Lipid rafts come of age
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Plasma membrane lipids are not homogeneously distributed but segregated; lipid rafts are platforms enriched in cholesterol and sphingolipids where signalling proteins can accumulate.
“Our understanding of the plasma membrane has evolved with the recognition that the lipids are not homogeneously distributed but are segregated; one early concept was ‘lipid rafts’ as platforms enriched in cholesterol and sphingolipids, in which specific proteins involved in signalling can accumulate [122,123].”
From Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane (2020) · cites this paper as [123]
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Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane
Katan, M., & Cockcroft, S. (2020) · Essays in Biochemistry · doi:10.1042/ebc20200041 · Cited by 176 · see citing works
- Authors
- Levental, I.
- Affiliations
- The University of Texas Health Science Center at Houston (US)
- Corresponding author
- Levental, Ilya
- ORCID
- Levental, Ilya
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2020-04-29
- Volume
- 21
- Issue
- 8
- Pages
- 420-420
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W3022531898
- Cited by
- 41
- References
- 0
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 7 · 2023: 5 · 2022: 4 · 2021: 5 · 2020: 6
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature Reviews Molecular Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Lipid Membrane Structure and Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Caveolin-1 and cellular processes
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Sphingolipid Metabolism and Signaling
- Keywords
- lipid rafts
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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