Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

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Items 301–400 of 522

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12. NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination
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15. PRPF8 is important for BRCA1-mediated homologous recombination
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16. Unraveling the nexus: Genomic instability and metabolism in cancer
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17. Histone lysine modifying enzymes and their critical roles in DNA double-strand break repair
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18. The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells
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19. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168
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24. Conversations between chromatin modifications and DNA double strand break repair: A commentary
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26. Targeted Cancer Therapy Based on Acetylation and Deacetylation of Key Proteins Involved in Double-Strand Break Repair
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27. CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers
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30. Heterogeneity of DNA damage incidence and repair in different chromatin contexts
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31. New insights into the DNA repair pathway choice with NuA4/TIP60
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32. Chromatin Ubiquitination Guides DNA Double Strand Break Signaling and Repair
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33. Recruitment of lysine demethylase 2A to DNA double strand breaks and its interaction with 53BP1 ensures genome stability
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34. Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair
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35. Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening
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36. Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites
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38. Mechanisms of Histone Modifications
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41. Enhancing Precision and Efficiency of Cas9-Mediated Knockin Through Combinatorial Fusions of DNA Repair Proteins
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43. RNF8‐ubiquitinated KMT5A is required for RNF168‐induced H2A ubiquitination in response to DNA damage
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44. The regulation of DNA end resection by chromatin response to DNA double strand breaks
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46. A field guide to the proteomics of post‐translational modifications in DNA repair
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47. Assembling a protective shield
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48. Age-associated deficient recruitment of 53BP1 in G1 cells directs DNA double-strand break repair to BRCA1/CtIP-mediated DNA-end resection
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49. Communication between chromatin and homologous recombination
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50. H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci
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55. Perfecting DNA double-strand break repair on transcribed chromatin
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56. Evaluating the Genomic Parameters Governing rAAV-Mediated Homologous Recombination
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57. Chromatin regulators and their impact on DNA repair and G2 checkpoint recovery
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58. New facets in the chromatin-based regulation of genome maintenance
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59. Histone deacetylase 9 modulates the acetylation dynamics of phototropin 1 to fine-tune phototropic responses in plants
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60. The Role of Posttranslational Modifications in DNA Repair
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61. Mechanisms of Histone Modifications
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63. DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells
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64. Multifaceted Influence of Histone Deacetylases on DNA Damage Repair: Implications for Hepatocellular Carcinoma
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65. RNA methylation, homologous recombination repair and therapeutic resistance
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66. Seeing Is Believing: Visualizing Transcriptional Dynamics in Single Cells
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67. Proteomic analysis of H3K36me3 and PSIP1/p75 (LEDGF) complexes reveal their wider role in DNA repair
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68. Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells
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69. Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress
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