The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases
Open accessAbstract
Reports on bacteria detected in maternal fluids during pregnancy are typically associated with adverse consequences, and whether the female reproductive tract harbours distinct microbial communities beyond the vagina has been a matter of debate. Here we systematically sample the microbiota within the female reproductive tract in 110 women of reproductive age, and examine the nature of colonisation by 16S rRNA gene amplicon sequencing and cultivation. We find distinct microbial communities in cervical canal, uterus, fallopian tubes and peritoneal fluid, differing from that of the vagina. The results reflect a microbiota continuum along the female reproductive tract, indicative of a non-sterile environment. We also identify microbial taxa and potential functions that correlate with the menstrual cycle or are over-represented in subjects with adenomyosis or infertility due to endometriosis. The study provides insight into the nature of the vagino-uterine microbiome, and suggests that surveying the vaginal or cervical microbiota might be useful for detection of common diseases in the upper reproductive tract.
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QIIME allows analysis of high-throughput community sequencing data
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A new method for non-parametric multivariate analysis of variance
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A metagenome-wide association study of gut microbiota in type 2 diabetes
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Self-citationVaginal microbiome of reproductive-age women
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Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life
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Self-citationIntrauterine infection and preterm delivery
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Robertson, R. C., Manges, A. R., Finlay, B. B., & Prendergast, A. J. (2019) · Trends in Microbiology · doi:10.1016/j.tim.2018.09.008 · Cited by 793
The Female Vaginal Microbiome in Health and Bacterial Vaginosis
Chen, X., Lu, Y., Chen, T., & Li, R. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.631972 · Cited by 451
Self-citationMenstruation: science and society
Critchley, H. O. D., Babayev, E., Bulun, S. E., Clark, S., Garcia-Grau, I., Gregersen, P. K., Kilcoyne, A., Kim, J.-Y. J., Lavender, M., Marsh, E. E., et al. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.06.004 · Cited by 448
Vulvovaginal Candidiasis: A Current Understanding and Burning Questions
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Metadata
- Authors
- Chen, C., Song, X., Wei, W., Zhong, H., Dai, J., Lan, Z., Li, F., Yu, X., Feng, Q., Wang, Z., Xie, H., Chen, X., Zeng, C., Wen, B., Zeng, L., Du, H., Tang, H., Xu, C., Xia, Y., Xia, H., Yang, H., Wang, J., Wang, J., Madsen, L., Brix, S., Kristiansen, K., Xu, X., Li, J., Wu, R., & Jia, H.
- Venue
- Nature Communications
- Published
- 2017-10-17
- Volume
- 8
- Issue
- 1
- Pages
- 875-875
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W2761875562
- Cited by
- 984
- References
- 42
- FWCI
- 36.25
- Type
- journal article
- Language
- en
- Open access
- gold
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- Chen, C., Song, X., Wei, W., Zhong, H., Dai, J., Lan, Z., Li, F., Yu, X., Feng, Q., Wang, Z., Xie, H., Chen, X., Zeng, C., Wen, B., Zeng, L., Du, H., Tang, H., Xu, C., Xia, Y., . . . Jia, H. (2017). The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases. Nature Communications. https://doi.org/10.1038/s41467-017-00901-0
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
