The DOI matches its Crossref record; 185 of the 185 references it cites were found in a registry or an index.
Engineering microrobots for targeted cancer therapies from a medical perspective
Open accessAbstract
Systemic chemotherapy remains the backbone of many cancer treatments. Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine approaches have been developed to overcome these issues. However, targeted delivery of therapeutics remains challenging. Engineering microrobots is increasingly receiving attention in this regard. Their functionalities, particularly their motility, allow microrobots to penetrate tissues and reach cancers more efficiently. Here, we highlight how different microrobots, ranging from tailor-made motile bacteria and tiny bubble-propelled microengines to hybrid spermbots, can be engineered to integrate sophisticated features optimised for precision-targeting of a wide range of cancers. Towards this, we highlight the importance of integrating clinicians, the public and cancer patients early on in the development of these novel technologies.
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Cited by
Ali, A., Shah, T., Ullah, R., Zhou, P., Guo, M., Ovais, M., Tan, Z., & Rui, Y. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.629054 · Cited by 650
Dual-responsive biohybrid neutrobots for active target delivery
Zhang, H., Li, Z., Gao, C., Fan, X., Pang, Y., Li, T., Wu, Z., Xie, H., & He, Q. (2021) · Science Robotics · doi:10.1126/scirobotics.aaz9519 · Cited by 518
Ultrasound-activated ciliary bands for microrobotic systems inspired by starfish
Dillinger, C., Nama, N., & Ahmed, D. (2021) · Nature Communications · doi:10.1038/s41467-021-26607-y · Cited by 149
Magnetic Nanostructures: Rational Design and Fabrication Strategies toward Diverse Applications
Wang, S., Xu, J., Li, W., Sun, S., Gao, S., & Hou, Y. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00370 · Cited by 129
Peng, Q., Wang, S., Han, J., Huang, C., Yu, H., Li, D., Qiu, M., Cheng, S., Wu, C., Cai, M., et al. (2024) · Research · doi:10.34133/research.0339 · Cited by 89
Metadata
- Authors
- Schmidt, C. K., Medina-Sánchez, M., Edmondson, R. J., & Schmidt, O. G.
- Venue
- Nature Communications
- Published
- 2020-11-05
- Volume
- 11
- Issue
- 1
- Pages
- 5618-5618
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W3095620052
- Cited by
- 441
- References
- 185
- FWCI
- 51.41
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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