SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

Cited by (302)

Items 101–200 of 302

1. JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies
   Charlotte E. J. Downes, Barbara J. McClure, Daniel P. McDougal, Susan L. Heatley, John B. Bruning, Danièl Thomas, David T. O. Yeung, Deborah L. White · 2022 · Frontiers in Cell and Developmental Biology
2. SOCS1: Regulator of T Cells in Autoimmunity and Cancer
   Subburaj Ilangumaran, Diwakar Bobbala, Sheela Ramanathan · 2017 · Current topics in microbiology and immunology
3. SOCS1 and its Potential Clinical Role in Tumor
   Jie Ying, Xiaoyan Qiu, Lu Yu, Miaomiao Zhang · 2019 · Pathology & Oncology Research
4. Interleukin 11 (IL-11): Role(s) in Breast Cancer Bone Metastases
   Paola Maroni, Paola Bendinelli, Anita Ferraretto, Giovanni Lombardi · 2021 · Biomedicines
5. SOCS: negative regulators of cytokine signaling for immune tolerance
   Akihiko Yoshimura, Minako Ito, Setsuko Mise‐Omata, Makoto Ando · 2021 · International Immunology
6. Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression
   Jamie J.L. Williams, Kirsten MA Munro, Timothy M. Palmer · 2014 · Cells
7. Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
   Williams, Jamie J. L., Alotaiq, Nasser, Mullen, William, Burchmore, Richard, Liu, Libin, Baillie, George S., Schaper, Fred, Pilch, Paul F., Palmer, Timothy M. · 2018 · Nature Communications
8. Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
   Takashi Ushiki, Nicholas D. Huntington, Stefan P. Glaser, Hiu Kiu, Angela Georgiou, Jian‐Guo Zhang, Donald Metcalf, Nicos Anthony Nicola, Andrew Warwick Roberts, Warren S. Alexander · 2016 · PLoS ONE
9. Exploiting the STAT3 Nexus in Cancer-Associated Fibroblasts to Improve Cancer Therapy
   Amr H. Allam, Marina H. Yakou, Lokman Pang, Matthias Ernst, Jennifer Huynh · 2021 · Frontiers in Immunology
10. Making sense of IL‐6 signalling cues in pathophysiology
    David Millrine, Robert L. Jenkins, Stuart T. O. Hughes, Simon A. Jones · 2021 · FEBS Letters
11. Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling
    Ahmed M. Atwa, Omnia A. M. Abd El‐Ghafar, Emad H. M. Hassanein, Somya E. Mahdi, Ghadir A. Sayed, Reem Saleh Alruhaimi, Haifa Ali Alqhtani, Mohammed Alotaibi, Ayman Moawad Mahmoud · 2022 · Pharmaceuticals
12. SOCS-mediated immunomodulation of natural killer cells
    Narelle Keating, Sandra E. Nicholson · 2018 · Cytokine
13. Endocrine and cellular physiology and pathology of the insulin-like growth factor acid-labile subunit
    Robert C. Baxter · 2024 · Nature Reviews Endocrinology
14. Crosstalk between CXCL12/CXCR4/ACKR3 and the STAT3 Pathway
    Zelong Ma, Faxiao Zhou, Hua Jin, Xiaoming Wu · 2024 · Cells
15. Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses
    Leila N. Varghese, Daniela Ungureanu, Nicholas P. D. Liau, Samuel N. Young, Artem Laktyushin, Henrik M. Hammarén, Isabelle S. Lucet, Nicos Anthony Nicola, Olli Silvennoinen, Jeffrey J. Babon et al. · 2013 · Biochemical Journal
16. The Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia
    Bernhard Moser, Sophie Edtmayer, Agnieszka Witalisz‐Siepracka, Dagmar Stoiber · 2021 · Biomedicines
17. Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3)
    Elisabeth Maier, Michaela Mittermeir, Stefanie Ess, Theresa Neuper, Angela Schmiedlechner, Albert Duschl, Jutta Horejs‐Hoeck · 2015 · Journal of Biological Chemistry
18. Role of STAT3 Transcription Factor in Pathogenesis of Bronchial Asthma
    Никольский Александр Аркадьевич, Igor P. Shilovskiy, E.D. Barvinskaia, Корнеев Артем Викторович, M. S. Sundukova, Musa Rakhimovich Khaitov · 2021 · Biochemistry (Moscow)
19. Inflammatory Skin Diseases: Focus on the Role of Suppressors of Cytokine Signaling (SOCS) Proteins
    Antonia Cianciulli, Rosa Calvello, Chiara Porro, Dario Domenico Lofrumento, Maria Antonietta Panaro · 2024 · Cells
20. The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration
    Kelan Chen, Peter E. Czabotar, Marnie E. Blewitt, James M. Murphy · 2016 · Biochemical Journal
21. Orchestration of signaling by structural disorder in class 1 cytokine receptors
    Pernille Seiffert, Katrine Bugge, Mads Mørup Nygaard, Gitte W. Haxholm, Jacob H. Martinsen, Martin Nors Pedersen, Lise Arleth, Wouter Boomsma, Birthe Brandt Kragelund · 2020 · Cell Communication and Signaling
22. SOCS3 Promotes ALV-J Virus Replication via Inhibiting JAK2/STAT3 Phosphorylation During Infection
    Guodong Mo, Huali Fu, Bowen Hu, Qihong Zhang, Mingjian Xian, Zihao Zhang, Ling Lin, Meiqing Shi, Qinghua Nie, Xiquan Zhang · 2021 · Frontiers in Cellular and Infection Microbiology
23. Benzo[a]pyrene stimulates miR-650 expression to promote the pathogenesis of fatty liver disease and hepatocellular carcinoma via SOCS3/JAK/STAT3 cascades
    Yang Ge, Pengfei Gu, Wenbo Wang, Liyuan Cao, Lulu Zhang, Jingquan Li, Wei Mu, Hui Wang · 2021 · Journal of Molecular Cell Biology
24. The role of proteolysis in interleukin-11 signaling
    Juliane Lokau, Birte Kespohl, Sophia Kirschke, Christoph Garbers · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
25. Proteomimetics of Natural Regulators of JAK–STAT Pathway: Novel Therapeutic Perspectives
    Sara La Manna, Ilaria De Benedictis, Daniela Marasco · 2022 · Frontiers in Molecular Biosciences
26. Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib
    Sobotta, Svantje, Raue, Andreas, Huang, Xiaoyun, Vanlier, Joep, Jünger, Anja, Bohl, Sebastian, Albrecht, Ute, Hahnel, Maximilian J., Wolf, Stephanie, Mueller, Nikola S. et al. · 2017 · Frontiers in Physiology
27. Transcriptional control of interferon-stimulated genes
    Olga Babadei, Birgit Strobl, Mathias M. Müller, Thomas Decker · 2024 · Journal of Biological Chemistry
28. An altered peripheral IL6 response in major depressive disorder
    Kelli M. Money, Zita Galik-Olah, Željka Korade, Krassimira A. Garbett, Richard Charles Shelton, Károly Mirnics · 2016 · Neurobiology of Disease
29. SOCS3 inhibits the pathological effects of IL-22 in non-melanoma skin tumor-derived keratinocytes
    Stefania Madonna, Claudia Scarponi, Martina Morelli, Rosanna Sestito, Pasqualina Liana Scognamiglio, Daniela Marasco, Cristina Albanesi · 2017 · Oncotarget
30. Ferulic acid protects against gamma-radiation induced liver injury via regulating JAK/STAT/Nrf2 pathways
    Rania A. Gawish, Esraa M. Samy, Maha M. Aziz · 2024 · Archives of Biochemistry and Biophysics
31. Persistence of myelofibrosis treated with ruxolitinib: biology and clinical implications
    David M. Ross, Jeffrey J. Babon, Denis Tvorogov, Danièl Thomas · 2021 · Haematologica
32. The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer
    Cécile Naudin, Clément Chevalier, Serge Roche · 2016 · Oncotarget
33. Chimeric Peptidomimetics of SOCS 3 Able to Interact with JAK2 as Anti-inflammatory Compounds
    Sara La Manna, Laura Lopez‐Sanz, Flavia Anna Mercurio, Sara Fortuna, Marilisa Leone, Carmen Gómez‐Guerrero, Daniela Marasco · 2020 · ACS Medicinal Chemistry Letters
34. Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands
    Edmond M. Linossi, Kunlun Li, Gianluca Veggiani, Cyrus Tan, Farhad Dehkhoda, Colin Hockings, Dale J. Calleja, Narelle Keating, Rebecca Feltham, Andrew J. Brooks et al. · 2021 · Nature Communications
35. Dysregulation of the suppressor of cytokine signalling 3–signal transducer and activator of transcription-3 pathway in the aetiopathogenesis of Sjögren's syndrome
    Sonia R. Vartoukian, Wanninayaka Mudiyanselage Tilakaratne, Noha Seoudi, M Bombardieri, Lesley A. Bergmeier, Anwar R. Tappuni, Farida Fortune · 2014 · Clinical & Experimental Immunology
36. Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation
    Yuchen Nan, Chunyan Wu, Yan‐Jin Zhang · 2018 · Viruses
37. Recent advances in anti-inflammatory active components and action mechanisms of natural medicines
    Zhimin Wu, Tao Zhang, Xiaofei Ma, Shuai Guo, Qingqing Zhou, Arshad Zahoor, Ganzhen Deng · 2023 · Inflammopharmacology
38. MiR-125a Is a critical modulator for neutrophil development
    Yuting Qin, Lingling Wu, Ye Ouyang, Ping Zhou, Haibo Zhou, Yan Wang, Jianyang Ma, Jinsong Zhang, Yanan Chen, Jie Qian et al. · 2017 · PLoS Genetics
39. The Absence of GH Signaling Affects the Susceptibility to High-Fat Diet-Induced Hypothalamic Inflammation in Male Mice
    Eva Baquedano, Ana M. Ruiz‐Lopez, Elahu Gosney Sustarsic, J. Herpy, Edward Owen List, Julie Ann Chowen, Laura M. Frago, John Joseph Kopchick, Jesús Argente · 2014 · Endocrinology
40. Unravelling the druggability and immunological roles of the SOCS-family proteins
    Dylan M. Lynch, Beth Forrester, Thomas Webb, Alessio Ciulli · 2024 · Frontiers in Immunology
41. Signaling pathways in induced naïve pluripotency
    Shoudong Ye, Dahai Liu, Qi‐Long Ying · 2014 · Current Opinion in Genetics & Development
42. miR-181a is a novel player in the STAT3-mediated survival network of TCRαβ+ CD8+ T large granular lymphocyte leukemia
    Jorn L. J. C. Assmann, Leticia G. León, Christiaan J. Stavast, Sanne E. van den Bogaerdt, Joyce Schilperoord‐Vermeulen, Yorick Sandberg, Mar Bellido, Stefan J. Erkeland, David J. Feith, Thomas P. Loughran et al. · 2021 · Leukemia
43. Exosome-mediated miR-9-5p promotes proliferation and migration of renal cancer cells both in vitro and in vivo by targeting SOCS4
    Wenbin Song, Yule Chen, Guodong Zhu, Hongjun Xie, Zhishang Yang, Lei Li · 2020 · Biochemical and Biophysical Research Communications
44. Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5
    Indu R. Chandrashekaran, Biswaranjan Mohanty, Edmond M. Linossi, Laura F. Dagley, Eleanor W. W. Leung, James M. Murphy, Jeffrey J. Babon, Sandra E. Nicholson, Raymond S. Norton · 2015 · Biochemistry
45. The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo
    Karen Doggett, Narelle Keating, Farhad Dehkhoda, Grace M. Bidgood, Lizeth G. Meza Guzman, Evelyn Leong, Andrew J. Kueh, Nicos Anthony Nicola, Nadia J. Kershaw, Jeffrey J. Babon et al. · 2023 · Cytokine
46. SOCS3 dictates the transition of divergent time-phased events in granulocyte TNF-α signaling
    Jasmeet Kaur Chhabra, Brajadulal Chattopadhyay, Bhola Nath Paul · 2013 · Cellular and Molecular Immunology
47. Unleashing Intrinsic Growth Pathways in Regenerating Peripheral Neurons
    Trevor M. Poitras, Douglas William Zochodne · 2022 · International Journal of Molecular Sciences
48. Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy
    Kaifeng Li, Boyi Li, Jiyun Li, Xiaoyi Wu, Yaning Zhao, Jian Ling Yu, Jingmei Guo, Cui Huang · 2024 · Trends in biotechnology
49. A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas
    Laura Gadeyne, Yannick Van Herck, Giorgia Milli, Zeynep Kalender Atak, Maddalena M. Bolognesi, Jasper Wouters, Lukas Marcelis, Angeliki Minia, Vaia Pliaka, Jan Roznac et al. · 2021 · Frontiers in Oncology
50. Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers
    Stefan N. Constantinescu, Emilie Leroy, Vitalina Gryshkova, Christian Pecquet, Alexandra Dusa · 2013 · Biochemical Society Transactions
51. TLT2 Suppresses Th1 Response by Promoting IL-6 Production in Monocyte Through JAK/STAT3 Signal Pathway in Tuberculosis
    Jinai Li, Can Cao, Yali Xiang, Zhongsi Hong, Duanman He, Haibo Zhong, Ye Liu, Yongjian Wu, Xiaobin Zheng, Huan Yin et al. · 2020 · Frontiers in Immunology
52. SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune tolerance
    Akihiko Yoshimura, Daisuke Aki, Minako Ito · 2021 · Proceedings of the Japan Academy Series B
53. Paeoniflorin suppresses IL-6/Stat3 pathway via upregulation of Socs3 in dendritic cells in response to 1-chloro-2,4-dinitrobenze
    Dongmei Shi, Qiong A Wang, Hailin Zheng, Dongmei Li, Yongnian Shen, Hongjun Fu, Tianhang Li, Huan Mei, Guixia Lü, Ying Qiu et al. · 2016 · International Immunopharmacology
54. Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression
    Kim, Eunsun, Cheng, Ying, Bolton-Gillespie, Elisabeth, Cai, Xiongwei, Ma, Connie, Tarangelo, Amy, Le, Linh, Jambhekar, Madhumita, Raman, Pichai, Hayer, Katharina E. et al. · 2017 · Journal of Experimental Medicine
55. Regulation of Macrophage Polarization by the STAT–SOCS Signaling Axis
    Sandra E. Nicholson, Peter J. Murray · 2014 · Springer eBooks
56. Medicinal chemistry perspective of JAK inhibitors: synthesis, biological profile, selectivity, and structure activity relationship
    Lalmohan Maji, Sindhuja Sengupta, Gurubasavaraja Swamy Purawarga Matada, Ghanshyam Teli, G. Biswas, Pronoy Kanti Das, Manjunatha Panduranga Mudgal · 2024 · Molecular Diversity
57. PEGylated SOCS3 Mimetics Encapsulated into PLGA-NPs as Selective Inhibitors of JAK/STAT Pathway in TNBC Cells
    Sara La Manna, Alessia Cugudda, Flavia Anna Mercurio, Marilisa Leone, Sara Fortuna, Concetta Di Natale, Elena Lagreca, Paolo A. Netti, Valeria Panzetta, Daniela Marasco · 2024 · International Journal of Nanomedicine
58. Delineating the regulation of energy homeostasis using hypothalamic cell models
    Leigh Wellhauser, Nicole M. Gojska, Denise D. Belsham · 2014 · Frontiers in Neuroendocrinology
59. CgSOCS6 negatively regulates the expression of CgIL17s and CgDefh1 in the pacific oyster Crassostrea gigas
    Zhaojun Wu, Jiejie Sun, Liyan Wang, Yanan Zong, Zirong Han, Wen Yang, Zhaoqun Liu, Lingling Wang, Linsheng Song · 2019 · Fish & Shellfish Immunology
60. Cullin-5 Adaptor SPSB1 Controls NF-κB Activation Downstream of Multiple Signaling Pathways
    Iliana Georgana, Carlos Maluquer de Motes · 2020 · Frontiers in Immunology
61. SOCS3 acts as a potential negative regulator in the antiviral response of large yellow croaker (Larimichthys crocea) by interacting with STAT1
    You Chen, Huazhi Chen, Shuaiwei Ren, Yangfan Xiao, Shuaichao Tao, Jiamei Liu, Xiaoqin Yuan, Xinhua Chen, Yinnan Mu · 2024 · Water Biology and Security
62. Structure of a Sedoheptulose 7-Phosphate Cyclase: ValA from Streptomyces hygroscopicus
    K.M. Kean, Sara J. Codding, Shumpei Asamizu, Taifo Mahmud, P. Andrew Karplus · 2014 · Biochemistry
63. IL-11 prevents IFN-γ-induced hepatocyte death through selective downregulation of IFN-γ/STAT1 signaling and ROS scavenging
    Akimitsu Miyawaki, Yoshiko Iizuka, Hitomi Sugino, Yoshifumi Watanabe · 2019 · PLoS ONE
64. SOCS3 is a suppressor of γc cytokine signaling and constrains generation of murine Foxp3 + regulatory T cells
    Megan A. Luckey, Tae‐Hyoun Kim, Praveen Prakhar, Hilary R. Keller, Assiatu Crossman, Seeyoung Choi, Paul E. Love, Scott T.R. Walsh, Jung‐Hyun Park · 2020 · European Journal of Immunology
65. The immunoregulatory role of fish specific type II SOCS via inhibiting metaflammation in the gut-liver axis
    Junwei Shan, Guangxin Wang, Heng Li, Xuyang Zhao, Weidong Ye, Lian Feng Su, Qingsong Zhu, Yuhang Liu, Yingyin Cheng, Wanting Zhang et al. · 2022 · Water Biology and Security
66. MicroRNAs as the critical regulators of epithelial mesenchymal transition in pancreatic tumor cells
    Faezeh Tolue Ghasaban, Mahmoud Ghanei, R. A. Mahmoudian, Negin Taghehchian, M. Abbaszadegan, M. Moghbeli · 2024 · Heliyon
67. Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction
    Chunshan Liu, Hsin‐Fang Yang‐Yen, Ching‐Shu Suen, Ming‐Jing Hwang, Jeffrey Jong-Young Yen · 2017 · Scientific Reports
68. CISH controls bacterial burden early after infection with Mycobacterium tuberculosis in mice
    Berit Carow, Yu Gao, Graciela Terán, Xuexian O. Yang, Chen Dong, Akihiko Yoshimura, Martı́n E. Rottenberg · 2017 · Tuberculosis
69. Innate and Autoimmunity in the Pathogenesis of Inherited Retinal Dystrophy
    TJ Hollingsworth, Alecia K. Gross · 2020 · Cells
70. The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells
    Ildar I. Sadreev, Michael Z. Q. Chen, Yoshinori Umezawa, Vadim Nadyrovich Biktashev, Claudia Kemper, Diana V. Salakhieva, Gavin Iain Welsh, Nikolay V. Kotov · 2017 · Immunology
71. Correlation of SOCS‑1 gene with onset and prognosis of breast cancer
    Yuetao Lv, Ge Song, Peng Li · 2018 · Oncology Letters
72. Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
    Samira Schiefer, Benjamin G. Hale · 2024 · Nature Communications
73. New insights into Chlamydia pathogenesis: Role of leukemia inhibitory factor
    Jun Wang, Katherine Wang · 2022 · Frontiers in Cellular and Infection Microbiology
74. Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas
    Koji Osuka, Yasuo Watanabe, Nobuteru Usuda, Masahiro Aoyama, Kenichiro Iwami, Mikinobu Takeuchi, Takeya Watabe, Masakazu Takayasu · 2016 · Journal of Neurotrauma
75. Atomistic insight into the inhibition mechanisms of suppressors of cytokine signaling on Janus kinase
    Yaru Wei, Zhiyang Zhang, Nai She, Xin Chen, Yuan Zhao, Jinglai Zhang · 2019 · Physical Chemistry Chemical Physics
76. Phosphorylation-Induced Conformational Dynamics and Inhibition of Janus Kinase 1 by Suppressors of Cytokine Signaling 1
    Md Fulbabu Sk, Nisha Amarnath Jonniya, Rajarshi Roy, Parimal Kar · 2022 · The Journal of Physical Chemistry B
77. Roles of leukemia inhibitory factor receptor in cancer
    Wei Ma, Haixu Yan, Haoyuan Ma, Zengyan Xu, Wei Dai, Yudan Wu, Hongyan Zhang, Y Li · 2024 · International Journal of Cancer
78. Identification of a second binding site on the TRIM25 B30.2 domain
    Akshay A. D’Cruz, Nadia J. Kershaw, Thomas J. Hayman, Edmond M. Linossi, Jessica J. Chiang, May K. Wang, Laura F. Dagley, Tatiana B. Kolesnik, Jian‐Guo Zhang, Seth Lucian Masters et al. · 2017 · Biochemical Journal
79. Pathogenic signaling in multiple myeloma
    Arnold Bolomsky, Ryan M. Young · 2022 · Seminars in Oncology
80. How GRAIL controls Treg function to maintain self-tolerance
    C. Garrison Fathman, Linda Yip, Diana Gómez‐Martín, Mang Yu, Christine M. Seroogy, Clarence R. Hurt, Jack T. Lin, Jennifer Anne Jenks, Kari Christine Nadeau, Luis R. B. Soares · 2022 · Frontiers in Immunology
81. Molecular signaling involving intrinsically disordered proteins in prostate cancer
    Daniela Marasco, Anna Russo, Sara La Manna, Ettore Novellino, Anna Maria Malfitano · 2016 · Asian Journal of Andrology
82. Leukaemia inhibitory factor in gastric cancer: friend or foe?
    Lornella Seeneevassen, Océane C. B. Martin, Philippe Lehours, Pierre R. Dubus, Christine Varon · 2022 · Gastric Cancer
83. Suppressor of cytokine signalling 3 is crucial for interleukin‐7 receptor re‐expression after T‐cell activation and interleukin‐7 dependent proliferation
    Alptekin Güler, Miguel Lopez Venegas, Ernest Adankwah, Ertan Mayatepek, Norman Nausch, Marc Jacobsen · 2019 · European Journal of Immunology
84. Translational Relevance of Secondary Intracellular Signaling Cascades Following Traumatic Spinal Cord Injury
    Mohammad-Masoud Zavvarian, Akshat D. Modi, Sarah Sadat, James Hong, Michael George Fehlings · 2024 · International Journal of Molecular Sciences
85. The role of leukemia inhibitory factor in pathogenesis of pre-eclampsia: molecular and cell signaling approach
    Mehrnaz Abdolalian, Maryam Ebrahimi, Mahansadat Aghamirzadeh, Nooshin Eshraghi, Mana Moghaddasi, Parvinsadat Eslamnik · 2021 · Journal of Molecular Histology
86. Targeting Microglial Disturbances to Protect the Brain From Neurodevelopmental Disorders Associated With Prematurity
    Andrée Delahaye‐Duriez, Adrien Dufour, Cindy Bokobza, Pierre Gressèns, Juliette Van Steenwinckel · 2021 · Journal of Neuropathology & Experimental Neurology
87. Lipocalin-2 promotes NSCLC progression by activating the JAK2/STAT3 signaling pathway
    Jinjin Zhang, Qin Lan Xu, Gengyun Sun · 2025 · Journal of Translational Medicine
88. Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival
    Christina Nicole Nikki Byrne-Hoffman, Wentao Deng, Owen McGrath, Peng Wang, Yon Rojanasakul, David J. Klinke · 2020 · Cell Communication and Signaling
89. Are peptidomimetics the compounds of choice for developing new modulators of the JAK-STAT pathway?
    Alessia Cugudda, Sara La Manna, Daniela Marasco · 2024 · Frontiers in Immunology
90. LncRNA BRE-AS1 regulates the JAK2/STAT3-mediated inflammatory activation via the miR-30b-5p/SOC3 axis in THP-1 cells
    Jae-Joon Shin, Kyoungho Suk, Won‐Ha Lee · 2024 · Scientific Reports
91. The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury
    Zhenlu Cai, Zixuan Zhang, Liyun Zhang, Ruolan Tan, Yu Wang, Meiqi Sun, Xiaoxuan Hu, Qian Ge, Jing An, Haixia Lü · 2023 · Journal of Chemical Neuroanatomy
92. CRISPR screens and quantitative proteomics reveal remodeling of the aryl hydrocarbon receptor–driven proteome through PARP7 activity
    Andrii Gorelik, João A. Paulo, Christina B. Schroeter, Melanie Lad, Abigail Shurr, Chara Mastrokalou, Samrah Siddiqi, Osamu Suyari, John Brognard, David Walter et al. · 2025 · Proceedings of the National Academy of Sciences
93. Structure-Activity Relationship Investigations of Novel Constrained Chimeric Peptidomimetics of SOCS3 Protein Targeting JAK2
    Sara La Manna, Marilisa Leone, Flavia Anna Mercurio, Daniele Florio, Daniela Marasco · 2022 · Pharmaceuticals
94. Diverse signaling mechanisms and heterogeneity of astrocyte reactivity in Alzheimer's disease
    Hongwei Qin, Lianna Zhou, Faris T. Haque, Cynthia Martín-Jiménez, Amy Trang, Etty N. Benveniste, Qin Wang · 2023 · Journal of Neurochemistry
95. Promotion of Erythropoietic Differentiation in Hematopoietic Stem Cells by SOCS3 Knock-Down
    Yuxiao Liu, Xing Dong, Feng Gong, Ning Su, Su-Bo Li, Haitao Zhang, Jia-Ling Liu, Jing-hui Xue, Shouping Ji, Zhiwen Zhang · 2015 · PLoS ONE
96. Optimization of Phosphotyrosine Peptides that Target the SH2 Domain of SOCS1 and Block Substrate Ubiquitination
    Hao Chen, Yuntong Wu, Kunlun Li, Iain Currie, Narelle Keating, Farhad Dehkhoda, Christoph Grohmann, Jeffrey J. Babon, Sandra E. Nicholson, Brad E. Sleebs · 2022 · ACS Chemical Biology
97. Therapeutic Effects of Tofacitinib on Pristane-Induced Murine Lupus
    Jiayi Lin, Yaqin ZHANG, Meihua Wang, Zhang Yang, Li Pin, Yingping Cao, Xuwei Yang · 2022 · Archives of Rheumatology
98. The Neglected Suppressor of Cytokine Signalling (SOCS): SOCS4-7
    Júber Herrera-Uribe, Orla Convery, Daniah Hameed Almohammadi, Fabienne Ingrid Weinberg, Nigel J. Stevenson · 2024 · Inflammation
99. The role of suppressor of cytokine signaling 3 in inflammatory bowel disease and its associated colorectal cancer
    Pengfei Zhang, Bing Pei, Chengxue Yi, Francis Atim Akanyibah, Fei Mao · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
100. SH2 Domain Structures and Interactions
     Piraveen Gopalasingam, Lee Quill, Mark Jeeves, Michael Overduin · 2015 · Springer eBooks