The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Ultralong purely organic aqueous phosphorescence supramolecular polymer for targeted tumor cell imaging
Open accessAbstract
Purely organic room-temperature phosphorescence has attracted attention for bioimaging but can be quenched in aqueous systems. Here we report a water-soluble ultralong organic room-temperature phosphorescent supramolecular polymer by combining cucurbit[n]uril (CB[7], CB[8]) and hyaluronic acid (HA) as a tumor-targeting ligand conjugated to a 4-(4-bromophenyl)pyridin-1-ium bromide (BrBP) phosphor. The result shows that CB[7] mediated pseudorotaxane polymer CB[7]/HA–BrBP changes from small spherical aggregates to a linear array, whereas complexation with CB[8] results in biaxial pseudorotaxane polymer CB[8]/HA–BrBP which transforms to relatively large aggregates. Owing to the more stable 1:2 inclusion complex between CB[8] and BrBP and the multiple hydrogen bonds, this supramolecular polymer has ultralong purely organic RTP lifetime in water up to 4.33 ms with a quantum yield of 7.58%. Benefiting from the targeting property of HA, this supramolecular polymer is successfully applied for cancer cell targeted phosphorescence imaging of mitochondria.
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Cited by
Garain, S., Garain, B. C., Eswaramoorthy, M., Pati, S. K., & George, S. J. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202107295 · Cited by 259
He, M., Ding, C., Guo, H., & Li, Q. (2024) · Responsive Materials · doi:10.1002/rpm.20240014 · Cited by 71
Metadata
- Authors
- Zhou, W.-L., Chen, Y., Yu, Q., Zhang, H., Liu, Z.-X., Dai, X.-Y., Li, J.-J., & Liu, Y.
- Venue
- Nature Communications
- Published
- 2020-09-16
- Volume
- 11
- Issue
- 1
- Pages
- 4655-4655
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W3087405767
- Cited by
- 308
- References
- 46
- FWCI
- 16.03
- Type
- journal article
- Language
- en
- Open access
- gold
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