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The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Dual inhibition of JAK1/2 kinases and BCL2: a promising therapeutic strategy for acute myeloid leukemia

Kurtz, Stephen E., Eide, Christopher A., Kaempf, Andy, Mori, Motomi, Tognon, Cristina E., Borate, Uma, Druker, Brian J., Tyner, Jeffrey W.·2018·Leukemia
DOI 10.1038/s41375-018-0225-7PMC PMC6168939
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Citations

Cites

Research works printed but not linked: 14

  1. Dohner H, Weisdorf DJ, Bloomfield CD. Acute myeloid leukemia. N Engl J Med. 2015;373:1136–52. · DOI
  2. Medeiros BC, Satram-Hoang S, Hurst D, Hoang KQ, Momin F, Reyes C. Big data analysis of treatment patterns and outcomes among elderly acute myeloid leukemia patients in the United States. Ann Hematol. 2015;94:1127–38. · DOI
  3. Kurtz SE, Eide CA, Kaempf A, Khganna V, Savage SL, Rofelty A, et al. Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies. Proc Natl Acad Sci USA. 2017;114:e7554–63. · DOI
  4. Ogama Y, Mineyama T, Yamamoto A, Woo M, Shimada N, Amagasaki T, et al. A randomized dose-escalation study to assess the safety, tolerability, and pharmacokinetics of ruxolitinib (INC424) in healthy Japanese volunteers. Int J Hematol. 2013;97:351–9. · DOI
  5. Roberts AW, Davids MS, Pagel JM, Kahl BS, Puvvada SD, Gerecitano JF, et al. Targeting BCL2 with venetoclax in relapsed chronic lymphocytic leukemia. N Engl J Med. 2016;374:311–22. · DOI
  6. TCGA. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med. 2013;368:2059–74. · DOI · Paper page
  7. Karjalainen R, Pemovska T, Popa M, Liu M, Javarappa KK, Majumder MM, et al. JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML. Blood. 2017;130:789–802. · DOI
  8. Senkevitch E, Li W, Hixon JA, Andrews C, Cramer SD, Pauly GT, et al. Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Ralpha mutations. Oncotarget. 2018;9:22605–17. · DOI
  9. DiNardo CD, Pratz KW, Letai A, Jonas BA, Wei AH, Thirman M, et al. Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study. Lancet Oncol. 2018;19:216–28. · DOI
  10. Zhang M, Mathew Griner LA, Ju W, Dubeau DY, Guha R, Petrus MN, et al. Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia. Proc Natl Acad Sci USA. 2015;112:12480–5. · DOI
  11. Waibel M, Solomon VS, Knight DA, Rallia RA, Kim SK, Banks KM, et al. Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors. Cell Rep. 2013;5:1047–59. · DOI
  12. Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res. 2002;8:945–54.
  13. Ertel F, Nguyen M, Roulston A, Shore GC. Programming cancer cells for high expression levels of Mcl1. EMBO Rep. 2013;14:328–36. · DOI
  14. Glaser SP, Lee EF, Trounson E, Bouillet P, Wei A, Fairlie WD, et al. Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. Genes Dev. 2012;26:120–5. · DOI

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Metadata

Authors
Kurtz, S. E., Eide, C. A., Kaempf, A., Mori, M., Tognon, C. E., Borate, U., Druker, B. J., & Tyner, J. W.
Venue
Leukemia
Publisher
Springer Science and Business Media LLC
Published
2018-08-06
Volume
32
Issue
9
Pages
2025-2028
ISSN
  • 0887-6924
  • 1476-5551
DOI
10.1038/s41375-018-0225-7
PMC
PMC6168939
Cited by
20
References
2
Language
en
Licence
www.springer.com/tdm (tdm)

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