Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Wang, P, Dong, Q, Zhang, C, Kuan, P-F, Liu, Y, Jeck, W R, Andersen, J B, Jiang, W +18 more·2013·Oncogene

Cited by (398)

Items 101–200 of 398

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    Xiang, Xiao, Liu, Ziyang, Zhang, Chong, Li, Zhao, Gao, Jie, Zhang, Changkun, Cao, Qi, Cheng, Jinghui, Liu, Hengkang, Chen, Dingbao et al. · 2021 · Advanced Science
  2. IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas
    Arjen H.G. Cleven, Johnny Suijker, Georgios Agrogiannis, Inge H. Briaire‐de Bruijn, Norma Frizzell, Attje S. Hoekstra, Pauline M. Wijers‐Koster, Anne‐Marie Cleton-Jansen, Judith V.M.G. Bovée · 2017 · Clinical Sarcoma Research
  3. Intrahepatic cholangiocarcinoma: current management and emerging therapies
    Amir Ata Rahnemai‐Azar, Allison B. Weisbrod, Mary E. Dillhoff, Carl Richard Schmidt, Timothy Michael Pawlik · 2017 · Expert Review of Gastroenterology & Hepatology
  4. A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary
    Alicia‐Marie Conway, Simon P. Pearce, Alexandra Clipson, Steven M. Hill, Francesca Chemi, Daniel Slane-Tan, Saba Ferdous, Arman Hossain, Katarzyna Kamieniecka, Daniel J. White et al. · 2024 · Nature Communications
  5. Specific monoclonal antibodies against IDH1/2 mutations as diagnostic tools for gliomas
    Yukinari Kato · 2014 · Brain Tumor Pathology
  6. Isocitrate dehydrogenase variants in cancer — Cellular consequences and therapeutic opportunities
    Shuang Liu, Tom A.D. Cadoux-Hudson, Christopher John Schofield · 2020 · Current Opinion in Chemical Biology
  7. Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link
    Chaobo Chen, Leonard J. Nelson, Matias Antonio Avila, Francisco Javier Cubero · 2019 · Cells
  8. Molecular pathogenesis of intrahepatic cholangiocarcinoma
    Jesper Bøje Andersen · 2014 · Journal of Hepato-Biliary-Pancreatic Sciences
  9. Global DNA methylation and hydroxymethylation differ in hepatocellular carcinoma and cholangiocarcinoma and relate to survival rate
    Silvia Udali, Patrizia Guarini, Sara Moruzzi, Andrea Ruzzenente, Stephanie A. Tammen, Alfredo Guglielmi, Simone Conci, Patrizia Pattini, Oliviero Olivieri, Roberto Corrocher et al. · 2015 · Hepatology
  10. Biliary cancer: intrahepatic cholangiocarcinoma vs. extrahepatic cholangiocarcinoma vs. gallbladder cancers: classification and therapeutic implications
    Daniel H. Ahn, Tanios Bekaii‐Saab · 2017 · Journal of Gastrointestinal Oncology
  11. IDH Mutations in Tumorigenesis and Their Potential Role As Novel Therapeutic Targets
    Daniel Krell, Paul James Mulholland, Adam Enver Frampton, Jonathan Krell, Justin Stebbing, Chiara Bardella · 2013 · Future Oncology
  12. Cell-free DNA from bile outperformed plasma as a potential alternative to tissue biopsy in biliary tract cancer
    Qing Gou, C.Z. Zhang, Zhanguo Sun, Lei Wu, Y. Chen, Zhanjie Mo, Qicong Mai, Jian He, Zhigang Zhou, F. Shi et al. · 2021 · ESMO Open
  13. Cholangiocarcinoma: risk factors, environmental influences and oncogenesis.
    Redha Al-Bahrani, Yasser Abuetabh, Nikolas Zeitouni, Consolato Maria Sergi · 2013 · PubMed
  14. New developments in systemic therapy for advanced biliary tract cancer
    Chigusa Morizane, Makoto Ueno, Masafumi Ikeda, Takuji Okusaka, Hiroshi Ishii, Junji Furuse · 2018 · Japanese Journal of Clinical Oncology
  15. SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
    Xiaomin Wang, Ziqi Chen, Jun Xu, Shuai Tang, Nan An, Lei Jiang, Yixiang Zhang, Shaoying Zhang, Qingli Zhang, Yanyan Shen et al. · 2022 · Cell Research
  16. The potential role of comprehensive genomic profiling to guide targeted therapy for patients with biliary cancer
    Hwajeong Lee, Jeffrey S. Ross · 2017 · Therapeutic Advances in Gastroenterology
  17. Genetics of Opisthorchis viverrini-related cholangiocarcinoma
    Apinya Jusakul, Sarinya Kongpetch, Bin Tean Teh · 2015 · Current Opinion in Gastroenterology
  18. Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype
    Elisabet Cuyàs, Salvador Fernández‐Arroyo, Bruna Corominas-Faja, Esther Rodríguez‐Gallego, Joaquim Bosch‐Barrera, Begoña Martı́n-Castillo, Rafel Llorens, Jorge Joven, Javier Abel Menéndez · 2015 · Oncotarget
  19. Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG
    Anna Catharina Navis, Simone P. Niclou, Fred Fack, Daniel Stieber, Sanne A. M. van Lith, Kiek N. Verrijp, Alan J. Wright, Jonathan Stauber, Bastiaan B.J. Tops, Irene Otte‐Höller et al. · 2013 · Acta Neuropathologica Communications
  20. High-throughput mutation profiling identifies novel molecular dysregulation in high-grade intraepithelial neoplasia and early gastric cancers
    Matteo Fassan, Michele Simbolo, Emilio Bria, Andrea Mafficini, Sara Pilotto, Paola Capelli, Maria Bencivenga, Sara Pecori, Claudio Luchini, Diogo Neves et al. · 2013 · Gastric Cancer
  21. Fibroblast growth factor receptor 2 fusions as a target for treating cholangiocarcinoma
    Mitesh J. Borad, Gregory James Gores, Lewis Rowland Roberts · 2015 · Current Opinion in Gastroenterology
  22. 5-Hydroxymethylcytosine Profiling as an Indicator of Cellular State
    Alexander Laird, John P. Thomson, David James Harrison, Richard R. Meehan · 2013 · Epigenomics
  23. Intrahepatic cholangiocarcinoma: Morpho-molecular pathology, tumor reactive microenvironment, and malignant progression
    Alphonse Eugene Sirica, Mario Strazzabosco, Massimiliano Cadamuro · 2020 · Advances in cancer research
  24. Systemic treatment of advanced or recurrent biliary tract cancer
    Wei Zhang, Hongyuan Zhou, Yingying Wang, Zewu Zhang, Guangtai Cao, Tianqiang Song, Ti Zhang, Qiang Li · 2020 · BioScience Trends
  25. Metabolic adaptations in cancers expressing isocitrate dehydrogenase mutations
    Ingvild Comfort Hvinden, Tom A.D. Cadoux-Hudson, Christopher John Schofield, James McCullagh · 2021 · Cell Reports Medicine
  26. Mutant IDH in Gliomas: Role in Cancer and Treatment Options
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  27. Molecular docking and molecular dynamics studies reveal structural basis of inhibition and selectivity of inhibitors EGCG and OSU-03012 toward glucose regulated protein-78 (GRP78) overexpressed in glioblastoma
    Rituparna Bhattacharjee, Arpita Devi, Seema Mishra · 2015 · Journal of Molecular Modeling
  28. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth
    Shenghong Ma, Bowen Jiang, Wanglong Deng, Zhong-Kai Gu, Fei-Zhen Wu, Tingting Li, Yukun Xia, Hui Yang, Dan Ye, Yue Xiong et al. · 2015 · Oncotarget
  29. Maffucci syndrome and neoplasms: a case report and review of the literature
    Olga Prokopchuk, Stephanie Andres, Karen Becker, Konstantin Holzapfel, Daniel Hartmann, Helmut Frieß · 2016 · BMC Research Notes
  30. Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma
    Alexandra R. Grassian, Raymond A. Pagliarini, Derek Y. Chiang · 2014 · Current Opinion in Gastroenterology
  31. The immune milieu of cholangiocarcinoma: From molecular pathogenesis to precision medicine
    Lorenza Rimassa, Nicola Personeni, Alessio Aghemo, Ana Lleò · 2019 · Journal of Autoimmunity
  32. Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities
    Xiangyu Wang, Wenwei Zhu, Zheng Wang, Jian-Bo Huang, Shenghao Wang, Fumao Bai, Tian‐En Li, Ying Zhu, Jing Zhao, Xin Yang et al. · 2021 · Theranostics
  33. IDH1, a CHOP and C/EBPβ-responsive gene under ER stress, sensitizes human melanoma cells to hypoxia-induced apoptosis
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  34. Proximity ligation assay evaluates IDH1R132H presentation in gliomas
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  35. TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine
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  36. Functional and topographic effects on DNA methylation in IDH1/2 mutant cancers
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  42. Cholangiocarcinoma 2020: the next horizon in mechanisms and management
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  43. Novel targeted treatment options for advanced cholangiocarcinoma
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  45. Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways
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  47. The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo
    Johnny Suijker, Hans J. Baelde, Helene Roelofs, Anne‐Marie Cleton-Jansen, Judith V.M.G. Bovée · 2015 · Oncotarget
  48. Biliary Tract Cancers: Molecular Heterogeneity and New Treatment Options
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  49. Molecular characteristics of biliary tract cancer
    Davendra P. S. Sohal, Shiva Shrotriya, Mohamed E. Abazeed, Michael W. Cruise, Alok A. Khorana · 2016 · Critical Reviews in Oncology/Hematology
  50. Otto Warburg: The journey towards the seminal discovery of tumor cell bioenergetic reprogramming
    Ana M. Urbano · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  51. IDH mutations in liver cell plasticity and biliary cancer
    Supriya K. Saha, Christine A. Parachoniak, Nabeel M. Bardeesy · 2014 · Cell Cycle
  52. Current biologics for treatment of biliary tract cancers
    Diana Yi Zhao, Kian‐Huat Lim · 2017 · Journal of Gastrointestinal Oncology
  53. Reporting Tumor Molecular Heterogeneity in Histopathological Diagnosis
    Andrea Mafficini, Eliana Amato, Matteo Fassan, Michele Simbolo, Davide Antonello, Caterina Vicentini, Maria Scardoni, Samantha Bersani, Marisa Gottardi, Borislav Chavdarov Rusev et al. · 2014 · PLoS ONE
  54. Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro
    Shawn M. Sarkaria, Matthew J Christopher, Jeffery M. Klco, Timothy James Ley · 2014 · Leukemia
  55. L2hgdh Deficiency Accumulates l -2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration
    Shenghong Ma, Renqiang Sun, Bowen Jiang, Jun Gao, Wanglong Deng, Peng Liu, Ruoyu He, Jing Cui, Minbiao Ji, Wei Yi et al. · 2017 · Molecular and Cellular Biology
  56. Molecular Targets in Cholangiocarcinoma
    Colm J. O’Rourke, Patricia Muñoz-Garrido, Jesper Bøje Andersen · 2020 · Hepatology
  57. Molecular Pathogenesis of Cholangiocarcinoma
    Sumera H. Rizvi, Gregory James Gores · 2014 · Digestive Diseases
  58. IDH1, lipid metabolism and cancer: Shedding new light on old ideas
    Elena Bogdanovic · 2015 · Biochimica et Biophysica Acta (BBA) - General Subjects
  59. Quality and performance of validated prognostic models for survival after resection of intrahepatic cholangiocarcinoma: a systematic review and meta-analysis
    Stefan Buettner, Boris Galjart, Berend R. Beumer, Jeroen L.A. van Vugt, Casper H.J. van Eijck, Wojciech Grzegorz Polak, Jeroen de Jonge, Marjolein Y.V. Homs, Lydi M.J.W. van Driel, Timothy Michael Pawlik et al. · 2020 · HPB
  60. Emerging molecular targets and therapy for cholangiocarcinoma
    Hamzeh Kayhanian, Elizabeth Catherine Smyth, Chiara Braconi · 2017 · World Journal of Gastrointestinal Oncology
  61. PARP Inhibitors in Biliary Tract Cancer: A New Kid on the Block?
    Angela Dalia Ricci, Alessandro Rizzo, Chiara Bonucci, Nastassja Tober, Andrea Palloni, Veronica Mollica, Ilaria Maggio, Marzia Deserti, Simona Tavolari, Giovanni Brandi · 2020 · Medicines
  62. Future directions in the treatment of cholangiocarcinoma
    Andrew Xiuxuan Zhu · 2015 · Best Practice & Research Clinical Gastroenterology
  63. Clinicopathological, radiologic, and molecular study of 23 combined hepatocellular-cholangiocarcinomas with stem cell features, cholangiolocellular type
    Jun Chen, Jian He, Min Deng, Hongyan Wu, Jiong Shi, Liang Mao, Qi Sun, Min Tang, Xiangshan Fan, Yudong Qiu et al. · 2017 · Human Pathology
  64. Circulating oncometabolite D-2-hydroxyglutarate enantiomer is a surrogate marker of isocitrate dehydrogenase–mutated intrahepatic cholangiocarcinomas
    J Delahousse, Loïc Verlingue, Sophie Broutin, Clémence Legoupil, Mehdi Touat, Ludovic S. Doucet, Samy Ammari, Ludovic Lacroix, Michel Pierre Ducreux, Jean‐Yves Scoazec et al. · 2018 · European Journal of Cancer
  65. Therapy for advanced cholangiocarcinoma: Current knowledge and future potential
    Mingxun Wang, Ziyan Chen, Pengyi Guo, Yi Wang, Gang Chen · 2020 · Journal of Cellular and Molecular Medicine
  66. Clinical Efficacy of Olaparib in IDH1/IDH2- Mutant Mesenchymal Sarcomas
    Joseph P. Eder, Deborah B. Doroshow, Khanh T Do, Vicki Leigh Keedy, Jeffrey Sklar, Peter M. Glazer, Ranjit S. Bindra, Geoffrey Ira Shapiro · 2021 · JCO Precision Oncology
  67. Epigenetic reduction of DNA repair in progression to gastrointestinal cancer
    Carol Bernstein · 2015 · World Journal of Gastrointestinal Oncology
  68. Genomic alterations in cholangiocarcinoma: clinical significance and relevance to therapy
    Marianeve Carotenuto, Alessandra Sacco, Laura Forgione, Nicola Normanno · 2022 · Exploration of Targeted Anti-tumor Therapy
  69. IDH1‐mutant cancer cells are sensitive to cisplatin and an IDH1‐mutant inhibitor counteracts this sensitivity
    Mohammed Khurshed, Niels Aarnoudse, Renske Hulsbos, Vashendriya V.V. Hira, Hanneke W.M. van Laarhoven, Johanna W. Wilmink, Remco Jurriaan Molenaar, Cornelis J.F. Van Noorden · 2018 · The FASEB Journal
  70. Role of 5-hydroxymethylcytosine level in diagnosis and prognosis prediction of intrahepatic cholangiocarcinoma
    Zhao‐Ru Dong, Chi Zhang, Jiabin Cai, Pengfei Zhang, Guo‐Ming Shi, Dongmei Gao, Hui‐Chuan Sun, Shuang–Jian Qiu, Jian Zhou, Ai‐Wu Ke et al. · 2014 · Tumor Biology
  71. Genetic profiling of intrahepatic cholangiocarcinoma and its clinical implication in targeted therapy.
    Diyang Xie, Zhenggang Ren, Jia Fan, Qiang Gao · 2016 · PubMed Central
  72. Is the IDH Mutation a Good Target for Chondrosarcoma Treatment?
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  73. Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors
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  74. Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma
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  75. Matching genomic molecular aberrations with molecular targeted agents: Are biliary tract cancers an ideal playground?
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  76. Emerging role of precision medicine in biliary tract cancers
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  77. Valproic Acid Enhanced Temozolomide-Induced Anticancer Activity in Human Glioma Through the p53–PUMA Apoptosis Pathway
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  78. Innovative Medicine
    Kazuwa Nakao, Nagahiro Minato, Shinji Üemoto · 2015 · Springer eBooks
  79. Update on cholangiocarcinoma: potential impact of genomic studies on clinical management
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  80. Broadening the therapeutic horizon of advanced biliary tract cancer through molecular characterisation
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    Jung Hee Lee, Dong‐Hoon Shin, Won Young Park, Nari Shin, Ahrong Kim, Hyun Jung Lee, Young Keum Kim, Kyung Un Choi, Jee Yeon Kim, Young Il Yang et al. · 2017 · World Journal of Surgical Oncology
  85. Molecular perturbations in cholangiocarcinoma: Is it time for precision medicine?
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  86. R-2HG downregulates ERα to inhibit cholangiocarcinoma via the FTO/m6A-methylated ERα/miR16-5p/YAP1 signal pathway
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  87. Prognostic impact of FGFR2/3 alterations in patients with biliary tract cancers receiving systemic chemotherapy: the BITCOIN study
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  88. Epidemiology, biology, and management of venous thromboembolism in gliomas: An interdisciplinary review
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  90. Targeting FGFR in intrahepatic cholangiocarcinoma [iCCA]: leading the way for precision medicine in biliary tract cancer [BTC]?
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  91. Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies
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  92. Sirtuin activation targets IDH-mutant tumors
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    Roberto Gutierrez, Timothy R O'Connor · 2021 · Cancer Drug Resistance
  94. Molecular diagnosis of intrahepatic cholangiocarcinoma
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