Crystal structure of a Rad51 filament

Conway, Adam B, Lynch, Thomas W, Zhang, Ying, Fortin, Gary S, Fung, Cindy W, Symington, Lorraine S, Rice, Phoebe A·2004·Nature Structural & Molecular Biology

Cited by (310)

Items 101–200 of 310

  1. In vivo tracking of functionally tagged Rad51 unveils a robust strategy of homology search
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  2. Structural Analysis of Shu Proteins Reveals a DNA Binding Role Essential for Resisting Damage
    Yuyong Tao, Xu Li, Yiwei Liu, Jianbin Ruan, Shali Qi, Liwen Niu, Maikun Teng · 2012 · Journal of Biological Chemistry
  3. GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
    Yoshimasa Takizawa, Yong Qing, Motoki Takaku, Takako Ishida, Yuichi Morozumi, Takashi Tsujita, Toshiaki Kogame, Kouji Hirota, Masayuki Takahashi, Takehiko Shibata et al. · 2010 · Nucleic Acids Research
  4. Protein splicing of a recombinase intein induced by ssDNA and DNA damage
    Christopher W. Lennon, Matthew J. Stanger, Marlene Belfort · 2016 · Genes & Development
  5. Single-Stranded DNA Curtains for Studying Homologous Recombination
    C.J. Ma, Justin B. Steinfeld, Eric C. Greene · 2016 · Methods in enzymology on CD-ROM/Methods in enzymology
  6. Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery
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  7. Biochemistry of Eukaryotic Homologous Recombination
    Wolf‐Dietrich Heyer · 2006 · Springer eBooks
  8. Interrogation of the Protein-Protein Interactions between Human BRCA2 BRC Repeats and RAD51 Reveals Atomistic Determinants of Affinity
    Daniel J. Cole, Eeson Rajendra, Meredith Roberts-Thomson, Bryn S. Hardwick, Grahame J. McKenzie, Mike C. Payne, Ashok R. Venkitaraman, Chris‐Kriton Skylaris · 2011 · PLoS Computational Biology
  9. Exploring the roles of PALB2 at the crossroads of DNA repair and cancer
    Joris Pauty, Amélie Rodrigue, Anthony M. Couturier, Rémi Buisson, Jean‐Yves Masson · 2014 · Biochemical Journal
  10. Regulation of Hed1 and Rad54 binding during maturation of the meiosis‐specific presynaptic complex
    J. Brooks Crickard, Kyle Kaniecki, Youngho Kwon, Patrick Sung, Michael Lisby, Eric C. Greene · 2018 · The EMBO Journal
  11. RAD18 lives a double life: Its implication in DNA double-strand break repair
    Ting Liu, Huang Jun, Chen Junjie · 2010 · DNA repair
  12. Nanoscopic exclusion between Rad51 and 53BP1 after ion irradiation in human HeLa cells
    Judith Reindl, Guido A Drexler, Stefanie Girst, Christoph Greubel, Christian Siebenwirth, Sophie E Drexler, Günther Dollinger, Anna A. Friedl · 2015 · Physical Biology
  13. Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites
    Kalina T. Haas, Mi-Young Lee, Alessandro Esposito, Ashok R. Venkitaraman · 2017 · Nucleic Acids Research
  14. Representation of viruses in the remediated PDB archive
    Catherine L. Lawson, Shuchismita Dutta, John Westbrook, Kim Henrick, Helen Miriam Berman · 2008 · Acta Crystallographica Section D Biological Crystallography
  15. Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates
    Kirk Tevebaugh Ehmsen, Wolf‐Dietrich Heyer · 2008 · Genome dynamics and stability
  16. The Human Rad51 K133A Mutant Is Functional for DNA Double-Strand Break Repair in Human Cells
    Anthony L. Forget, Matthew S. Loftus, Dharia A. McGrew, Brian T. Bennett, Kendall L. Knight · 2007 · Biochemistry
  17. ATP hydrolysis Promotes Duplex DNA Release by the RecA Presynaptic Complex
    Ja Yil Lee, Zhi Qi, Eric C. Greene · 2016 · Journal of Biological Chemistry
  18. RADX controls RAD51 filament dynamics to regulate replication fork stability
    Madison B. Adolph, Taha Mahdy Mohamed, Swati Balakrishnan, Chaoyou Xue, Florian Morati, Mauro Modesti, Eric C. Greene, Walter Chazin, David Cortez · 2021 · Molecular Cell
  19. Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures
    Shih‐Chi Luo, Hsin‐Yi Yeh, Wei-Hsuan Lan, Yimin Wu, Cheng‐Han Yang, Hao-Yen Chang, Guan-Chin Su, Chia‐Yi Lee, Wen‐Jin Wu, Hung‐Wen Li et al. · 2021 · Nature Communications
  20. Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant
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  21. Crystal Structure of the Phage T4 Recombinase UvsX and Its Functional Interaction with the T4 SF2 Helicase UvsW
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  22. Conformational flexibility revealed by the crystal structure of a crenarchaeal RadA
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  23. Mechanism and significance of chromosome damage repair by homologous recombination
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  24. Structural and functional analyses of the DMC1-M200V polymorphism found in the human population
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  25. Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica
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  26. EgoNet: identification of human disease ego-network modules
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  27. Homologous recombination–deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants
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  28. The Bacterial RecA Protein: Structure, Function, and Regulation
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  29. Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51
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  30. Complementation of One RecA Protein Point Mutation by Another
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  31. Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes
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  32. Probing Rad51-DNA interactions by changing DNA twist
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  35. Cooperative Conformational Transitions Keep RecA Filament Active During ATPase Cycle
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  36. Long repeating (TTAGGG) single-stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation
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  37. Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase
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  38. Mechanisms of Maintaining Genetic Stability by Homologous Recombination
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    Martin Lee, Jan Lipfert, Humberto Sánchez, Claire Wyman, Nynke H. Dekker · 2013 · Nucleic Acids Research
  40. Role of the N-terminal Domain of the Human DMC1 Protein in Octamer Formation and DNA Binding
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  41. Visualizing the Disassembly of S. cerevisiae Rad51 Nucleoprotein Filaments
    Ragan B. Robertson, Dana N. Moses, Youngho Kwon, Pamela Chan, Weixing Zhao, Peter Chi, Hannah L. Klein, Patrick Sung, Eric C. Greene · 2009 · Journal of Molecular Biology
  42. Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination
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  43. Role of DNA repair in the protection against genotoxic stress
    Ulrike Camenisch, Hanspeter Naegeli · 2009 · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions
  44. RAD51 and XRCC3 polymorphisms: Impact on the risk and treatment outcomes of de novo inv(16) or t(16;16)/CBFβ–MYH11(+) acute myeloid leukemia
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  45. Putting together and taking apart: assembly and disassembly of the Rad51 nucleoprotein filament in DNA repair and genome stability
    Tadas Andriuskevicius, Oleksii Kotenko, Svetlana Makovets · 2018 · Cell Stress
  46. A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly
    Robert E Appleby, Daniel Bollschweiler, Dimitri Y. Chirgadze, Luay I. Joudeh, Luca Pellegrini · 2023 · iScience
  47. Targeting the homologous recombination pathway by small molecule modulators
    Fei Huang, Alexander V. Mazin · 2014 · Bioorganic & Medicinal Chemistry Letters
  48. Sensing Conformational Changes in DNA upon Ligand Binding Using QCM-D. Polyamine Condensation and Rad51 Extension of DNA Layers
    Lu Sun, Karolin Frykholm, Louise Fornander, Sofia Svedhem, Fredrik Westerlund, Björn Åkerman · 2014 · The Journal of Physical Chemistry B
  49. Rec2 Interplay with both Brh2 and Rad51 Balances Recombinational Repair in Ustilago maydis
    Milorad Kojić, Qingwen Zhou, Michael Lisby, William K. Holloman · 2005 · Molecular and Cellular Biology
  50. An Integrative Approach to the Study of Filamentous Oligomeric Assemblies, with Application to RecA
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  51. Structural and Functional Analyses of Five Conserved Positively Charged Residues in the L1 and N-Terminal DNA Binding Motifs of Archaeal RadA Protein
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  52. Stimulation of Dmc1-mediated DNA strand exchange by the human Rad54B protein
    Naoyuki Sarai, Wataru Kagawa, Takashi Kinebuchi, Ako Kagawa, Kozo Tanaka, Kiyoshi Miyagawa, S Ikawa, Takehiko Shibata, Hitoshi Kurumizaka, Shigeyuki Yokoyama · 2006 · Nucleic Acids Research
  53. Structure of the hDmc1-ssDNA Filament Reveals the Principles of Its Architecture
    Andrei L. Okorokov, Yuriy L. Chaban, Dmitry V. Bugreev, Julie L. Hodgkinson, Alexander V. Mazin, Elena V. Orlova · 2010 · PLoS ONE
  54. Single-molecule views on homologous recombination
    Andrea Candelli, Mauro Modesti, Erwin J.G. Peterman, Gijs J. L. Wuite · 2013 · Quarterly Reviews of Biophysics
  55. Homologous recombination properties of OsRad51, a recombinase from rice
    Rajani Kant Chittela, Michael Melzer, Basuthkar J. Rao, Jayashree Krishna Sainis · 2008 · Plant Molecular Biology
  56. Advances in structural studies of recombination mediator proteins
    Sergey Korolev · 2016 · Biophysical Chemistry
  57. OB-fold Families of Genome Guardians: A Universal Theme Constructed From the Small β-barrel Building Block
    Piero R. Bianco · 2022 · Frontiers in Molecular Biosciences
  58. Gly-103 in the N-terminal Domain of Saccharomyces cerevisiae Rad51 Protein Is Critical for DNA Binding
    Xiao-Ping Zhang, Kyung Im Lee, Jachen A. Solinger, Kostantin Kiianitsa, Wolf‐Dietrich Heyer · 2005 · Journal of Biological Chemistry
  59. Right or left turn? RecA family protein filaments promote homologous recombination through clockwise axial rotation
    Ting‐Fang Wang, Li‐Tzu Chen, Andrew H.‐J. Wang · 2007 · BioEssays
  60. Structural mechanism of strand exchange by the RAD51 filament
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  61. Helical Filaments of Human Dmc1 Protein on Single-Stranded DNA: A Cautionary Tale
    Xiong Yu, Edward H. Egelman · 2010 · Journal of Molecular Biology
  62. Transcriptome Analysis of Thermal Parthenogenesis of the Domesticated Silkworm
    Peigang Liu, Yongqiang Wang, Xin Du, Lusong Yao, Fengbo Li, Zhiqi Meng · 2015 · PLoS ONE
  63. RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects
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  64. Dynamic interactions of the homologous pairing 2 (Hop2)–meiotic nuclear divisions 1 (Mnd1) protein complex with meiotic presynaptic filaments in budding yeast
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  65. Archaeal Genome Guardians Give Insights into Eukaryotic DNA Replication and Damage Response Proteins
    David S. Shin, Ashley J. Pratt, John A. Tainer · 2014 · Archaea
  66. Engineering Archeal Surrogate Systems for the Development of Protein–Protein Interaction Inhibitors against Human RAD51
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  67. Defective Dissociation of a “Slow” RecA Mutant Protein Imparts an Escherichia coli Growth Defect
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  69. Crystal Structure of an Archaeal Rad51 Homologue in Complex with a Metatungstate Inhibitor
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  70. A novel motif of Rad51 serves as an interaction hub for recombination auxiliary factors
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