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Cited by 13Inflammasome and immune disordersAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

NLRP3 inflammasome activation implicated in tau pathology

Lemprière, Sarah·2020·Nature Reviews Neurology
DOI 10.1038/s41582-019-0299-5
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Crossref · 10.1038/s41582-019-0299-5

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  • Mitochondrial abnormalities, synaptic loss and dysfunction, altered axonal transport, and activation of cell death pathways have been implicated as consequences of tau mislocalization or oligomerization.

    “Mitochondrial abnormalities, synaptic loss and dysfunction, altered axonal transport, and activation of cell death pathways (including caspase activation and inflammatory responses) have all been directly or indirectly implicated as consequences of tau mislocalization or oligomerization (20, 40, 43–52).”

    From All the Tau We Cannot See (2023) · cites this paper as [47]

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References 1 · Cited by 13

Authors
Lemprière, S.
Corresponding author
Lemprière, Sarah
ORCID
Lemprière, Sarah
Venue
Nature Reviews Neurology
Publisher
Springer Science and Business Media LLC
Published
2019-12-06
Volume
16
Issue
1
Pages
4-4
ISSN
  • 1759-4758 (ISSN-L)
  • 1759-4766
DOI
10.1038/s41582-019-0299-5
OpenAlex
W2994561443
Cited by
13
References
1
Citations by year
2026: 2 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 1
FWCI
0.58
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Nature Reviews Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Inflammasome and immune disorders
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Keywords
NLRP3 inflammasome, tau pathology, neuroinflammation, Alzheimer's disease, neurodegeneration
MeSH terms
NLR Family, Pyrin Domain-Containing 3 Protein, Humans, Inflammation, Mitochondria, Inflammasomes

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