Molecular mechanisms of cisplatin resistance

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1. Pharmacological inhibition of NADPH oxidase protects against cisplatin induced nephrotoxicity in mice by two step mechanism
   Yimin Wang, Xiao Luo, Hao Pan, Wei Huang, Xueping Wang, Huali Wen, Kezhen Shen, Baiye Jin · 2015 · Food and Chemical Toxicology
2. Photothermal Conjugated Polymer Nanoparticles for Suppressing Breast Tumor Growth by Regulating TRPA1 Ion Channels
   Boying Li, Shuxi Ren, Dong Mei Gao, Ning Li, Manman Wu, Hongbo Yuan, Mei Zhou, Chengfen Xing · 2021 · Advanced Healthcare Materials
3. Curcumin Synergizes with Cisplatin to Inhibit Colon Cancer through Targeting the MicroRNA-137-Glutaminase Axis
   Wen-hui Fan, Fengchun Wang, Zhi Jin, Lin Zhu, Jianxin Zhang · 2021 · Current Medical Science
4. Current Treatments and New Possible Complementary Therapies for Epithelial Ovarian Cancer
   Maritza P. Garrido, Allison N. Fredes, Lorena Lobos‐González, Manuel Valenzuela, Daniela B. Vera, Carmen Romero · 2021 · Biomedicines
5. Combination of Systemic Chemotherapy with Local Stem Cell Delivered S-TRAIL in Resected Brain Tumors
   Navid Redjal, Yanni Zhu, Khalid Shah · 2014 · Stem Cells
6. Global tumor protein p53/p63 interactome
   Yiping Huang, Jun Seop Jeong, Jun Okamura, Myoung Sook-Kim, Heng Zhu, Rafael E. Guerrero-Preston, Edward A. Ratovitski · 2012 · Cell Cycle
7. PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice
   Darío García‐Carracedo, Yi Cai, Wanglong Qiu, Kiyoshi Saeki, Richard A. Friedman, Andrew H. Lee, Yinglu Li, Elizabeth M. Goldberg, Ηλίας Στρατικόπουλος, Ramon E. Parsons et al. · 2020 · Molecular Cancer Research
8. ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer
   Jie Li, Cuimiao Zheng, Mingshuo Wang, Anna D. Umano, Qingyuan Dai, Chunyu Zhang, Hua Huang, Qing Yang, Xianzhi Yang, Jingyi Lu et al. · 2022 · Oncogene
9. Cisplatin-activated ERβ/DCAF8 positive feedback loop induces chemoresistance in non-small cell lung cancer via PTEN/Akt axis
   Yumeng Hu, Yongjie Xu, Ting Zhang, Qianying Han, Li Li, Mingyang Liu, Ni Li, Genze Shao · 2023 · Drug Resistance Updates
10. Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity
    Jian Gu, Li Yu, Qiuyang Chen, Ziyan Song, Qufei Qian, Yuan Liang, Tianning Huang, Lei Qiao, Xiangyu Li, Mei Yu et al. · 2025 · Cell
11. Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury
    Katharina Krüger, Jürgen Thomale, Nikolina Stojanović, Maja Osmak, Christian Henninger, Stefanie Bormann, Gerhard Fritz · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
12. ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics
    Zhongqi Fan, Huimei Yu, Ni Cui, Xianggui Kong, Xiaomin Liu, Yulei Chang, Yao Wu, Liankun Sun, Guangyi Wang · 2015 · Experimental Cell Research
13. Cisplatin modulates B-cell translocation gene 2 to attenuate cell proliferation of prostate carcinoma cells in both p53-dependent and p53-independent pathways
    Kun‐Chun Chiang, Ke-Hung Tsui, Li‐Chuan Chung, Chun‐Nan Yeh, Tsui‐Hsia Feng, Wen‐Tsung Chen, Phei‐Lang Chang, Hou‐Yu Chiang, Horng‐Heng Juang · 2014 · Scientific Reports
14. Matrine induces mitochondrial apoptosis in cisplatin-resistant non-small cell lung cancer cells via suppression of β-catenin/survivin signaling
    HUAN-QIN WANG, Jianjun Jin, Jing Wang · 2015 · Oncology Reports
15. Quantum Dots as Multifunctional Materials for Tumor Imaging and Therapy
    Longfei Liu, Qingqing Miao, Gaolin Liang · 2013 · Materials
16. Intracellular GSH Alterations and Its Relationship to Level of Resistance following Exposure to Cisplatin in Cancer Cells.
    Bardia Jamali, Maryam Nakhjavani, Leila Hosseinzadeh, Salimeh Amidi, Nastaran Nikounezhad, Farshad H. Shirazi · 2015 · PubMed Central
17. Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models
    Amanda F. Baker, Neale T. Hanke, Barbara J. Sands, Liliana Carbajal, Janet L. Anderl, Linda L. Garland · 2014 · Journal of Experimental & Clinical Cancer Research
18. Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin
    Davide Cervia, Emma Assi, Clara De Palma, Matteo Giovarelli, Laura Bizzozero, Sarah Pambianco, Ilaria Di Renzo, Silvia Zecchini, Claudia Moscheni, Chiara Vantaggiato et al. · 2016 · Oncotarget
19. Pharmacogenetics of platinum-based chemotherapy in non-small cell lung cancer: predictive validity of polymorphisms of ERCC1
    Gerhard Hamilton, Barbara Rath · 2017 · Expert Opinion on Drug Metabolism & Toxicology
20. Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells
    Kristina Shilnikova, Mei Jing Piao, Kyoung Ah Kang, Yea Seong Ryu, Jeong Park, Yu Hyun, Ao Xuan Zhen, Yong Jeong, Uhee Jung, In Kim et al. · 2018 · Oncology Letters
21. In vitro FTIR microspectroscopy analysis of primary oral squamous carcinoma cells treated with cisplatin and 5-fluorouracil: a new spectroscopic approach for studying the drug–cell interaction
    Elisabetta Giorgini, Simona Sabbatini, Romina Rocchetti, Valentina Notarstefano, Corrado Rubini, Carla Conti, Giulia Orilisi, Elisa Mitri, Diana Eva Bedolla, Lisa Vaccari · 2018 · The Analyst
22. 5-O-Acetyl-Renieramycin T from Blue Sponge Xestospongia sp. Induces Lung Cancer Stem Cell Apoptosis
    Wipa Chantarawong, Supakarn Chamni, Khanit Suwanborirux, Naoki Saito, Pithi Chanvorachote B · 2019 · Marine Drugs
23. Targeting NF-κB-mediated inflammatory pathways in cisplatin-resistant NSCLC
    Sarah-Louise Ryan, Sam Beard, Martin P. Barr, Kazou Umezawa, Susan Heavey, Peter Godwin, Steven G. Gray, David Cormican, Stephen P. Finn, Kathy A. Gately et al. · 2019 · Lung Cancer
24. The role of pyruvate kinase M2 in anticancer therapeutic treatments (Review)
    Qiongli Su, Shengping Luo, Qiuhong Tan, Jun Deng, Sichun Zhou, Mei Peng, Ting Tao, Xiaoping Yang · 2019 · Oncology Letters
25. (−)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells
    Jing Wang, Pei-Yuan Sun, Qi Wang, Pan Zhang, Yuna Wang, Cheng-Ting Zi, Xuan-Jun Wang, J. Sheng · 2019 · Cancer Cell International
26. A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer
    Atish Ranjan Mohanty, Arin Nam, Alexander E. Pozhitkov, S. Bhattacharya, Lu Yang, Anusha Nathan, Xiwei Wu, Saumya Srivastava, Isa Mambetsariev, Michael Nelson et al. · 2020 · iScience
27. Regulated cell death in cisplatin-induced AKI: relevance of myo-inositol metabolism
    Fei Deng, Xiaoping Zheng, Isha Sharma, Yingbo Dai, Yinhuai Wang, Yashpal S. Kanwar · 2021 · American Journal of Physiology-Renal Physiology
28. Ginsenoside Rg3 Alleviates Cisplatin Resistance of Gastric Cancer Cells Through Inhibiting SOX2 and the PI3K/Akt/mTOR Signaling Axis by Up-Regulating miR-429
    Xiaofeng Wang, Rui He, Li Geng, Jing Yuan, Huijie Fan · 2022 · Frontiers in Genetics
29. Synthesis of selenazolopyridine derivatives with capability to induce apoptosis in human breast carcinoma MCF-7 cells through scavenge of intracellular ROS
    Mei‐Yun Zhou, Shengbin Ji, Zhaojun Wu, Yiqun Li, Wenjie Zheng, Hua Zhou, Tianfeng Chen · 2015 · European Journal of Medicinal Chemistry
30. Targeting Apoptosis to Overcome Chemotherapy Resistance
    Eda Doğan, Hale Güler Kara, Buket Kosova, Vildan Bozok Çetintaş · 2021 · Exon Publications eBooks
31. EZH2 Inhibition and Cisplatin as a Combination Anticancer Therapy: An Overview of Preclinical Studies
    Ivana Samaržija, Marko Tomljanović, Renata Novak Kujundžić, Koraljka Gall‐Tros̆elj · 2022 · Cancers
32. The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancer
    Liangliang Ren, Xingrong Qing, Jihong Wei, Haixin Mo, Yuanji Liu, Yaofeng Zhi, Wenjie Lu, Mingzhu Zheng, Weijian Zhang, Yuan Chen et al. · 2023 · Cell Death and Disease
33. Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin
    Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, Guo‐Jun Zhang · 2014 · Oncotarget
34. Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug
    Rong Ma, Zhigang Wang, Li Yan, Xianfeng Chen, Guangyu Zhu · 2014 · Journal of Materials Chemistry B
35. Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro
    Bruno Corrêa Bellagamba, Bianca Regina Ribas de Abreu, Ivana Grivicich, Carolina Franke, Eduardo Mainieri Chem, Melissa Camassola, Nance Beyer Nardi, Rafael Rodrigues Dihl · 2016 · Genetics and Molecular Biology
36. Tumor-targeted supramolecular nanoparticles self-assembled from a ruthenium-β-cyclodextrin complex and an adamantane-functionalized peptide
    Shan-Shan Xue, Cai‐Ping Tan, Mu‐He Chen, Jianjun Cao, Dongyang Zhang, Rui‐Rong Ye, Liang‐Nian Ji, Zong‐Wan Mao · 2016 · Chemical Communications
37. Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer
    Daniel Kritsch, Franziska S. Hoffmann, Daniel Steinbach, Lars Jansen, Stella Mary Photini, Mieczyslaw R. Gajda, Alexander Sandy Mosig, Jürgen Sonnemann, Sven Peters, Margarita Melnikova et al. · 2017 · International Journal of Cancer
38. New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools
    Sandra Muñoz-Galván, Blanca Felipe‐Abrio, Miguel García-Carrasco, Julia Domínguez-Piñol, Elisa Suárez-Martínez, Eva M. Verdugo‐Sivianes, Asunción Espinosa-Sánchez, Lola E. Navas, Daniel Otero-Albiol, Juan Marín et al. · 2019 · Journal of Experimental & Clinical Cancer Research
39. Restoration and Enhancement of Immunogenic Cell Death of Cisplatin by Coadministration with Digoxin and Conjugation to HPMA Copolymer
    Yucheng Xiang, Liqiang Chen, Lian Li, Yuan Huang · 2019 · ACS Applied Materials & Interfaces
40. Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting the RAS/RAF Pathway, Enhancing Antitumor Activity, and Overcoming Multidrug Resistance
    Zhikun Liu, Meng Wang, Heng‐Shan Wang, Lei Fang, Shaohua Gou · 2019 · Journal of Medicinal Chemistry
41. DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression
    Jia-En Wu, Yi-Ying Wu, Chia-Hao Tung, Yao-Tsung Tsai, Hsuan‐Yu Chen, Yuh‐Ling Chen, Tse-Ming Hong · 2020 · Theranostics
42. Overcoming Limitations of Cisplatin Therapy by Additional Treatment With the HSP90 Inhibitor Onalespib
    Anja Charlotte Lundgren Mortensen, Tabassom Mohajershojai, Mehran Hariri, Marika Pettersson, Diana Spiegelberg · 2020 · Frontiers in Oncology
43. Anticancer Gold(III) Compounds With Porphyrin or N-heterocyclic Carbene Ligands
    Ka‐Chung Tong, Di Hu, Pui‐Ki Wan, Chun‐Nam Lok, Chi‐Ming Che · 2020 · Frontiers in Chemistry
44. Mechanisms of Pharmaceutical Therapy and Drug Resistance in Esophageal Cancer
    Chengyi Mao, Xiaoxi Zeng, Chao Zhang, Yu‐Shang Yang, Xin Xiao, Siyuan Luan, Yonggang Zhang, Yong Yuan · 2021 · Frontiers in Cell and Developmental Biology
45. The Synergistic Combination of Cisplatin and Piperine Induces Apoptosis in MCF-7 Cell Line
    Abolfazl Fattah, Ali Morovati, Zahra Niknam, Ladan Mashouri, Amirhooman Asadi, Shirin Tvangar Rizi, Mojtaba Abbasi, Fatemeh Shakeri, Omid Abazari · 2021 · Iranian Journal of Public Health
46. LncRNA CARMN overexpression promotes prognosis and chemosensitivity of triple negative breast cancer via acting as miR143-3p host gene and inhibiting DNA replication
    Xiaonan Sheng, Huijuan Dai, Yueyao Du, Jing Peng, Rui Sha, Fan Yang, Liheng Zhou, Yanping Lin, Shuguang Xu, Yifan Wu et al. · 2021 · Journal of Experimental & Clinical Cancer Research
47. Extremely low frequency electromagnetic field sensitizes cisplatin-resistant human ovarian adenocarcinoma cells via P53 activation
    Javad Baharara, Nasrin Hosseini, Tayebe Ramezani · 2015 · Cytotechnology
48. Reduced SLC27A2 induces cisplatin resistance in lung cancer stem cells by negatively regulating Bmi1‐ABCG2 signaling
    Jie Susie Su, Shifei Wu, Wei Dong Tang, Hui Qian, Hui Zhou, Tao Guo · 2015 · Molecular Carcinogenesis
49. A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy
    Joanna Somers, Lindsay A. Wilson, John‐Paul Kilday, Emilie Horvilleur, Ian Gordon Cannell, Tuija A. A. Pöyry, Laura C. Cobbold, Alexander Kondrashov, John R. P. Knight, Stéphanie Puget et al. · 2015 · Genes & Development
50. The role of Extracellular Vesicles in glycolytic and lipid metabolic reprogramming of cancer cells: Consequences for drug resistance
    Bárbara Raquel Gomes Polónia, Cristina P. R. Xavier, Joanna Kopecka, Chiara Riganti, M. Helena Vasconcelos · 2023 · Cytokine & Growth Factor Reviews
51. Multifunctional Iridium(III)–Platinum(IV) Conjugates as Potent Anticancer Theranostic Agents
    Ajay Gupta, Abhishek Kumar Pandey, Titas Mondal, Jaydeep Bhattacharya, Pijus K. Sasmal · 2023 · Journal of Medicinal Chemistry
52. TP53 K351N mutation-associated platinum resistance after neoadjuvant chemotherapy in patients with advanced ovarian cancer
    Guonan Zhang, Hong Liu, Jianming Huang, Ling Wang, Jing-sha Zhao, Chao Li, Kun Mi, Yi Zhu, Jia Zhen Cheng, Xiao Zha · 2014 · Gynecologic Oncology
53. Cisplatin binds to human copper chaperone Cox17: the mechanistic implication of drug delivery to mitochondria
    Linhong Zhao, Qinqin Cheng, Zhen Wang, Zhaoyong Xi, Dechen Xu, Yangzhong Liu · 2014 · Chemical Communications
54. HMGB1 bound to cisplatin–DNA adducts undergoes extensive acetylation and phosphorylation in vivo
    Yafeng He, Yin Ding, Dan Wang, Wanjun Zhang, Weizhong Chen, Xichun Liu, Weijie Qin, Xiaohong Qian, Hao Chen, Zijian Guo · 2014 · Chemical Science
55. Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma
    Zhongwu Su, Guo Li, Chao Liu, Shuling Ren, Tengbo Deng, Shuiting Zhang, Yongquan Tian, Yong Liu, Yuanzheng Qiu · 2017 · Oncology Letters
56. Mathematical Modeling Predicts Response to Chemotherapy and Drug Combinations in Ovarian Cancer
    Emilia Kozłowska, Anniina Färkkilä, Tuulia Vallius, Olli Carpén, Jukka Kemppainen, Seija Grénman, Rainer Lehtonen, Johanna Hynninen, Sakari Hietanen, Sampsa Hautaniemi · 2018 · Cancer Research
57. Recovery of miR-139-5p in Ovarian Cancer Reverses Cisplatin Resistance by Targeting C-Jun
    Ying Jiang, Jing Jiang, Haiqing Jia, Zhiwei Qiao, Jingru Zhang · 2018 · Cellular Physiology and Biochemistry
58. IL-1β Inflammatory Cytokine-Induced TP63 Isoform ∆NP63α Signaling Cascade Contributes to Cisplatin Resistance in Human Breast Cancer Cells
    Mónica Mendoza-Rodríguez, Jorge Tonatiuh Ayala-Sumuano, Lázaro García-Morales, Horacio Zamudio‐Meza, Eloy Andrés Pérez-Yépez, Isaura Meza · 2019 · International Journal of Molecular Sciences
59. JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells
    Lei Duan, Ricardo E. Perez, Paul D. Chastain, Mathew T. Mathew, Divya Rani Bijukumar, Carl G. Maki · 2019 · Oncogene
60. Synthesis, characterization and biological activities of imidazo[1,2-a]pyridine based gold(III) metal complexes
    Darshana N. Kanthecha, Bhupesh S. Bhatt, Mohan N. Patel · 2019 · Heliyon
61. Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis
    Lihan Xie, Asavari Rajpurkar, Ellen K. Quarles, Nicole Taube, Sivah Akash, Jake Erba, Benjamin Sliwinski, Moses I. Markowitz, Ursula Jakob, Daniela Knoefler · 2019 · Frontiers in Oncology
62. Developing a Novel Indium(III) Agent Based on Liposomes to Overcome Cisplatin-Induced Resistance in Breast Cancer by Multitargeting the Tumor Microenvironment Components
    Ming Jiang, Yong Chu, Tongfu Yang, Wenjuan Li, Zhenlei Zhang, Hongbin Sun, Hong Liang, Feng Yang · 2021 · Journal of Medicinal Chemistry
63. Improved Immunotherapy for Gastric Cancer by Nanocomposites with Capability of Triggering Dual-Damage of Nuclear/Mitochondrial DNA and Cgas/Sting-Mediated Innate Immunity
    Weihong Guo, Zhian Chen, Zhenhao Li, Huilin Huang, Yingxin Ren, Bingxia Zhao, Guoxin Li, Yanfeng Hu · 2022 · Chemical Engineering Journal
64. Biomedical,clinical and environmental applications of platinum-based nanohybrids: An updated review
    Sachin T. Yerpude, Ajay K. Potbhare, Pavan R. Bhilkar, Alok R. Rai, Raghvendra Pratap Singh, Ahmed A. Abdala, Rameshwar Adhikari, Rohit Sharma, Ratiram Gomaji Chaudhary · 2023 · Environmental Research
65. Inhibition of cisplatin-resistance by RNA interference targeting metallothionein using reducible oligo-peptoplex
    Jong‐Hwan Lee, Ji-Won Chae, Jang Kyoung Kim, Hyung Jin Kim, Jee Young Chung, Yong‐Hee Kim · 2015 · Journal of Controlled Release
66. Mitochondrial fusion: A mechanism of cisplatin-induced resistance in neuroblastoma cells?
    Giada Santin, Valeria Maria Piccolini, Sergio Barni, Paola Veneroni, Vincenzo Giansanti, Veronica Dal Bo, Graziella Bernocchi, Maria Grazia Bottone · 2012 · NeuroToxicology
67. Bladder Cancer Chemosensitivity Is Affected by Paraoxonase-2 Expression
    Stefania Fumarola, Monia Cecati, Davide Sartini, Gianna Ferretti, Giulio Milanese, Andrea Benedetto Galosi, Valentina Pozzi, Roberto Campagna, Camilla Morresi, Monica Emanuelli et al. · 2020 · Antioxidants
68. Activation of ABCC Genes by Cisplatin Depends on the CoREST Occurrence at Their Promoters in A549 and MDA-MB-231 Cell Lines
    Maciej Sobczak, Magdalena Strachowska, Karolina Gronkowska, Agnieszka Robaszkiewicz · 2022 · Cancers
69. Recent updates in nanoscale delivery systems of platinum(IV) antitumor prodrugs
    Zhiyuan Zhou, Pengmin Shi, Changli Wang, Yan-Yan Sun, Chuan-Zhu Gao · 2024 · Coordination chemistry reviews
70. Low molecular weight heparin tinzaparin antagonizes cisplatin resistance of ovarian cancer cells
    Daniel Bastian Pfankuchen, Daniel Philipp Stölting, Martin Schlesinger, Hans‐Dieter Royer, Gerd Bendas · 2015 · Biochemical Pharmacology
71. Identification of Transmembrane Protein 98 as a Novel Chemoresistance-Conferring Gene in Hepatocellular Carcinoma
    TP Ng, Chung Mau Lo, Dong Yong Guo, Xiang Qi, Chang Xian Li, Wei Geng, Xiao Bing Liu, Chang Chun Ling, Yuen Yuen, Wai Ho Yeung et al. · 2014 · Molecular Cancer Therapeutics
72. Curcumin as a cancer chemotherapy sensitizing agent
    Youngjoo Kwon · 2014 · Journal of the Korean Society for Applied Biological Chemistry
73. Inhibition of disheveled-2 resensitizes cisplatin-resistant lung cancer cells through down-regulating Wnt/β-catenin signaling
    Ke Luo, Xiuhui Gu, Jing Liu, Guodan Zeng, Liaotian Peng, Houyi Huang, Mengju Jiang, Ping Yang, Minhui Li, Yuhan Yang et al. · 2016 · Experimental Cell Research
74. In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl(CO)(dppb)(bipy)]PF6[dppb = 1,4-bis(diphenylphosphine)butane and bipy = 2,2′-bipyridine]
    Andréa P. Carnizello, Marília I.F. Barbosa, Monize Martins, Natália Helen Ferreira, Pollyanna F. Oliveira, Geórgia Modé Magalhães, Alzir Azevedo Batista, Denise Crispim Tavares · 2016 · Journal of Inorganic Biochemistry
75. MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species
    Olga Vera, Carlos Rodríguez‐Antolín, Ana Salgado-Figueroa, Patrycja Michalska, Olga Pernía, Brett M. Reid, Rocío Rosas, Álvaro García-Guede, Silvia Sacristán, Julia Jiménez et al. · 2018 · Translational research
76. In vitro and in vivo anti-tumor activity of two gold(III) complexes with isoquinoline derivatives as ligands
    Taj-Malook Khan, Noor Shad Gul, Xing Lü, Jian-Hua Wei, Yan-Cheng Liu, Hongbin Sun, Hong Liang, Chris Orvig, Zhen‐Feng Chen · 2018 · European Journal of Medicinal Chemistry
77. LncRNA MST1P2/miR‐133b axis affects the chemoresistance of bladder cancer to cisplatin‐based therapy via Sirt1/p53 signaling
    Jia Chen, Yuanwei Li, Zhiqiu Li, Lin Cao · 2020 · Journal of Biochemical and Molecular Toxicology
78. RETRACTED: TRIM59 knockdown blocks cisplatin resistance in A549/DDP cells through regulating PTEN/AKT/HK2
    Rong Qiao He, Hongxu Liu · 2020 · Gene · Retracted
79. Cisplatin Prodrug-Loaded Nanoparticles Based on Physalis Mottle Virus for Cancer Therapy
    He Hu, Nicole F. Steinmetz · 2020 · Molecular Pharmaceutics
80. A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms
    Bernadett Szikriszt, Ádám Póti, Eszter Németh, Nnennaya Kanu, Charles Swanton, Dávid Szüts · 2021 · Mutagenesis
81. Synthesis, characterization and anticancer activity of Fe(II) and Fe(III) complexes containing N-(8-quinolyl)salicylaldimine Schiff base ligands
    Sutthida Wongsuwan, Jaruwan Chatwichien, Bussaba Pinchaipat, Sarawut Kumphune, David J. Harding, Phimphaka Harding, Jaursup Boonmak, Sujittra Youngme, Ratanon Chotima · 2021 · JBIC Journal of Biological Inorganic Chemistry
82. 1,3‐Diazepine: A privileged scaffold in medicinal chemistry
    Yohan Malki, Jean Martínez, Nicolas Masurier · 2021 · Medicinal Research Reviews
83. Metal-coordinated nanomedicine for combined tumor therapy by inducing paraptosis and apoptosis
    Rongrong Zheng, Linping Zhao, Xiayun Chen, Lingshan Liu, Yibin Liu, Xiantong Chen, Chang Wang, Xiyong Yu, Hong Bo Cheng, Shiying Li · 2021 · Journal of Controlled Release
84. Cisplatin induces lung cell cilia disruption and lung damage via oxidative stress
    Yong Kwon Han, Ji Su Kim, GiBong Jang, Kwon Moo Park · 2021 · Free Radical Biology and Medicine
85. Norspermidine and Novel Pd(II) and Pt(II) Polynuclear Complexes of Norspermidine as Potential Antineoplastic Agents Against Breast Cancer
    Tânia Magalhães Silva, Sara Andersson, Sunil Kumar Sukumaran, Maria Paula M. Marques, Lo Persson, Stina Oredsson · 2013 · PLoS ONE
86. Clinical and molecular features in patients with advanced non-small-cell lung carcinoma refractory to first-line platinum-based chemotherapy
    Etienne Giroux Leprieur, Martine Antoine, Thibault Vieira, M. Duruisseaux, Virginie Poulot, Nathalie Rabbe, Laure Belmont, Valérie Gounant, A. Lavolé, Bernard J. Milleron et al. · 2012 · Lung Cancer
87. Advances in platinum-based cancer therapy: overcoming platinum resistance through rational combinatorial strategies
    Yusoh, Nur Aininie, Ahmad, Haslina, Vallis, Katherine A., Gill, Martin R. · 2025 · Medical Oncology
88. TFEB Regulates ATP7B Expression to Promote Platinum Chemoresistance in Human Ovarian Cancer Cells
    Raffaella Petruzzelli, Marta Mariniello, Rossella De Cegli, Federico Catalano, Floriana Guida, Elia Di Schiavi, Roman Polishchuk · 2022 · Cells
89. Strategies for the development of stimuli-responsive small molecule prodrugs for cancer treatment
    Yuxuan Tu, Jianbao Gong, Jing Mou, Hongfei Jiang, Haibo Zhao, Jiake Gao · 2024 · Frontiers in Pharmacology
90. Circ_0008315 promotes tumorigenesis and cisplatin resistance and acts as a nanotherapeutic target in gastric cancer
    Yao Fei, Danping Cao, Yanna Li, Zhixiong Wang, Runyu Dong, Menglin Zhu, Peng Gao, Xiaoming Wang, Juan Cai, Xueliang Zuo · 2024 · Journal of Nanobiotechnology
91. Anti-tumour activity of two novel compounds in cisplatin-resistant testicular germ cell cancer
    Bianca Nitzsche, C Gloesenkamp, M. Schrader, Björn Hoffmann, Friedemann Zengerling, Stefan Balabanov, Friedemann U. Honecker, Michael Höpfner · 2012 · British Journal of Cancer
92. Upregulation of endogenous ICAM‐1 reduces ovarian cancer cell growth in the absence of immune cells
    Marloes L. de Groote, Hinke G. Kazemier, Christian Huisman, Bernardina T.F. van der Gun, Marijke M. Faas, Marianne G. Rots · 2013 · International Journal of Cancer
93. Phospholipid-chitosan hybrid nanoliposomes promoting cell entry for drug delivery against cervical cancer
    Somsak Saesoo, Suphawadee Bunthot, Warayuth Sajomsang, Pattarapond Gonil, Sarunya Phunpee, Patsaya Songkhum, Kritapas Laohhasurayotin, Tuksadon Wutikhun, Teerapong Yata, Uracha Ruktanonchai et al. · 2016 · Journal of Colloid and Interface Science
94. MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1
    Hui Liu, Xinhua Cheng · 2018 · Oncotarget
95. Synthesis, characterization and anticancer studies of bis-(N-methyl-1-phenyldithiocarbamato) Cu(II), Zn(II), and Pt(II) complexes: single crystal X-ray structure of the copper complex
    Fartisincha P. Andrew, Peter Adewale Ajibade · 2018 · Journal of Coordination Chemistry
96. Molecular Mechanisms of Cisplatin Chemoresistance and Its Circumventing in Testicular Germ Cell Tumors
    Silvia Schmidtova, Katarína Kaľavská, Lucia Kučerová · 2018 · Current Oncology Reports
97. Expanding the Chemical Space of Withaferin A by Incorporating Silicon To Improve Its Clinical Potential on Human Ovarian Carcinoma Cells
    Nayra R. Perestelo, Gabriel G. Llanos, Carolina P. Reyes, Ángel Amesty, Kartheek Sooda, Saeed Afshinjavid, Ignacio A. Jiménez, Farideh A. Javid, Isabel L. Bazzocchi · 2019 · Journal of Medicinal Chemistry
98. Upregulation of MDR- and EMT-Related Molecules in Cisplatin-Resistant Human Oral Squamous Cell Carcinoma Cell Lines
    Hyeong Sim Choi, Young‐Kyun Kim, Pil‐Young Yun · 2019 · International Journal of Molecular Sciences
99. Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers
    Bradley Allen Hancock, Yu-Hsiang Chen, Jeffrey P. Solzak, Mufti Naeem Ahmad, David C. Wedge, Dumitru Brinza, Charles Scafe, James M Veitch, Rajesh Gottimukkala, Walt Short et al. · 2019 · Breast Cancer Research
100. Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer
     Ki Hong Nam, Sang Ah Yi, Gibeom Nam, Jae Sung Noh, Jong Woo Park, Min Gyu Lee, Jee Hun Park, Hwamok Oh, Jieun Lee, Kang Ro Lee et al. · 2019 · BMC Cancer