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Current evidence on the management of ischaemic priapism post-shunting: a narrative review

Schifano, Nicolò, Capogrosso, Paolo, Baldini, Sara, Villano, Alessio, Cakir, Onur Omer, Castiglione, Fabio, Antonini, Gabriele, Dehò, Federico·2026·International Journal of Impotence Research
DOI 10.1038/s41443-025-01078-7
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  1. Broderick GA, Kadioglu A, Bivalacqua TJ, Ghanem H, Nehra A, Shamloul R. Priapism: pathogenesis, epidemiology, and management. J Sex Med. 2010;7:476–500. · DOI · Paper page
  2. Eland IA, Van der Lei J, Stricker BHC, Sturkenboom MJCM. Incidence of priapism in the general population. Urology. 2001;57:970–2. · DOI
  3. Bartsch GJ, Kuefer R, Engel O, Volkmer BG. High-flow priapism: colour-Doppler ultrasound-guided supraselective embolization therapy. World J Urol. 2004;22:368–70. · DOI
  4. Ralph DJ, Garaffa G, Muneer A, Freeman A, Rees R, Christopher AN, et al. The immediate insertion of a penile prosthesis for acute ischaemic priapism. Eur Urol. 2009;56:1033–8. · DOI
  5. Olujohungbe AB, Adeyoju A, Yardumian A, Akinyanju O, Morris J, Westerdale N, et al. A prospective diary study of stuttering priapism in adolescents and young men with sickle cell anemia: report of an international randomized control trial–the priapism in sickle cell study. J Androl. 2011;32:375–82. · DOI
  6. Roghmann F, Becker A, Sammon JD, Ouerghi M, Sun M, Sukumar S, et al. Incidence of priapism in emergency departments in the United States. J Urol. 2013;190:1275–80. · DOI
  7. Schifano N, Capogrosso P, Boeri L, Fallara G, Cakir OO, Castiglione F, et al. Medications mostly associated with priapism events: assessment of the 2015–2020 food and drug administration (FDA) pharmacovigilance database entries. Int J Impot Res. 2024;36:50–4. · DOI · Paper page
  8. James Johnson M, Hallerstrom M, Alnajjar HM, Frederick Johnson T, Skrodzka M, Chiriaco G, et al. Which patients with ischaemic priapism require further investigation for malignancy? Int J Impot Res. 2020;32:195–200. · DOI
  9. Muneer A, Minhas S, Freeman A, Kumar P, Ralph DJ. Investigating the effects of high-dose phenylephrine in the management of prolonged ischaemic priapism. J Sex Med. 2008;5:2152–9. · DOI
  10. Broderick GA, Gordon D, Hypolite J, Levin RM. Anoxia and corporal smooth muscle dysfunction: a model for ischemic priapism. J Urol. 1994;151:259–62. · DOI
  11. Ortaç M, Çevik G, Akdere H, Ermeç B, Kadıoğlu A. Anatomic and functional outcome following distal shunt and tunneling for treatment ischemic priapism: a single-center experience. J Sex Med. 2019;16:1290–6. · DOI
  12. Spycher MA, Hauri D. The ultrastructure of the erectile tissue in priapism. J Urol. 1986;135:142–7. · DOI
  13. Kulmala RV, Tamella TL. Effects of priapism lasting 24 h or longer caused by intracavernosal injection of vasoactive drugs. Int J Impot Res. 1995;7:131–6.
  14. Costa WS, Felix B, Cavalcanti AG, Medeiros JJ, Sampaio FJ. Structural analysis of the corpora cavernosa in patients with ischaemic priapism. BJU Int. 2010;105:838–41. · DOI
  15. Zacharakis E, Raheem AA, Freeman A, Skolarikos A, Garaffa G, Christopher AN, et al. The efficacy of the T-shunt procedure and intracavernous tunneling (snake maneuver) for refractory ischemic priapism. J Urol. 2014;191:164–8. · DOI · Paper page
  16. Garcia MM, Shindel AW, Lue TF. T-shunt with or without tunnelling for prolonged ischaemic priapism. BJU Int. 2008;102:1754–64. · DOI
  17. Winter CC. Priapism treated by modification of creation of fistulas between glans penis and corpora cavernosa. J Urol. 1979;121:743–4. · DOI
  18. Quackels R. Treatment of a case of priapism by cavernospongious anastomosis. Acta Urol Belg. 1964;32:5–13.
  19. Grayhack JT, Mccullough W, O’Conor VJJ, Trippel O. Venous bypass to control priapism. Invest Urol. 1964;1:509–13.
  20. Nixon RG, O’Connor JL, Milam DF. Efficacy of shunt surgery for refractory low flow priapism: a report on the incidence of failed detumescence and erectile dysfunction. J Urol. 2003;170:883–6. · DOI
  21. Tabibi A, Abdi H, Mahmoudnejad N. Erectile function and dysfunction following low flow priapism: a comparison of distal and proximal shunts. Urol J. 2010;7:174–7.
  22. Salem EA, El Aasser O. Management of ischemic priapism by penile prosthesis insertion: prevention of distal erosion. J Urol. 2010;183:2300–3. · DOI
  23. Briganti A, Gallina A, Suardi N, Capitanio U, Tutolo M, Bianchi M, et al. Predicting erectile function recovery after bilateral nerve sparing radical prostatectomy: a proposal of a novel preoperative risk stratification. J Sex Med. 2010;7:2521–31. · DOI
  24. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts male aging study. J Urol. 1994;151:54–61. · DOI · Paper page
  25. Montorsi F, Adaikan G, Becher E, Giuliano F, Khoury S, Lue TF, et al. Summary of the recommendations on sexual dysfunctions in men. J Sex Med. 2010;7:3572–88. · DOI
  26. Ralph DJ, Borley NC, Allen C, Kirkham A, Freeman A, Minhas S, et al. The use of high-resolution magnetic resonance imaging in the management of patients presenting with priapism. BJU Int. 2010;106:1714–8. · DOI
  27. Butaney M, Thirumavalavan N, Rodriguez D, Gross MS, Munarriz R. Current practice in the management of ischemic priapism: an anonymous survey of ISSM members. Int J Impot Res. 2019;31:404–9. · DOI
  28. Milenkovic U, Cocci A, Veeratterapillay R, Dimitropoulos K, Boeri L, Capogrosso P, et al. Surgical and minimally invasive treatment of ischaemic and non-ischaemic priapism: a systematic review by the EAU sexual and reproductive health guidelines panel. Int J Impot Res. 2024;36:36–49. · DOI
  29. Segal RL, Readal N, Pierorazio PM, Burnett AL, Bivalacqua TJ. Corporal burnett “Snake” surgical maneuver for the treatment of ischemic priapism: long-term followup. J Urol. 2013;189:1025–9. · DOI
  30. Brant WO, Garcia MM, Bella AJ, Chi T, Lue TF. T-shaped shunt and intracavernous tunneling for prolonged ischemic priapism. J Urol. 2009;181:1699–705. · DOI
  31. Müller A. al-Ghorab shunt for priapism. J Sex Med. 2016;13:1279–84. · DOI
  32. Lutz A, Lacour S, Hellstrom W. Conversion of low-flow to high-flow priapism: a case report and review (CME). J Sex Med. 2012;9:951–4. · DOI
  33. Mistry NA, Tadros NN, Hedges JC. Conversion of low-flow priapism to high-flow state using t-shunt with tunneling. Case Rep Urol. 2017;2017:7394185.
  34. Cahn D, Courter E, Diorio G, Metro M, Ginsberg P. Case report: conversion of a low-flow to high-flow priapism. Curr Urol. 2015;8:101–3. · DOI
  35. Wallis CJD, Hoag N, Pommerville PJ, Huk ME. Recurrent idiopathic high-flow priapism treated with selective arterial embolization after repeated initial treatments for low-flow priapism. Can Urol Assoc J. 2009;3:60–3. · DOI
  36. Rodríguez J, Cuadrado JM, Frances A, Franco E. High-flow priapism as a complication of a veno-occlusive priapism: two case reports. Int J Impot Res. 2006;18:215–7. · DOI
  37. Bertolotto M, Ciampalini S, Martingano P, Mucelli FP. High-flow priapism complicating ischemic priapism following iatrogenic laceration of the dorsal artery during a winter procedure. J Clin Ultrasound. 2009;37:61–4. · DOI
  38. Vagnoni V, Franceschelli A, Gentile G, Palmisano F, Renzulli M, Cappelli A, et al. High-flow priapism after T-shunt and tunneling in a patient with ischemic priapism. Turk J Urol. 2020;46:488–91. · DOI
  39. Idris IM, Burnett AL, DeBaun MR. Epidemiology and treatment of priapism in sickle cell disease. Hematology Am Soc Hematol Educ Program. 2022;2022:450–8. · DOI
  40. Broderick GA. Priapism and sickle-cell anemia: diagnosis and nonsurgical therapy. J Sex Med. 2012;9:88–103. · DOI
  41. Lue TF, Garcia M. Should perioperative anticoagulation be an integral part of the priapism shunting procedure? Transl Androl Urol. 2013;2:316–20.
  42. Ramstein JJ, Lee A, Cohen AJ, Mmonu NA, Rios N, Enriquez A, et al. Clinical outcomes of periprocedural antithrombotic therapy in ischemic priapism management. J Sex Med. 2020;17:2260–6. · DOI
  43. Sherrer R, Otto M, Srinivasan S, Grinde K, Farhat WA. Acute management of prolonged, recalcitrant priapism in a pediatric patient. Pediatrics. 2022;149:e2021054941. · DOI
  44. Sacher EC, Sayegh E, Frensilli F, Crum P, Akers R. Cavernospongiosum shunt in the treatment of priapism. J Urol. 1972;108:97–100. · DOI
  45. Barry JM. Priapism: treatment with corpus cavernosum to dorsal vein of penis shunts. J Urol. 1976;116:754–6. · DOI
  46. Fuchs JS, Shakir N, McKibben MJ, Mathur S, Teeple S, Scott JM, et al. Penoscrotal decompression-promising new treatment paradigm for refractory ischemic priapism. J Sex Med. 2018;15:797–802. · DOI
  47. Baumgarten AS, VanDyke ME, Yi YA, Keith CG, Fuchs JS, Ortiz NM, et al. Favourable multi-institutional experience with penoscrotal decompression for prolonged ischaemic priapism. BJU Int. 2020;126:441–6. · DOI
  48. VanDyke ME, Smith WJ, Holland LC, Langford BT, Joshi EG, Dropkin BM, et al. Current opinions on the management of prolonged ischemic priapism: does penoscrotal decompression outperform corporoglanular tunneling? Int J Impot Res. 2024;36:62–7. · DOI
  49. Zheng D-C, Yao H-J, Zhang K, Xu M-X, Chen Q, Chen Y-B, et al. Unsatisfactory outcomes of prolonged ischemic priapism without early surgical shunts: our clinical experience and a review of the literature. Asian J Androl. 2013;15:75–8. · DOI
  50. Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism. Urology. 2006;67:1043–8. · DOI
  51. Champion HC, Bivalacqua TJ, Takimoto E, Kass DA, Burnett AL. Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism. Proc Natl Acad Sci USA. 2005;102:1661–6. · DOI
  52. Burnett AL, Anele UA, Trueheart IN, Strouse JJ, Casella JF. Randomized controlled trial of sildenafil for preventing recurrent ischemic priapism in sickle cell disease. Am J Med. 2014;127:664–8. · DOI
  53. Brant WO, Dean RC, Lue TF. Treatment of Peyronie’s disease with oral pentoxifylline. Nat Clin Pract Urol. 2006;3:111–5. · DOI
  54. Zahran A-R, Abdel Daiem H, Youssif M. Does pentoxifylline enhance the recovery of erectile function after a T-shunt procedure for prolonged ischaemic priapism? A prospective randomised controlled trial. Arab J Urol. 2012;10:425–8. · DOI
  55. Zacharakis E, Garaffa G, Raheem AA, Christopher AN, Muneer A, Ralph DJ. Penile prosthesis insertion in patients with refractory ischaemic priapism: early vs delayed implantation. BJU Int. 2014;114:576–81. · DOI
  56. Capece M, Gillo A, Cocci A, Garaffa G, Timpano M, Falcone M. Management of refractory ischemic priapism: current perspectives. Res Rep Urol. 2017;9:175–9.
  57. La Croce G, Schifano N, Pescatori E, Caraceni E, Colombo F, Bettocchi C, et al. Which patient may benefit the most from penile prosthesis implantation? Andrology. 2022;10:1567–74. · DOI
  58. Sedigh O, Rolle L, Negro CLA, Ceruti C, Timpano M, Galletto E, et al. Early insertion of inflatable prosthesis for intractable ischemic priapism: our experience and review of the literature. Int J Impot Res. 2011;23:158–64. · DOI
  59. Capece M, Falcone M, Cai T, Palmieri A, Cocci A, La Rocca R. Penile prosthesis implantation in refractory ischaemic priapism: patient selection and special considerations. Res Rep Urol. 2022;14:1–6.
  60. Tausch TJ, Zhao LC, Morey AF, Siegel JA, Belsante MJ, Seideman CA, et al. Malleable penile prosthesis is a cost-effective treatment for refractory ischemic priapism. J Sex Med. 2015;12:824–6. · DOI
  61. Wilson SK, Delk JR, Mulcahy JJ, Cleves M, Salem EA. Upsizing of inflatable penile implant cylinders in patients with corporal fibrosis. J Sex Med. 2006;3:736–42. · DOI
  62. Antonini G, De Berardinis E, Del Giudice F, Busetto GM, Lauretti S, Fragas R, et al. Inflatable penile prosthesis placement, scratch technique and postoperative vacuum therapy as a combined approach to definitive treatment of Peyronie’s disease. J Urol. 2018;200:642–7. · DOI
  63. Del Giudice F, Busetto GM, Chung BI, Conti SL, Ferro M, Maggi M, et al. Non-ischemic priapism following recurrent idiopathic ischemic priapism treated successfully with selective arterial embolization and postoperative vacuum therapy before delayed inflatable penile prosthesis placement: a single case report. IJU Case Rep. 2018;1:13–5. · DOI
  64. Tsambarlis PN, Chaus F, Levine LA. Successful placement of penile prostheses in men with severe corporal fibrosis following vacuum therapy protocol. J Sex Med. 2017;14:44–6. · DOI
  65. Sansalone S, Garaffa G, Djinovic R, Antonini G, Vespasiani G, Ieria FP, et al. Simultaneous total corporal reconstruction and implantation of a penile prosthesis in patients with erectile dysfunction and severe fibrosis of the corpora cavernosa. J Sex Med. 2012;9:1937–44. · DOI
  66. Sellers T, Dineen M, Salem EA, Wilson SK. Vacuum preparation, optimization of cylinder length and postoperative daily inflation reduces complaints of shortened penile length following implantation of inflatable penile prosthesis. Adv Sex Med. 2013;03:14–8. · DOI
  67. Muneer A. Insertion of penile implants in patients with priapism: when is the right time? Eur Urol Focus. 2023;9:49–50. · DOI
  68. Tausch TJ, Mauck R, Zhao LC, Morey AF. Penile prosthesis insertion for acute priapism. Urol Clin North Am. 2013;40:421–5. · DOI
  69. Knoll LD, Furlow WL. Corporeal reconstruction and prosthetic implantation for impotence associated with non-dilatable corporeal cavernosal fibrosis. Acta Urol Belg. 1992;60:15–25.
  70. Knoll LD, Furlow WL, Benson RCJ, Bilhartz DL. Management of nondilatable cavernous fibrosis with the use of a downsized inflatable penile prosthesis. J Urol. 1995;153:366–7. · DOI
  71. Carbone DJJ, Daitch JA, Angermeier KW, Lakin MM, Montague DK. Management of severe corporeal fibrosis with implantation of prosthesis via a transverse scrotal approach. J Urol. 1998;159:125–7. · DOI
  72. Wilson SK, Simhan J, Gross MS. Cylinder insertion into scarred corporal bodies: prosthetic urology’s most difficult challenge: some suggestions for making the surgery easier. Int J Impot Res. 2020;32:483–94. · DOI
  73. Ralph DJ. Words of wisdom. Re: upsizing of inflatable penile implant cylinders in patients with corporal fibrosis. Eur Urol. 2007;52:1259. · DOI
  74. Schifano N, Capogrosso P, Cakir OO, Dehò F, Garaffa G. Surgical tips in difficult penile prosthetic surgery: a narrative review. Int J Impot Res. 2023;35:690–8. · DOI
  75. Wilson SK, Levine L, Wang R. “Make it as long as you can, Doc.” concomitant surgical treatments with penile implant to enhance penile size. Int J Impot Res. 2021;33:587–95. · DOI
  76. Garber BB, Lim C. Inflatable penile prosthesis insertion in men with severe intracorporal fibrosis. Curr Urol. 2017;10:92–6. · DOI
  77. Shaeer O, Shaeer A. Corporoscopic excavation of the fibrosed corpora cavernosa for penile prosethesis implantation: optical corporotomy and trans-corporeal resection, Shaeer’s technique. J Sex Med. 2007;4:218–25. · DOI
  78. Andrianne R, Hubert C, Ben MA, Chehida M, Sempels LC, Waltregny D. Use of a wire loop monopolar electrode for open, visual excavation in severe corporeal penile fibrosis before penile prosthesis implantation. VJPU. 2017;2:101.
  79. Lopes EJA, Kuwano AY, Guimaraes AN, Flores JP, Jacobino MAO. Corporoplasty using bovine pericardium grafts in complex penile prosthesis implantation surgery. Int Braz J Urol. 2009;35:45–9. · DOI
  80. Palese MA, Burnett AL. Corporoplasty using pericardium allograft (tutoplast) with complex penile prosthesis surgery. Urology. 2001;58:1049–52. · DOI
  81. Garaffa G, Ralph DJ. Penile prosthesis implantation in acute and chronic priapism. Sex Med Rev. 2013;1:76–82. · DOI
  82. Lentz AC, Carson CC 3rd. Peyronie’s surgery: graft choices and outcomes. Curr Urol Rep. 2009;10:460–7. · DOI

Cited by

Metadata

Authors
Schifano, N., Capogrosso, P., Baldini, S., Villano, A., Cakir, O. O., Castiglione, F., Antonini, G., & Dehò, F.
Venue
International Journal of Impotence Research
Publisher
Springer Science and Business Media LLC
Published
2025-04-29
Volume
38
Issue
9
Pages
654-661
ISSN
  • 0955-9930
  • 1476-5489
DOI
10.1038/s41443-025-01078-7
Cited by
2
References
0
Language
en
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