Cited by 0Chronic Lymphocytic Leukemia ResearchAcute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

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Concordance between bone marrow and blood measurable residual disease after first-line novel agent treatment for chronic lymphocytic leukemia: a systematic review and meta-analysis

Fiorica, Giuseppe, Wehmeyer, Graham, Yee, Claire I., Segovia, Diana, Rios-Olais, Fausto Alfredo, Hilal, Talal, Kittai, Adam S.·2026·Leukemia

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References 8

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  1. Wang Y, Li C, Gale RP, Liang Q, Kay NE, Huang Q, et al. Measurable residual disease is not a universally reliable surrogate for progression-free survival in clinical trials of new chronic lymphocytic leukemia therapies. Leukemia. 2026;40:1439–47. · DOI
  2. Rios-Olais FA, McGary AK, Tsang M, Almader-Douglas D, Leis JF, Buras MR, et al. Measurable residual disease and clinical outcomes in chronic lymphocytic leukemia: a systematic review and meta-analysis. JAMA Oncol. 2024;10:1221–7. · DOI
  3. Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials. 2007;8:16. · DOI · Paper page
  4. Al-Sawaf O, Robrecht S, Zhang C, Olivieri S, Chang YM, Fink AM, et al. Venetoclax-obinutuzumab for previously untreated chronic lymphocytic leukemia: 6-year results of the randomized phase 3 CLL14 study. Blood. 2024;144:1924–35. · DOI
  5. Moreno C, Greil R, Demirkan F, Tedeschi A, Anz B, Larratt L, et al. First-line treatment of chronic lymphocytic leukemia with ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab: final analysis of the randomized, phase III iLLUMINATE trial. Haematologica. 2022;107:2108–20. · DOI
  6. Eichhorst B, Niemann CU, Kater AP, Furstenau M, von Tresckow J, Zhang C, et al. First-line venetoclax combinations in chronic lymphocytic leukemia. N Engl J Med. 2023;388:1739–54. · DOI
  7. Munir T, Moreno C, Owen C, Follows G, Benjamini O, Janssens A, et al. Impact of minimal residual disease on progression-free survival outcomes after fixed-duration ibrutinib-venetoclax versus chlorambucil-obinutuzumab in the GLOW study. J Clin Oncol. 2023;41:3689–99. · DOI
  8. Koo TK, Li MY. A guideline of selecting and reporting intraclass correlation coefficients for reliability research. J Chiropr Med. 2016;15:155–63. · DOI · Paper page

Metadata

Authors
Fiorica, G., Wehmeyer, G., Yee, C. I., Segovia, D., Rios-Olais, F. A., Hilal, T., & Kittai, A. S.
Affiliations
  • Icahn School of Medicine at Mount Sinai (US)
  • Tisch Cancer Institute (US)
  • Mayo Clinic in Arizona (US)
  • NYU Langone’s Laura and Isaac Perlmutter Cancer Center (US)
Corresponding author
Hilal, Talal
Venue
Leukemia
Published
2026-10-22
ISSN
  • 0887-6924 (ISSN-L)
  • 1476-5551
OpenAlex
W7223177333
Cited by
0
References
8
FWCI
0.00
Type
journal article
Language
en
Open access
closed
Locations
  • Leukemia (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Hematology › Chronic Lymphocytic Leukemia Research
  • Health Sciences › Medicine › Hematology › Acute Lymphoblastic Leukemia research
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Lymphoma Diagnosis and Treatment
Keywords
chronic lymphocytic leukemia, minimal residual disease, bone marrow, blood, concordance, first-line therapy, novel agents

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CoChat. (2026). Citation check: Concordance between bone marrow and blood measurable residual disease after first-line novel agent treatment for chronic lymphocytic leukemia: a systematic review and meta-analysis. https://app.cochat.ai/papers/10.1038/s41375-026-03178-9
The paper
Fiorica, G., Wehmeyer, G., Yee, C. I., Segovia, D., Rios-Olais, F. A., Hilal, T., & Kittai, A. S. (2026). Concordance between bone marrow and blood measurable residual disease after first-line novel agent treatment for chronic lymphocytic leukemia: a systematic review and meta-analysis. Leukemia. https://doi.org/10.1038/s41375-026-03178-9