CDK6—a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation
Tigan, A-S, Bellutti, F, Kollmann, K, Tebb, G, Sexl, V·2016·Oncogene
Cited by (206)
Items 101–200 of 206
- CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomasYiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang · 2020 · International Journal of Molecular Medicine
- Cyclin-dependent kinase inhibition: an opportunity to target protein-protein interactionsMark Alan Klein · 2019 · Advances in protein chemistry and structural biology
- The Effect of CDK6 Expression on DNA Methylation and DNMT3B RegulationGerwin Heller, Sofie Nebenfuehr, Florian Bellutti, Huriye Ünal, Markus Zojer, Lisa Scheiblecker, Veronika Sexl, Karoline Kollmann · 2020 · iScience
- The driving power of the cell cycle: cyclin-dependent kinases, cyclins and their inhibitorsMárk Híveš, Jana Jurečeková, KLAUDIA HÍVEŠ HOLEČKOVÁ, Jan Kliment, Monika Kmeťová Sivoňová · 2023 · Bratislavské lekárske listy/Bratislava medical journal
- Progression after First-Line Cyclin-Dependent Kinase 4/6 Inhibitor Treatment: Analysis of Molecular Mechanisms and Clinical DataFederica Villa, Alessandra Crippa, Davide Pelizzoni, Alessandra Ardizzoia, Giulia Scartabellati, Cristina Corbetta, Eleonora Cipriani, Marialuisa Lavitrano, Antonio Ardizzoia · 2023 · International Journal of Molecular Sciences
- A robust approach for the generation of functional hematopoietic progenitor cell lines to model leukemic transformationEszter Doma, Isabella Maria Mayer, Tania Brandstoetter, Barbara Maurer, Reinhard Grausenburger, Ingeborg Menzl, Markus Zojer, Andrea Hoelbl‐Kovacic, Leif Carlsson, Gerwin Heller et al. · 2020 · Blood Advances
- A C/ebpα isoform specific differentiation program in immortalized myelocytesMaría-Paz García-Cuéllar, Selin Akan, Robert K. Slany · 2023 · Leukemia
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- Control of the Cell CycleMarcos Malumbres · 2020 · Elsevier eBooks
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- Dysregulation of miR-1-3p: An Early Event in Colitis-Associated DysplasiaMariana Franco Fragoso, Geysson Javier Fernández, Lisa Vanderveer, Harry S. Cooper, Michael J. Slifker, Margie L. Clapper · 2022 · International Journal of Molecular Sciences
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- Single-cell cloning of human T-cell lines reveals clonal variation in cell death responses to chemotherapeuticsKathleen M. Hanlon, Alex Thompson, Lorena Pantano, John N. Hutchinson, Arshed Al‐Obeidi, Shu Wang, Meghan Bliss‐Moreau, Jennifer D. Helble, Gabriela Alexe, Kimberly Stegmaier et al. · 2019 · Cancer Genetics
- CDK6 is stimulated by hyperthermia and protects gastric cancer cells from hyperthermia‑induced damageGuanghui Liu, Hongchao Zhao, Qingqing Ding, Haohao Li, Tao Liu, Hongwei Yang, Yuanhua Liu · 2021 · Molecular Medicine Reports
- In silico Drug Repurposing of FDA-Approved Artemisinins as Potent Chemotherapeutics Targeting Bcl-2, CDK-6 & VEGFR-2: Density Functional Exploration and Molecular Docking Study2020 · Biointerface Research in Applied Chemistry
- Advances in Cutaneous Melanoma Therapy: The Emerging Role of CDK4/6 InhibitorsUriel Kim, Thomas S. McCormick, Ankit Mangla, Kevin D. Cooper, Gary K. Schwartz, Akihiro Yoshida · 2025 · Pharmacological Research
- Identification and Functional Analysis of the G1 Phase Cyclin Dependent Kinase Gene Hc-CDK6 in Pearl Mussels (Hyriopsis cumingii)Shangle Feng, XueNan Li, He Wang, Wenjuan Li, Zhiyi Bai · 2022 · Frontiers in Marine Science
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- Dual targeting of CDK6 and LSD1 is synergistic and overcomes differentiation blockade in AMLLise M. Brault, Edwige Voisset, Mathieu Desaunay, Antonia Boudet, Paraskevi Kousteridou, Sébastien Letard, Nadine Carbuccia, Armelle Goubard, Rémy Castellano, Yves Collette et al. · 2025 · EMBO Molecular Medicine
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- Anticancer, anti-inflammatory, and immune modulatory activity of ferulic acid fructo-oligosaccharide conjugated microparticleEldin Maliyakkal Johnson, R. Jayabalan, Samir Kumar Patra, Joo‐Won Suh · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cellsAdriana K. Alexander, Karina F. Rodriguez, Yuying Chen, Ciro Maurizio Amato, Martin Andres Estermann, Xin Miao Xu, Humphrey Hung‐Chang Yao · 2024 · eLife
- Single-nucleus multiomics reveals the gene regulatory networks underlying sex determination of murine primordial germ cellsAdriana K. Alexander, Karina F. Rodriguez, Yuying Chen, Ciro Maurizio Amato, Martin Andres Estermann, Barbara Nicol, Xin Xu, Humphrey Hung‐Chang Yao · 2024 · eLife
- Cdk6’s functions are critically regulated by its unique C-terminusAlessia Schirripa, Helge Schöppe, Sofie Nebenfuehr, Markus Zojer, Thorsten Klampfl, Valentina Kugler, Belinda S. Schmalzbauer, Huriye Ceylan, Iris Z. Uras, Lisa Scheiblecker et al. · 2024 · iScience
- BET Bromodomain Inhibition Reverses CDK4/6 Inhibitor Resistance in Estrogen Receptor–Positive Breast Cancer via Induction of miR-34a-5pRenyan Liu, Xin Wang, Timothy B. Branigan, Daryl Griffin, Caoibhne McSweeney, Jie Hao, Constantia Pantelidou, Zachary T. Herbert, Heta Jadhav, Geoffrey Ira Shapiro · 2025 · Clinical Cancer Research
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- Cell-cycle targeted cancer therapy: clinical advances, biological gaps, and the emergence of selective CDK4 inhibitorsAva Safaroghli‐Azar, Laychiluh Bantie Mekonnen, Jimma Likisa Lenjisa, Robert W. Milne, Shudong Wang · 2026 · Journal of Hematology & Oncology
- Advantages of PROTACs in achieving selective degradation of homologous protein familiesLuxi Yang, Xinfei Mao, Jingyi Zhang, Jing Shu, Wenhai Huang, Xiaowu Dong, Yinqiao Chen, Mingfei Wu · 2026 · Beilstein Journal of Organic Chemistry
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- Molecular characterization of the cyclin-dependent protein kinase 6 in whitefish (Coregonus lavaretus) and its potential interplay with miR-34aAlicja Łakomiak, Paweł Brzuzan, EWA JAKIMIUK, Maciej Florczyk, Maciej Woźny · 2019 · Gene
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- A robust platform for BaEVRless-lentiviral synthesis and primary natural killer cell transductionYi-Jun Lan, Quoc Viet Nguyen, Tsu-Lan Chao, Kuo-Lun Yeh, Steven Lin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Structural requirements for the specific binding of CRABP2 to cyclin D3Martyna W. Pastok, Charles W.E. Tomlinson, Shannon Turberville, Abbey M. Butler, Arnaud Baslé, Martin E. M. Noble, Jane Endicott, Ehmke Pohl, Natalie J. Tatum · 2024 · Structure
- Genetic analysis in a consanguineous MCPH family revealed a refinement of the MCPH12 locus and a founder effect of the recurrent CDK6 variant [c.589G>A, p.(Ala197Thr)] in the Pakistani populationMuzammil Ahmad Khan, Jasmin Blatterer, Markus Kuster, Lukas Kaufmann, Peter M. Kroisel, John B. Vincent, Muhammad Zubair, Muhammad Muzammal, Nisar Ahmad, Shakil Abbas et al. · 2025 · Journal of Genetics
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- Silencing of DHX32 increases the proliferation of liver cancer cellsMinjing Cai, Jianhui Zhu, Jianquan He, Zhongying Zhang, Xianming Liang · 2020 · Translational Cancer Research
- CDK6 Immunophenotype Implicates Potential Therapeutic Application of CDK4/6 Inhibitors in Urothelial CarcinomaRan Sun, Xuemei Wang, Leichao Zhang, Yu Gu, Shaojuan Yang, Liping Wang, Xueju Wang · 2022 · Frontiers in Oncology
- Vasopressin Receptors in Blood Vessels and Proliferation of EndotheliocytesIgor I. Khegay · 2021 · Russian Journal of Bioorganic Chemistry
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- Expression of the CXCR4 S338X Variant Improves Anti‐Leukemia Efficacy of Anti‐ CD19 CAR ‐T CellsYushu Mao, Xiaodan Wang, Chunhui Jin, Zhifeng Wei, Qing Ding, Ke‐Ke Zhang, Bo‐Wen Dong, K. Zheng, Yufei Hou, Tao Zhang et al. · 2025 · Cancer Science
- Microneedle–peptide biosensor platform for multiplexed profiling of cyclin-dependent kinase activities in cancer cell linesChloé Royet, Lennard Lecki, Sébastien Diot, Saïd Jebors, Karine Puget, Sanjiv Sharma, May Catherine Morris · 2026 · Sensors and Actuators Reports
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- Clinical implementation of biomarkers and signaling pathway as novel targeted therapeutics in breast cancerRama Kadamb, Saurabh Singh · 2023 · Elsevier eBooks
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- A cutting-edge approach unravels a novel role for CDK6 in leukemic progenitor cellsEszter Doma, Isabella Maria Mayer, Tania Brandstoetter, Barbara Maurer, Reinhard Grausenburger, Ingeborg Menzl, Markus Zojer, Andrea Hoelbl‐Kovacic, Leif Carlsson, Gerwin Heller et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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- Targeting MDM2, the antagonist of the tumor suppressor p53Anusha Sriraman · 2018
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- Loss of Leiomodin1 Enhances Smooth Muscle Cell Proliferation and Neointima FormationSara A. Wennersten, Hongxia Wang, J. Lee Franklin, Vivek Nanda · 2025 · SSRN Electronic Journal
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- Additional file 1 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 3 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 7 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 2 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 4 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 4 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 5 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 6 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 6 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 1 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 7 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Jianye Zhang, Fang, Shuo · 2022 · Figshare
- Additional file 8 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 8 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 5 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 9 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 10 of CDK6 is upregulated and may be a potential therapeutic target in enzalutamide-resistant castration-resistant prostate cancerChen, Xi, Wu, Yechen, Wang, Xinan, Chengdang Xu, Wang, Licheng, Jingang Jian, Wu, Denglong, Gang Wu · 2022 · Figshare
- Additional file 3 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
- Additional file 2 of CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cellsZhang, Lei, Li, Yidong, Hu, Chaohua, Yangmin Chen, Chen, Zhuo, Chen, Zhe-Sheng, Zhang, Jian-Ye, Fang, Shuo · 2022 · Figshare
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