Colonization of the human gut by bovine bacteria present in Parmesan cheese
Open accessAbstract
The abilities of certain microorganisms to be transferred across the food production chain, persist in the final product and, potentially, colonize the human gut are poorly understood. Here, we provide strain-level evidence supporting that dairy cattle-associated bacteria can be transferred to the human gut via consumption of Parmesan cheese. We characterize the microbial communities in samples taken from five different locations across the Parmesan cheese production chain, confirming that the final product contains microorganisms derived from cattle gut, milk, and the nearby environment. In addition, we carry out a human pilot study showing that Bifidobacterium mongoliense strains from cheese can transiently colonize the human gut, a process that can be enhanced by cow milk consumption.
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References 56 · Cited by 78
- Authors
- Milani, C., Duranti, S., Napoli, S., Alessandri, G., Mancabelli, L., Anzalone, R., Longhi, G., Viappiani, A., Mangifesta, M., Lugli, G. A., Bernasconi, S., Ossiprandi, M. C., van Sinderen, D., Ventura, M., & Turroni, F.
- Affiliations
- University of Parma (IT)
- Corresponding author
- Ventura, Marco
- Turroni, Francesca
- ORCID
- Venue
- Nature Communications
- Published
- 2019-03-20
- Volume
- 10
- Issue
- 1
- Pages
- 1286-1286
- ISSN
- 2041-1723 (ISSN-L)
- PMC
- PMC6426854
- OpenAlex
- W2923104433
- Cited by
- 78
- References
- 56
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 9 · 2023: 18 · 2022: 8 · 2021: 10 · 2020: 12 · 2019: 2
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Nature Communications (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Arrow@dit (Dublin Institute of Technology) (submittedVersion, cc-by)
- HAL (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Cork Open Research Archive (University College Cork, Ireland) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Fondazione Cariparma
- Joint Programming Initiative A healthy diet for a healthy life (15/JP-HDHL/3280)
- Science Foundation Ireland (15/JP-HDHL/3280)
- Ministero dell’Istruzione, dell’Università e della Ricerca
- Università degli Studi di Parma
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Safety and Hygiene
- Keywords
- Parmesan cheese, food production chain, microbial transmission, gut microbiota, dairy microbiology
- MeSH terms
- Gastrointestinal Microbiome, Animals, Bifidobacterium, Cattle, Cheese, Corynebacterium, DNA, Bacterial, Feces, Humans, Milk, Phylogeny, Pilot Projects, RNA, Ribosomal, 16S, Prevotella ruminicola, Streptococcus thermophilus, Lactobacillus delbrueckii, DNA Barcoding, Taxonomic
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