dynamics of dynein characterized by MINFLUX
    Joseph D. Slivka, Emma S. Gleave, Mert Golcuk, Devinda P. Wijewardena, John T. Canty, Paul R. Selvin, Mert Gür, Andrew P. Carter, Ahmet Yıldız · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Crystal structure of the stalk region of axonemal inner‐arm dynein‐d reveals unique features in the coiled‐coil and microtubule‐binding domain
    Seolmin Ko, Akiyuki Toda, Hideaki Tanaka, Jian Yu, Genji Kurisu · 2023 · FEBS Letters
  22. The Mechanical Components of the Dynein Motor
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  23. The microtubule-associated protein She1 coordinates directional spindle positioning by spatially restricting dynein activity
    Kari H. Ecklund, Megan E. Bailey, Kelly A. Kossen, Carsten K. Dietvorst, Charles L. Asbury, Steven M. Markus · 2021 · Journal of Cell Science
  24. Structural atlas of dynein motors at atomic resolution
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  25. Discovery of dynein and its properties
    I. R. Gibbons · 2017 · Elsevier eBooks
  26. 4.19 Cytoplasmic Dynein: Its ATPase Cycle and ATPase-dependent Structural Changes
    Takahide Kon, Tomohiro Shima, K. Sutoh · 2012 · Elsevier eBooks
  27. A model for the chemomechanical coupling of the mammalian cytoplasmic dynein molecular motor
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  28. Assessment of the Topology and Oligomerisation States of Coiled Coils Using Metadynamics with Conformational Restraints
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  29. Dynein Motor Mechanisms
    Michael P. Koonce, Irina Tikhonenko · 2011 · Elsevier eBooks
  30. The new biology of cilia: Review and annotation of a symposium
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  31. Chain Sliding versus β‐Sheet Formation upon Shearing Single α‐Helical Coiled Coils
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  32. Effects of iodide on the coupling between ATP hydrolysis and motile activity in axonemal dynein
    Izumi Nakano, Rin Fujiwara, Mikiyo Wada, Chikako Shingyoji · 2011 · Cytoskeleton
  33. Mechanism and regulation of dynein motors
    Helgo Schmidt, Andrew P. Carter · 2017 · Elsevier eBooks
  34. Comparative structural study on axonemal and cytoplasmic dyneins
    Noemi Zimmermann, Takashi Ishikawa · 2024 · Cytoskeleton
  35. Processivity vs. Beating: Comparing Cytoplasmic and Axonemal Dynein Microtubule Binding Domain Association with Microtubule
    Nayere Tajielyato, Emil G Alexov · 2019 · International Journal of Molecular Sciences
  36. Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain
    Toshiki Yagi, Akiyuki Toda, Muneyoshi Ichikawa, Genji Kurisu · 2023 · Biophysics and Physicobiology
  37. Modeling of Chemomechanical Coupling of Cytoplasmic Dynein Motors
    Ping Xie · 2024 · The Journal of Physical Chemistry B
  38. Stopped in its tracks: Negative regulation of the dynein motor by the yeast protein She1
    Jeffrey K. Moore · 2013 · BioEssays
  39. Dynein struts its stuff
    Neil Billington, James R. Sellers · 2011 · Nature Structural & Molecular Biology
  40. Mg2+‐free ATP regulates the processivity of native cytoplasmic dynein
    Vincent A. Behrens, Wilhelm J. Walter, Carsten Peters, Tianbang Wang, Bernhard Brenner, Michael A. Geeves, Tim Scholz, Walter Steffen · 2018 · FEBS Letters
  41. Organization of Dyneins in the Axoneme
    Takashi Ishikawa · 2011 · Elsevier eBooks
  42. The AAA+ Powerhouse – Trying to Understand How it Works
    Paul A. Tucker · 2011 · Elsevier eBooks
  43. High accuracy measurements of nanometer-scale distances between fluorophores at the single-molecule level
    Stefan Niekamp, Jongmin Sung, Walter Huynh, Gira Bhabha, Ronald D. Vale, Nico Stuurman · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Bicaudal D acts as a sensor to enable dynein-kinesin co-dependence
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  45. Non-Processive Force Generation by Mammalian Axonemal Dynein In Situ on Doublet Microtubules
    David P. Lorch, Kathleen A. Lesich, Charles B. Lindemann, Alan J. Hunt · 2013 · Cellular and Molecular Bioengineering
  46. Studying Dynein Mechanochemistry with an Optical Trap
    Emre Kusakci, Ahmet Yıldız · 2023 · Methods in molecular biology
  47. Backbone and side-chain 1H, 15N and 13C resonance assignments of the microtubule-binding domain of yeast cytoplasmic dynein in the high and low-affinity states
    Osamu Takarada, N. Nishida, Masahide Kikkawa, Ichio Shimada · 2013 · Biomolecular NMR Assignments
  48. Mapping genotype-phenotype associations of nsSNPs in coiled-coil oligomerization domains of the human proteome
    Kaavya A Mohanasundaram, Mani P Grover, Tamsyn M. Crowley, Andrzej M Goscinski, Merridee A. Wouters · 2017 · Human Mutation
  49. Single-molecule dynein motor mechanics in vitro
    Ahmet Yıldız · 2017 · Elsevier eBooks
  50. Dyneins
    Caroline A Cypranowska, Ahmet Yıldız, Takashi Ishikawa · 2015 · Elsevier eBooks
  51. Dyneins
    Ahmet Yıldız, Takashi Ishikawa · 2022 · Elsevier eBooks
  52. Kristallographische Untersuchungen zur Schweren Kette von Dynein und dem Capping-Protein Cap32/34
    Christian Eckert · 2012
  53. KIF1A: a candidate motor protein for dense-core vesicle transport in cultured hippocampal neurons
    Anastasia Kuzmin · 2009 · Summit (Simon Fraser University)
  54. Structural and Functional Modularity of Cytoplasmic Dynein
    Tomohiro Shima, Kazuo Sutoh, Takahide Kon · 2011 · Seibutsu Butsuri
  55. Atomistic analysis of ATP hydrolysis effect on a dynein walking mechanism
    Soojin Jo, Min Hyeok Kim, Jae Boong Choi, Moon Ki Kim · 2016 · Journal of Mechanical Science and Technology
  56. The Mechanism of Processivity and Directionality of Cytoplasmic Dynein
    Frank B. Cleary · 2014 · eScholarship (California Digital Library)
  57. Ian Read Gibbons. 30 October 1931—30 January 2018
    Wendy Gibbons, Ronald D. Vale, Winfield S. Sale · 2019 · Biographical Memoirs of Fellows of the Royal Society
  58. Mechanisms of Regulation of Cytoplasmic Dynein
    Zaw Min Htet · 2019 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  59. The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein
    Xinglei Liu, Lu Rao, Arne Gennerich · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  60. Thermal fluctuations assist mechanical signal propagation in coiled-coil proteins
    Judit Clopés, Jaeoh Shin, Marcus Jahnel, Stephan W. Grill, Vasily Zaburdaev · 2021 · Physical review. E
  61. Dynein Motility: Mechanism
    Kazuhiro Oiwa · 2020 · Springer eBooks
  62. Dynein Motility: Mechanism
    Kazuhiro Oiwa · 2012 · Springer eBooks
  63. Proteasomal ATPases Hard at Work: The Inner Workings of a Protein Destruction Machine.
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  64. Programmable Nanomachines That Move on DNA Nanotube Tracks
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  65. Assessment of the Topology and OligomerisationStates of Coiled Coils Using Metadynamics withConformational Restraints
    Evangelia Notari, Christopher W. Wood, Julien Michel · 2024 · ChemRxiv
  66. Structural studies of the cytoplasmic dyneins and the BicD2 cargo adaptor
    Robert Fagiewicz · 2022
  67. Structural and ensemble-based mechanistic insights into cytoplasmic dynein-1
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  68. ADP-Bound States of Cytoplasmic Dynein: Cryo-electron Microscopy Reveals a Two-Step Post-Power-Stroke Transition and Roles of Regulatory ATPase Sites
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  69. Characterizing dynamics of productive dynein stepping by MINFLUX
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